Mus musculus

22 known processes

Rab4a

RAB4A, member RAS oncogene family

(Aliases: Rab4,AI848268)

Rab4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.089
cellular amine metabolic process GO:0044106 44 0.079
regulation of cellular amino acid metabolic process GO:0006521 5 0.077
cellular amino acid metabolic process GO:0006520 103 0.076
ubiquitin dependent protein catabolic process GO:0006511 129 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.063
regulation of protein kinase activity GO:0045859 232 0.062
protein modification by small protein conjugation or removal GO:0070647 207 0.058
positive regulation of cellular amine metabolic process GO:0033240 5 0.053
regulation of cellular ketone metabolic process GO:0010565 66 0.050
regulation of cellular amine metabolic process GO:0033238 20 0.050
amine metabolic process GO:0009308 45 0.049
cellular lipid metabolic process GO:0044255 323 0.049
negative regulation of molecular function GO:0044092 258 0.049
nucleoside phosphate metabolic process GO:0006753 338 0.047
Human Rat
oxidation reduction process GO:0055114 342 0.047
modification dependent protein catabolic process GO:0019941 133 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.043
Human Rat
regulation of cytokine production GO:0001817 266 0.042
cellular protein catabolic process GO:0044257 155 0.041
purine nucleotide metabolic process GO:0006163 302 0.041
Human Rat
ribonucleotide metabolic process GO:0009259 291 0.041
Human Rat
kidney development GO:0001822 213 0.040
regulation of organelle organization GO:0033043 289 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
Human Rat
regulation of cell cycle GO:0051726 281 0.038
cation transport GO:0006812 399 0.037
regulation of ion transport GO:0043269 215 0.036
regulation of transferase activity GO:0051338 263 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
nitrogen compound transport GO:0071705 271 0.035
cation homeostasis GO:0055080 212 0.034
response to organonitrogen compound GO:0010243 246 0.034
protein modification by small protein conjugation GO:0032446 187 0.033
nucleotide metabolic process GO:0009117 332 0.033
Human Rat
urogenital system development GO:0001655 261 0.033
actin cytoskeleton organization GO:0030036 220 0.033
metal ion homeostasis GO:0055065 189 0.032
macromolecule catabolic process GO:0009057 281 0.032
purine containing compound metabolic process GO:0072521 311 0.032
Human Rat
regulation of kinase activity GO:0043549 249 0.032
response to inorganic substance GO:0010035 96 0.032
cytokine production GO:0001816 319 0.032
protein localization to nucleus GO:0034504 121 0.031
synaptic transmission GO:0007268 329 0.031
positive regulation of apoptotic process GO:0043065 217 0.031
nucleoside metabolic process GO:0009116 246 0.030
Human Rat
lateral inhibition GO:0046331 1 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
ras protein signal transduction GO:0007265 77 0.030
Rat
protein catabolic process GO:0030163 221 0.030
epithelial tube morphogenesis GO:0060562 303 0.029
ion transmembrane transport GO:0034220 361 0.029
regulation of protein localization GO:0032880 231 0.029
peptidyl amino acid modification GO:0018193 336 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
positive regulation of cell death GO:0010942 224 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
ribonucleoside metabolic process GO:0009119 245 0.027
Human Rat
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
sensory organ morphogenesis GO:0090596 242 0.027
protein ubiquitination GO:0016567 171 0.026
positive regulation of programmed cell death GO:0043068 218 0.026
regulation of membrane potential GO:0042391 192 0.026
cell type specific apoptotic process GO:0097285 268 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
g protein coupled receptor signaling pathway GO:0007186 243 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
protein localization to organelle GO:0033365 185 0.025
camera type eye development GO:0043010 266 0.025
regulation of secretion by cell GO:1903530 249 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
Human Rat
small gtpase mediated signal transduction GO:0007264 97 0.025
Rat
response to radiation GO:0009314 165 0.025
embryonic epithelial tube formation GO:0001838 130 0.025
mitotic cell cycle GO:0000278 195 0.025
inorganic cation transmembrane transport GO:0098662 207 0.024
cation transmembrane transport GO:0098655 266 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.023
calcium ion homeostasis GO:0055074 127 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
Human Rat
renal system development GO:0072001 225 0.023
cellular chemical homeostasis GO:0055082 215 0.023
regulation of cell motility GO:2000145 236 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
Human Rat
sulfur compound metabolic process GO:0006790 100 0.023
epithelial tube formation GO:0072175 130 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
negative regulation of protein modification process GO:0031400 163 0.022
chromatin modification GO:0016568 187 0.022
myeloid cell differentiation GO:0030099 233 0.022
apoptotic signaling pathway GO:0097190 306 0.022
compound eye development GO:0048749 1 0.022
wnt signaling pathway GO:0016055 188 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
regulation of cellular catabolic process GO:0031329 242 0.021
Rat
divalent inorganic cation homeostasis GO:0072507 138 0.021
intracellular protein transport GO:0006886 204 0.021
regulation of intracellular transport GO:0032386 159 0.021
regulation of secretion GO:0051046 274 0.021
regulation of cell migration GO:0030334 219 0.021
vesicle localization GO:0051648 86 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
Rat
cellular ion homeostasis GO:0006873 165 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.021
aromatic compound catabolic process GO:0019439 286 0.021
Human Rat
