Mus musculus

43 known processes

Cdkn2b

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

(Aliases: MTS2,AV083695,p15,p15(INK4b),p15INK4b,INK4b)

Cdkn2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of immune system process GO:0002683 209 0.308
Mouse
cell adhesion GO:0007155 329 0.188
regulation of leukocyte differentiation GO:1902105 159 0.173
Mouse
regulation of cell activation GO:0050865 289 0.165
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.158
cellular amino acid metabolic process GO:0006520 103 0.152
response to organic cyclic compound GO:0014070 198 0.150
Rat
negative regulation of phosphate metabolic process GO:0045936 184 0.143
Human Mouse
leukocyte differentiation GO:0002521 342 0.129
Mouse
male gamete generation GO:0048232 285 0.119
negative regulation of molecular function GO:0044092 258 0.114
Human Mouse
regulation of cell cycle GO:0051726 281 0.113
regulation of cellular amine metabolic process GO:0033238 20 0.112
leukocyte migration GO:0050900 124 0.110
negative regulation of lymphocyte activation GO:0051250 91 0.105
Mouse
regulation of lymphocyte activation GO:0051249 240 0.105
Mouse
cellular amine metabolic process GO:0044106 44 0.104
negative regulation of phosphorylation GO:0042326 166 0.103
Human Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.103
Human Mouse
t cell differentiation GO:0030217 174 0.100
Mouse
lymphocyte differentiation GO:0030098 242 0.100
Mouse
camera type eye development GO:0043010 266 0.099
positive regulation of programmed cell death GO:0043068 218 0.093
Mouse
germ cell development GO:0007281 185 0.092
cytokine production GO:0001816 319 0.091
negative regulation of t cell activation GO:0050868 65 0.085
Mouse
blood vessel morphogenesis GO:0048514 285 0.084
extracellular structure organization GO:0043062 148 0.082
regulation of cell motility GO:2000145 236 0.081
negative regulation of protein metabolic process GO:0051248 282 0.081
Human Mouse
negative regulation of protein maturation GO:1903318 79 0.079
Mouse
response to molecule of bacterial origin GO:0002237 143 0.078
regulation of cell adhesion GO:0030155 154 0.078
placenta development GO:0001890 140 0.076
negative regulation of cellular protein metabolic process GO:0032269 247 0.075
Human Mouse
response to acid chemical GO:0001101 111 0.075
negative regulation of cell activation GO:0050866 111 0.073
Mouse
positive regulation of cell death GO:0010942 224 0.073
Mouse
spermatogenesis GO:0007283 284 0.072
gland development GO:0048732 330 0.069
Mouse Rat
dna metabolic process GO:0006259 303 0.067
negative regulation of cell cycle GO:0045786 123 0.066
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.066
Mouse
extracellular matrix organization GO:0030198 147 0.065
t cell activation GO:0042110 289 0.063
Mouse
regulation of cellular catabolic process GO:0031329 242 0.063
Mouse
cell chemotaxis GO:0060326 81 0.063
nuclear division GO:0000280 158 0.063
stem cell development GO:0048864 219 0.063
Mouse
cell growth GO:0016049 130 0.062
Mouse
response to reactive oxygen species GO:0000302 56 0.062
Mouse
cellular ketone metabolic process GO:0042180 84 0.062
regulation of t cell activation GO:0050863 170 0.060
Mouse
striated muscle tissue development GO:0014706 293 0.057
developmental maturation GO:0021700 193 0.057
leukocyte chemotaxis GO:0030595 69 0.057
amine metabolic process GO:0009308 45 0.056
regulation of secretion GO:0051046 274 0.056
response to oxidative stress GO:0006979 123 0.056
Mouse
production of molecular mediator of immune response GO:0002440 103 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
positive regulation of protein modification process GO:0031401 299 0.054
organelle fission GO:0048285 170 0.053
negative regulation of protein modification process GO:0031400 163 0.053
Human Mouse
response to oxygen levels GO:0070482 62 0.052
alpha beta t cell differentiation GO:0046632 69 0.052
synaptic transmission GO:0007268 329 0.052
regulation of defense response GO:0031347 233 0.051
regulation of protein localization GO:0032880 231 0.050
apoptotic signaling pathway GO:0097190 306 0.050
protein maturation GO:0051604 176 0.050
Mouse
nephron development GO:0072006 109 0.049
protein modification by small protein conjugation or removal GO:0070647 207 0.048
Mouse
