Mus musculus

50 known processes

Ascl3

achaete-scute complex homolog 3 (Drosophila)

(Aliases: Sgn1,MGC129413,MGC129412,bHLHa42)

Ascl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular metal ion homeostasis GO:0006875 151 0.190
g protein coupled receptor signaling pathway GO:0007186 243 0.157
regulation of body fluid levels GO:0050878 162 0.153
calcium ion transport GO:0006816 159 0.149
divalent inorganic cation homeostasis GO:0072507 138 0.127
cellular amine metabolic process GO:0044106 44 0.125
lymphocyte differentiation GO:0030098 242 0.123
cellular ketone metabolic process GO:0042180 84 0.119
metal ion homeostasis GO:0055065 189 0.118
cation homeostasis GO:0055080 212 0.115
cellular calcium ion homeostasis GO:0006874 119 0.098
negative regulation of immune system process GO:0002683 209 0.087
maintenance of location GO:0051235 89 0.086
regulation of cellular amine metabolic process GO:0033238 20 0.085
striated muscle tissue development GO:0014706 293 0.083
divalent inorganic cation transport GO:0072511 178 0.080
cation transport GO:0006812 399 0.076
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
positive regulation of programmed cell death GO:0043068 218 0.069
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.069
positive regulation of cellular amine metabolic process GO:0033240 5 0.066
digestive tract development GO:0048565 190 0.066
Mouse Worm
amine metabolic process GO:0009308 45 0.065
regulation of cell migration GO:0030334 219 0.064
cellular homeostasis GO:0019725 240 0.060
peptidyl amino acid modification GO:0018193 336 0.058
cellular ion homeostasis GO:0006873 165 0.058
regulation of metal ion transport GO:0010959 106 0.058
regulation of leukocyte differentiation GO:1902105 159 0.057
leukocyte differentiation GO:0002521 342 0.056
membrane organization GO:0061024 245 0.052
purine containing compound metabolic process GO:0072521 311 0.051
regulation of cytokine secretion GO:0050707 61 0.050
blood vessel morphogenesis GO:0048514 285 0.049
cytokine secretion GO:0050663 72 0.047
defense response to bacterium GO:0042742 119 0.047
regulation of establishment of protein localization GO:0070201 181 0.046
divalent metal ion transport GO:0070838 172 0.046
negative regulation of lymphocyte activation GO:0051250 91 0.044
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.044
gliogenesis GO:0042063 141 0.044
Mouse
nucleotide metabolic process GO:0009117 332 0.044
cellular amino acid metabolic process GO:0006520 103 0.043
release of sequestered calcium ion into cytosol GO:0051209 42 0.043
organonitrogen compound biosynthetic process GO:1901566 192 0.043
purine nucleotide metabolic process GO:0006163 302 0.043
regulation of lymphocyte differentiation GO:0045619 107 0.042
positive regulation of cell death GO:0010942 224 0.042
Mouse
sequestering of calcium ion GO:0051208 18 0.041
cytokine production GO:0001816 319 0.040
positive regulation of apoptotic process GO:0043065 217 0.040
Mouse
negative regulation of growth GO:0045926 99 0.039
peptidyl tyrosine modification GO:0018212 145 0.039
cellular chemical homeostasis GO:0055082 215 0.039
t cell mediated immunity GO:0002456 50 0.038
cytoplasmic transport GO:0016482 234 0.038
regulation of t cell activation GO:0050863 170 0.038
regulation of multi organism process GO:0043900 111 0.038
regulation of cell motility GO:2000145 236 0.036
calcium ion homeostasis GO:0055074 127 0.036
myeloid cell differentiation GO:0030099 233 0.035
negative regulation of cell development GO:0010721 169 0.034
organic hydroxy compound metabolic process GO:1901615 203 0.034
regulation of homeostatic process GO:0032844 182 0.034
inflammatory response GO:0006954 244 0.034
muscle cell differentiation GO:0042692 261 0.033
rhythmic process GO:0048511 174 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
regulation of cytokine production GO:0001817 266 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
negative regulation of cell activation GO:0050866 111 0.031
t cell activation GO:0042110 289 0.031
negative regulation of adaptive immune response GO:0002820 25 0.031
muscle tissue development GO:0060537 308 0.031
regulation of protein localization GO:0032880 231 0.031
regulation of ion homeostasis GO:2000021 64 0.030
regulation of adaptive immune response GO:0002819 90 0.029
positive regulation of nervous system development GO:0051962 221 0.029
Mouse
interspecies interaction between organisms GO:0044419 83 0.029
regulation of secretion by cell GO:1903530 249 0.028
gonad development GO:0008406 141 0.028
regulation of secretion GO:0051046 274 0.028
regulation of t cell differentiation GO:0045580 83 0.028
cytosolic calcium ion homeostasis GO:0051480 70 0.028
response to inorganic substance GO:0010035 96 0.028
muscle cell development GO:0055001 133 0.028
response to molecule of bacterial origin GO:0002237 143 0.028
negative regulation of secretion by cell GO:1903531 54 0.028
t cell differentiation GO:0030217 174 0.027
oxidation reduction process GO:0055114 342 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
negative regulation of immune effector process GO:0002698 55 0.026
regulation of protein transport GO:0051223 163 0.026
sequestering of metal ion GO:0051238 19 0.026
ossification GO:0001503 216 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
response to extracellular stimulus GO:0009991 127 0.025
positive regulation of ion transport GO:0043270 65 0.025
regulation of calcium ion transport GO:0051924 69 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
