Mus musculus

0 known processes

Klra4

killer cell lectin-like receptor, subfamily A, member 4

(Aliases: ly49r<129>,Ly49d,Chok,Klra32)

Klra4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipopolysaccharide GO:0071222 77 0.079
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.076
response to lipopolysaccharide GO:0032496 128 0.075
Mouse
cellular lipid metabolic process GO:0044255 323 0.070
cellular response to molecule of bacterial origin GO:0071219 83 0.069
Mouse
cytokine production GO:0001816 319 0.065
Mouse
cellular ketone metabolic process GO:0042180 84 0.061
cell adhesion GO:0007155 329 0.056
Mouse
regulation of defense response GO:0031347 233 0.053
Mouse
innate immune response GO:0045087 157 0.052
Mouse
cellular amino acid metabolic process GO:0006520 103 0.052
leukocyte mediated cytotoxicity GO:0001909 62 0.051
Mouse
regulation of cytokine production GO:0001817 266 0.051
Mouse
lymphocyte mediated immunity GO:0002449 139 0.047
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
cellular response to biotic stimulus GO:0071216 92 0.044
Mouse
immune effector process GO:0002252 321 0.044
Mouse
oxidation reduction process GO:0055114 342 0.043
defense response to other organism GO:0098542 197 0.043
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.041
leukocyte activation involved in immune response GO:0002366 126 0.040
Mouse
activation of immune response GO:0002253 138 0.040
Mouse
cellular response to lipid GO:0071396 145 0.040
Mouse
membrane organization GO:0061024 245 0.040
Mouse
cellular amine metabolic process GO:0044106 44 0.039
leukocyte mediated immunity GO:0002443 174 0.039
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.039
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.039
reactive nitrogen species metabolic process GO:2001057 0 0.038
detection of yeast GO:0001879 2 0.038
Mouse
inflammatory response GO:0006954 244 0.037
cellular response to cytokine stimulus GO:0071345 189 0.037
response to molecule of bacterial origin GO:0002237 143 0.037
Mouse
cell recognition GO:0008037 83 0.037
Mouse
apoptotic signaling pathway GO:0097190 306 0.035
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.035
Mouse
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.034
Mouse
positive regulation of cytokine production GO:0001819 174 0.034
Mouse
cell killing GO:0001906 67 0.034
Mouse
macromolecule catabolic process GO:0009057 281 0.034
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.032
Mouse
single organism cell adhesion GO:0098602 156 0.032
Mouse
amine metabolic process GO:0009308 45 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
negative regulation of immune system process GO:0002683 209 0.031
immune response regulating signaling pathway GO:0002764 125 0.031
Mouse
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.030
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.029
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.029
lipid biosynthetic process GO:0008610 179 0.029
regulation of homeostatic process GO:0032844 182 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
sensory perception GO:0007600 245 0.029
action potential GO:0001508 78 0.028
regulation of innate immune response GO:0045088 91 0.028
Mouse
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.028
cellular response to molecule of fungal origin GO:0071226 2 0.028
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.028
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.028
Mouse
axonogenesis GO:0007409 274 0.027
detection of fungus GO:0016046 2 0.027
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.027
transmembrane transport GO:0055085 412 0.027
aromatic compound catabolic process GO:0019439 286 0.027
regulation of membrane potential GO:0042391 192 0.027
regulation of lymphocyte activation GO:0051249 240 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
interferon gamma production GO:0032609 67 0.026
Mouse
immune response activating signal transduction GO:0002757 116 0.026
Mouse
protein processing GO:0016485 163 0.026
dna metabolic process GO:0006259 303 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
regulation of kinase activity GO:0043549 249 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
muscle tissue development GO:0060537 308 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
cell activation involved in immune response GO:0002263 126 0.025
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.025
Mouse
regulation of secretion GO:0051046 274 0.025
nucleotide metabolic process GO:0009117 332 0.025
carbohydrate metabolic process GO:0005975 230 0.024
striated muscle tissue development GO:0014706 293 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
cellular homeostasis GO:0019725 240 0.024
leukocyte proliferation GO:0070661 172 0.024
regulation of organelle organization GO:0033043 289 0.024
heterocycle catabolic process GO:0046700 280 0.023
mapk cascade GO:0000165 281 0.023
protein maturation GO:0051604 176 0.023
multicellular organismal signaling GO:0035637 91 0.023
male gamete generation GO:0048232 285 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
myeloid cell differentiation GO:0030099 233 0.022
Mouse
defense response to gram positive bacterium GO:0050830 50 0.022
Mouse
positive regulation of protein modification process GO:0031401 299 0.022
leukocyte differentiation GO:0002521 342 0.022
negative regulation of molecular function GO:0044092 258 0.022
positive regulation of defense response GO:0031349 124 0.022
Mouse
protein localization to organelle GO:0033365 185 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
germ cell development GO:0007281 185 0.022
regulation of hydrolase activity GO:0051336 246 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
adaptive immune response GO:0002250 155 0.021
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.021
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.021
peptidyl amino acid modification GO:0018193 336 0.021
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.021
Mouse