respiratory system development GO:0060541 190 0.047
regulation of organ morphogenesis GO:2000027 144 0.047
Mouse
regulation of t cell differentiation GO:0045580 83 0.047
Mouse
regulation of protein transport GO:0051223 163 0.047
regionalization GO:0003002 337 0.047
chemotaxis GO:0006935 247 0.047
dephosphorylation GO:0016311 129 0.046
ion transmembrane transport GO:0034220 361 0.046
single organism cell adhesion GO:0098602 156 0.046
muscle cell differentiation GO:0042692 261 0.046
myeloid leukocyte migration GO:0097529 57 0.045
organ growth GO:0035265 117 0.045
mitotic cell cycle process GO:1903047 159 0.045
intrinsic apoptotic signaling pathway GO:0097193 132 0.045
single organismal cell cell adhesion GO:0016337 131 0.044
regulation of intracellular transport GO:0032386 159 0.044
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.044
defense response to bacterium GO:0042742 119 0.044
regulation of proteolysis GO:0030162 164 0.044
Mouse
establishment of protein localization to organelle GO:0072594 118 0.043
transmembrane transport GO:0055085 412 0.043
cellular response to dna damage stimulus GO:0006974 207 0.043
mitotic cell cycle GO:0000278 195 0.043
lymphocyte proliferation GO:0046651 164 0.043
Mouse
homeostasis of number of cells GO:0048872 210 0.043
negative regulation of protein processing GO:0010955 79 0.042
Mouse
meiotic cell cycle GO:0051321 122 0.042
positive regulation of neuron differentiation GO:0045666 141 0.042
regulation of transferase activity GO:0051338 263 0.042
Human Mouse
regulation of hydrolase activity GO:0051336 246 0.041
modification dependent macromolecule catabolic process GO:0043632 133 0.041
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.041
Mouse
inflammatory response GO:0006954 244 0.041
fertilization GO:0009566 127 0.041
modification dependent protein catabolic process GO:0019941 133 0.041
Mouse
wound healing GO:0042060 157 0.041
cellular response to lipid GO:0071396 145 0.040
positive regulation of cell cycle GO:0045787 92 0.040
adaptive immune response GO:0002250 155 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
protein modification by small protein conjugation GO:0032446 187 0.040
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
response to inorganic substance GO:0010035 96 0.039
Mouse
adult behavior GO:0030534 135 0.039
response to drug GO:0042493 75 0.039
intracellular protein transport GO:0006886 204 0.039
morphogenesis of a branching epithelium GO:0061138 193 0.039
immune effector process GO:0002252 321 0.039
sensory organ morphogenesis GO:0090596 242 0.039
epithelial cell development GO:0002064 159 0.038
regulation of kinase activity GO:0043549 249 0.038
Human Mouse
response to nutrient levels GO:0031667 109 0.038
Human
regulation of protein serine threonine kinase activity GO:0071900 157 0.038
Human Mouse
regulation of mitotic cell cycle GO:0007346 126 0.038
response to lipopolysaccharide GO:0032496 128 0.038
regulation of hormone levels GO:0010817 211 0.038
positive regulation of apoptotic process GO:0043065 217 0.038
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.038
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.038
Human
response to growth factor GO:0070848 198 0.037
Human
regulation of neuron differentiation GO:0045664 281 0.037
macromolecule catabolic process GO:0009057 281 0.037
Mouse
epidermis development GO:0008544 187 0.037
Mouse
kidney epithelium development GO:0072073 121 0.037
cation transport GO:0006812 399 0.037
negative regulation of endopeptidase activity GO:0010951 44 0.036
steroid metabolic process GO:0008202 119 0.036
regulation of apoptotic signaling pathway GO:2001233 197 0.036
cellular response to acid chemical GO:0071229 68 0.035
regulation of cellular response to stress GO:0080135 159 0.035
regulation of establishment of protein localization GO:0070201 181 0.035
angiogenesis GO:0001525 201 0.034
cellular response to inorganic substance GO:0071241 37 0.034
regulation of protein processing GO:0070613 96 0.034
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.034
nitrogen compound transport GO:0071705 271 0.034
regulation of epithelial cell proliferation GO:0050678 141 0.034
Human Mouse
positive regulation of cell motility GO:2000147 116 0.034
epithelial cell proliferation GO:0050673 174 0.034
Human Mouse
