Mus musculus

148 known processes

Ralgapa2

Ral GTPase activating protein, alpha subunit 2 (catalytic)

(Aliases: KIAA1272,A230067G21Rik,pp250,AS250,BC053994)

Ralgapa2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.066
transmembrane transport GO:0055085 412 0.059
cellular lipid metabolic process GO:0044255 323 0.058
cellular ketone metabolic process GO:0042180 84 0.056
organic cyclic compound catabolic process GO:1901361 295 0.055
nucleoside phosphate metabolic process GO:0006753 338 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
purine ribonucleotide metabolic process GO:0009150 290 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.050
cellular nitrogen compound catabolic process GO:0044270 280 0.048
lipid biosynthetic process GO:0008610 179 0.047
ribonucleotide catabolic process GO:0009261 208 0.047
heterocycle catabolic process GO:0046700 280 0.046
nucleotide metabolic process GO:0009117 332 0.043
ribonucleotide metabolic process GO:0009259 291 0.042
organophosphate catabolic process GO:0046434 232 0.041
oxidation reduction process GO:0055114 342 0.041
cellular amine metabolic process GO:0044106 44 0.041
anion transport GO:0006820 177 0.040
purine nucleotide catabolic process GO:0006195 211 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
small gtpase mediated signal transduction GO:0007264 97 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
ion transmembrane transport GO:0034220 361 0.038
monocarboxylic acid metabolic process GO:0032787 191 0.037
purine nucleotide metabolic process GO:0006163 302 0.037
purine containing compound metabolic process GO:0072521 311 0.037
amine metabolic process GO:0009308 45 0.036
aromatic compound catabolic process GO:0019439 286 0.036
macromolecule catabolic process GO:0009057 281 0.033
cation transport GO:0006812 399 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
ribonucleoside metabolic process GO:0009119 245 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
nucleoside metabolic process GO:0009116 246 0.031
apoptotic signaling pathway GO:0097190 306 0.031
carbohydrate metabolic process GO:0005975 230 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
actin cytoskeleton organization GO:0030036 220 0.030
membrane organization GO:0061024 245 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
regulation of organelle organization GO:0033043 289 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of hydrolase activity GO:0051336 246 0.029
organonitrogen compound catabolic process GO:1901565 264 0.028
nitrogen compound transport GO:0071705 271 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
response to organonitrogen compound GO:0010243 246 0.027
fatty acid metabolic process GO:0006631 121 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
nucleotide catabolic process GO:0009166 217 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
intracellular protein transport GO:0006886 204 0.025
positive regulation of protein modification process GO:0031401 299 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
positive regulation of organelle organization GO:0010638 128 0.023
endomembrane system organization GO:0010256 147 0.023
purine containing compound catabolic process GO:0072523 213 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
cell type specific apoptotic process GO:0097285 268 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
guanosine containing compound catabolic process GO:1901069 144 0.023
organic acid transport GO:0015849 101 0.022
homeostasis of number of cells GO:0048872 210 0.022
nucleoside catabolic process GO:0009164 206 0.022
ras protein signal transduction GO:0007265 77 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
spermatogenesis GO:0007283 284 0.022
glycerolipid metabolic process GO:0046486 122 0.022
small molecule biosynthetic process GO:0044283 132 0.022
cation transmembrane transport GO:0098655 266 0.022
organic anion transport GO:0015711 137 0.022
regulation of transferase activity GO:0051338 263 0.022
regulation of protein localization GO:0032880 231 0.021
dephosphorylation GO:0016311 129 0.021
mitochondrion organization GO:0007005 134 0.021
regulation of membrane potential GO:0042391 192 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
microtubule based process GO:0007017 236 0.021
maintenance of location GO:0051235 89 0.021
organelle localization GO:0051640 179 0.020
rho protein signal transduction GO:0007266 32 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
dna metabolic process GO:0006259 303 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
protein maturation GO:0051604 176 0.020
regulation of cell projection organization GO:0031344 206 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
regulation of neuron differentiation GO:0045664 281 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
peptidyl amino acid modification GO:0018193 336 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
synaptic transmission GO:0007268 329 0.019
skeletal system development GO:0001501 356 0.019
male gamete generation GO:0048232 285 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
negative regulation of molecular function GO:0044092 258 0.019
anion transmembrane transport GO:0098656 71 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
protein catabolic process GO:0030163 221 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
locomotory behavior GO:0007626 195 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
regulation of ras gtpase activity GO:0032318 88 0.018
sensory perception GO:0007600 245 0.018
positive regulation of cell development GO:0010720 237 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
regulation of ion transport GO:0043269 215 0.018
nuclear division GO:0000280 158 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
