Mus musculus

0 known processes

Prps2

phosphoribosyl pyrophosphate synthetase 2

(Aliases: AI464149,AA589463,2610101M19Rik,Prps-2,MGC28388)

Prps2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.110
regulation of apoptotic signaling pathway GO:2001233 197 0.076
glial cell apoptotic process GO:0034349 3 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
cellular response to dna damage stimulus GO:0006974 207 0.065
purine ribonucleoside metabolic process GO:0046128 241 0.064
Rat
dna metabolic process GO:0006259 303 0.063
cellular amine metabolic process GO:0044106 44 0.062
cellular ketone metabolic process GO:0042180 84 0.062
purine nucleotide metabolic process GO:0006163 302 0.061
Rat
regulation of cell cycle process GO:0010564 160 0.060
cellular nitrogen compound catabolic process GO:0044270 280 0.058
regulation of organelle organization GO:0033043 289 0.058
glycosyl compound metabolic process GO:1901657 246 0.058
Rat
ribonucleoside metabolic process GO:0009119 245 0.058
Rat
purine nucleoside metabolic process GO:0042278 241 0.056
Rat
compound eye development GO:0048749 1 0.055
nucleoside triphosphate metabolic process GO:0009141 230 0.053
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
Rat
aromatic compound catabolic process GO:0019439 286 0.049
organophosphate catabolic process GO:0046434 232 0.049
regulation of cell activation GO:0050865 289 0.048
oxidation reduction process GO:0055114 342 0.048
amine metabolic process GO:0009308 45 0.044
heterocycle catabolic process GO:0046700 280 0.043
carbohydrate metabolic process GO:0005975 230 0.042
regulation of cell cycle GO:0051726 281 0.041
signal transduction involved in dna damage checkpoint GO:0072422 3 0.041
intrinsic apoptotic signaling pathway GO:0097193 132 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
Rat
ribose phosphate metabolic process GO:0019693 291 0.039
Yeast Rat
nucleoside phosphate catabolic process GO:1901292 222 0.039
nucleoside metabolic process GO:0009116 246 0.039
Rat
nucleoside monophosphate metabolic process GO:0009123 85 0.039
Rat
gonad development GO:0008406 141 0.038
cellular macromolecule catabolic process GO:0044265 206 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
synaptic transmission GO:0007268 329 0.038
purine nucleoside triphosphate metabolic process GO:0009144 226 0.038
apoptotic signaling pathway GO:0097190 306 0.037
protein catabolic process GO:0030163 221 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.036
macromolecule catabolic process GO:0009057 281 0.036
regulation of mitotic cell cycle GO:0007346 126 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
double strand break repair GO:0006302 48 0.035
spermatogenesis GO:0007283 284 0.035
negative regulation of protein phosphorylation GO:0001933 126 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
organic cyclic compound catabolic process GO:1901361 295 0.034
ribonucleoside monophosphate metabolic process GO:0009161 80 0.033
Rat
cellular lipid metabolic process GO:0044255 323 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
lipid biosynthetic process GO:0008610 179 0.032
ribonucleotide catabolic process GO:0009261 208 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
glycosyl compound catabolic process GO:1901658 206 0.030
purine containing compound catabolic process GO:0072523 213 0.030
epithelial tube morphogenesis GO:0060562 303 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.029
Rat
negative regulation of molecular function GO:0044092 258 0.029
membrane organization GO:0061024 245 0.028
axonogenesis GO:0007409 274 0.028
nucleotide catabolic process GO:0009166 217 0.028
organelle assembly GO:0070925 177 0.028
endocytosis GO:0006897 168 0.028
cytokine production GO:0001816 319 0.027
mrna metabolic process GO:0016071 84 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
negative regulation of phosphorylation GO:0042326 166 0.026
organelle fission GO:0048285 170 0.026
cellular homeostasis GO:0019725 240 0.026
purine nucleoside monophosphate metabolic process GO:0009126 81 0.026
Rat
purine nucleoside catabolic process GO:0006152 205 0.025
protein localization to organelle GO:0033365 185 0.025
transmembrane transport GO:0055085 412 0.025
development of primary sexual characteristics GO:0045137 143 0.025
negative regulation of cellular component organization GO:0051129 194 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
lipoprotein metabolic process GO:0042157 43 0.024
meiotic cell cycle GO:0051321 122 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
dna repair GO:0006281 107 0.024
cell division GO:0051301 120 0.023
protein localization to membrane GO:0072657 108 0.023
digestive tract development GO:0048565 190 0.023
urogenital system development GO:0001655 261 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
negative regulation of transferase activity GO:0051348 85 0.022
germ cell development GO:0007281 185 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
regulation of protein localization GO:0032880 231 0.022
receptor mediated endocytosis GO:0006898 51 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
peptidyl amino acid modification GO:0018193 336 0.022
negative regulation of protein modification process GO:0031400 163 0.022