amide transport GO:0042886 138 0.034
glomerular mesangial cell development GO:0072144 3 0.034
negative regulation of cell proliferation GO:0008285 296 0.033
Human Mouse Rat
negative regulation of t cell differentiation GO:0045581 23 0.033
Mouse
gastrulation GO:0007369 116 0.033
regulation of membrane potential GO:0042391 192 0.033
regulation of neuron projection development GO:0010975 169 0.033
cellular response to external stimulus GO:0071496 88 0.033
Human
positive regulation of cell activation GO:0050867 158 0.033
heterocycle catabolic process GO:0046700 280 0.032
segmentation GO:0035282 93 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
chromatin organization GO:0006325 206 0.032
protein targeting GO:0006605 143 0.032
protein ubiquitination GO:0016567 171 0.032
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.032
cellular response to oxidative stress GO:0034599 76 0.032
Mouse
positive regulation of cell migration GO:0030335 109 0.032
leukocyte activation involved in immune response GO:0002366 126 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
aromatic compound catabolic process GO:0019439 286 0.032
negative regulation of hydrolase activity GO:0051346 71 0.032
response to organonitrogen compound GO:0010243 246 0.031
hematopoietic progenitor cell differentiation GO:0002244 143 0.031
Human
heart morphogenesis GO:0003007 178 0.031
peptidyl amino acid modification GO:0018193 336 0.031
digestive tract development GO:0048565 190 0.031
positive regulation of defense response GO:0031349 124 0.031
response to decreased oxygen levels GO:0036293 59 0.031
cell type specific apoptotic process GO:0097285 268 0.030
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.030
ureteric bud development GO:0001657 94 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
fat cell differentiation GO:0045444 160 0.030
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.030
Mouse
regulation of cell cycle process GO:0010564 160 0.030
regulation of protein maturation GO:1903317 96 0.030
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.030
leukocyte mediated immunity GO:0002443 174 0.030
development of primary sexual characteristics GO:0045137 143 0.030
nephron epithelium development GO:0072009 92 0.029
regulation of protein catabolic process GO:0042176 108 0.029
Mouse
antimicrobial peptide biosynthetic process GO:0002777 2 0.029
response to amino acid GO:0043200 37 0.029
positive regulation of intracellular transport GO:0032388 70 0.029
regulation of secretion by cell GO:1903530 249 0.029
cytokine mediated signaling pathway GO:0019221 115 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
regulation of cell substrate adhesion GO:0010810 73 0.028
muscle tissue development GO:0060537 308 0.028
peptidyl tyrosine phosphorylation GO:0018108 143 0.028
antimicrobial peptide production GO:0002775 2 0.028
g1 s transition of mitotic cell cycle GO:0000082 57 0.028
central nervous system neuron differentiation GO:0021953 162 0.028
regulation of embryonic development GO:0045995 71 0.028
renal system development GO:0072001 225 0.027
chromatin modification GO:0016568 187 0.027
development of primary female sexual characteristics GO:0046545 73 0.027
negative regulation of transferase activity GO:0051348 85 0.027
Human Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.027
kidney morphogenesis GO:0060993 83 0.027
regulation of protein kinase activity GO:0045859 232 0.027
Human Mouse
carbohydrate metabolic process GO:0005975 230 0.027
intermediate filament cytoskeleton organization GO:0045104 26 0.027
oxidation reduction process GO:0055114 342 0.027
mitochondrion organization GO:0007005 134 0.027
regulation of monocyte chemotaxis GO:0090025 3 0.027
leukocyte degranulation GO:0043299 27 0.026
negative regulation of proteolysis GO:0045861 74 0.026
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.026
endomembrane system organization GO:0010256 147 0.026
carbohydrate homeostasis GO:0033500 128 0.026
Mouse
positive regulation of kinase activity GO:0033674 155 0.026
skeletal muscle organ development GO:0060538 163 0.026
cell activation involved in immune response GO:0002263 126 0.026
positive regulation of cell adhesion GO:0045785 80 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