cytoplasmic transport GO:0016482 234 0.018
organic acid biosynthetic process GO:0016053 86 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
cofactor metabolic process GO:0051186 80 0.018
regulation of cell activation GO:0050865 289 0.018
action potential GO:0001508 78 0.018
protein processing GO:0016485 163 0.018
developmental maturation GO:0021700 193 0.018
cellular homeostasis GO:0019725 240 0.017
leukocyte differentiation GO:0002521 342 0.017
response to organic cyclic compound GO:0014070 198 0.017
regulation of protein kinase activity GO:0045859 232 0.017
neuronal action potential GO:0019228 54 0.017
lipid catabolic process GO:0016042 69 0.017
chromatin organization GO:0006325 206 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
organelle fission GO:0048285 170 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
multicellular organismal signaling GO:0035637 91 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
transmission of nerve impulse GO:0019226 76 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
cytokine production GO:0001816 319 0.017
regulation of kinase activity GO:0043549 249 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
mapk cascade GO:0000165 281 0.016
regulation of anatomical structure size GO:0090066 178 0.016
carboxylic acid transport GO:0046942 100 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
camera type eye development GO:0043010 266 0.016
generation of precursor metabolites and energy GO:0006091 103 0.016
myeloid cell differentiation GO:0030099 233 0.016
protein localization to membrane GO:0072657 108 0.016
regulation of cell cycle GO:0051726 281 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
germ cell development GO:0007281 185 0.015
positive regulation of cell death GO:0010942 224 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
histone modification GO:0016570 159 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
cellular protein complex assembly GO:0043623 116 0.015
neuron death GO:0070997 154 0.015
blood vessel morphogenesis GO:0048514 285 0.015
regulation of secretion GO:0051046 274 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
regulation of secretion by cell GO:1903530 249 0.015
circulatory system process GO:0003013 197 0.015
ossification GO:0001503 216 0.015
cell adhesion GO:0007155 329 0.015
axonogenesis GO:0007409 274 0.015
positive regulation of transferase activity GO:0051347 167 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
regulation of hormone levels GO:0010817 211 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
cellular chemical homeostasis GO:0055082 215 0.015
muscle tissue development GO:0060537 308 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
immune effector process GO:0002252 321 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
cellular response to lipid GO:0071396 145 0.015
regulation of mapk cascade GO:0043408 248 0.015
regulation of lipid metabolic process GO:0019216 118 0.014
protein ubiquitination GO:0016567 171 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
compound eye development GO:0048749 1 0.014
skin development GO:0043588 220 0.014
tube formation GO:0035148 140 0.014
epithelial cell development GO:0002064 159 0.014
response to nutrient levels GO:0031667 109 0.014
lipid modification GO:0030258 65 0.014
sulfur compound metabolic process GO:0006790 100 0.014
protein targeting GO:0006605 143 0.014
striated muscle tissue development GO:0014706 293 0.014
lipid localization GO:0010876 126 0.014
response to extracellular stimulus GO:0009991 127 0.014
muscle cell differentiation GO:0042692 261 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
gland development GO:0048732 330 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
positive regulation of gtp catabolic process GO:0033126 85 0.014
regulation of homeostatic process GO:0032844 182 0.014
chromatin modification GO:0016568 187 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
covalent chromatin modification GO:0016569 163 0.014
t cell activation GO:0042110 289 0.014
response to inorganic substance GO:0010035 96 0.014
response to oxidative stress GO:0006979 123 0.014
endocytosis GO:0006897 168 0.014
alcohol metabolic process GO:0006066 116 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
monocarboxylic acid biosynthetic process GO:0072330 61 0.014
epithelial tube formation GO:0072175 130 0.014
neural tube development GO:0021915 160 0.014
actin filament organization GO:0007015 113 0.014
regulation of gtp catabolic process GO:0033124 113 0.014
anatomical structure homeostasis GO:0060249 145 0.013
translation GO:0006412 93 0.013
plasma membrane organization GO:0007009 90 0.013
regulation of transmembrane transport GO:0034762 128 0.013
sensory organ morphogenesis GO:0090596 242 0.013
response to radiation GO:0009314 165 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
regulation of cytokine production GO:0001817 266 0.013
carbohydrate homeostasis GO:0033500 128 0.013
regulation of cell motility GO:2000145 236 0.013
organic acid catabolic process GO:0016054 51 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
small molecule catabolic process GO:0044282 71 0.013
cell division GO:0051301 120 0.013
glucose homeostasis GO:0042593 128 0.013
regulation of cell migration GO:0030334 219 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of cellular component size GO:0032535 121 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
establishment of organelle localization GO:0051656 122 0.013
fat cell differentiation GO:0045444 160 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
respiratory system development GO:0060541 190 0.013
oocyte construction GO:0007308 2 0.013
cation homeostasis GO:0055080 212 0.013
