Mus musculus

0 known processes

Klf3

Kruppel-like factor 3 (basic)

(Aliases: Tef-2,9930027G08Rik,Bklf,MGC151315,AL024007)

Klf3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
activation of mapk activity involved in innate immune response GO:0035419 2 0.998
clara cell differentiation GO:0060486 4 0.975
extracellular matrix dependent thymocyte migration GO:0072680 1 0.957
regulation of map kinase activity GO:0043405 120 0.956
lens morphogenesis in camera type eye GO:0002089 24 0.926
negative regulation of cell proliferation GO:0008285 296 0.897
Mouse
fibronectin dependent thymocyte migration GO:0072681 1 0.833
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.810
aortic valve morphogenesis GO:0003180 4 0.790
regulation of kinase activity GO:0043549 249 0.778
myelination in peripheral nervous system GO:0022011 19 0.774
single organismal cell cell adhesion GO:0016337 131 0.761
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.760
prevention of polyspermy GO:0060468 4 0.751
positive regulation of epidermal growth factor activated receptor activity GO:0045741 2 0.713
positive regulation of thymocyte migration GO:2000412 2 0.697
stem cell development GO:0048864 219 0.688
Mouse
rac protein signal transduction GO:0016601 13 0.680
regulation of transferase activity GO:0051338 263 0.673
regulation of mapk cascade GO:0043408 248 0.659
megakaryocyte differentiation GO:0030219 26 0.648
cell adhesion GO:0007155 329 0.642
septum primum development GO:0003284 4 0.626
ras protein signal transduction GO:0007265 77 0.614
regionalization GO:0003002 337 0.607
t cell activation GO:0042110 289 0.606
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.602
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.595
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.592
regulation of cellular ketone metabolic process GO:0010565 66 0.580
schwann cell differentiation GO:0014037 26 0.568
cellular ketone metabolic process GO:0042180 84 0.562
positive regulation of protein phosphorylation GO:0001934 242 0.533
regulation of protein serine threonine kinase activity GO:0071900 157 0.530
positive regulation of transferase activity GO:0051347 167 0.527
heart trabecula morphogenesis GO:0061384 26 0.511
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.508
positive regulation of protein modification process GO:0031401 299 0.496
positive regulation of eosinophil migration GO:2000418 2 0.496
regulation of cellular catabolic process GO:0031329 242 0.494
mitral valve morphogenesis GO:0003183 4 0.477
single organism cell adhesion GO:0098602 156 0.471
cardiac septum morphogenesis GO:0060411 46 0.457
ventricular septum morphogenesis GO:0060412 27 0.453
positive regulation of map kinase activity GO:0043406 84 0.452
negative regulation of myeloid cell differentiation GO:0045638 38 0.451
gene looping GO:0090202 2 0.442
striated muscle tissue development GO:0014706 293 0.438
Mouse
myeloid cell homeostasis GO:0002262 114 0.429
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.427
cellular amino acid metabolic process GO:0006520 103 0.426
regulation of lymphocyte activation GO:0051249 240 0.422
regulation of rho gtpase activity GO:0032319 58 0.416
membrane protein proteolysis GO:0033619 10 0.401
regulation of neural precursor cell proliferation GO:2000177 70 0.401
cardiac muscle tissue development GO:0048738 130 0.397
histone modification GO:0016570 159 0.397
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.396
small gtpase mediated signal transduction GO:0007264 97 0.396
positive regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000309 1 0.388
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.384
positive regulation of mapk cascade GO:0043410 170 0.383
lung development GO:0030324 164 0.368
Mouse
heart morphogenesis GO:0003007 178 0.368
t cell differentiation GO:0030217 174 0.367
