Mus musculus

0 known processes

Hmgcs1

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

(Aliases: B130032C06Rik,MGC36662,MGC98430)

Hmgcs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular alcohol biosynthetic process GO:0044108 3 1.000
sterol metabolic process GO:0016125 58 1.000
cholesterol biosynthetic process GO:0006695 15 0.998
lipid biosynthetic process GO:0008610 179 0.997
small molecule biosynthetic process GO:0044283 132 0.995
alcohol biosynthetic process GO:0046165 43 0.988
cellular alcohol metabolic process GO:0044107 3 0.983
alcohol metabolic process GO:0006066 116 0.981
sterol biosynthetic process GO:0016126 17 0.945
cholesterol metabolic process GO:0008203 56 0.908
isoprenoid biosynthetic process GO:0008299 9 0.899
steroid metabolic process GO:0008202 119 0.856
oxidation reduction process GO:0055114 342 0.828
cellular lipid metabolic process GO:0044255 323 0.819
organic hydroxy compound metabolic process GO:1901615 203 0.756
response to stilbenoid GO:0035634 22 0.711
steroid biosynthetic process GO:0006694 47 0.697
long chain fatty acid biosynthetic process GO:0042759 5 0.520
fatty acid elongation GO:0030497 3 0.490
organic hydroxy compound biosynthetic process GO:1901617 77 0.472
sphingolipid metabolic process GO:0006665 45 0.469
long chain fatty acid metabolic process GO:0001676 26 0.438
cellular biogenic amine metabolic process GO:0006576 28 0.399
organonitrogen compound biosynthetic process GO:1901566 192 0.368
fatty acid elongation unsaturated fatty acid GO:0019368 2 0.282
sphingolipid biosynthetic process GO:0030148 26 0.259
lipid modification GO:0030258 65 0.236
sterol transmembrane transport GO:0035382 2 0.190
rhodopsin mediated signaling pathway GO:0016056 4 0.187
liver development GO:0001889 66 0.162
fatty acid metabolic process GO:0006631 121 0.157
demethylation GO:0070988 23 0.154
lipid transport GO:0006869 98 0.150
monocarboxylic acid biosynthetic process GO:0072330 61 0.147
mating behavior sex discrimination GO:0048047 1 0.144
glutamate biosynthetic process GO:0006537 2 0.143
monocarboxylic acid metabolic process GO:0032787 191 0.135
regulation of phospholipid catabolic process GO:0060696 2 0.123
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.121
small molecule catabolic process GO:0044282 71 0.120
carboxylic acid biosynthetic process GO:0046394 86 0.109
organic acid biosynthetic process GO:0016053 86 0.107
response to radiation GO:0009314 165 0.097
adaptation of rhodopsin mediated signaling GO:0016062 2 0.094
spermatid differentiation GO:0048515 115 0.092
regulation of cellular amine metabolic process GO:0033238 20 0.090
endocytosis GO:0006897 168 0.088
regulation of lipid metabolic process GO:0019216 118 0.084
sterol transport GO:0015918 38 0.081
very long chain fatty acid biosynthetic process GO:0042761 2 0.075
negative regulation of multi organism process GO:0043901 68 0.074
alpha amino acid biosynthetic process GO:1901607 15 0.073
lipid localization GO:0010876 126 0.071
ribonucleotide metabolic process GO:0009259 291 0.071
response to nutrient levels GO:0031667 109 0.070
cellular amino acid metabolic process GO:0006520 103 0.070
cellular amino acid biosynthetic process GO:0008652 22 0.067
triglyceride biosynthetic process GO:0019432 17 0.066
neutral lipid biosynthetic process GO:0046460 18 0.065
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.064
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.063
cellular ketone metabolic process GO:0042180 84 0.062
negative regulation of intracellular signal transduction GO:1902532 167 0.059
negative regulation of molecular function GO:0044092 258 0.059
purine nucleotide metabolic process GO:0006163 302 0.056
fatty acid biosynthetic process GO:0006633 41 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.054
microtubule cytoskeleton organization GO:0000226 157 0.053
coenzyme biosynthetic process GO:0009108 23 0.053
glycosyl compound metabolic process GO:1901657 246 0.050
regulation of phospholipid biosynthetic process GO:0071071 3 0.050
tricarboxylic acid metabolic process GO:0072350 5 0.048
response to organic cyclic compound GO:0014070 198 0.048
phospholipid catabolic process GO:0009395 5 0.047
organic hydroxy compound catabolic process GO:1901616 25 0.047
regulation of triglyceride metabolic process GO:0090207 17 0.047
nucleotide metabolic process GO:0009117 332 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
purine nucleoside metabolic process GO:0042278 241 0.044
ras protein signal transduction GO:0007265 77 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
ribonucleoside metabolic process GO:0009119 245 0.043
response to phenylpropanoid GO:0080184 22 0.041
response to peptide GO:1901652 136 0.041
ribose phosphate metabolic process GO:0019693 291 0.039
positive regulation of lipid metabolic process GO:0045834 40 0.039
cholesterol import GO:0070508 2 0.038
small gtpase mediated signal transduction GO:0007264 97 0.038
positive regulation of mapk cascade GO:0043410 170 0.038
positive regulation of growth GO:0045927 104 0.037
