Mus musculus

0 known processes

Rab4b

RAB4B, member RAS oncogene family

(Aliases: 1500031G17Rik)

Rab4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 102 0.189
cilium assembly GO:0042384 81 0.176
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.158
regulation of clathrin mediated endocytosis GO:2000369 4 0.152
positive regulation of cellular amine metabolic process GO:0033240 5 0.135
axonogenesis GO:0007409 274 0.131
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.129
amine metabolic process GO:0009308 45 0.092
regulation of cellular ketone metabolic process GO:0010565 66 0.089
regulation of cellular amino acid metabolic process GO:0006521 5 0.088
regulation of ion transport GO:0043269 215 0.086
regulation of cell projection organization GO:0031344 206 0.081
establishment of organelle localization GO:0051656 122 0.081
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.080
cellular amino acid metabolic process GO:0006520 103 0.079
carbohydrate derivative catabolic process GO:1901136 231 0.078
cellular amine metabolic process GO:0044106 44 0.076
regulation of actin nucleation GO:0051125 4 0.073
regulation of intracellular transport GO:0032386 159 0.067
cytoplasmic transport GO:0016482 234 0.066
Mouse
positive regulation of necrotic cell death GO:0010940 1 0.065
regulation of organelle organization GO:0033043 289 0.065
cellular lipid metabolic process GO:0044255 323 0.060
macromolecule catabolic process GO:0009057 281 0.059
glycosyl compound metabolic process GO:1901657 246 0.059
negative regulation of organelle organization GO:0010639 90 0.059
sequestering of calcium ion GO:0051208 18 0.059
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.058
negative regulation of cellular component organization GO:0051129 194 0.058
arp2 3 complex mediated actin nucleation GO:0034314 3 0.058
ion transmembrane transport GO:0034220 361 0.057
negative regulation of neuron death GO:1901215 98 0.057
regulation of cellular component biogenesis GO:0044087 181 0.056
protein localization to organelle GO:0033365 185 0.056
regulation of establishment of protein localization GO:0070201 181 0.055
cellular ketone metabolic process GO:0042180 84 0.055
actin polymerization or depolymerization GO:0008154 54 0.053
regulation of neuron death GO:1901214 134 0.053
regulation of cellular amine metabolic process GO:0033238 20 0.052
retina development in camera type eye GO:0060041 119 0.051
divalent inorganic cation transport GO:0072511 178 0.051
positive regulation of programmed cell death GO:0043068 218 0.050
cellular response to cytokine stimulus GO:0071345 189 0.049
regulation of cytoplasmic transport GO:1903649 112 0.049
actin cytoskeleton organization GO:0030036 220 0.048
cation transport GO:0006812 399 0.047
camera type eye development GO:0043010 266 0.046
positive regulation of actin nucleation GO:0051127 3 0.045
regulation of calcium ion transport into cytosol GO:0010522 31 0.045
protein complex disassembly GO:0043241 40 0.043
organelle fission GO:0048285 170 0.041
actin filament polymerization GO:0030041 44 0.041
negative regulation of vesicle fusion GO:0031339 1 0.041
cell type specific apoptotic process GO:0097285 268 0.040
intracellular protein transport GO:0006886 204 0.039
apoptotic signaling pathway GO:0097190 306 0.039
t cell proliferation GO:0042098 120 0.039
organelle localization GO:0051640 179 0.039
release of sequestered calcium ion into cytosol GO:0051209 42 0.038
regulation of protein localization GO:0032880 231 0.038
cellular ion homeostasis GO:0006873 165 0.037
regulation of vesicle mediated transport GO:0060627 139 0.037
Mouse
tissue homeostasis GO:0001894 115 0.037
neuron death GO:0070997 154 0.036
epidermis development GO:0008544 187 0.036
nucleocytoplasmic transport GO:0006913 139 0.036
organelle assembly GO:0070925 177 0.036
peptidyl amino acid modification GO:0018193 336 0.036
synaptic transmission GO:0007268 329 0.036
regulation of metal ion transport GO:0010959 106 0.035
regulation of actin polymerization or depolymerization GO:0008064 45 0.035
neuron apoptotic process GO:0051402 142 0.035
leukocyte proliferation GO:0070661 172 0.035
chromatin modification GO:0016568 187 0.034
regulation of cell cycle GO:0051726 281 0.034
purine containing compound metabolic process GO:0072521 311 0.034
regulation of protein transport GO:0051223 163 0.034
nuclear import GO:0051170 95 0.034
hematopoietic progenitor cell differentiation GO:0002244 143 0.033
protein localization to membrane GO:0072657 108 0.033
response to growth factor GO:0070848 198 0.032
Mouse
endocytosis GO:0006897 168 0.032
Mouse
sequestering of metal ion GO:0051238 19 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
regulation of cell activation GO:0050865 289 0.031
positive regulation of cell death GO:0010942 224 0.031
nucleotide metabolic process GO:0009117 332 0.031
rac protein signal transduction GO:0016601 13 0.031