multicellular organism growth GO:0035264 161 0.025
Worm
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
circulatory system process GO:0003013 197 0.024
second messenger mediated signaling GO:0019932 73 0.024
response to nutrient levels GO:0031667 109 0.024
tissue homeostasis GO:0001894 115 0.024
transepithelial chloride transport GO:0030321 4 0.024
phagocytosis GO:0006909 66 0.024
positive regulation of cell development GO:0010720 237 0.024
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
regulation of b cell chemotaxis GO:2000537 2 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
connective tissue development GO:0061448 179 0.023
aromatic compound catabolic process GO:0019439 286 0.023
mapk cascade GO:0000165 281 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
regulation of t cell mediated immunity GO:0002709 34 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
homeostasis of number of cells GO:0048872 210 0.022
respiratory system development GO:0060541 190 0.022
Mouse
regulation of intracellular transport GO:0032386 159 0.022
gastrulation GO:0007369 116 0.021
positive regulation of t cell differentiation GO:0045582 52 0.021
response to growth factor GO:0070848 198 0.021
t helper 2 cell cytokine production GO:0035745 4 0.021
cellular lipid metabolic process GO:0044255 323 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
regulation of ion transport GO:0043269 215 0.020
development of primary sexual characteristics GO:0045137 143 0.020
positive regulation of secretion GO:0051047 130 0.020
response to organonitrogen compound GO:0010243 246 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
response to acid chemical GO:0001101 111 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
response to lipopolysaccharide GO:0032496 128 0.020
positive regulation of leukocyte differentiation GO:1902107 86 0.020
negative regulation of protein transport GO:0051224 46 0.020
digestive system development GO:0055123 200 0.020
Mouse Worm
regulation of kinase activity GO:0043549 249 0.020
hepaticobiliary system development GO:0061008 67 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
negative regulation of t cell activation GO:0050868 65 0.019
defense response to other organism GO:0098542 197 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
transmembrane transport GO:0055085 412 0.019
nitrogen compound transport GO:0071705 271 0.019
negative regulation of multi organism process GO:0043901 68 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
b cell differentiation GO:0030183 78 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
digestive tract morphogenesis GO:0048546 147 0.018
cellular response to extracellular stimulus GO:0031668 81 0.018
myeloid cell homeostasis GO:0002262 114 0.018
negative regulation of homeostatic process GO:0032845 71 0.018
positive regulation of lymphocyte differentiation GO:0045621 61 0.018
inter male aggressive behavior GO:0002121 3 0.017
positive regulation of cell migration GO:0030335 109 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
regulation of cellular response to growth factor stimulus GO:0090287 82 0.017
cyclic nucleotide metabolic process GO:0009187 59 0.017
eosinophil migration GO:0072677 3 0.017
negative regulation of t cell mediated immunity GO:0002710 9 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.017
positive regulation of protein modification process GO:0031401 299 0.017
epidermis development GO:0008544 187 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
cellular response to abiotic stimulus GO:0071214 56 0.017
myotube differentiation GO:0014902 105 0.017
cartilage development GO:0051216 140 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
immune effector process GO:0002252 321 0.017
muscle system process GO:0003012 141 0.017
regulation of cell activation GO:0050865 289 0.016
glycerolipid metabolic process GO:0046486 122 0.016
endomembrane system organization GO:0010256 147 0.016
tachykinin receptor signaling pathway GO:0007217 1 0.016
protein localization to organelle GO:0033365 185 0.016
negative regulation of cytokine production GO:0001818 84 0.016
regulation of organelle organization GO:0033043 289 0.016
protein oligomerization GO:0051259 67 0.016
leukocyte proliferation GO:0070661 172 0.016
positive regulation of vasoconstriction GO:0045907 4 0.016
calcium ion transport into cytosol GO:0060402 48 0.016
negative regulation of interleukin 5 production GO:0032714 4 0.016
feeding behavior GO:0007631 62 0.016
intracellular protein transport GO:0006886 204 0.016
positive regulation of proteolysis GO:0045862 85 0.016
dephosphorylation GO:0016311 129 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of actin filament based process GO:0032970 99 0.015
positive regulation of defense response GO:0031349 124 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
male gamete generation GO:0048232 285 0.015
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
positive regulation of protein transport GO:0051222 93 0.015
carbohydrate metabolic process GO:0005975 230 0.015
wound healing GO:0042060 157 0.015
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.015
circadian rhythm GO:0007623 114 0.015
cell fate commitment GO:0045165 210 0.015
Mouse
b cell activation GO:0042113 161 0.015
apoptotic signaling pathway GO:0097190 306 0.015
i kappab kinase nf kappab signaling GO:0007249 85 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
development of primary female sexual characteristics GO:0046545 73 0.015