locomotory behavior GO:0007626 195 0.037
gland development GO:0048732 330 0.037
response to extracellular stimulus GO:0009991 127 0.037
response to organonitrogen compound GO:0010243 246 0.037
hormone secretion GO:0046879 128 0.035
cellular amine metabolic process GO:0044106 44 0.035
regulation of organelle organization GO:0033043 289 0.034
positive regulation of triglyceride metabolic process GO:0090208 9 0.034
regulation of hormone levels GO:0010817 211 0.033
regulation of vesicle mediated transport GO:0060627 139 0.033
organophosphate catabolic process GO:0046434 232 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
forebrain development GO:0030900 302 0.031
response to monosaccharide GO:0034284 67 0.031
glutamate metabolic process GO:0006536 9 0.030
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
nucleoside metabolic process GO:0009116 246 0.029
regulation of cytoskeleton organization GO:0051493 122 0.028
nucleoside bisphosphate biosynthetic process GO:0033866 6 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
cholesterol homeostasis GO:0042632 44 0.028
cellular ketone body metabolic process GO:0046950 3 0.027
skin development GO:0043588 220 0.027
positive regulation of cholesterol biosynthetic process GO:0045542 3 0.027
amine metabolic process GO:0009308 45 0.027
pallium development GO:0021543 120 0.027
organonitrogen compound catabolic process GO:1901565 264 0.026
cellular response to carbohydrate stimulus GO:0071322 50 0.026
maintenance of location GO:0051235 89 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
multicellular organism growth GO:0035264 161 0.026
oocyte construction GO:0007308 2 0.026
positive regulation of creb transcription factor activity GO:0032793 4 0.025
positive regulation of transferase activity GO:0051347 167 0.024
ethanolamine containing compound metabolic process GO:0042439 18 0.024
positive regulation of protein modification process GO:0031401 299 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
detection of abiotic stimulus GO:0009582 60 0.024
regulation of secretion GO:0051046 274 0.024
spermatid development GO:0007286 108 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
negative regulation of growth GO:0045926 99 0.023
cellularization GO:0007349 1 0.023
sterol homeostasis GO:0055092 45 0.023
ribonucleotide biosynthetic process GO:0009260 59 0.023
negative regulation of synapse assembly GO:0051964 3 0.022
actin filament organization GO:0007015 113 0.022
asymmetric stem cell division GO:0098722 3 0.022
male gamete generation GO:0048232 285 0.022
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.022
molting cycle GO:0042303 90 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
protein catabolic process GO:0030163 221 0.021
mapk cascade GO:0000165 281 0.021
glycerolipid metabolic process GO:0046486 122 0.021
maternal determination of anterior posterior axis embryo GO:0008358 2 0.021
ribose phosphate biosynthetic process GO:0046390 59 0.021
response to light stimulus GO:0009416 135 0.021
rho protein signal transduction GO:0007266 32 0.021
positive regulation of cell projection organization GO:0031346 95 0.021
regulation of cell motility GO:2000145 236 0.020
establishment or maintenance of cell polarity GO:0007163 86 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
regulation of transferase activity GO:0051338 263 0.020
response to oxidative stress GO:0006979 123 0.020
mitochondrion organization GO:0007005 134 0.020
organic acid catabolic process GO:0016054 51 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.019
gtp catabolic process GO:0006184 143 0.019
rhythmic process GO:0048511 174 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
neutral lipid metabolic process GO:0006638 57 0.019
response to steroid hormone GO:0048545 56 0.019
anion transport GO:0006820 177 0.019
response to yeast GO:0001878 6 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
defense response to bacterium GO:0042742 119 0.019
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.018
asymmetric neuroblast division GO:0055059 1 0.018
response to peptide hormone GO:0043434 127 0.018
lipid catabolic process GO:0016042 69 0.018
cellular response to extracellular stimulus GO:0031668 81 0.018
receptor biosynthetic process GO:0032800 3 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
insulin secretion GO:0030073 89 0.018
negative regulation of nervous system development GO:0051961 156 0.018
actin cytoskeleton organization GO:0030036 220 0.018
negative regulation of cholesterol transport GO:0032375 4 0.018
dna metabolic process GO:0006259 303 0.018
cell division GO:0051301 120 0.017
spermatogenesis GO:0007283 284 0.017
intracellular mrna localization GO:0008298 4 0.017
cellular respiration GO:0045333 38 0.017
cellular protein complex assembly GO:0043623 116 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.017
microtubule based process GO:0007017 236 0.017
cytoplasmic transport GO:0016482 234 0.017
sensory organ morphogenesis GO:0090596 242 0.017
regulation of membrane potential GO:0042391 192 0.017