nucleoside catabolic process GO:0009164 206 0.022
organic anion transport GO:0015711 137 0.022
atp metabolic process GO:0046034 75 0.022
myeloid cell differentiation GO:0030099 233 0.021
muscle cell differentiation GO:0042692 261 0.021
leukocyte differentiation GO:0002521 342 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
meiotic nuclear division GO:0007126 115 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
Rat
nucleoside phosphate metabolic process GO:0006753 338 0.021
Rat
negative regulation of cell cycle GO:0045786 123 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
Yeast Rat
cellular response to gamma radiation GO:0071480 4 0.021
leukocyte proliferation GO:0070661 172 0.020
ion transmembrane transport GO:0034220 361 0.020
purine containing compound metabolic process GO:0072521 311 0.020
Rat
regulation of lymphocyte activation GO:0051249 240 0.020
digestive system development GO:0055123 200 0.020
positive regulation of cell development GO:0010720 237 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
cellular protein complex assembly GO:0043623 116 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
anion transport GO:0006820 177 0.019
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.019
negative regulation of kinase activity GO:0033673 81 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
intracellular protein transport GO:0006886 204 0.019
cellular amino acid metabolic process GO:0006520 103 0.019
negative regulation of immune system process GO:0002683 209 0.019
nuclear division GO:0000280 158 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
regulation of membrane potential GO:0042391 192 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
anatomical structure homeostasis GO:0060249 145 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
cellular protein catabolic process GO:0044257 155 0.018
cytoplasmic transport GO:0016482 234 0.018
cell fate commitment GO:0045165 210 0.018
innate immune response GO:0045087 157 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
cation transport GO:0006812 399 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 3 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
defecation GO:0030421 1 0.017
multi multicellular organism process GO:0044706 109 0.017
inflammatory response GO:0006954 244 0.017
glycerolipid metabolic process GO:0046486 122 0.017
inositol phosphate catabolic process GO:0071545 4 0.017
fat cell differentiation GO:0045444 160 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
developmental cell growth GO:0048588 84 0.016
negative regulation of organelle organization GO:0010639 90 0.016
sensory perception GO:0007600 245 0.016
rna interference GO:0016246 2 0.016
positive regulation of cell death GO:0010942 224 0.016
lateral inhibition GO:0046331 1 0.016
developmental maturation GO:0021700 193 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
regulation of protein kinase activity GO:0045859 232 0.016
protein secretion GO:0009306 111 0.016
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.016
organic acid transport GO:0015849 101 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
chromatin modification GO:0016568 187 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
stem cell differentiation GO:0048863 268 0.015
multicellular organism growth GO:0035264 161 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of interleukin 1 alpha production GO:0032650 4 0.015
regulation of hormone levels GO:0010817 211 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
skeletal muscle organ development GO:0060538 163 0.015
respiratory system development GO:0060541 190 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
somatic cell dna recombination GO:0016444 51 0.015
microtubule based process GO:0007017 236 0.015
regulation of secretion GO:0051046 274 0.015
nucleotide metabolic process GO:0009117 332 0.015
Rat
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.015
rna processing GO:0006396 105 0.015
response to organonitrogen compound GO:0010243 246 0.015
establishment of organelle localization GO:0051656 122 0.014
regulation of defense response GO:0031347 233 0.014
nitrogen compound transport GO:0071705 271 0.014
carboxylic acid transport GO:0046942 100 0.014
male gamete generation GO:0048232 285 0.014
regulation of neuron death GO:1901214 134 0.014
regulation of cytokine production GO:0001817 266 0.014
positive regulation of protein modification process GO:0031401 299 0.014
transition metal ion transport GO:0000041 38 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
epithelial cell proliferation GO:0050673 174 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
gland development GO:0048732 330 0.014
response to radiation GO:0009314 165 0.014
cellular chemical homeostasis GO:0055082 215 0.014
lymphocyte differentiation GO:0030098 242 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
regulation of transferase activity GO:0051338 263 0.014
defense response to other organism GO:0098542 197 0.014
blood circulation GO:0008015 195 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
cell junction organization GO:0034330 77 0.013
neural tube development GO:0021915 160 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
Rat