positive regulation of nervous system development GO:0051962 221 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.025
regulation of mapk cascade GO:0043408 248 0.025
regulation of organelle organization GO:0033043 289 0.025
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
digestive system development GO:0055123 200 0.025
regulation of binding GO:0051098 111 0.025
Mouse
antibacterial peptide biosynthetic process GO:0002780 2 0.025
regulation of response to wounding GO:1903034 189 0.025
regulation of innate immune response GO:0045088 91 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.025
gonad development GO:0008406 141 0.025
leukocyte proliferation GO:0070661 172 0.024
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
protein catabolic process GO:0030163 221 0.024
Mouse
forebrain development GO:0030900 302 0.024
regulation of muscle tissue development GO:1901861 97 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
embryonic placenta development GO:0001892 98 0.024
positive regulation of secretion by cell GO:1903532 114 0.024
skeletal system morphogenesis GO:0048705 203 0.024
regulation of cytoplasmic transport GO:1903649 112 0.024
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
regulation of intracellular protein transport GO:0033157 82 0.023
intermediate filament based process GO:0045103 27 0.023
stem cell proliferation GO:0072089 117 0.023
response to metal ion GO:0010038 47 0.023
compound eye development GO:0048749 1 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
regulation of multi organism process GO:0043900 111 0.023
cellular response to amino acid stimulus GO:0071230 29 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
Human
peptidyl tyrosine modification GO:0018212 145 0.023
i kappab kinase nf kappab signaling GO:0007249 85 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
response to radiation GO:0009314 165 0.023
locomotory behavior GO:0007626 195 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
Human Mouse
neuronal action potential GO:0019228 54 0.023
regulation of peptidase activity GO:0052547 96 0.022
protein localization to organelle GO:0033365 185 0.022
peptide transport GO:0015833 133 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
regulation of interleukin 8 secretion GO:2000482 2 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
Mouse
positive regulation of secretion GO:0051047 130 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
stem cell differentiation GO:0048863 268 0.022
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
Mouse
protein import into nucleus GO:0006606 95 0.022
divalent metal ion transport GO:0070838 172 0.022
response to transforming growth factor beta GO:0071559 88 0.022
Human
negative regulation of cytokine production GO:0001818 84 0.021
alpha beta t cell activation GO:0046631 91 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
Human
reactive oxygen species metabolic process GO:0072593 84 0.021
skin development GO:0043588 220 0.021
Mouse
nephron tubule development GO:0072080 84 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
single fertilization GO:0007338 82 0.021
cellular response to starvation GO:0009267 57 0.021
regulation of cell projection organization GO:0031344 206 0.021
meiosis i GO:0007127 60 0.021
mapk cascade GO:0000165 281 0.020
t cell proliferation GO:0042098 120 0.020
Mouse
sensory perception GO:0007600 245 0.020
mesonephros development GO:0001823 97 0.020
endocytosis GO:0006897 168 0.020
activation of immune response GO:0002253 138 0.020
interleukin 8 secretion GO:0072606 3 0.020
neural tube development GO:0021915 160 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
positive regulation of leukocyte differentiation GO:1902107 86 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
negative regulation of leukocyte differentiation GO:1902106 51 0.020
Mouse
somitogenesis GO:0001756 69 0.020
spermatid differentiation GO:0048515 115 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
protein localization to nucleus GO:0034504 121 0.020
lung development GO:0030324 164 0.020
cardiac muscle tissue development GO:0048738 130 0.020
skeletal system development GO:0001501 356 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
b cell activation GO:0042113 161 0.020