homeostasis of number of cells GO:0048872 210 0.366
Mouse
aromatic compound catabolic process GO:0019439 286 0.365
synaptic transmission GO:0007268 329 0.362
rho protein signal transduction GO:0007266 32 0.359
pulmonary valve morphogenesis GO:0003184 5 0.359
t cell differentiation in thymus GO:0033077 77 0.356
heart valve development GO:0003170 23 0.354
regulation of eosinophil migration GO:2000416 2 0.354
developmental maturation GO:0021700 193 0.352
Mouse
cardioblast migration GO:0003260 1 0.351
eosinophil migration GO:0072677 3 0.342
regulation of purine nucleotide metabolic process GO:1900542 169 0.334
positive regulation of lymphocyte activation GO:0051251 140 0.331
regulation of gtp catabolic process GO:0033124 113 0.328
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.327
blood vessel morphogenesis GO:0048514 285 0.326
Mouse
cardiac chamber development GO:0003205 108 0.323
intestinal epithelial cell differentiation GO:0060575 14 0.323
Mouse
kidney development GO:0001822 213 0.322
Mouse
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.319
embryonic organ morphogenesis GO:0048562 276 0.319
regulation of cellular amino acid metabolic process GO:0006521 5 0.317
heart process GO:0003015 94 0.316
embryonic placenta development GO:0001892 98 0.313
regulation of rho protein signal transduction GO:0035023 71 0.312
regulation of leukocyte differentiation GO:1902105 159 0.311
striated muscle hypertrophy GO:0014897 24 0.310
Mouse
ventricular septum development GO:0003281 42 0.308
cardiac septum development GO:0003279 59 0.308
negative regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000734 1 0.299
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.299
regulation of thymocyte migration GO:2000410 2 0.298
lens development in camera type eye GO:0002088 62 0.296
regulation of histone h3 k4 methylation GO:0051569 12 0.290
regulation of multi organism process GO:0043900 111 0.287
positive regulation of cardioblast differentiation GO:0051891 3 0.284
stem cell differentiation GO:0048863 268 0.283
Mouse
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.282
regulation of cell adhesion GO:0030155 154 0.281
regulation of myeloid cell differentiation GO:0045637 96 0.279
parathyroid hormone secretion GO:0035898 2 0.278
positive regulation of cellular amine metabolic process GO:0033240 5 0.277
transcriptional activation by promoter enhancer looping GO:0071733 2 0.274
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.269
purine containing compound metabolic process GO:0072521 311 0.262
regulation of response to wounding GO:1903034 189 0.259
regulation of nucleotide metabolic process GO:0006140 169 0.255
positive regulation of kinase activity GO:0033674 155 0.252
regulation of protein kinase activity GO:0045859 232 0.247
regulation of peptide hormone secretion GO:0090276 75 0.246
epithelial tube formation GO:0072175 130 0.246
regulation of neuron apoptotic process GO:0043523 122 0.242
peptide hormone secretion GO:0030072 109 0.241
atrial septum primum morphogenesis GO:0003289 3 0.240
cardiac muscle tissue morphogenesis GO:0055008 44 0.239
mapk cascade GO:0000165 281 0.238
negative regulation of phosphorus metabolic process GO:0010563 184 0.237
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 0.234
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.233
cell migration to the midline involved in heart development GO:0003318 1 0.232
sensory organ morphogenesis GO:0090596 242 0.226
cell type specific apoptotic process GO:0097285 268 0.226
muscle adaptation GO:0043500 39 0.225
Mouse
peptidyl amino acid modification GO:0018193 336 0.225
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.223
hematopoietic progenitor cell differentiation GO:0002244 143 0.222
primary neural tube formation GO:0014020 95 0.221
regulation of proteolysis GO:0030162 164 0.216
chromatin organization GO:0006325 206 0.215
Mouse