lung development GO:0030324 164 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
maintenance of location GO:0051235 89 0.013
cation transmembrane transport GO:0098655 266 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
alcohol metabolic process GO:0006066 116 0.013
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.013
cell adhesion GO:0007155 329 0.013
male anatomical structure morphogenesis GO:0090598 4 0.013
cellular response to radiation GO:0071478 28 0.013
renal system development GO:0072001 225 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
regionalization GO:0003002 337 0.012
striated muscle cell development GO:0055002 125 0.012
rhythmic process GO:0048511 174 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
plasma membrane organization GO:0007009 90 0.012
negative regulation of cell activation GO:0050866 111 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
positive regulation of nervous system development GO:0051962 221 0.012
response to organic cyclic compound GO:0014070 198 0.012
regulation of system process GO:0044057 200 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
response to light stimulus GO:0009416 135 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
digestive tract morphogenesis GO:0048546 147 0.012
regulation of actin filament based process GO:0032970 99 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
response to lipopolysaccharide GO:0032496 128 0.012
substantia nigra development GO:0021762 2 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
Rat
neural tube formation GO:0001841 108 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
Yeast Rat
amp metabolic process GO:0046033 4 0.012
Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
nucleoside biosynthetic process GO:0009163 21 0.012
Rat
muscle cell development GO:0055001 133 0.012
cell growth GO:0016049 130 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
learning or memory GO:0007611 148 0.012
antimicrobial peptide biosynthetic process GO:0002777 2 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
fatty acid metabolic process GO:0006631 121 0.011
cell maturation GO:0048469 127 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
cellularization GO:0007349 1 0.011
mitotic cell cycle GO:0000278 195 0.011
b cell proliferation GO:0042100 53 0.011
wnt signaling pathway GO:0016055 188 0.011
ovulation cycle GO:0042698 59 0.011
regulation of cell division GO:0051302 76 0.011
regulation of mapk cascade GO:0043408 248 0.011
posttranscriptional gene silencing GO:0016441 10 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
tube formation GO:0035148 140 0.011
t cell activation GO:0042110 289 0.011
response to ionizing radiation GO:0010212 42 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
Rat
circulatory system process GO:0003013 197 0.011
blood vessel morphogenesis GO:0048514 285 0.011
protein maturation GO:0051604 176 0.011
chromatin organization GO:0006325 206 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
sequestering of metal ion GO:0051238 19 0.011
response to oxidative stress GO:0006979 123 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
protein polymerization GO:0051258 57 0.011
kidney development GO:0001822 213 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
striated muscle tissue development GO:0014706 293 0.011
regulation of endocytosis GO:0030100 69 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
amp biosynthetic process GO:0006167 2 0.011
Rat
rna catabolic process GO:0006401 29 0.011
heterochromatin organization GO:0070828 4 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
muscle tissue development GO:0060537 308 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of protein catabolic process GO:0042176 108 0.011
chemotaxis GO:0006935 247 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.010
organic acid biosynthetic process GO:0016053 86 0.010
mitotic g1 dna damage checkpoint GO:0031571 4 0.010
amino acid transport GO:0006865 61 0.010
positive regulation of growth GO:0045927 104 0.010
mitotic nuclear division GO:0007067 48 0.010
female sex differentiation GO:0046660 84 0.010
histone modification GO:0016570 159 0.010
regulation of kinase activity GO:0043549 249 0.010
methylation GO:0032259 134 0.010
cellular response to oxidative stress GO:0034599 76 0.010
negative regulation of cell cycle process GO:0010948 69 0.010
response to extracellular stimulus GO:0009991 127 0.010
respiratory tube development GO:0030323 167 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
regulation of nuclear division GO:0051783 56 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
fertilization GO:0009566 127 0.010

Prps2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.037
nervous system disease DOID:863 0 0.037
disease of anatomical entity DOID:7 0 0.037
neurodegenerative disease DOID:1289 0 0.022
disease of metabolism DOID:0014667 0 0.019
disease of cellular proliferation DOID:14566 0 0.014
inherited metabolic disorder DOID:655 0 0.012
focal segmental glomerulosclerosis DOID:1312 0 0.012
kidney disease DOID:557 0 0.012
glomerulonephritis DOID:2921 0 0.012
nephritis DOID:10952 0 0.012
glomerulosclerosis DOID:0050851 0 0.012
urinary system disease DOID:18 0 0.012
disease of mental health DOID:150 0 0.011