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
regulation of organ growth GO:0046620 61 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
action potential GO:0001508 78 0.020
negative regulation of cell motility GO:2000146 61 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
divalent inorganic cation transport GO:0072511 178 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
interleukin 8 production GO:0032637 4 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
Mouse
regulation of chromosome organization GO:0033044 83 0.019
covalent chromatin modification GO:0016569 163 0.019
female gonad development GO:0008585 71 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
Mouse
negative regulation of peptidase activity GO:0010466 46 0.019
regulation of leukocyte proliferation GO:0070663 121 0.019
Mouse
organophosphate catabolic process GO:0046434 232 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
cellular response to organic cyclic compound GO:0071407 87 0.019
regulation of cytokine secretion GO:0050707 61 0.019
multicellular organism growth GO:0035264 161 0.019
positive regulation of immune effector process GO:0002699 107 0.019
regulation of cell growth GO:0001558 91 0.019
Mouse
regulation of eosinophil migration GO:2000416 2 0.019
protein processing GO:0016485 163 0.019
Mouse
regulation of t cell proliferation GO:0042129 92 0.019
Mouse
purine containing compound catabolic process GO:0072523 213 0.019
dna recombination GO:0006310 92 0.018
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.018
b cell mediated immunity GO:0019724 71 0.018
positive regulation of interleukin 6 secretion GO:2000778 1 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.018
polarity specification of proximal distal axis GO:0010085 2 0.018
female gamete generation GO:0007292 74 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.018
Human
epithelial tube formation GO:0072175 130 0.018
negative regulation of growth GO:0045926 99 0.018
Mouse
renal tubule development GO:0061326 87 0.018
sensory perception of mechanical stimulus GO:0050954 107 0.018
cell cycle g1 s phase transition GO:0044843 57 0.018
antibacterial peptide production GO:0002778 2 0.018
regulation of defense response to bacterium GO:1900424 3 0.018
positive regulation of epidermis development GO:0045684 13 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
cellular response to lipopolysaccharide GO:0071222 77 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
pole plasm assembly GO:0007315 2 0.018
defense response to other organism GO:0098542 197 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
response to calcium ion GO:0051592 20 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
cellular protein catabolic process GO:0044257 155 0.018
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.018
embryonic eye morphogenesis GO:0048048 29 0.018
tube formation GO:0035148 140 0.018
regulation of protein targeting GO:1903533 61 0.018
immunoglobulin production GO:0002377 73 0.017
organic hydroxy compound transport GO:0015850 93 0.017
rna processing GO:0006396 105 0.017
mesangial cell differentiation GO:0072007 4 0.017
response to tumor necrosis factor GO:0034612 26 0.017
regulation of b cell activation GO:0050864 81 0.017
Mouse
leukocyte apoptotic process GO:0071887 71 0.017
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.017
regulation of inflammatory response GO:0050727 147 0.017
spermatid development GO:0007286 108 0.017
regulation of kidney development GO:0090183 40 0.017
negative regulation of neuron differentiation GO:0045665 101 0.017
smooth muscle contraction GO:0006939 44 0.017
positive regulation of cell cycle process GO:0090068 61 0.017
immune response activating signal transduction GO:0002757 116 0.017
anion transport GO:0006820 177 0.017
peptide secretion GO:0002790 114 0.017
regulation of cellular response to growth factor stimulus GO:0090287 82 0.017
Human
connective tissue development GO:0061448 179 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
bmp signaling pathway GO:0030509 93 0.017
nephron morphogenesis GO:0072028 69 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
multi multicellular organism process GO:0044706 109 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
dna repair GO:0006281 107 0.017
