Mus musculus

0 known processes

Klhl35

kelch-like 35 (Drosophila)

(Aliases: 2810406K13Rik)

Klhl35 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.147
skeletal system development GO:0001501 356 0.127
epithelial tube morphogenesis GO:0060562 303 0.099
gland development GO:0048732 330 0.078
skeletal system morphogenesis GO:0048705 203 0.077
embryonic organ morphogenesis GO:0048562 276 0.072
myeloid cell differentiation GO:0030099 233 0.066
forebrain development GO:0030900 302 0.066
blood vessel morphogenesis GO:0048514 285 0.062
transmembrane transport GO:0055085 412 0.059
sensory organ morphogenesis GO:0090596 242 0.055
renal system development GO:0072001 225 0.055
ion transmembrane transport GO:0034220 361 0.054
regulation of secretion GO:0051046 274 0.053
urogenital system development GO:0001655 261 0.052
homeostasis of number of cells GO:0048872 210 0.050
cell type specific apoptotic process GO:0097285 268 0.047
stem cell differentiation GO:0048863 268 0.047
bundle of his development GO:0003166 4 0.047
cartilage development GO:0051216 140 0.045
regulation of neuron differentiation GO:0045664 281 0.045
developmental growth involved in morphogenesis GO:0060560 138 0.044
stem cell development GO:0048864 219 0.043
lymphocyte differentiation GO:0030098 242 0.043
epithelial cell development GO:0002064 159 0.042
muscle cell development GO:0055001 133 0.040
somatotropin secreting cell differentiation GO:0060126 4 0.039
striated muscle tissue development GO:0014706 293 0.038
inorganic ion transmembrane transport GO:0098660 234 0.038
negative regulation of nervous system development GO:0051961 156 0.038
dendrite development GO:0016358 115 0.038
organelle assembly GO:0070925 177 0.037
pancreatic pp cell differentiation GO:0003312 2 0.037
muscle tissue development GO:0060537 308 0.036
regulation of neuron death GO:1901214 134 0.036
regulation of cell adhesion GO:0030155 154 0.036
regulation of organ morphogenesis GO:2000027 144 0.035
negative regulation of immune system process GO:0002683 209 0.035
ear morphogenesis GO:0042471 118 0.035
angiogenesis GO:0001525 201 0.035
axonogenesis GO:0007409 274 0.034
bmp signaling pathway GO:0030509 93 0.034
camera type eye development GO:0043010 266 0.033
sensory perception GO:0007600 245 0.033
locomotory behavior GO:0007626 195 0.033
positive regulation of cell development GO:0010720 237 0.033
extracellular structure organization GO:0043062 148 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.032
digestive tract development GO:0048565 190 0.032
spleen development GO:0048536 39 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
kidney development GO:0001822 213 0.031
cation transmembrane transport GO:0098655 266 0.031
t cell activation GO:0042110 289 0.030
pancreatic pp cell fate commitment GO:0003329 2 0.030
connective tissue development GO:0061448 179 0.030
developmental maturation GO:0021700 193 0.030
ossification GO:0001503 216 0.030
regulation of epithelial cell proliferation GO:0050678 141 0.029
muscle cell differentiation GO:0042692 261 0.029
wnt signaling pathway GO:0016055 188 0.029
b cell activation GO:0042113 161 0.029
dna metabolic process GO:0006259 303 0.029
his purkinje system development GO:0003164 4 0.028
cellular ketone metabolic process GO:0042180 84 0.028
cell adhesion GO:0007155 329 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
determination of left right symmetry GO:0007368 80 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
carbohydrate homeostasis GO:0033500 128 0.027
skeletal muscle organ development GO:0060538 163 0.027
leukocyte differentiation GO:0002521 342 0.027
mesenchyme development GO:0060485 152 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
response to organonitrogen compound GO:0010243 246 0.026
spermatogenesis GO:0007283 284 0.026
b cell differentiation GO:0030183 78 0.025
mesoderm development GO:0007498 100 0.025
response to organic cyclic compound GO:0014070 198 0.025
cell fate commitment GO:0045165 210 0.025
digestive system development GO:0055123 200 0.025
regulation of secretion by cell GO:1903530 249 0.025
endocrine system development GO:0035270 98 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
organelle fission GO:0048285 170 0.024
digestive tract morphogenesis GO:0048546 147 0.024
cerebral cortex development GO:0021987 86 0.024
negative regulation of cell development GO:0010721 169 0.024
branching morphogenesis of an epithelial tube GO:0048754 159 0.024
lung development GO:0030324 164 0.024
morphogenesis of a branching epithelium GO:0061138 193 0.024
detection of stimulus GO:0051606 84 0.024
sensory perception of sound GO:0007605 97 0.024
morphogenesis of a branching structure GO:0001763 203 0.024
positive regulation of apoptotic process GO:0043065 217 0.023
ear development GO:0043583 200 0.023
skeletal muscle cell differentiation GO:0035914 66 0.023
epithelial cell proliferation GO:0050673 174 0.023
retina development in camera type eye GO:0060041 119 0.023