regulation of actin filament length GO:0030832 45 0.031
positive regulation of organelle organization GO:0010638 128 0.031
regulation of nucleotide metabolic process GO:0006140 169 0.031
blood circulation GO:0008015 195 0.031
activation of immune response GO:0002253 138 0.031
regulation of protein maturation GO:1903317 96 0.031
histone modification GO:0016570 159 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
dephosphorylation GO:0016311 129 0.030
divalent metal ion transport GO:0070838 172 0.030
cytosolic calcium ion transport GO:0060401 48 0.030
response to organonitrogen compound GO:0010243 246 0.030
actin filament organization GO:0007015 113 0.030
anatomical structure homeostasis GO:0060249 145 0.030
calcium ion transport GO:0006816 159 0.029
negative regulation of molecular function GO:0044092 258 0.029
vesicle localization GO:0051648 86 0.029
uropod organization GO:0032796 2 0.028
regulation of kinase activity GO:0043549 249 0.028
peptidyl tyrosine phosphorylation GO:0018108 143 0.028
metal ion homeostasis GO:0055065 189 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
glycerolipid metabolic process GO:0046486 122 0.028
establishment of protein localization to organelle GO:0072594 118 0.028
positive regulation of actin filament polymerization GO:0030838 26 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
meiotic cell cycle GO:0051321 122 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
response to radiation GO:0009314 165 0.026
membrane organization GO:0061024 245 0.026
negative regulation of neuron apoptotic process GO:0043524 92 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
cell division GO:0051301 120 0.026
cellular chemical homeostasis GO:0055082 215 0.025
aromatic compound catabolic process GO:0019439 286 0.025
locomotory behavior GO:0007626 195 0.025
regulation of protein complex disassembly GO:0043244 28 0.025
meiotic nuclear division GO:0007126 115 0.025
regulation of endocytosis GO:0030100 69 0.025
Mouse
regulation of cell growth GO:0001558 91 0.025
microtubule based process GO:0007017 236 0.025
single organism nuclear import GO:1902593 95 0.025
protein maturation GO:0051604 176 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.024
positive regulation of cell activation GO:0050867 158 0.024
maintenance of location GO:0051235 89 0.024
carbohydrate metabolic process GO:0005975 230 0.024
positive regulation of cellular component biogenesis GO:0044089 94 0.024
immune response regulating signaling pathway GO:0002764 125 0.024
negative regulation of cytoskeleton organization GO:0051494 36 0.024
male gamete generation GO:0048232 285 0.024
protein import GO:0017038 101 0.023
nuclear transport GO:0051169 139 0.023
peptidyl serine phosphorylation GO:0018105 74 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
sensory organ morphogenesis GO:0090596 242 0.023
negative regulation of protein complex disassembly GO:0043242 22 0.023
cell fate commitment GO:0045165 210 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
regulation of secretion by cell GO:1903530 249 0.022
regulation of proteolysis GO:0030162 164 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
regulation of t cell activation GO:0050863 170 0.022
regulation of cellular component size GO:0032535 121 0.022
alcohol metabolic process GO:0006066 116 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
calcium ion transport into cytosol GO:0060402 48 0.022
cation transmembrane transport GO:0098655 266 0.022
mapk cascade GO:0000165 281 0.022
positive regulation of protein modification process GO:0031401 299 0.022
cell adhesion GO:0007155 329 0.022
carbohydrate homeostasis GO:0033500 128 0.021
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
positive regulation of intracellular transport GO:0032388 70 0.021
positive regulation of t cell activation GO:0050870 101 0.021
homeostasis of number of cells GO:0048872 210 0.021
establishment of protein localization to membrane GO:0090150 54 0.021
regulation of homeostatic process GO:0032844 182 0.021
adult behavior GO:0030534 135 0.021
regulation of lamellipodium assembly GO:0010591 3 0.021
meiotic cell cycle process GO:1903046 77 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
negative regulation of nervous system development GO:0051961 156 0.021
asymmetric neuroblast division GO:0055059 1 0.021
cellular protein complex disassembly GO:0043624 36 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
positive regulation of transferase activity GO:0051347 167 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
protein targeting GO:0006605 143 0.020
vesicle fusion GO:0006906 16 0.020
spermatogenesis GO:0007283 284 0.020
protein catabolic process GO:0030163 221 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
protein processing GO:0016485 163 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