cognition GO:0050890 149 0.017
response to hypoxia GO:0001666 58 0.017
hepaticobiliary system development GO:0061008 67 0.016
Rat
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.016
positive regulation of cytokine production GO:0001819 174 0.016
ossification GO:0001503 216 0.016
meiotic nuclear division GO:0007126 115 0.016
multicellular organismal signaling GO:0035637 91 0.016
gtp metabolic process GO:0046039 144 0.016
negative regulation of response to wounding GO:1903035 77 0.016
nucleotide catabolic process GO:0009166 217 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
microtubule based process GO:0007017 236 0.016
regulation of protein secretion GO:0050708 82 0.016
nephron epithelium morphogenesis GO:0072088 68 0.016
positive regulation of leukocyte mediated immunity GO:0002705 70 0.016
actin cytoskeleton organization GO:0030036 220 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
regulation of synaptic plasticity GO:0048167 87 0.016
signal transduction by p53 class mediator GO:0072331 51 0.016
positive regulation of protein transport GO:0051222 93 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
positive regulation of eosinophil migration GO:2000418 2 0.016
transcription from rna polymerase iii promoter GO:0006383 3 0.016
protein secretion GO:0009306 111 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
neural crest cell development GO:0014032 48 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
stem cell maintenance GO:0019827 130 0.016
Mouse
somatic sex determination GO:0018993 2 0.016
nephrogenic mesenchyme development GO:0072076 3 0.016
negative regulation of kinase activity GO:0033673 81 0.016
Human Mouse
cell substrate adhesion GO:0031589 130 0.016
gtp catabolic process GO:0006184 143 0.015
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.015
nucleoside metabolic process GO:0009116 246 0.015
response to extracellular stimulus GO:0009991 127 0.015
Human
somite development GO:0061053 81 0.015
endocrine system development GO:0035270 98 0.015
single organism nuclear import GO:1902593 95 0.015
leukocyte mediated cytotoxicity GO:0001909 62 0.015
limb development GO:0060173 166 0.015
regulation of ion transport GO:0043269 215 0.015
regulation of action potential GO:0098900 4 0.015
response to steroid hormone GO:0048545 56 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.015
ras protein signal transduction GO:0007265 77 0.015
neutrophil mediated immunity GO:0002446 19 0.015
mammary gland alveolus development GO:0060749 22 0.015
regulation of angiogenesis GO:0045765 81 0.015
exocytosis GO:0006887 121 0.015
response to retinoic acid GO:0032526 56 0.015
regulation of alpha beta t cell differentiation GO:0046637 35 0.015
mitotic nuclear division GO:0007067 48 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
regulation of stem cell proliferation GO:0072091 78 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
organelle localization GO:0051640 179 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
positive regulation of cytokine secretion GO:0050715 41 0.015
myotube differentiation GO:0014902 105 0.015
adult locomotory behavior GO:0008344 91 0.015
positive regulation of organelle organization GO:0010638 128 0.015
hindbrain development GO:0030902 128 0.015
glucose homeostasis GO:0042593 128 0.015
Mouse
glomerular mesangial cell differentiation GO:0072008 3 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
Human
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.015
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.015
mrna metabolic process GO:0016071 84 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
telencephalon development GO:0021537 186 0.015
sprouting angiogenesis GO:0002040 26 0.015
cellular response to extracellular stimulus GO:0031668 81 0.015
Human
midgut development GO:0007494 4 0.014
alcohol metabolic process GO:0006066 116 0.014
positive regulation of cell development GO:0010720 237 0.014
Mouse
cellular response to calcium ion GO:0071277 14 0.014
myeloid cell differentiation GO:0030099 233 0.014
Human
positive regulation of mitotic cell cycle GO:0045931 41 0.014
regulation of vasculature development GO:1901342 88 0.014
response to vitamin a GO:0033189 1 0.014

Cdkn2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.017