purine containing compound metabolic process GO:0072521 311 0.021
regulation of hormone levels GO:0010817 211 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
response to organonitrogen compound GO:0010243 246 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
fatty acid metabolic process GO:0006631 121 0.020
regulation of lymphocyte mediated immunity GO:0002706 84 0.020
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.020
regulation of secretion by cell GO:1903530 249 0.020
response to testosterone GO:0033574 3 0.020
cell type specific apoptotic process GO:0097285 268 0.020
regulation of cell activation GO:0050865 289 0.020
blood circulation GO:0008015 195 0.020
fertilization GO:0009566 127 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of protein transport GO:0051223 163 0.019
spermatogenesis GO:0007283 284 0.019
endocytosis GO:0006897 168 0.019
Mouse
chemotaxis GO:0006935 247 0.019
nuclear division GO:0000280 158 0.019
regulation of inflammatory response GO:0050727 147 0.019
transmission of nerve impulse GO:0019226 76 0.018
ear development GO:0043583 200 0.018
positive regulation of immune effector process GO:0002699 107 0.018
Mouse
regulation of mapk cascade GO:0043408 248 0.018
maintenance of location GO:0051235 89 0.018
positive regulation of cell killing GO:0031343 33 0.018
Mouse
organelle fission GO:0048285 170 0.018
regulation of transferase activity GO:0051338 263 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
natural killer cell activation GO:0030101 44 0.018
Mouse
defense response to bacterium GO:0042742 119 0.018
Mouse
ribonucleotide metabolic process GO:0009259 291 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
multicellular organismal homeostasis GO:0048871 164 0.017
regulation of response to wounding GO:1903034 189 0.017
regulation of cell migration GO:0030334 219 0.017
sequestering of calcium ion GO:0051208 18 0.017
blood vessel morphogenesis GO:0048514 285 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
regulation of cell cycle GO:0051726 281 0.017
stem cell development GO:0048864 219 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
positive regulation of leukocyte mediated immunity GO:0002705 70 0.017
Mouse
muscle cell differentiation GO:0042692 261 0.017
cellular chemical homeostasis GO:0055082 215 0.017
calcium ion homeostasis GO:0055074 127 0.017
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.017
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
response to molecule of fungal origin GO:0002238 4 0.017
Mouse
chromatin organization GO:0006325 206 0.017
regulation of protein kinase activity GO:0045859 232 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
Mouse
natural killer cell mediated immunity GO:0002228 29 0.017
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
Mouse
regulation of natural killer cell mediated immunity GO:0002715 19 0.017
Mouse
positive regulation of interferon gamma production GO:0032729 39 0.016
Mouse
positive regulation of t cell activation GO:0050870 101 0.016
regulation of t cell proliferation GO:0042129 92 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
regulation of cell motility GO:2000145 236 0.016
regulation of neuron differentiation GO:0045664 281 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
cation transport GO:0006812 399 0.016
regulation of cell killing GO:0031341 40 0.016
Mouse
positive regulation of transferase activity GO:0051347 167 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
ameboidal type cell migration GO:0001667 128 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
positive regulation of nervous system development GO:0051962 221 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
regulation of interferon gamma production GO:0032649 57 0.016
Mouse
cytoplasmic transport GO:0016482 234 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
divalent metal ion transport GO:0070838 172 0.016
regulation of peptidase activity GO:0052547 96 0.015
sequestering of metal ion GO:0051238 19 0.015
cation homeostasis GO:0055080 212 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
monocyte extravasation GO:0035696 2 0.015
circulatory system process GO:0003013 197 0.015
detection of stimulus GO:0051606 84 0.015
Mouse
response to oxygen levels GO:0070482 62 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
regulation of proteolysis GO:0030162 164 0.015
intracellular protein transport GO:0006886 204 0.015
regulation of t cell activation GO:0050863 170 0.015
endomembrane system organization GO:0010256 147 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
homeostasis of number of cells GO:0048872 210 0.015
leukocyte migration GO:0050900 124 0.015
mitotic cell cycle GO:0000278 195 0.015
ion transmembrane transport GO:0034220 361 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
negative regulation of homeostatic process GO:0032845 71 0.015
ribonucleoside metabolic process GO:0009119 245 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
b cell activation GO:0042113 161 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
t cell activation GO:0042110 289 0.014
ras protein signal transduction GO:0007265 77 0.014
axon guidance GO:0007411 141 0.014
glycerolipid metabolic process GO:0046486 122 0.014
lymphocyte differentiation GO:0030098 242 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
regulation of vasculature development GO:1901342 88 0.014
glucose homeostasis GO:0042593 128 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
positive regulation of cell development GO:0010720 237 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
lymphocyte proliferation GO:0046651 164 0.014
divalent inorganic cation transport GO:0072511 178 0.014
methylation GO:0032259 134 0.014
carbohydrate homeostasis GO:0033500 128 0.014
phospholipid metabolic process GO:0006644 87 0.014
negative regulation of defense response GO:0031348 77 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
response to inorganic substance GO:0010035 96 0.013
cell cell recognition GO:0009988 44 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of protein maturation GO:1903317 96 0.013