cell cell signaling involved in metanephros development GO:0072204 2 0.214
angiogenesis GO:0001525 201 0.213
Mouse
atrioventricular valve formation GO:0003190 5 0.213
regulation of t cell differentiation GO:0045580 83 0.212
regulation of cytokine production GO:0001817 266 0.212
gland development GO:0048732 330 0.211
Mouse
lymphocyte differentiation GO:0030098 242 0.209
wnt signaling pathway GO:0016055 188 0.208
thymocyte migration GO:0072679 2 0.208
kidney epithelium development GO:0072073 121 0.204
Mouse
erythrocyte differentiation GO:0030218 88 0.204
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.204
regulation of reproductive process GO:2000241 66 0.203
neural precursor cell proliferation GO:0061351 121 0.201
epithelial tube morphogenesis GO:0060562 303 0.199
regulation of cell migration GO:0030334 219 0.198
endocardial cushion development GO:0003197 26 0.198
lymphocyte proliferation GO:0046651 164 0.197
positive regulation of programmed cell death GO:0043068 218 0.196
regulation of t cell activation GO:0050863 170 0.195
pulmonary valve development GO:0003177 5 0.195
insulin secretion GO:0030073 89 0.194
leukocyte differentiation GO:0002521 342 0.193
activation of mapk activity GO:0000187 59 0.192
neuron apoptotic process GO:0051402 142 0.190
g1 s transition of mitotic cell cycle GO:0000082 57 0.190
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.190
regulation of cardioblast differentiation GO:0051890 3 0.188
heart trabecula formation GO:0060347 14 0.186
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.183
amine metabolic process GO:0009308 45 0.180
epidermis development GO:0008544 187 0.178
Mouse
negative regulation of macrophage differentiation GO:0045650 4 0.178
covalent chromatin modification GO:0016569 163 0.177
regulation of ureteric bud formation GO:0072106 3 0.176
regulation of cell cycle GO:0051726 281 0.173
axonogenesis GO:0007409 274 0.173
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.171
cellular nitrogen compound catabolic process GO:0044270 280 0.170
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.169
response to organic cyclic compound GO:0014070 198 0.165
cardiac ventricle development GO:0003231 83 0.164
regulation of protein kinase b signaling GO:0051896 56 0.162
b cell activation GO:0042113 161 0.162
chromatin modification GO:0016568 187 0.162
Mouse
liver development GO:0001889 66 0.159
Mouse
segmentation GO:0035282 93 0.158
telencephalon development GO:0021537 186 0.156
urogenital system development GO:0001655 261 0.155
Mouse
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.155
response to fibroblast growth factor GO:0071774 47 0.154
muscle tissue development GO:0060537 308 0.153
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.153
cellular amine metabolic process GO:0044106 44 0.153
cardiac muscle adaptation GO:0014887 10 0.150
Mouse
striated muscle cell proliferation GO:0014855 39 0.150
adaptive immune response GO:0002250 155 0.150
outflow tract morphogenesis GO:0003151 53 0.150
leukocyte proliferation GO:0070661 172 0.149
negative regulation of neural precursor cell proliferation GO:2000178 18 0.147
peptide transport GO:0015833 133 0.146
cardiac epithelial to mesenchymal transition GO:0060317 18 0.146
germ cell development GO:0007281 185 0.145
cytokine production GO:0001816 319 0.144
organophosphate catabolic process GO:0046434 232 0.143
regulation of interleukin 8 production GO:0032677 3 0.141
regulation of lymphocyte differentiation GO:0045619 107 0.141
hormone secretion GO:0046879 128 0.140
glycosyl compound catabolic process GO:1901658 206 0.139
lateral inhibition GO:0046331 1 0.138
lung lobe formation GO:0060464 1 0.138
adult behavior GO:0030534 135 0.136
regulation of cell activation GO:0050865 289 0.136
embryonic heart tube development GO:0035050 65 0.136
regulation of t cell proliferation GO:0042129 92 0.135