skin development GO:0043588 220 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
cerebral cortex radially oriented cell migration GO:0021799 31 0.019
dna metabolic process GO:0006259 303 0.019
cell communication by chemical coupling GO:0010643 2 0.019
positive regulation of cell motility GO:2000147 116 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
regulation of neuron differentiation GO:0045664 281 0.019
metencephalon development GO:0022037 89 0.019
lytic vacuole organization GO:0080171 21 0.019
t cell activation GO:0042110 289 0.019
response to organic cyclic compound GO:0014070 198 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
phospholipid metabolic process GO:0006644 87 0.019
negative regulation of cell development GO:0010721 169 0.018
regulation of transferase activity GO:0051338 263 0.018
peptide hormone secretion GO:0030072 109 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
response to peptide GO:1901652 136 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
cellular response to lipid GO:0071396 145 0.018
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.018
muscle tissue development GO:0060537 308 0.018
peptidyl threonine phosphorylation GO:0018107 31 0.017
cation homeostasis GO:0055080 212 0.017
cellular protein complex assembly GO:0043623 116 0.017
negative regulation of homeostatic process GO:0032845 71 0.017
intra golgi vesicle mediated transport GO:0006891 1 0.017
nitrogen compound transport GO:0071705 271 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
transmembrane transport GO:0055085 412 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
cellular response to hexose stimulus GO:0071331 47 0.017
regulation of mapk cascade GO:0043408 248 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
small molecule catabolic process GO:0044282 71 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.016
establishment of vesicle localization GO:0051650 81 0.016
nuclear division GO:0000280 158 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
calcium ion homeostasis GO:0055074 127 0.016
positive regulation of leukocyte proliferation GO:0070665 73 0.016
response to monosaccharide GO:0034284 67 0.016
leukocyte homeostasis GO:0001776 79 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.016
germ cell development GO:0007281 185 0.016
sensory system development GO:0048880 3 0.016
regulation of actin filament polymerization GO:0030833 38 0.016
heart process GO:0003015 94 0.016
regulation of neuron apoptotic process GO:0043523 122 0.016
regulation of feeding behavior GO:0060259 3 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
cellular homeostasis GO:0019725 240 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
regulation of hormone levels GO:0010817 211 0.015
cytosolic calcium ion homeostasis GO:0051480 70 0.015
negative regulation of intracellular transport GO:0032387 38 0.015
organophosphate catabolic process GO:0046434 232 0.015
regulation of anatomical structure size GO:0090066 178 0.015
amide transport GO:0042886 138 0.015
regulation of protein import into nucleus GO:0042306 52 0.015
nucleoside catabolic process GO:0009164 206 0.015
establishment of protein localization to mitochondrion GO:0072655 11 0.015
regulation of transmembrane transport GO:0034762 128 0.015
positive regulation of nervous system development GO:0051962 221 0.015
peptidyl serine modification GO:0018209 83 0.015
plasma membrane organization GO:0007009 90 0.015
rho protein signal transduction GO:0007266 32 0.015
positive regulation of cell development GO:0010720 237 0.015
covalent chromatin modification GO:0016569 163 0.015
regulation of intracellular protein transport GO:0033157 82 0.014
hormone secretion GO:0046879 128 0.014
regulation of calcium ion transport GO:0051924 69 0.014
protein import into nucleus GO:0006606 95 0.014
regulation of microtubule based process GO:0032886 52 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
hindbrain development GO:0030902 128 0.014
necrotic cell death GO:0070265 30 0.014
cellular protein catabolic process GO:0044257 155 0.014
smoothened signaling pathway GO:0007224 105 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
steroid metabolic process GO:0008202 119 0.014
response to inorganic substance GO:0010035 96 0.014
regulation of rho protein signal transduction GO:0035023 71 0.014
regulation of blood pressure GO:0008217 93 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
cellular response to glucose stimulus GO:0071333 45 0.014
innate immune response GO:0045087 157 0.014
regulation of cytokine production GO:0001817 266 0.014
regulation of secretion GO:0051046 274 0.013
peptide secretion GO:0002790 114 0.013
negative regulation of gene silencing GO:0060969 2 0.013
regulation of protein heterodimerization activity GO:0043497 2 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
