Mus musculus

0 known processes

Heatr6

HEAT repeat containing 6

(Aliases: 2700008B19Rik,BB135312,FLJ22087,BB249351)

Heatr6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.084
cellular amino acid metabolic process GO:0006520 103 0.072
covalent chromatin modification GO:0016569 163 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.061
regulation of cellular amine metabolic process GO:0033238 20 0.055
cellular amine metabolic process GO:0044106 44 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.054
amine metabolic process GO:0009308 45 0.051
cellular ketone metabolic process GO:0042180 84 0.048
methylation GO:0032259 134 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
chromatin organization GO:0006325 206 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
ras protein signal transduction GO:0007265 77 0.043
myeloid cell differentiation GO:0030099 233 0.042
chromatin modification GO:0016568 187 0.041
histone modification GO:0016570 159 0.040
peptidyl amino acid modification GO:0018193 336 0.039
aromatic compound catabolic process GO:0019439 286 0.036
compound eye development GO:0048749 1 0.034
small gtpase mediated signal transduction GO:0007264 97 0.034
regulation of cell cycle GO:0051726 281 0.034
heterocycle catabolic process GO:0046700 280 0.032
cellular response to dna damage stimulus GO:0006974 207 0.032
organic cyclic compound catabolic process GO:1901361 295 0.031
negative regulation of protein metabolic process GO:0051248 282 0.030
histone methylation GO:0016571 71 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
negative regulation of cellular component organization GO:0051129 194 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
dna repair GO:0006281 107 0.028
cytoplasmic transport GO:0016482 234 0.027
purine containing compound catabolic process GO:0072523 213 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
macromolecule catabolic process GO:0009057 281 0.026
negative regulation of cell proliferation GO:0008285 296 0.025
immune effector process GO:0002252 321 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
regulation of cell cycle process GO:0010564 160 0.025
protein maturation GO:0051604 176 0.024
peptidyl lysine modification GO:0018205 77 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
nucleotide catabolic process GO:0009166 217 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
nuclear division GO:0000280 158 0.024
regulation of proteolysis GO:0030162 164 0.024
regionalization GO:0003002 337 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
protein alkylation GO:0008213 81 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
macromolecule methylation GO:0043414 120 0.023
regulation of organelle organization GO:0033043 289 0.022
intracellular protein transport GO:0006886 204 0.022
leukocyte differentiation GO:0002521 342 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
organophosphate catabolic process GO:0046434 232 0.021
response to organonitrogen compound GO:0010243 246 0.021
nucleotide metabolic process GO:0009117 332 0.021
positive regulation of protein modification process GO:0031401 299 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
digestive system development GO:0055123 200 0.021
protein processing GO:0016485 163 0.021
cell type specific apoptotic process GO:0097285 268 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
spermatogenesis GO:0007283 284 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
negative regulation of organelle organization GO:0010639 90 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
histone lysine methylation GO:0034968 50 0.020
negative regulation of protein modification process GO:0031400 163 0.020
regulation of cellular response to stress GO:0080135 159 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
purine containing compound metabolic process GO:0072521 311 0.020
cytokine production GO:0001816 319 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
regulation of protein localization GO:0032880 231 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
regulation of kinase activity GO:0043549 249 0.019
regulation of chromosome organization GO:0033044 83 0.019
stem cell maintenance GO:0019827 130 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
lateral inhibition GO:0046331 1 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
protein catabolic process GO:0030163 221 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
regulation of hydrolase activity GO:0051336 246 0.019
mitotic cell cycle process GO:1903047 159 0.019
lymphocyte differentiation GO:0030098 242 0.019
nitrogen compound transport GO:0071705 271 0.018
male gamete generation GO:0048232 285 0.018
rho protein signal transduction GO:0007266 32 0.018
gland development GO:0048732 330 0.018
negative regulation of cell cycle GO:0045786 123 0.018
mitotic cell cycle GO:0000278 195 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of defense response GO:0031347 233 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
skeletal system development GO:0001501 356 0.018
carbohydrate metabolic process GO:0005975 230 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
regulation of chromatin modification GO:1903308 57 0.017
mapk cascade GO:0000165 281 0.017
endocytosis GO:0006897 168 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
t cell activation GO:0042110 289 0.017
regulation of secretion GO:0051046 274 0.017
regulation of mapk cascade GO:0043408 248 0.017
innate immune response GO:0045087 157 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
cell fate commitment GO:0045165 210 0.017
regulation of protein processing GO:0070613 96 0.017
protein methylation GO:0006479 81 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
protein localization to organelle GO:0033365 185 0.016
nucleoside metabolic process GO:0009116 246 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.016
negative regulation of nervous system development GO:0051961 156 0.016
regulation of cytokine production GO:0001817 266 0.016
organelle assembly GO:0070925 177 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
maintenance of location GO:0051235 89 0.016
anatomical structure homeostasis GO:0060249 145 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
lipid localization GO:0010876 126 0.016
mitochondrion organization GO:0007005 134 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
stem cell differentiation GO:0048863 268 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
response to peptide GO:1901652 136 0.016
multicellular organism growth GO:0035264 161 0.016
germ cell development GO:0007281 185 0.015
negative regulation of immune system process GO:0002683 209 0.015
protein targeting GO:0006605 143 0.015
regulation of transferase activity GO:0051338 263 0.015
positive regulation of organelle organization GO:0010638 128 0.015
regulation of secretion by cell GO:1903530 249 0.015