lung development GO:0030324 164 0.017
fatty acid beta oxidation GO:0006635 16 0.017
cellular transition metal ion homeostasis GO:0046916 32 0.017
regulation of cell migration GO:0030334 219 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
iron ion homeostasis GO:0055072 36 0.016
cell junction maintenance GO:0034331 4 0.016
genitalia development GO:0048806 37 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
respiratory tube development GO:0030323 167 0.016
aromatic compound catabolic process GO:0019439 286 0.016
positive regulation of cell development GO:0010720 237 0.016
carboxylic acid catabolic process GO:0046395 51 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
cellular chemical homeostasis GO:0055082 215 0.016
nucleotide catabolic process GO:0009166 217 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
positive regulation of cell adhesion GO:0045785 80 0.016
positive regulation of cell motility GO:2000147 116 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
retrograde transport endosome to golgi GO:0042147 2 0.016
ion transmembrane transport GO:0034220 361 0.016
regulation of protein complex assembly GO:0043254 83 0.016
regulation of neuron projection development GO:0010975 169 0.015
energy derivation by oxidation of organic compounds GO:0015980 77 0.015
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.015
purine containing compound metabolic process GO:0072521 311 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
membrane organization GO:0061024 245 0.015
muscle system process GO:0003012 141 0.015
meiotic cell cycle GO:0051321 122 0.015
fat cell differentiation GO:0045444 160 0.015
cellular lipid catabolic process GO:0044242 52 0.015
regulation of cell cycle GO:0051726 281 0.015
regulation of kinase activity GO:0043549 249 0.015
acylglycerol metabolic process GO:0006639 55 0.015
membrane lipid metabolic process GO:0006643 53 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
endomembrane system organization GO:0010256 147 0.015
protein localization to membrane GO:0072657 108 0.015
cellular response to lipid GO:0071396 145 0.015
formation of organ boundary GO:0010160 1 0.015
low density lipoprotein particle clearance GO:0034383 8 0.015
regulation of neuron differentiation GO:0045664 281 0.015
regulation of multi organism process GO:0043900 111 0.015
cell growth GO:0016049 130 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
transmission of nerve impulse GO:0019226 76 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
oocyte axis specification GO:0007309 2 0.014
lipid homeostasis GO:0055088 63 0.014
thioester metabolic process GO:0035383 19 0.014
smoothened signaling pathway GO:0007224 105 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of ion transport GO:0043269 215 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
regulation of cell projection organization GO:0031344 206 0.014
response to inorganic substance GO:0010035 96 0.014
triglyceride metabolic process GO:0006641 51 0.014
multicellular organismal signaling GO:0035637 91 0.014
carbohydrate homeostasis GO:0033500 128 0.014
stem cell development GO:0048864 219 0.014
positive regulation of nervous system development GO:0051962 221 0.014
cofactor biosynthetic process GO:0051188 41 0.014
nucleotide biosynthetic process GO:0009165 78 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
stem cell differentiation GO:0048863 268 0.014
glutamine family amino acid metabolic process GO:0009064 15 0.014
dicarboxylic acid biosynthetic process GO:0043650 5 0.014
regulation of cellular component biogenesis GO:0044087 181 0.013
compound eye development GO:0048749 1 0.013
establishment of protein localization to membrane GO:0090150 54 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
metal ion homeostasis GO:0055065 189 0.013
ameboidal type cell migration GO:0001667 128 0.013
tissue migration GO:0090130 68 0.013
telencephalon development GO:0021537 186 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
regulation of mapk cascade GO:0043408 248 0.013
negative regulation of protein modification process GO:0031400 163 0.013
acyl coa biosynthetic process GO:0071616 7 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
cation transmembrane transport GO:0098655 266 0.013
regulation of exocytosis GO:0017157 61 0.013
blood vessel morphogenesis GO:0048514 285 0.013
activation of adenylate cyclase activity GO:0007190 4 0.013
innate immune response GO:0045087 157 0.013
regulation of cellular component size GO:0032535 121 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.013
regulation of lipid storage GO:0010883 20 0.013
peptide metabolic process GO:0006518 46 0.013
phosphorylated carbohydrate dephosphorylation GO:0046838 4 0.013
wnt signaling pathway GO:0016055 188 0.013
neuronal action potential GO:0019228 54 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
cellular amide metabolic process GO:0043603 58 0.013
nucleoside biosynthetic process GO:0009163 21 0.012
positive regulation of secretion GO:0051047 130 0.012
histone modification GO:0016570 159 0.012