adaptive immune response GO:0002250 155 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.014
striated muscle cell development GO:0055002 125 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
regulation of protein kinase activity GO:0045859 232 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of response to wounding GO:1903034 189 0.014
notch signaling pathway GO:0007219 71 0.014
Mouse
development of primary male sexual characteristics GO:0046546 88 0.014
endocytosis GO:0006897 168 0.014
liver development GO:0001889 66 0.014
heterocycle catabolic process GO:0046700 280 0.014
alcohol metabolic process GO:0006066 116 0.014
forebrain development GO:0030900 302 0.014
Mouse
macromolecule catabolic process GO:0009057 281 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
erythrocyte differentiation GO:0030218 88 0.014
cell chemotaxis GO:0060326 81 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.014
organophosphate catabolic process GO:0046434 232 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
locomotory behavior GO:0007626 195 0.013
positive regulation of t cell activation GO:0050870 101 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
female sex differentiation GO:0046660 84 0.013
regionalization GO:0003002 337 0.013
Mouse
vascular process in circulatory system GO:0003018 62 0.013
cytosolic calcium ion transport GO:0060401 48 0.013
regulation of hormone levels GO:0010817 211 0.013
glucose homeostasis GO:0042593 128 0.013
ribonucleotide biosynthetic process GO:0009260 59 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
innate immune response GO:0045087 157 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
response to organic cyclic compound GO:0014070 198 0.013
placenta development GO:0001890 140 0.013
Mouse
regulation of cellular catabolic process GO:0031329 242 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
Mouse
asymmetric neuroblast division GO:0055059 1 0.013
chemotaxis GO:0006935 247 0.013
regulation of leukocyte apoptotic process GO:2000106 56 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
response to radiation GO:0009314 165 0.013
lymphocyte proliferation GO:0046651 164 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
reactive oxygen species metabolic process GO:0072593 84 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
protein targeting GO:0006605 143 0.012
regulation of binding GO:0051098 111 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
cellular response to inorganic substance GO:0071241 37 0.012
multicellular organismal signaling GO:0035637 91 0.012
thymocyte migration GO:0072679 2 0.012
positive regulation of eosinophil migration GO:2000418 2 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
wnt signaling pathway GO:0016055 188 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.012
Mouse
negative regulation of leukocyte differentiation GO:1902106 51 0.012
response to inactivity GO:0014854 4 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
response to peptide GO:1901652 136 0.012
anion transport GO:0006820 177 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
positive regulation of thymocyte migration GO:2000412 2 0.012
positive regulation of interferon alpha production GO:0032727 4 0.012
small molecule biosynthetic process GO:0044283 132 0.012
epithelial tube morphogenesis GO:0060562 303 0.011
protein ubiquitination GO:0016567 171 0.011
leukocyte apoptotic process GO:0071887 71 0.011
sphingolipid metabolic process GO:0006665 45 0.011
nuclear transport GO:0051169 139 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
positive regulation of cytokine production GO:0001819 174 0.011
chromatin modification GO:0016568 187 0.011
regulation of hydrolase activity GO:0051336 246 0.011
cardiac muscle tissue development GO:0048738 130 0.011
plasma membrane organization GO:0007009 90 0.011
cellular response to external stimulus GO:0071496 88 0.011
regulation of t helper 2 cell cytokine production GO:2000551 3 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
membrane lipid metabolic process GO:0006643 53 0.011
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.011
negative regulation of muscle cell differentiation GO:0051148 33 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.011
negative regulation of ossification GO:0030279 49 0.011
blood circulation GO:0008015 195 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
purine containing compound catabolic process GO:0072523 213 0.011
carbohydrate homeostasis GO:0033500 128 0.011
membrane lipid biosynthetic process GO:0046467 32 0.011
sensory perception of chemical stimulus GO:0007606 51 0.011
establishment of organelle localization GO:0051656 122 0.011
positive regulation of transferase activity GO:0051347 167 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
negative regulation of nervous system development GO:0051961 156 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
ion transmembrane transport GO:0034220 361 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
skin development GO:0043588 220 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
anatomical structure homeostasis GO:0060249 145 0.010
stem cell proliferation GO:0072089 117 0.010
Mouse
hormone secretion GO:0046879 128 0.010
peptide transport GO:0015833 133 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
fat cell differentiation GO:0045444 160 0.010
neuronal action potential GO:0019228 54 0.010
coagulation GO:0050817 78 0.010

Ascl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.016
musculoskeletal system disease DOID:17 0 0.010