lateral inhibition GO:0046331 1 0.023
epidermis development GO:0008544 187 0.023
regulation of cell motility GO:2000145 236 0.023
response to growth factor GO:0070848 198 0.023
male gamete generation GO:0048232 285 0.022
cell maturation GO:0048469 127 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
actin cytoskeleton organization GO:0030036 220 0.022
diencephalon development GO:0021536 63 0.022
regulation of ion transport GO:0043269 215 0.022
myeloid leukocyte differentiation GO:0002573 119 0.022
mesenchymal cell differentiation GO:0048762 107 0.022
cellular amino acid metabolic process GO:0006520 103 0.021
respiratory system development GO:0060541 190 0.021
neuron apoptotic process GO:0051402 142 0.021
placenta development GO:0001890 140 0.021
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.021
positive regulation of transcription via serum response element binding GO:0010735 1 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
synaptic transmission GO:0007268 329 0.021
regulation of canonical wnt signaling pathway GO:0060828 82 0.021
cardiac chamber development GO:0003205 108 0.020
left right pattern formation GO:0060972 23 0.020
his purkinje system cell differentiation GO:0060932 2 0.020
chemotaxis GO:0006935 247 0.020
inner ear morphogenesis GO:0042472 101 0.020
ventral spinal cord interneuron differentiation GO:0021514 16 0.020
positive regulation of cell death GO:0010942 224 0.020
multi multicellular organism process GO:0044706 109 0.020
regulation of cell projection organization GO:0031344 206 0.020
globus pallidus development GO:0021759 2 0.020
sperm motility GO:0030317 47 0.020
negative regulation of wnt signaling pathway GO:0030178 73 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
regulation of cardioblast differentiation GO:0051890 3 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
regulation of neural retina development GO:0061074 3 0.020
cardiocyte differentiation GO:0035051 87 0.020
bone development GO:0060348 120 0.020
cardiac muscle cell differentiation GO:0055007 69 0.020
canonical wnt signaling pathway GO:0060070 130 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
development of primary sexual characteristics GO:0045137 143 0.019
cytoplasmic transport GO:0016482 234 0.019
pulmonary myocardium development GO:0003350 3 0.019
regulation of organelle organization GO:0033043 289 0.019
carbohydrate metabolic process GO:0005975 230 0.019
telencephalon development GO:0021537 186 0.019
cardiac ventricle development GO:0003231 83 0.019
chromatin organization GO:0006325 206 0.019
interleukin 8 secretion GO:0072606 3 0.019
mesenchymal cell development GO:0014031 93 0.019
glucose homeostasis GO:0042593 128 0.019
microtubule based process GO:0007017 236 0.019
paraxial mesodermal cell fate commitment GO:0048343 2 0.018
cellular response to lipid GO:0071396 145 0.018
septum transversum development GO:0003343 2 0.018
peripheral nervous system development GO:0007422 53 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.018
atrial cardiac muscle cell development GO:0055014 2 0.018
regulation of neuron projection development GO:0010975 169 0.018
anatomical structure homeostasis GO:0060249 145 0.018
mitotic cell cycle GO:0000278 195 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
purine containing compound metabolic process GO:0072521 311 0.018
cellular amine metabolic process GO:0044106 44 0.017
cardiac muscle tissue development GO:0048738 130 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
amine metabolic process GO:0009308 45 0.017
t cell differentiation GO:0030217 174 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
inflammatory response GO:0006954 244 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
cellular chemical homeostasis GO:0055082 215 0.017
neuroblast differentiation GO:0014016 2 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
nephron epithelium development GO:0072009 92 0.017
heart morphogenesis GO:0003007 178 0.017
regulation of myeloid cell differentiation GO:0045637 96 0.017
nephron development GO:0072006 109 0.016
leukocyte migration GO:0050900 124 0.016
smoothened signaling pathway GO:0007224 105 0.016
positive regulation of nervous system development GO:0051962 221 0.016
clara cell differentiation GO:0060486 4 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
chondrocyte differentiation GO:0002062 72 0.016
paraxial mesodermal cell differentiation GO:0048342 2 0.016
regulation of system process GO:0044057 200 0.016
leukocyte proliferation GO:0070661 172 0.016
regulation of voltage gated calcium channel activity GO:1901385 4 0.016
ectoderm formation GO:0001705 3 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
regulation of cell cycle GO:0051726 281 0.016
oxidation reduction process GO:0055114 342 0.016
pancreas development GO:0031016 57 0.016
kidney epithelium development GO:0072073 121 0.016
regulation of wnt signaling pathway GO:0030111 123 0.015