nucleoside catabolic process GO:0009164 206 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
regulation of protein kinase activity GO:0045859 232 0.015
cation transmembrane transport GO:0098655 266 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
mrna metabolic process GO:0016071 84 0.015
organelle localization GO:0051640 179 0.015
cellular protein catabolic process GO:0044257 155 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
microtubule based process GO:0007017 236 0.015
nuclear transport GO:0051169 139 0.015
protein ubiquitination GO:0016567 171 0.015
homeostasis of number of cells GO:0048872 210 0.015
axonogenesis GO:0007409 274 0.015
ribonucleotide catabolic process GO:0009261 208 0.014
transmembrane transport GO:0055085 412 0.014
cation transport GO:0006812 399 0.014
learning or memory GO:0007611 148 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
rna processing GO:0006396 105 0.014
digestive tract development GO:0048565 190 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
membrane organization GO:0061024 245 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
negative regulation of cell development GO:0010721 169 0.014
cognition GO:0050890 149 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
neuron death GO:0070997 154 0.014
regulation of histone modification GO:0031056 56 0.014
oocyte construction GO:0007308 2 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
stem cell development GO:0048864 219 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
response to growth factor GO:0070848 198 0.013
regulation of protein catabolic process GO:0042176 108 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
organelle fission GO:0048285 170 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
oxidation reduction process GO:0055114 342 0.013
endomembrane system organization GO:0010256 147 0.013
regulation of membrane potential GO:0042391 192 0.013
cytokinetic process GO:0032506 2 0.013
actin cytoskeleton organization GO:0030036 220 0.013
neuron apoptotic process GO:0051402 142 0.013
chemotaxis GO:0006935 247 0.013
response to peptide hormone GO:0043434 127 0.013
sensory perception GO:0007600 245 0.013
cellular homeostasis GO:0019725 240 0.013
regulation of intracellular transport GO:0032386 159 0.013
synaptic transmission GO:0007268 329 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
positive regulation of cell death GO:0010942 224 0.012
divalent inorganic cation transport GO:0072511 178 0.012
apoptotic signaling pathway GO:0097190 306 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
protein localization to nucleus GO:0034504 121 0.012
positive regulation of defense response GO:0031349 124 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
regulation of hormone levels GO:0010817 211 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
dephosphorylation GO:0016311 129 0.012
endodermal cell fate specification GO:0001714 4 0.012
muscle tissue development GO:0060537 308 0.012
activation of immune response GO:0002253 138 0.012
regulation of protein maturation GO:1903317 96 0.012
skin development GO:0043588 220 0.012
respiratory system development GO:0060541 190 0.012
peptide transport GO:0015833 133 0.012
striated muscle tissue development GO:0014706 293 0.012
heart morphogenesis GO:0003007 178 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
response to organic cyclic compound GO:0014070 198 0.012
developmental maturation GO:0021700 193 0.012
response to radiation GO:0009314 165 0.012
sensory organ morphogenesis GO:0090596 242 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
positive regulation of dna templated transcription elongation GO:0032786 2 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
regulation of protein transport GO:0051223 163 0.012
muscle cell differentiation GO:0042692 261 0.011
tissue homeostasis GO:0001894 115 0.011
epithelial cell development GO:0002064 159 0.011
response to acid chemical GO:0001101 111 0.011
cell division GO:0051301 120 0.011
blastocyst development GO:0001824 80 0.011
regulation of cell activation GO:0050865 289 0.011
defense response to other organism GO:0098542 197 0.011
digestive tract morphogenesis GO:0048546 147 0.011
inflammatory response GO:0006954 244 0.011
meiotic cell cycle GO:0051321 122 0.011
negative regulation of molecular function GO:0044092 258 0.011
amide transport GO:0042886 138 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
response to insulin GO:0032868 100 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
myosin filament assembly GO:0031034 2 0.011
glycerolipid metabolic process GO:0046486 122 0.011
cellular lipid metabolic process GO:0044255 323 0.011
b cell activation GO:0042113 161 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
protein import GO:0017038 101 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
mitochondrion distribution GO:0048311 4 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of cell motility GO:2000145 236 0.011
establishment of organelle localization GO:0051656 122 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
dendrite development GO:0016358 115 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
gene silencing GO:0016458 38 0.011
gonad development GO:0008406 141 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
regulation of chromatin organization GO:1902275 57 0.011
regulation of histone methylation GO:0031060 30 0.010
cilium assembly GO:0042384 81 0.010
gtp catabolic process GO:0006184 143 0.010
response to light stimulus GO:0009416 135 0.010
angiogenesis GO:0001525 201 0.010
skeletal system morphogenesis GO:0048705 203 0.010
rna interference GO:0016246 2 0.010
regulation of cell projection organization GO:0031344 206 0.010
divalent metal ion transport GO:0070838 172 0.010
double strand break repair GO:0006302 48 0.010
limb development GO:0060173 166 0.010
embryonic placenta development GO:0001892 98 0.010
regulation of cell migration GO:0030334 219 0.010
regulation of actin filament based process GO:0032970 99 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
asymmetric neuroblast division GO:0055059 1 0.010
cilium morphogenesis GO:0060271 102 0.010
gastrulation GO:0007369 116 0.010
stress activated mapk cascade GO:0051403 80 0.010
regulation of anatomical structure size GO:0090066 178 0.010
synapse organization GO:0050808 125 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
oocyte axis specification GO:0007309 2 0.010
blood vessel morphogenesis GO:0048514 285 0.010
regulation of neuron death GO:1901214 134 0.010
regulation of t cell activation GO:0050863 170 0.010
positive regulation of nervous system development GO:0051962 221 0.010

Heatr6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
immune system disease DOID:2914 0 0.017
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
hematopoietic system disease DOID:74 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011