negative regulation of cellular component organization GO:0051129 194 0.021
negative regulation of transferase activity GO:0051348 85 0.020
establishment of vesicle localization GO:0051650 81 0.020
positive regulation of transferase activity GO:0051347 167 0.020
monosaccharide metabolic process GO:0005996 106 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
Human Rat
reactive oxygen species metabolic process GO:0072593 84 0.020
mapk cascade GO:0000165 281 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
positive regulation of protein modification process GO:0031401 299 0.020
negative regulation of kinase activity GO:0033673 81 0.020
circulatory system process GO:0003013 197 0.020
striated muscle contraction GO:0006941 45 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
organelle localization GO:0051640 179 0.020
lipid biosynthetic process GO:0008610 179 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
glycosyl compound catabolic process GO:1901658 206 0.019
Human Rat
regulation of cell activation GO:0050865 289 0.019
exocytosis GO:0006887 121 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
Mouse
fat cell differentiation GO:0045444 160 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
Human Rat
regulation of proteolysis GO:0030162 164 0.019
membrane organization GO:0061024 245 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
gland development GO:0048732 330 0.018
axonogenesis GO:0007409 274 0.018
positive regulation of kinase activity GO:0033674 155 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
carbohydrate metabolic process GO:0005975 230 0.018
response to extracellular stimulus GO:0009991 127 0.018
regulation of exocytosis GO:0017157 61 0.018
chromatin organization GO:0006325 206 0.018
extracellular structure organization GO:0043062 148 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
Human Rat
ribonucleotide catabolic process GO:0009261 208 0.017
Human Rat
microtubule based process GO:0007017 236 0.017
positive regulation of cell development GO:0010720 237 0.017
spermatogenesis GO:0007283 284 0.017
regulation of transmembrane transport GO:0034762 128 0.017
cellular protein complex assembly GO:0043623 116 0.017
cellular homeostasis GO:0019725 240 0.017
response to light stimulus GO:0009416 135 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
muscle contraction GO:0006936 101 0.017
positive regulation of ion transport GO:0043270 65 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
sensory system development GO:0048880 3 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
organelle assembly GO:0070925 177 0.016
carboxylic acid transport GO:0046942 100 0.016
organic acid biosynthetic process GO:0016053 86 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
tube formation GO:0035148 140 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
regulation of neuron death GO:1901214 134 0.016
regulation of hormone levels GO:0010817 211 0.016
wound healing GO:0042060 157 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
Human Rat
microtubule cytoskeleton organization GO:0000226 157 0.016
small molecule biosynthetic process GO:0044283 132 0.016
regulation of cell projection organization GO:0031344 206 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
rhythmic process GO:0048511 174 0.015
negative regulation of cytokine production GO:0001818 84 0.015
anion transport GO:0006820 177 0.015
organophosphate catabolic process GO:0046434 232 0.015
Human Rat
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
endomembrane system organization GO:0010256 147 0.015
cell maturation GO:0048469 127 0.015
blood circulation GO:0008015 195 0.015
regulation of cellular response to stress GO:0080135 159 0.015
regulation of mapk cascade GO:0043408 248 0.015
cytoplasmic transport GO:0016482 234 0.015
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
epidermis development GO:0008544 187 0.015
immune effector process GO:0002252 321 0.015
fatty acid metabolic process GO:0006631 121 0.015
tube closure GO:0060606 91 0.015
protein localization to membrane GO:0072657 108 0.015
regulation of homeostatic process GO:0032844 182 0.015
purine containing compound biosynthetic process GO:0072522 70 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
neuronal action potential GO:0019228 54 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
regulation of multi organism process GO:0043900 111 0.015
muscle system process GO:0003012 141 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
generation of precursor metabolites and energy GO:0006091 103 0.014
regulation of protein transport GO:0051223 163 0.014
dephosphorylation GO:0016311 129 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
Human Rat
second messenger mediated signaling GO:0019932 73 0.014
muscle tissue development GO:0060537 308 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
histone modification GO:0016570 159 0.014
regulation of map kinase activity GO:0043405 120 0.014
neuron apoptotic process GO:0051402 142 0.014
maintenance of location GO:0051235 89 0.014
male gamete generation GO:0048232 285 0.014
organic hydroxy compound transport GO:0015850 93 0.014
regulation of hydrolase activity GO:0051336 246 0.014
Rat
forebrain development GO:0030900 302 0.014
regulation of protein catabolic process GO:0042176 108 0.014
regulation of protein localization to nucleus GO:1900180 60 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
neural tube development GO:0021915 160 0.014
dna metabolic process GO:0006259 303 0.014
skeletal system development GO:0001501 356 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
vesicle organization GO:0016050 60 0.014
inflammatory response GO:0006954 244 0.014
positive regulation of cell cycle GO:0045787 92 0.014
calcium ion transport GO:0006816 159 0.014
regulation of wnt signaling pathway GO:0030111 123 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