neuron death GO:0070997 154 0.015
mitotic cell cycle process GO:1903047 159 0.015
cell growth GO:0016049 130 0.015
macromolecule catabolic process GO:0009057 281 0.015
hepaticobiliary system development GO:0061008 67 0.015
cell recognition GO:0008037 83 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
stem cell proliferation GO:0072089 117 0.015
regulation of protein kinase activity GO:0045859 232 0.015
regulation of neural precursor cell proliferation GO:2000177 70 0.015
nephron tubule development GO:0072080 84 0.015
trachea cartilage morphogenesis GO:0060535 4 0.015
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.015
cardiac chamber morphogenesis GO:0003206 93 0.015
mitochondrion organization GO:0007005 134 0.015
ventricular cardiac myofibril assembly GO:0055005 3 0.015
cellular homeostasis GO:0019725 240 0.015
renal tubule development GO:0061326 87 0.015
embryonic heart tube development GO:0035050 65 0.015
glycoprotein metabolic process GO:0009100 116 0.015
ventral spinal cord interneuron fate determination GO:0060580 1 0.015
cardiac pacemaker cell fate commitment GO:0060927 1 0.015
regulation of glial cell differentiation GO:0045685 41 0.015
respiratory tube development GO:0030323 167 0.015
negative regulation of neuron differentiation GO:0045665 101 0.015
regulation of stem cell proliferation GO:0072091 78 0.015
plasma cell differentiation GO:0002317 3 0.015
response to acid chemical GO:0001101 111 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
male gonad development GO:0008584 88 0.014
cell differentiation in spinal cord GO:0021515 53 0.014
regulation of transmembrane transport GO:0034762 128 0.014
muscle tissue morphogenesis GO:0060415 53 0.014
membrane organization GO:0061024 245 0.014
dna methylation involved in gamete generation GO:0043046 15 0.014
spermatid differentiation GO:0048515 115 0.014
rho protein signal transduction GO:0007266 32 0.014
positive regulation of cell cycle GO:0045787 92 0.014
embryonic heart tube morphogenesis GO:0003143 51 0.014
germ cell development GO:0007281 185 0.014
heterocycle catabolic process GO:0046700 280 0.014
neuromuscular process GO:0050905 99 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
cardiac ventricle morphogenesis GO:0003208 50 0.014
nuclear division GO:0000280 158 0.014
mrna metabolic process GO:0016071 84 0.014
cerebral cortex cell migration GO:0021795 44 0.014
regulation of cardiac chamber morphogenesis GO:1901219 2 0.014
pituitary gland development GO:0021983 38 0.014
gastrulation GO:0007369 116 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
oocyte axis specification GO:0007309 2 0.014
mesangial cell differentiation GO:0072007 4 0.014
apoptotic signaling pathway GO:0097190 306 0.014
pallium development GO:0021543 120 0.014
mesodermal cell migration GO:0008078 4 0.014
leukocyte homeostasis GO:0001776 79 0.014
cardiac muscle tissue morphogenesis GO:0055008 44 0.014
mammary gland epithelium development GO:0061180 65 0.014
neural precursor cell proliferation GO:0061351 121 0.014
neuron projection guidance GO:0097485 141 0.013
astrocyte fate commitment GO:0060018 4 0.013
embryonic skeletal system development GO:0048706 120 0.013
rna interference GO:0016246 2 0.013
limb development GO:0060173 166 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
axon guidance GO:0007411 141 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
chromatin modification GO:0016568 187 0.013
regulation of response to wounding GO:1903034 189 0.013
spinal cord development GO:0021510 81 0.013
endocrine pancreas development GO:0031018 29 0.013
cytokine production GO:0001816 319 0.013
regulation of stem cell differentiation GO:2000736 50 0.013
tongue development GO:0043586 18 0.013
interleukin 8 production GO:0032637 4 0.013
liver development GO:0001889 66 0.013
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.013
cardiac cell development GO:0055006 41 0.013
forebrain cell migration GO:0021885 58 0.013
pancreatic a cell fate commitment GO:0003326 2 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
pharynx development GO:0060465 1 0.013
cellular response to monosaccharide stimulus GO:0071326 47 0.013
atrioventricular node cell development GO:0060928 2 0.013
adult behavior GO:0030534 135 0.013
purkinje myocyte differentiation GO:0003168 1 0.013
tissue homeostasis GO:0001894 115 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of cell migration GO:0030334 219 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
atrial cardiac muscle cell differentiation GO:0055011 2 0.013
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.012
neural tube development GO:0021915 160 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
menarche GO:0042696 1 0.012
anion transport GO:0006820 177 0.012
regulation of hormone levels GO:0010817 211 0.012
rhythmic process GO:0048511 174 0.012
detection of molecule of bacterial origin GO:0032490 2 0.012
epithelial tube formation GO:0072175 130 0.012
