|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.583
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.558
|
|
|
|
histone deubiquitination
|
GO:0016578 |
2 |
0.546
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.487
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.474
|
Fly |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.406
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.314
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.282
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.276
|
Worm |
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.269
|
Fly |
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.249
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
21 |
0.242
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.223
|
Worm |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.220
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.191
|
Worm |
|
|
membrane organization
|
GO:0061024 |
245 |
0.183
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.173
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.161
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.155
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.144
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.140
|
Worm Fly |
|
|
regionalization
|
GO:0003002 |
337 |
0.130
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.122
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.122
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.117
|
|
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
3 |
0.114
|
Fly |
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.098
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.093
|
|
|
|
protein deubiquitination
|
GO:0016579 |
19 |
0.092
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.092
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.092
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.090
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.088
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.084
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.083
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.077
|
|
|
|
endosome organization
|
GO:0007032 |
9 |
0.076
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.075
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.072
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.071
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.070
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.069
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.069
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.066
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.066
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.065
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.065
|
Worm |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.064
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.064
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.062
|
|
|
|
sensory perception of taste
|
GO:0050909 |
18 |
0.061
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.061
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.061
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.061
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.060
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.059
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.058
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.058
|
|
|
|
protein targeting to vacuole
|
GO:0006623 |
3 |
0.057
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.057
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.056
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.056
|
Worm |
|
|
lysosomal transport
|
GO:0007041 |
10 |
0.055
|
Worm |
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.055
|
|
|
|
regulation of toll signaling pathway
|
GO:0008592 |
1 |
0.055
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.055
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.055
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.054
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.054
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.053
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.052
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
1 |
0.051
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.050
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
20 |
0.050
|
Worm |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.049
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.049
|
|
|
|
establishment of protein localization to vacuole
|
GO:0072666 |
4 |
0.049
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.048
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.048
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.048
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.048
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.047
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.047
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.047
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.046
|
Fly |
|
|
gland development
|
GO:0048732 |
330 |
0.046
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.045
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.045
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.045
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.044
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.044
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.044
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.044
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.044
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.043
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.042
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.042
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.042
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.042
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.042
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.041
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.041
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.040
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.040
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.040
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.039
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.039
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.039
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.039
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.039
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.038
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.038
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.038
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.038
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.037
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.037
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.037
|
|
|
|
negative regulation of erbb signaling pathway
|
GO:1901185 |
7 |
0.037
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.037
|
Fly |
|
|
protein targeting
|
GO:0006605 |
143 |
0.037
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.036
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.036
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.035
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.035
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.034
|
|
|
|
cilium assembly
|
GO:0042384 |
81 |
0.034
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.034
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.034
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.034
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.033
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.033
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.033
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.033
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.033
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.033
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.033
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.032
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.032
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.032
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.032
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.032
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.032
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.032
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.032
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.032
|
Fly |
|
|
stem cell development
|
GO:0048864 |
219 |
0.031
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.031
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.031
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.031
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.031
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.031
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.031
|
Fly |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.030
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.030
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.030
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.030
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.030
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.030
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.029
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.029
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.029
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.029
|
Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.029
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.029
|
|
|
|
protein localization to vacuole
|
GO:0072665 |
4 |
0.029
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.028
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.028
|
Fly |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.028
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.028
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.028
|
Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.028
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.028
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.027
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.027
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.027
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.027
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.027
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.027
|
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.027
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.027
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.027
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.026
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.026
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.026
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.026
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.025
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.025
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.025
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.025
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.025
|
|
|
|
exosomal secretion
|
GO:1990182 |
1 |
0.025
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.025
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.025
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.025
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.025
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.025
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.025
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.024
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.024
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.024
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.024
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.024
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.024
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.024
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.024
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.024
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.023
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.023
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.023
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.023
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.023
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.023
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.023
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.022
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.022
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.022
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.022
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.022
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.022
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.022
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.022
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.022
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.022
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.022
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.022
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.022
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.021
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.021
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.021
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.021
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.021
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.021
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.021
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.021
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.021
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.021
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.021
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.020
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.020
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.020
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.020
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.020
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.020
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.020
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.020
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.020
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.020
|
|
|
|
negative regulation of fibroblast apoptotic process
|
GO:2000270 |
6 |
0.019
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.019
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.019
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.019
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.019
|
|
|
|
organelle fusion
|
GO:0048284 |
28 |
0.019
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.019
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.019
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.019
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.019
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.019
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.019
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.019
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.019
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.019
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.019
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.019
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.019
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.018
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.018
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
10 |
0.018
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.018
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.018
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.018
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.018
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.018
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.018
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.018
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.018
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.017
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.017
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.017
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.017
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.017
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.017
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.017
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.017
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.017
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.017
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.017
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.017
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.017
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.017
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.017
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.017
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.017
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.017
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.017
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.017
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.016
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.016
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.016
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.016
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.016
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.016
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.016
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.016
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.016
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.016
|
Fly |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.016
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.016
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.016
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.016
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.016
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.016
|
|
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.016
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.016
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.016
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.016
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.016
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.016
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.016
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.016
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.016
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.016
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.016
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.016
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.016
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.016
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.016
|
|
|
|
lipid phosphorylation
|
GO:0046834 |
25 |
0.015
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.015
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.015
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.015
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.015
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.015
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.015
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.015
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.015
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.015
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.015
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.015
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.015
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.015
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.015
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.015
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.015
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.015
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.015
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.015
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.015
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.014
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.014
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.014
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.014
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.014
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.014
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.014
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.014
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.014
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.014
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.014
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.014
|
Worm |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.014
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.014
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.014
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.014
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
7 |
0.014
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.014
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.014
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.014
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.014
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.014
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.014
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
34 |
0.014
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.014
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.014
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.014
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.014
|
Fly |
|
|
phosphatidylinositol phosphorylation
|
GO:0046854 |
23 |
0.014
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.014
|
Fly |
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.014
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.014
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.014
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.014
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.014
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.014
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.014
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.013
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.013
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.013
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.013
|
|
|
|
homophilic cell adhesion via plasma membrane adhesion molecules
|
GO:0007156 |
18 |
0.013
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.013
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.013
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.013
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.013
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.013
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.013
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.013
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.013
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
3 |
0.013
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.013
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.013
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.013
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.013
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.013
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.013
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.013
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.013
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.013
|
|
|
|
regulation of zinc ion transport
|
GO:0071579 |
2 |
0.013
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.013
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.013
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.013
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.013
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.013
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.013
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.013
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.013
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.013
|
|
|
|
positive regulation of macroautophagy
|
GO:0016239 |
3 |
0.012
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.012
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
27 |
0.012
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.012
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.012
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.012
|
|
|
|
cytokinesis
|
GO:0000910 |
17 |
0.012
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.012
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.012
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.012
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.012
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.012
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.012
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.012
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.012
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.012
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.012
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.012
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.012
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.012
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.012
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.012
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.012
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.012
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.012
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.012
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.012
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.012
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.012
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.012
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.012
|
|
|
|
learning
|
GO:0007612 |
98 |
0.012
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.012
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.012
|
Worm |
|
|
tube formation
|
GO:0035148 |
140 |
0.012
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.012
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.012
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.012
|
|
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
4 |
0.012
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.012
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.012
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.012
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.012
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.012
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.012
|
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.012
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.012
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.011
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.011
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.011
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.011
|
|
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.011
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.011
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.011
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.011
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.011
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.011
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.011
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.011
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.011
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.011
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.011
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.011
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.011
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.011
|
|
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
3 |
0.011
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.011
|
|
