Mus musculus

79 known processes

Cd59b

CD59b antigen

Cd59b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
activation of membrane attack complex GO:0001905 4 0.685
protein activation cascade GO:0072376 19 0.676
negative regulation of complement activation GO:0045916 3 0.553
negative regulation of protein activation cascade GO:2000258 3 0.417
complement activation GO:0006956 16 0.251
humoral immune response GO:0006959 57 0.197
regulation of fibroblast growth factor production GO:0090270 4 0.189
Mouse
immune effector process GO:0002252 321 0.181
cytokine production GO:0001816 319 0.159
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.151
protein processing GO:0016485 163 0.140
regulation of inflammatory response GO:0050727 147 0.117
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.113
Mouse
cytolysis GO:0019835 8 0.112
negative regulation of immune system process GO:0002683 209 0.105
negative regulation of protein processing GO:0010955 79 0.105
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.104
Mouse
activation of immune response GO:0002253 138 0.100
regulation of cytokine production GO:0001817 266 0.097
Mouse
angiogenesis GO:0001525 201 0.092
Mouse
negative regulation of cytokine production GO:0001818 84 0.088
Mouse
regulation of protein processing GO:0070613 96 0.087
regulation of acute inflammatory response GO:0002673 27 0.084
negative regulation of immune effector process GO:0002698 55 0.081
protein maturation GO:0051604 176 0.081
negative regulation of protein maturation GO:1903318 79 0.075
negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948 6 0.068
Mouse
regulation of protein maturation GO:1903317 96 0.060
cellular response to growth factor stimulus GO:0071363 197 0.059
Mouse
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.058
Mouse
acute inflammatory response GO:0002526 41 0.057
tetrapyrrole metabolic process GO:0033013 22 0.052
regulation of protein activation cascade GO:2000257 7 0.050
negative regulation of vasculature development GO:1901343 26 0.046
Mouse
male gamete generation GO:0048232 285 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
negative regulation of angiogenesis GO:0016525 25 0.043
Mouse
transmembrane transport GO:0055085 412 0.043
regulation of cell activation GO:0050865 289 0.043
amine metabolic process GO:0009308 45 0.042
cellular amino acid metabolic process GO:0006520 103 0.040
inorganic ion transmembrane transport GO:0098660 234 0.038
regulation of humoral immune response GO:0002920 22 0.036
cofactor biosynthetic process GO:0051188 41 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
inflammatory response GO:0006954 244 0.035
response to growth factor GO:0070848 198 0.035
Mouse
regulation of intracellular transport GO:0032386 159 0.034
positive regulation of potassium ion transport GO:0043268 3 0.034
cellular lipid metabolic process GO:0044255 323 0.033
regulation of vasculature development GO:1901342 88 0.033
Mouse
cellular ketone metabolic process GO:0042180 84 0.032
regulation of cellular response to growth factor stimulus GO:0090287 82 0.032
Mouse
homeostasis of number of cells GO:0048872 210 0.031
nuclear division GO:0000280 158 0.030
spermatogenesis GO:0007283 284 0.029
regulation of cytolysis GO:0042268 1 0.029
cation transport GO:0006812 399 0.028
positive regulation of cell activation GO:0050867 158 0.028
dna metabolic process GO:0006259 303 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
cofactor metabolic process GO:0051186 80 0.027
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.026
multicellular organismal signaling GO:0035637 91 0.026
fertilization GO:0009566 127 0.026
meiotic cell cycle process GO:1903046 77 0.026
porphyrin containing compound metabolic process GO:0006778 22 0.025
inorganic anion transmembrane transport GO:0098661 29 0.025
transmission of nerve impulse GO:0019226 76 0.025
cytoplasmic transport GO:0016482 234 0.024
sa node cell action potential GO:0086015 4 0.024
multicellular organism growth GO:0035264 161 0.023
myeloid cell differentiation GO:0030099 233 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.023
organic cyclic compound catabolic process GO:1901361 295 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
tetrapyrrole biosynthetic process GO:0033014 16 0.022
iron ion homeostasis GO:0055072 36 0.021
organelle fission GO:0048285 170 0.021
t cell activation GO:0042110 289 0.021
cellular response to molecule of bacterial origin GO:0071219 83 0.021
negative regulation of homeostatic process GO:0032845 71 0.021
regulation of leukocyte proliferation GO:0070663 121 0.020
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.020
response to organic cyclic compound GO:0014070 198 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
steroid metabolic process GO:0008202 119 0.020
mitotic cell cycle process GO:1903047 159 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.019
histone modification GO:0016570 159 0.019
myeloid cell homeostasis GO:0002262 114 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
translation GO:0006412 93 0.019
cation transmembrane transport GO:0098655 266 0.019
regulation of lymphocyte mediated immunity GO:0002706 84 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.019
porphyrin containing compound biosynthetic process GO:0006779 16 0.019
membrane organization GO:0061024 245 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
regulation of body fluid levels GO:0050878 162 0.018
ion transmembrane transport GO:0034220 361 0.017
cellular response to lipid GO:0071396 145 0.017
anion transport GO:0006820 177 0.017
leukocyte mediated cytotoxicity GO:0001909 62 0.017
cellular response to acid chemical GO:0071229 68 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
learning or memory GO:0007611 148 0.017
response to lipopolysaccharide GO:0032496 128 0.017
erythrocyte differentiation GO:0030218 88 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
regulation of organelle organization GO:0033043 289 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
blood circulation GO:0008015 195 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
chromatin modification GO:0016568 187 0.016
regulation of transmembrane transport GO:0034762 128 0.016
action potential GO:0001508 78 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