response to corticosteroid GO:0031960 20 0.135
cellular lipid metabolic process GO:0044255 323 0.135
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.133
regulation of ras gtpase activity GO:0032318 88 0.133
regulation of neuron differentiation GO:0045664 281 0.133
skin development GO:0043588 220 0.132
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.131
neuron projection guidance GO:0097485 141 0.130
Mouse
camera type eye development GO:0043010 266 0.129
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.128
nitrogen compound transport GO:0071705 271 0.125
actin filament organization GO:0007015 113 0.123
negative regulation of fertilization GO:0060467 5 0.123
dsdna loop formation GO:0090579 2 0.123
positive regulation of growth GO:0045927 104 0.122
regulation of purine nucleotide catabolic process GO:0033121 122 0.121
neuron death GO:0070997 154 0.121
gtp catabolic process GO:0006184 143 0.120
negative regulation of interleukin 8 production GO:0032717 1 0.120
ossification GO:0001503 216 0.120
histone h3 k4 methylation GO:0051568 23 0.119
striated muscle adaptation GO:0014888 26 0.119
Mouse
positive regulation of cell death GO:0010942 224 0.119
pro t cell differentiation GO:0002572 3 0.118
positive regulation of gtpase activity GO:0043547 85 0.118
ribose phosphate metabolic process GO:0019693 291 0.118
macromolecule catabolic process GO:0009057 281 0.117
regulation of neuron death GO:1901214 134 0.117
positive regulation of apoptotic process GO:0043065 217 0.116
cellular response to hormone stimulus GO:0032870 150 0.116
positive regulation of interleukin 13 production GO:0032736 4 0.116
epithelial to mesenchymal transition GO:0001837 47 0.116
embryonic epithelial tube formation GO:0001838 130 0.115
digestive tract morphogenesis GO:0048546 147 0.115
protein kinase b signaling GO:0043491 74 0.114
phospholipid metabolic process GO:0006644 87 0.113
glomerulus development GO:0032835 40 0.112
Mouse
regulation of organelle organization GO:0033043 289 0.112
lung cell differentiation GO:0060479 30 0.111
Mouse
methylation GO:0032259 134 0.111
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.110
regulation of muscle tissue development GO:1901861 97 0.110
negative regulation of fat cell differentiation GO:0045599 36 0.110
axon guidance GO:0007411 141 0.109
Mouse
ribonucleoside catabolic process GO:0042454 206 0.109
notochord formation GO:0014028 5 0.109
leukocyte migration involved in inflammatory response GO:0002523 7 0.108
organonitrogen compound catabolic process GO:1901565 264 0.107
mesenchyme development GO:0060485 152 0.107
guanosine containing compound metabolic process GO:1901068 144 0.107
lymphocyte apoptotic process GO:0070227 54 0.107
spermatogenesis GO:0007283 284 0.106
mitral valve development GO:0003174 4 0.105
tube formation GO:0035148 140 0.105
epithelial cell proliferation GO:0050673 174 0.104
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.104
neural tube development GO:0021915 160 0.104
lymphocyte homeostasis GO:0002260 64 0.103
b cell homeostasis GO:0001782 34 0.103
regulation of cell proliferation involved in mesonephros development GO:2000606 1 0.102
blood circulation GO:0008015 195 0.102
antigen receptor mediated signaling pathway GO:0050851 64 0.102
ribonucleotide catabolic process GO:0009261 208 0.102
ectoderm formation GO:0001705 3 0.102
cell migration involved in heart formation GO:0060974 1 0.101
multicellular organism growth GO:0035264 161 0.101
Mouse
epithelial cell differentiation involved in kidney development GO:0035850 23 0.101
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.100
positive regulation of ureteric bud formation GO:0072107 3 0.098
activation of immune response GO:0002253 138 0.097
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.097
schwann cell development GO:0014044 22 0.097
digestive system development GO:0055123 200 0.097
Mouse