Human Rat
regulation of intracellular protein transport GO:0033157 82 0.013
response to nutrient levels GO:0031667 109 0.013
nucleoside catabolic process GO:0009164 206 0.013
Human Rat
spermatid differentiation GO:0048515 115 0.013
regulation of system process GO:0044057 200 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
neuromuscular process GO:0050905 99 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
organic anion transport GO:0015711 137 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
sequestering of metal ion GO:0051238 19 0.013
interleukin 8 production GO:0032637 4 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
Human Rat
nucleoside phosphate catabolic process GO:1901292 222 0.013
Human Rat
neuron neuron synaptic transmission GO:0007270 69 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
cardiac muscle contraction GO:0060048 32 0.013
localization within membrane GO:0051668 4 0.013
substantia nigra development GO:0021762 2 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
sensory perception GO:0007600 245 0.013
regulation of defense response GO:0031347 233 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
neurotransmitter secretion GO:0007269 62 0.012
positive regulation of organelle organization GO:0010638 128 0.012
lateral line system development GO:0048925 1 0.012
sodium ion transport GO:0006814 73 0.012
hexose metabolic process GO:0019318 98 0.012
synaptic vesicle transport GO:0048489 57 0.012
muscle cell differentiation GO:0042692 261 0.012
transmission of nerve impulse GO:0019226 76 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
Rat
ribonucleotide biosynthetic process GO:0009260 59 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
Rat
neuron death GO:0070997 154 0.012
divalent inorganic cation transport GO:0072511 178 0.012
skin development GO:0043588 220 0.012
cofactor metabolic process GO:0051186 80 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
endocytosis GO:0006897 168 0.012
developmental maturation GO:0021700 193 0.012
locomotory behavior GO:0007626 195 0.012
regulation of neuron differentiation GO:0045664 281 0.012
antimicrobial peptide production GO:0002775 2 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
Rat
cellular response to external stimulus GO:0071496 88 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
Rat
transmembrane transport GO:0055085 412 0.012
cell substrate adhesion GO:0031589 130 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
sequestering of calcium ion GO:0051208 18 0.012
neural tube formation GO:0001841 108 0.012
cellular response to starvation GO:0009267 57 0.012
t cell activation GO:0042110 289 0.012
positive regulation of cell motility GO:2000147 116 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
protein modification by small protein removal GO:0070646 21 0.011
ear development GO:0043583 200 0.011
organic acid transport GO:0015849 101 0.011
action potential GO:0001508 78 0.011
connective tissue development GO:0061448 179 0.011
synaptic vesicle localization GO:0097479 59 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
cellular protein complex disassembly GO:0043624 36 0.011
organelle fission GO:0048285 170 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
purine nucleotide biosynthetic process GO:0006164 65 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
Human Rat
response to acid chemical GO:0001101 111 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
homeostasis of number of cells GO:0048872 210 0.011
cell adhesion GO:0007155 329 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
cell fate commitment GO:0045165 210 0.011
regulation of binding GO:0051098 111 0.011
myeloid cell homeostasis GO:0002262 114 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
nephron development GO:0072006 109 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
retina development in camera type eye GO:0060041 119 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
chemokine production GO:0032602 34 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
synaptic transmission glutamatergic GO:0035249 36 0.011
innate immune response GO:0045087 157 0.011
response to metal ion GO:0010038 47 0.011
respiratory system development GO:0060541 190 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.010
Human Rat
central nervous system neuron differentiation GO:0021953 162 0.010
asymmetric stem cell division GO:0098722 3 0.010
mitochondrion organization GO:0007005 134 0.010
rho protein signal transduction GO:0007266 32 0.010
adult behavior GO:0030534 135 0.010
negative regulation of nervous system development GO:0051961 156 0.010
negative regulation of immune system process GO:0002683 209 0.010
protein oligomerization GO:0051259 67 0.010
regulation of neurotransmitter transport GO:0051588 35 0.010
nuclear transport GO:0051169 139 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010
negative regulation of neuron death GO:1901215 98 0.010
mechanoreceptor differentiation GO:0042490 67 0.010
glucose homeostasis GO:0042593 128 0.010
striated muscle tissue development GO:0014706 293 0.010
germ cell development GO:0007281 185 0.010
neural tube closure GO:0001843 90 0.010
cell division GO:0051301 120 0.010
male sex differentiation GO:0046661 109 0.010
alpha amino acid metabolic process GO:1901605 59 0.010
heterocycle catabolic process GO:0046700 280 0.010
Human Rat
regulation of actin filament based process GO:0032970 99 0.010
cellular response to nutrient levels GO:0031669 64 0.010
tissue homeostasis GO:0001894 115 0.010
ketone catabolic process GO:0042182 3 0.010
hormone secretion GO:0046879 128 0.010
divalent metal ion transport GO:0070838 172 0.010

Rab4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.021
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.014
neurodegenerative disease DOID:1289 0 0.010