nerve growth factor signaling pathway GO:0038180 3 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
mitochondrion organization GO:0007005 134 0.013
ear development GO:0043583 200 0.013
glucose homeostasis GO:0042593 128 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
golgi to endosome transport GO:0006895 3 0.013
Mouse
phosphatidic acid metabolic process GO:0046473 2 0.013
protein polymerization GO:0051258 57 0.013
hair cycle GO:0042633 90 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
regulation of protein processing GO:0070613 96 0.013
histone phosphorylation GO:0016572 9 0.013
regulation of protein depolymerization GO:1901879 26 0.013
positive regulation of mammary gland involution GO:1903521 4 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
retina morphogenesis in camera type eye GO:0060042 45 0.013
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 4 0.013
regulation of heart contraction GO:0008016 77 0.013
ras protein signal transduction GO:0007265 77 0.013
lateral line system development GO:0048925 1 0.012
sensory perception GO:0007600 245 0.012
regulation of hydrolase activity GO:0051336 246 0.012
negative regulation of defense response GO:0031348 77 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
leukocyte differentiation GO:0002521 342 0.012
skeletal myofibril assembly GO:0014866 4 0.012
spermatid differentiation GO:0048515 115 0.012
dendritic spine organization GO:0097061 26 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
positive regulation of ion transport GO:0043270 65 0.012
response to acid chemical GO:0001101 111 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
cholesterol storage GO:0010878 4 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
cell chemotaxis GO:0060326 81 0.012
negative regulation of chromatin silencing GO:0031936 1 0.012
regulation of response to drug GO:2001023 2 0.012
regulation of chromatin silencing GO:0031935 2 0.012
cognition GO:0050890 149 0.012
regulation of glucose metabolic process GO:0010906 60 0.012
protein localization to nucleus GO:0034504 121 0.012
regulation of neuron projection development GO:0010975 169 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
negative regulation of proteolysis GO:0045861 74 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
positive regulation of lamellipodium organization GO:1902745 3 0.012
response to osmotic stress GO:0006970 21 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
regulation of ion transmembrane transport GO:0034765 119 0.011
dendrite development GO:0016358 115 0.011
receptor mediated endocytosis GO:0006898 51 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
negative regulation of pancreatic juice secretion GO:0090188 3 0.011
myeloid cell differentiation GO:0030099 233 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
macromolecular complex disassembly GO:0032984 43 0.011
positive regulation of cytoskeleton organization GO:0051495 49 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of cell migration GO:0030334 219 0.011
extracellular matrix organization GO:0030198 147 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
skeletal system development GO:0001501 356 0.011
dendritic spine maintenance GO:0097062 4 0.011
endomembrane system organization GO:0010256 147 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
positive regulation of protein transport GO:0051222 93 0.011
spermatid development GO:0007286 108 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
cellular response to topologically incorrect protein GO:0035967 25 0.011
mitotic cytokinesis GO:0000281 4 0.011
neuron projection guidance GO:0097485 141 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
molting cycle GO:0042303 90 0.011
positive regulation of kinase activity GO:0033674 155 0.010
actin filament depolymerization GO:0030042 15 0.010
positive regulation of t cell proliferation GO:0042102 52 0.010
triglyceride biosynthetic process GO:0019432 17 0.010
negative regulation of dna replication GO:0008156 4 0.010
negative regulation of binding GO:0051100 39 0.010
mitotic cell cycle GO:0000278 195 0.010
glycoprotein metabolic process GO:0009100 116 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.010
regulation of microtubule cytoskeleton organization GO:0070507 37 0.010
striated muscle tissue development GO:0014706 293 0.010
exocytosis GO:0006887 121 0.010
ribonucleotide metabolic process GO:0009259 291 0.010

Rab4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.039
inherited metabolic disorder DOID:655 0 0.039
central nervous system disease DOID:331 0 0.024
disease of anatomical entity DOID:7 0 0.024
neurodegenerative disease DOID:1289 0 0.024
nervous system disease DOID:863 0 0.024
immune system disease DOID:2914 0 0.019
disease of mental health DOID:150 0 0.016
hematopoietic system disease DOID:74 0 0.013
dementia DOID:1307 0 0.011
cognitive disorder DOID:1561 0 0.011