regulation of receptor activity GO:0010469 41 0.095
ovulation GO:0030728 15 0.095
negative regulation of nervous system development GO:0051961 156 0.095
immune response regulating signaling pathway GO:0002764 125 0.095
regulation of nucleotide catabolic process GO:0030811 122 0.094
cardiac muscle hypertrophy GO:0003300 23 0.094
Mouse
response to steroid hormone GO:0048545 56 0.094
peptide secretion GO:0002790 114 0.094
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.094
ensheathment of neurons GO:0007272 76 0.093
t cell proliferation GO:0042098 120 0.093
cellular response to growth factor stimulus GO:0071363 197 0.093
regulation of cellular component biogenesis GO:0044087 181 0.092
Mouse
determination of left right symmetry GO:0007368 80 0.092
wnt signaling pathway involved in kidney development GO:0061289 2 0.091
nucleoside phosphate metabolic process GO:0006753 338 0.090
muscle tissue morphogenesis GO:0060415 53 0.090
positive regulation of leukocyte differentiation GO:1902107 86 0.090
regulation of rac protein signal transduction GO:0035020 19 0.090
regulation of cardiac muscle tissue development GO:0055024 31 0.089
regulation of hormone levels GO:0010817 211 0.089
response to monosaccharide GO:0034284 67 0.088
regulation of definitive erythrocyte differentiation GO:0010724 3 0.087
spleen development GO:0048536 39 0.087
leukocyte homeostasis GO:0001776 79 0.087
central nervous system projection neuron axonogenesis GO:0021952 21 0.086
regulation of leukocyte proliferation GO:0070663 121 0.086
interleukin 8 production GO:0032637 4 0.086
male gamete generation GO:0048232 285 0.085
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.085
multicellular organismal homeostasis GO:0048871 164 0.085
purine nucleoside triphosphate catabolic process GO:0009146 203 0.085
positive regulation of response to wounding GO:1903036 66 0.085
negative regulation of cell cycle GO:0045786 123 0.085
neural tube formation GO:0001841 108 0.084
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.084
apoptotic signaling pathway GO:0097190 306 0.084
myelination GO:0042552 74 0.084
nucleotide catabolic process GO:0009166 217 0.084
heart growth GO:0060419 45 0.083
cellular response to glucocorticoid stimulus GO:0071385 13 0.083
heterocycle catabolic process GO:0046700 280 0.083
definitive hemopoiesis GO:0060216 20 0.083
skeletal muscle organ development GO:0060538 163 0.082
Mouse
mesodermal cell migration GO:0008078 4 0.082
g protein coupled receptor signaling pathway GO:0007186 243 0.080
regulation of protein binding GO:0043393 60 0.080
cell cycle g1 s phase transition GO:0044843 57 0.080
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.080
regulation of forebrain neuron differentiation GO:2000977 2 0.079
positive regulation of proteolysis GO:0045862 85 0.079
protein methylation GO:0006479 81 0.079
digestive tract development GO:0048565 190 0.079
Mouse
macromolecule methylation GO:0043414 120 0.078
oocyte construction GO:0007308 2 0.078
nucleoside phosphate catabolic process GO:1901292 222 0.077
regulation of system process GO:0044057 200 0.077
purine ribonucleotide catabolic process GO:0009154 208 0.077
myeloid cell differentiation GO:0030099 233 0.076
Mouse
purine nucleotide metabolic process GO:0006163 302 0.073
purine ribonucleotide metabolic process GO:0009150 290 0.073
mesenchymal cell development GO:0014031 93 0.073
positive regulation of protein kinase b signaling GO:0051897 32 0.072
muscle cell proliferation GO:0033002 52 0.072
cell differentiation involved in kidney development GO:0061005 33 0.072
Mouse
regulation of body fluid levels GO:0050878 162 0.072
membrane protein ectodomain proteolysis GO:0006509 7 0.072
positive regulation of megakaryocyte differentiation GO:0045654 4 0.071
tricuspid valve development GO:0003175 3 0.071
heart contraction GO:0060047 93 0.070
regulation of inflammatory response GO:0050727 147 0.070