mesoderm formation GO:0001707 62 0.012
ureteric bud development GO:0001657 94 0.012
regulation of angiogenesis GO:0045765 81 0.012
oocyte construction GO:0007308 2 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
regulation of vasculature development GO:1901342 88 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
developmental programmed cell death GO:0010623 41 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
skin development GO:0043588 220 0.012
negative regulation of organelle organization GO:0010639 90 0.012
telencephalon cell migration GO:0022029 55 0.012
cell activation involved in immune response GO:0002263 126 0.012
sensory system development GO:0048880 3 0.012
heart contraction GO:0060047 93 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
gliogenesis GO:0042063 141 0.012
formation of primary germ layer GO:0001704 77 0.012
cellular glucose homeostasis GO:0001678 52 0.012
aromatic compound catabolic process GO:0019439 286 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
regulation of ossification GO:0030278 112 0.012
hormone secretion GO:0046879 128 0.012
atrioventricular node cell fate commitment GO:0060929 1 0.012
respiratory gaseous exchange GO:0007585 43 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
rna processing GO:0006396 105 0.012
positive regulation of cell migration GO:0030335 109 0.012
mitotic chromosome condensation GO:0007076 1 0.011
atrioventricular node cell differentiation GO:0060922 2 0.011
somatotropin secreting cell development GO:0060133 2 0.011
peptide transport GO:0015833 133 0.011
mechanoreceptor differentiation GO:0042490 67 0.011
ventral spinal cord development GO:0021517 48 0.011
divalent metal ion transport GO:0070838 172 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
ras protein signal transduction GO:0007265 77 0.011
outflow tract morphogenesis GO:0003151 53 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
spermatid development GO:0007286 108 0.011
pirna metabolic process GO:0034587 12 0.011
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.011
spinal cord motor neuron differentiation GO:0021522 35 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
lipid transport GO:0006869 98 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
positive regulation of transcription by glucose GO:0046016 3 0.011
epithelium migration GO:0090132 63 0.011
glial cell differentiation GO:0010001 131 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
protein ubiquitination GO:0016567 171 0.011
nucleoside metabolic process GO:0009116 246 0.011
maintenance of location GO:0051235 89 0.011
epithelial to mesenchymal transition GO:0001837 47 0.011
positive regulation of protein modification process GO:0031401 299 0.011
muscle system process GO:0003012 141 0.011
negative regulation of molecular function GO:0044092 258 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
mesoderm morphogenesis GO:0048332 64 0.011
positive regulation of cell motility GO:2000147 116 0.011
regulation of cytokine production GO:0001817 266 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
cellular protein catabolic process GO:0044257 155 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
mrna processing GO:0006397 63 0.011
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
forebrain regionalization GO:0021871 25 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
regulation of cellular component size GO:0032535 121 0.011
regulation of retina development in camera type eye GO:1902866 3 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
meiotic cell cycle GO:0051321 122 0.010
macromolecule methylation GO:0043414 120 0.010
negative regulation of myeloid cell differentiation GO:0045638 38 0.010
neuron projection extension GO:1990138 64 0.010
multicellular organism growth GO:0035264 161 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
regulation of membrane potential GO:0042391 192 0.010
mitochondrion distribution GO:0048311 4 0.010
extracellular matrix organization GO:0030198 147 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
alcohol metabolic process GO:0006066 116 0.010
regulation of vascular wound healing GO:0061043 2 0.010
cation transport GO:0006812 399 0.010
tissue remodeling GO:0048771 102 0.010
cellular protein complex assembly GO:0043623 116 0.010
myeloid cell homeostasis GO:0002262 114 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
regulation of cartilage development GO:0061035 44 0.010
wound healing GO:0042060 157 0.010
multi organism behavior GO:0051705 62 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
intracellular protein transport GO:0006886 204 0.010
male sex differentiation GO:0046661 109 0.010
sequestering of metal ion GO:0051238 19 0.010
methylation GO:0032259 134 0.010
columnar cuboidal epithelial cell development GO:0002066 29 0.010

Klhl35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
bone disease DOID:0080001 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010