dicarboxylic acid metabolic process GO:0043648 18 0.012
development of primary sexual characteristics GO:0045137 143 0.012
regulation of receptor biosynthetic process GO:0010869 2 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
amide transport GO:0042886 138 0.012
response to starvation GO:0042594 65 0.012
positive regulation of steroid biosynthetic process GO:0010893 4 0.012
cellular response to external stimulus GO:0071496 88 0.012
limbic system development GO:0021761 72 0.012
organelle disassembly GO:1903008 2 0.012
positive regulation of cholesterol storage GO:0010886 3 0.012
isoprenoid metabolic process GO:0006720 29 0.012
defense response to gram positive bacterium GO:0050830 50 0.012
fatty acid oxidation GO:0019395 28 0.012
cellular homeostasis GO:0019725 240 0.012
mrna metabolic process GO:0016071 84 0.012
female sex differentiation GO:0046660 84 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
associative learning GO:0008306 61 0.012
transmembrane transport GO:0055085 412 0.012
glucose homeostasis GO:0042593 128 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.012
regulation of defense response GO:0031347 233 0.012
cell fate determination involved in pattern specification GO:0060582 1 0.012
regulation of transmembrane transport GO:0034762 128 0.012
regulation of actin filament based process GO:0032970 99 0.012
positive regulation of triglyceride biosynthetic process GO:0010867 6 0.012
osteoclast differentiation GO:0030316 62 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of homeostatic process GO:0032844 182 0.012
nitrogen compound transport GO:0071705 271 0.012
nucleoside catabolic process GO:0009164 206 0.012
response to insulin GO:0032868 100 0.012
carbon catabolite regulation of transcription GO:0045990 4 0.012
growth involved in symbiotic interaction GO:0044110 23 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
organic acid transport GO:0015849 101 0.012
glutathione metabolic process GO:0006749 16 0.011
cofactor metabolic process GO:0051186 80 0.011
neural precursor cell proliferation GO:0061351 121 0.011
synapse organization GO:0050808 125 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.011
sensory perception GO:0007600 245 0.011
synaptic transmission GO:0007268 329 0.011
organic hydroxy compound transport GO:0015850 93 0.011
learning GO:0007612 98 0.011
purine containing compound catabolic process GO:0072523 213 0.011
germ cell development GO:0007281 185 0.011
urogenital system development GO:0001655 261 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
exocytosis GO:0006887 121 0.011
learning or memory GO:0007611 148 0.011
angiogenesis GO:0001525 201 0.011
developmental cell growth GO:0048588 84 0.011
cell cell junction organization GO:0045216 72 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
chemotaxis GO:0006935 247 0.011
camera type eye development GO:0043010 266 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
lipid oxidation GO:0034440 29 0.011
nadph regeneration GO:0006740 2 0.011
action potential GO:0001508 78 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
microtubule based movement GO:0007018 84 0.011
tissue homeostasis GO:0001894 115 0.011
cellular protein complex disassembly GO:0043624 36 0.011
localization within membrane GO:0051668 4 0.011
regulation of protein kinase activity GO:0045859 232 0.011
macromolecule deacylation GO:0098732 37 0.011
response to acid chemical GO:0001101 111 0.011
inter male aggressive behavior GO:0002121 3 0.011
very long chain fatty acid metabolic process GO:0000038 8 0.011
organelle fission GO:0048285 170 0.011
cell substrate adhesion GO:0031589 130 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
macromolecule catabolic process GO:0009057 281 0.011
peptidyl amino acid modification GO:0018193 336 0.010
receptor mediated endocytosis GO:0006898 51 0.010
interleukin 8 production GO:0032637 4 0.010
cellular response to gamma radiation GO:0071480 4 0.010
purine containing compound biosynthetic process GO:0072522 70 0.010
cellular response to nutrient levels GO:0031669 64 0.010
muscle cell differentiation GO:0042692 261 0.010
regulation of triglyceride biosynthetic process GO:0010866 10 0.010
monocarboxylic acid transport GO:0015718 44 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
leukocyte differentiation GO:0002521 342 0.010
positive regulation of organelle organization GO:0010638 128 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
cerebral cortex development GO:0021987 86 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
epithelium migration GO:0090132 63 0.010
defense response to other organism GO:0098542 197 0.010
negative regulation of mapk cascade GO:0043409 65 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010

Hmgcs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.157
inherited metabolic disorder DOID:655 0 0.157
disease of cellular proliferation DOID:14566 0 0.091
cancer DOID:162 0 0.057
lipid metabolism disorder DOID:3146 0 0.024
nervous system disease DOID:863 0 0.018
disease of anatomical entity DOID:7 0 0.018