defense response to other organism GO:0098542 197 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
cognition GO:0050890 149 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
positive regulation of binding GO:0051099 49 0.016
positive regulation of immune effector process GO:0002699 107 0.015
olfactory learning GO:0008355 2 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
regulation of cell cycle GO:0051726 281 0.015
chromatin organization GO:0006325 206 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
response to acid chemical GO:0001101 111 0.015
neuronal action potential GO:0019228 54 0.015
regulation of binding GO:0051098 111 0.015
positive regulation of protein transport GO:0051222 93 0.015
transition metal ion homeostasis GO:0055076 54 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
endomembrane system organization GO:0010256 147 0.015
organ regeneration GO:0031100 2 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
protein ubiquitination GO:0016567 171 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
mitotic cell cycle GO:0000278 195 0.015
t cell differentiation GO:0030217 174 0.015
regulation of response to wounding GO:1903034 189 0.015
cellular amine metabolic process GO:0044106 44 0.014
cardiac muscle cell contraction GO:0086003 7 0.014
divalent inorganic cation transport GO:0072511 178 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of hormone levels GO:0010817 211 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
lipid transport GO:0006869 98 0.014
organic acid biosynthetic process GO:0016053 86 0.014
nucleotide metabolic process GO:0009117 332 0.014
cellular homeostasis GO:0019725 240 0.014
striated muscle tissue development GO:0014706 293 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
cellular hyperosmotic salinity response GO:0071475 0 0.014
regulation of t cell proliferation GO:0042129 92 0.014
response to organonitrogen compound GO:0010243 246 0.014
response to nutrient levels GO:0031667 109 0.014
muscle cell differentiation GO:0042692 261 0.014
cellular ion homeostasis GO:0006873 165 0.013
ear development GO:0043583 200 0.013
tissue homeostasis GO:0001894 115 0.013
covalent chromatin modification GO:0016569 163 0.013
intracellular protein transport GO:0006886 204 0.013
regulation of secretion GO:0051046 274 0.013
microtubule based process GO:0007017 236 0.013
adult behavior GO:0030534 135 0.013
cellular potassium ion transport GO:0071804 43 0.013
aromatic compound catabolic process GO:0019439 286 0.013
purine containing compound metabolic process GO:0072521 311 0.013
heterocycle catabolic process GO:0046700 280 0.013
response to light stimulus GO:0009416 135 0.013
developmental maturation GO:0021700 193 0.013
response to extracellular stimulus GO:0009991 127 0.013
response to peptide hormone GO:0043434 127 0.013
response to starvation GO:0042594 65 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
dephosphorylation GO:0016311 129 0.013
positive regulation of protein modification process GO:0031401 299 0.013
forebrain development GO:0030900 302 0.013
leukocyte differentiation GO:0002521 342 0.013
fatty acid metabolic process GO:0006631 121 0.013
leukocyte activation involved in immune response GO:0002366 126 0.012
metal ion homeostasis GO:0055065 189 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
locomotory behavior GO:0007626 195 0.012
positive regulation of t cell activation GO:0050870 101 0.012
regulation of t cell activation GO:0050863 170 0.012
synaptic transmission GO:0007268 329 0.012
cell type specific apoptotic process GO:0097285 268 0.012
regulation of mapk cascade GO:0043408 248 0.012
calcium ion homeostasis GO:0055074 127 0.012
sensory perception GO:0007600 245 0.012
regulation of membrane potential GO:0042391 192 0.012
plasma membrane organization GO:0007009 90 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
leukocyte homeostasis GO:0001776 79 0.012
metencephalon development GO:0022037 89 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
actin mediated cell contraction GO:0070252 15 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
protein targeting GO:0006605 143 0.011
sterol homeostasis GO:0055092 45 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of ion transport GO:0043269 215 0.011
body morphogenesis GO:0010171 45 0.011
protein alkylation GO:0008213 81 0.011
response to steroid hormone GO:0048545 56 0.011
macromolecule methylation GO:0043414 120 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
potassium ion transmembrane transport GO:0071805 43 0.011
macromolecule catabolic process GO:0009057 281 0.011
stem cell maintenance GO:0019827 130 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
lipid localization GO:0010876 126 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
adaptive immune response GO:0002250 155 0.011
regulation of protein binding GO:0043393 60 0.011
positive regulation of potassium ion transmembrane transporter activity GO:1901018 1 0.011
chloride transmembrane transport GO:1902476 24 0.011
response to peptide GO:1901652 136 0.011
mapk cascade GO:0000165 281 0.011
positive regulation of cytokine production GO:0001819 174 0.010
methylation GO:0032259 134 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
regulation of cell killing GO:0031341 40 0.010
hormone metabolic process GO:0042445 86 0.010
ribonucleotide metabolic process GO:0009259 291 0.010
synapse organization GO:0050808 125 0.010
sodium ion transmembrane transport GO:0035725 49 0.010
negative regulation of neuron death GO:1901215 98 0.010
peptidyl amino acid modification GO:0018193 336 0.010
oocyte axis specification GO:0007309 2 0.010
regulation of transferase activity GO:0051338 263 0.010
cilium morphogenesis GO:0060271 102 0.010
hexose metabolic process GO:0019318 98 0.010
chloride transport GO:0006821 32 0.010
lymphocyte homeostasis GO:0002260 64 0.010

Cd59b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.045
immune system disease DOID:2914 0 0.039
disease of anatomical entity DOID:7 0 0.039
anemia DOID:2355 0 0.039
hematopoietic system disease DOID:74 0 0.039
central nervous system disease DOID:331 0 0.026
nervous system disease DOID:863 0 0.026
inherited metabolic disorder DOID:655 0 0.015
normocytic anemia DOID:720 0 0.011
neurodegenerative disease DOID:1289 0 0.011