heart valve morphogenesis GO:0003179 21 0.069
female gamete generation GO:0007292 74 0.069
mesoderm morphogenesis GO:0048332 64 0.069
positive regulation of cell activation GO:0050867 158 0.068
response to follicle stimulating hormone GO:0032354 1 0.068
negative regulation of cell proliferation involved in mesonephros development GO:2000607 1 0.068
cellular homeostasis GO:0019725 240 0.068
muscle hypertrophy GO:0014896 24 0.067
Mouse
muscle system process GO:0003012 141 0.067
Mouse
purine nucleotide catabolic process GO:0006195 211 0.067
hindbrain development GO:0030902 128 0.067
regulation of homeostatic process GO:0032844 182 0.066
nephron development GO:0072006 109 0.066
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.066
learning or memory GO:0007611 148 0.066
organic cyclic compound catabolic process GO:1901361 295 0.066
negative regulation of synapse assembly GO:0051964 3 0.066
blood vessel lumenization GO:0072554 2 0.066
regulation of peptide transport GO:0090087 91 0.065
positive regulation of t cell differentiation GO:0045582 52 0.065
amide transport GO:0042886 138 0.064
mitotic cell cycle process GO:1903047 159 0.064
compartment pattern specification GO:0007386 4 0.063
positive regulation of homeostatic process GO:0032846 64 0.063
t cell apoptotic process GO:0070231 39 0.063
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.063
mitotic cell cycle GO:0000278 195 0.062
muscle hypertrophy in response to stress GO:0003299 10 0.062
Mouse
smad protein signal transduction GO:0060395 21 0.062
cerebellar granule cell precursor tangential migration GO:0021935 1 0.062
regulation of feeding behavior GO:0060259 3 0.062
actin cytoskeleton organization GO:0030036 220 0.062
gtp metabolic process GO:0046039 144 0.062
protein alkylation GO:0008213 81 0.062
protein autophosphorylation GO:0046777 61 0.062
glial cell development GO:0021782 54 0.061
carbon catabolite activation of transcription GO:0045991 4 0.061
nephron epithelium development GO:0072009 92 0.061
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
embryonic heart tube morphogenesis GO:0003143 51 0.061
lung epithelial cell differentiation GO:0060487 29 0.060
Mouse
cardiac cell fate determination GO:0060913 2 0.060
regulation of heart contraction GO:0008016 77 0.060
intestinal epithelial cell development GO:0060576 12 0.060
Mouse
regulation of cardiac muscle tissue growth GO:0055021 26 0.059
b cell differentiation GO:0030183 78 0.059
fertilization GO:0009566 127 0.059
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.059
positive regulation of ras gtpase activity GO:0032320 65 0.059
lung secretory cell differentiation GO:0061140 13 0.058
regulation of erk1 and erk2 cascade GO:0070372 71 0.058
respiratory system development GO:0060541 190 0.058
Mouse
endodermal cell fate commitment GO:0001711 12 0.058
cellular response to dna damage stimulus GO:0006974 207 0.058
negative regulation of multi organism process GO:0043901 68 0.058
regulation of hydrolase activity GO:0051336 246 0.057
ventricular cardiac muscle tissue development GO:0003229 38 0.057
negative regulation of immune system process GO:0002683 209 0.057
purine ribonucleoside metabolic process GO:0046128 241 0.057
nucleoside catabolic process GO:0009164 206 0.057
regulation of epidermal cell differentiation GO:0045604 21 0.057
oocyte axis specification GO:0007309 2 0.057
apical constriction GO:0003383 4 0.057
response to glucocorticoid GO:0051384 20 0.057
left right pattern formation GO:0060972 23 0.057
aortic valve development GO:0003176 5 0.057
cardiocyte differentiation GO:0035051 87 0.056
stem cell maintenance GO:0019827 130 0.056
Mouse
negative regulation of cell development GO:0010721 169 0.056
action potential GO:0001508 78 0.056
atrioventricular valve morphogenesis GO:0003181 13 0.056
positive regulation of transcription regulatory region dna binding GO:2000679 1 0.056