renal system development GO:0072001 225 0.013
positive regulation of nervous system development GO:0051962 221 0.013
hexose metabolic process GO:0019318 98 0.013
blood circulation GO:0008015 195 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
steroid metabolic process GO:0008202 119 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
cognition GO:0050890 149 0.012
response to light stimulus GO:0009416 135 0.012
cell maturation GO:0048469 127 0.012
regulation of proteolysis GO:0030162 164 0.012
positive regulation of kinase activity GO:0033674 155 0.012
gtp catabolic process GO:0006184 143 0.012
peptide transport GO:0015833 133 0.012
oocyte axis specification GO:0007309 2 0.012
lipid transport GO:0006869 98 0.012
glycoprotein metabolic process GO:0009100 116 0.012
negative regulation of protein modification process GO:0031400 163 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
negative regulation of nervous system development GO:0051961 156 0.012
rhythmic process GO:0048511 174 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
regulation of neuron death GO:1901214 134 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
phospholipid metabolic process GO:0006644 87 0.012
innate immune response GO:0045087 157 0.012
meiotic cell cycle GO:0051321 122 0.012
gtp metabolic process GO:0046039 144 0.012
response to growth factor GO:0070848 198 0.012
neural tube formation GO:0001841 108 0.012
telencephalon development GO:0021537 186 0.012
regulation of neuron projection development GO:0010975 169 0.012
response to lipopolysaccharide GO:0032496 128 0.012
neuron apoptotic process GO:0051402 142 0.012
regionalization GO:0003002 337 0.012
forebrain development GO:0030900 302 0.012
regulation of system process GO:0044057 200 0.012
amide transport GO:0042886 138 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
cellular ion homeostasis GO:0006873 165 0.012
lateral inhibition GO:0046331 1 0.012
actin filament based movement GO:0030048 23 0.012
multicellular organism growth GO:0035264 161 0.012
regulation of translation GO:0006417 71 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
monosaccharide metabolic process GO:0005996 106 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
regulation of t cell activation GO:0050863 170 0.012
regulation of cell cycle process GO:0010564 160 0.012
cell substrate adhesion GO:0031589 130 0.012
lymphocyte proliferation GO:0046651 164 0.012
atp metabolic process GO:0046034 75 0.012
lung development GO:0030324 164 0.012
lymphocyte differentiation GO:0030098 242 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
negative regulation of cell development GO:0010721 169 0.012
response to insulin GO:0032868 100 0.011
wnt signaling pathway GO:0016055 188 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
protein polymerization GO:0051258 57 0.011
mitotic cell cycle GO:0000278 195 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
chemotaxis GO:0006935 247 0.011
spermatid differentiation GO:0048515 115 0.011
response to acid chemical GO:0001101 111 0.011
regulation of actin filament based process GO:0032970 99 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
epithelial cell proliferation GO:0050673 174 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
divalent metal ion transport GO:0070838 172 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
dendrite development GO:0016358 115 0.011
regulation of defense response GO:0031347 233 0.011
regulation of response to wounding GO:1903034 189 0.011
positive regulation of growth GO:0045927 104 0.011
regulation of cell adhesion GO:0030155 154 0.011
tissue homeostasis GO:0001894 115 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
hormone secretion GO:0046879 128 0.011
response to peptide GO:1901652 136 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
spermatid development GO:0007286 108 0.011
heart morphogenesis GO:0003007 178 0.011
tube closure GO:0060606 91 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of endocytosis GO:0030100 69 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
urogenital system development GO:0001655 261 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
establishment of protein localization to organelle GO:0072594 118 0.010
metal ion homeostasis GO:0055065 189 0.010
cellular protein catabolic process GO:0044257 155 0.010
muscle system process GO:0003012 141 0.010
protein oligomerization GO:0051259 67 0.010
peptidyl serine modification GO:0018209 83 0.010
asymmetric stem cell division GO:0098722 3 0.010
coenzyme biosynthetic process GO:0009108 23 0.010
adult behavior GO:0030534 135 0.010
b cell activation GO:0042113 161 0.010
cellular response to peptide GO:1901653 92 0.010
cellularization GO:0007349 1 0.010
negative regulation of immune system process GO:0002683 209 0.010
myeloid cell homeostasis GO:0002262 114 0.010
mrna metabolic process GO:0016071 84 0.010
peptide hormone secretion GO:0030072 109 0.010
kidney development GO:0001822 213 0.010
glucose metabolic process GO:0006006 92 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
ear development GO:0043583 200 0.010
limb development GO:0060173 166 0.010
rab protein signal transduction GO:0032482 1 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
skeletal system morphogenesis GO:0048705 203 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
respiratory tube development GO:0030323 167 0.010

Ralgapa2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.019
musculoskeletal system disease DOID:17 0 0.018
disease of cellular proliferation DOID:14566 0 0.016
immune system disease DOID:2914 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
central nervous system disease DOID:331 0 0.014
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.011