nitrogen compound transport GO:0071705 271 0.013
neuronal action potential GO:0019228 54 0.013
microtubule based process GO:0007017 236 0.013
glycoprotein metabolic process GO:0009100 116 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
locomotory behavior GO:0007626 195 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
calcium ion transport GO:0006816 159 0.013
compound eye development GO:0048749 1 0.013
regulation of intracellular transport GO:0032386 159 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
regulation of multi organism process GO:0043900 111 0.013
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.013
Mouse
negative regulation of protein maturation GO:1903318 79 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
tumor necrosis factor production GO:0032640 50 0.013
Mouse
response to drug GO:0042493 75 0.013
Mouse
t cell proliferation GO:0042098 120 0.013
rhythmic process GO:0048511 174 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
skeletal muscle organ development GO:0060538 163 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of cellular response to stress GO:0080135 159 0.012
regulation of protein catabolic process GO:0042176 108 0.012
anatomical structure homeostasis GO:0060249 145 0.012
organelle localization GO:0051640 179 0.012
translation GO:0006412 93 0.012
wnt signaling pathway GO:0016055 188 0.012
regulation of anatomical structure size GO:0090066 178 0.012
activation of innate immune response GO:0002218 56 0.012
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.012
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
negative regulation of proteolysis GO:0045861 74 0.012
macromolecule methylation GO:0043414 120 0.012
purine containing compound catabolic process GO:0072523 213 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.012
Mouse
skeletal system development GO:0001501 356 0.012
regulation of cell adhesion GO:0030155 154 0.012
cognition GO:0050890 149 0.012
regulation of chromosome organization GO:0033044 83 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
negative regulation of protein processing GO:0010955 79 0.012
chromatin modification GO:0016568 187 0.012
hexose metabolic process GO:0019318 98 0.012
rho protein signal transduction GO:0007266 32 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
glucose metabolic process GO:0006006 92 0.012
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.012
Mouse
meiotic cell cycle GO:0051321 122 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
meiotic nuclear division GO:0007126 115 0.012
secondary alcohol metabolic process GO:1902652 3 0.012
nucleoside metabolic process GO:0009116 246 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
positive regulation of innate immune response GO:0045089 80 0.011
Mouse
olfactory learning GO:0008355 2 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
protein catabolic process GO:0030163 221 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
metal ion homeostasis GO:0055065 189 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
epithelial cell development GO:0002064 159 0.011
organophosphate catabolic process GO:0046434 232 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
angiogenesis GO:0001525 201 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
nucleotide catabolic process GO:0009166 217 0.011
monosaccharide metabolic process GO:0005996 106 0.011
regulation of adaptive immune response GO:0002819 90 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
spermatid development GO:0007286 108 0.011
humoral immune response GO:0006959 57 0.011
negative regulation of cell cycle GO:0045786 123 0.011
cytokine metabolic process GO:0042107 71 0.011
positive regulation of kinase activity GO:0033674 155 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
regulation of cytokine biosynthetic process GO:0042035 59 0.011
cellular response to external stimulus GO:0071496 88 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
placenta development GO:0001890 140 0.011
positive regulation of lymphocyte proliferation GO:0050671 70 0.011
calcitriol biosynthetic process from calciol GO:0036378 3 0.011
regulation of ion transport GO:0043269 215 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
myelination GO:0042552 74 0.011
response to extracellular stimulus GO:0009991 127 0.011
natural killer cell mediated cytotoxicity GO:0042267 29 0.011
Mouse
phagocytosis GO:0006909 66 0.011
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.011
extracellular matrix organization GO:0030198 147 0.011
regulation of cell projection organization GO:0031344 206 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.010
positive regulation of organelle organization GO:0010638 128 0.010
regulation of system process GO:0044057 200 0.010
cation transmembrane transport GO:0098655 266 0.010
negative regulation of cell activation GO:0050866 111 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
positive regulation of endocytosis GO:0045807 42 0.010
Mouse
cellular protein complex assembly GO:0043623 116 0.010
protein ubiquitination GO:0016567 171 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
t cell differentiation GO:0030217 174 0.010
protein secretion GO:0009306 111 0.010
spermatid differentiation GO:0048515 115 0.010
positive regulation of cell activation GO:0050867 158 0.010
t cell extravasation GO:0072683 4 0.010
histone modification GO:0016570 159 0.010
respiratory system development GO:0060541 190 0.010
steroid metabolic process GO:0008202 119 0.010
cellular protein catabolic process GO:0044257 155 0.010
small molecule biosynthetic process GO:0044283 132 0.010
cytokine biosynthetic process GO:0042089 68 0.010
gland development GO:0048732 330 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
exocytosis GO:0006887 121 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010

Klra4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of metabolism DOID:0014667 0 0.013
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.013