stat protein import into nucleus GO:0007262 6 0.056
fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000699 1 0.056
regulation of hormone secretion GO:0046883 88 0.056
regulation of neuronal synaptic plasticity GO:0048168 30 0.055
positive regulation of cell adhesion GO:0045785 80 0.055
lung epithelium development GO:0060428 37 0.055
Mouse
regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000733 1 0.055
negative regulation of neuron death GO:1901215 98 0.055
regulation of lymphocyte apoptotic process GO:0070228 41 0.054
atrioventricular canal development GO:0036302 5 0.054
regulation of ras protein signal transduction GO:0046578 114 0.054
lymphocyte migration GO:0072676 26 0.054
cardiac muscle cell contraction GO:0086003 7 0.054
regulation of t cell differentiation in thymus GO:0033081 24 0.054
regulation of antimicrobial humoral response GO:0002759 3 0.054
cation homeostasis GO:0055080 212 0.053
protein acylation GO:0043543 64 0.053
Mouse
purine containing compound catabolic process GO:0072523 213 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.053
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.053
regulation of stem cell differentiation GO:2000736 50 0.053
activation of innate immune response GO:0002218 56 0.052
pyramidal neuron migration GO:0021852 1 0.052
nucleocytoplasmic transport GO:0006913 139 0.052
regulation of secretion GO:0051046 274 0.052
chondrocyte differentiation GO:0002062 72 0.052
cellular response to peptide GO:1901653 92 0.052
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.052
ion transmembrane transport GO:0034220 361 0.052
regulation of cell motility GO:2000145 236 0.052
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.051
protein deacylation GO:0035601 36 0.051
activin receptor signaling pathway GO:0032924 18 0.051
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.051
axon target recognition GO:0007412 4 0.051
cell cell signaling involved in kidney development GO:0060995 2 0.051
syncytium formation by plasma membrane fusion GO:0000768 42 0.051
positive regulation of cell migration GO:0030335 109 0.051
gonad development GO:0008406 141 0.051
canonical wnt signaling pathway involved in metanephric kidney development GO:0061290 2 0.050
regulation of actin filament based process GO:0032970 99 0.050
i kappab kinase nf kappab signaling GO:0007249 85 0.050
regulation of organ morphogenesis GO:2000027 144 0.050
inner ear morphogenesis GO:0042472 101 0.050
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.049
cardiac ventricle morphogenesis GO:0003208 50 0.049
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.049
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.049
negative regulation of neuron projection development GO:0010977 50 0.049
columnar cuboidal epithelial cell development GO:0002066 29 0.049
Mouse
cognition GO:0050890 149 0.049
positive regulation of nucleotide metabolic process GO:0045981 114 0.049
somitogenesis GO:0001756 69 0.049
cardiac muscle tissue growth GO:0055017 37 0.048
regulation of cell growth GO:0001558 91 0.048
regulation of defense response GO:0031347 233 0.048
skeletal system development GO:0001501 356 0.048
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.048
multicellular organismal signaling GO:0035637 91 0.048
histone methylation GO:0016571 71 0.048
epithelial cell development GO:0002064 159 0.048
Mouse
peripheral nervous system development GO:0007422 53 0.047
forebrain development GO:0030900 302 0.047
negative regulation of auditory receptor cell differentiation GO:0045608 2 0.047

Klf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.569
cardiovascular system disease DOID:1287 0 0.569
congenital heart disease DOID:1682 0 0.121
heart disease DOID:114 0 0.121
hepatobiliary disease DOID:3118 0 0.053
gastrointestinal system disease DOID:77 0 0.053
liver disease DOID:409 0 0.053