Mus musculus

0 known processes

Fbxl8

F-box and leucine-rich repeat protein 8

(Aliases: FBL8)

Fbxl8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.077
cellular amine metabolic process GO:0044106 44 0.058
negative regulation of immune system process GO:0002683 209 0.053
regulation of cell activation GO:0050865 289 0.051
cellular ketone metabolic process GO:0042180 84 0.050
cation transmembrane transport GO:0098655 266 0.047
inorganic ion transmembrane transport GO:0098660 234 0.047
transmembrane transport GO:0055085 412 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
ion transmembrane transport GO:0034220 361 0.041
nucleotide metabolic process GO:0009117 332 0.039
cellular amino acid metabolic process GO:0006520 103 0.038
ribose phosphate metabolic process GO:0019693 291 0.037
inorganic cation transmembrane transport GO:0098662 207 0.035
protein catabolic process GO:0030163 221 0.035
regulation of lymphocyte activation GO:0051249 240 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
t cell activation GO:0042110 289 0.034
macromolecule catabolic process GO:0009057 281 0.034
cytokine production GO:0001816 319 0.033
cellular nitrogen compound catabolic process GO:0044270 280 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
cation transport GO:0006812 399 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
skin development GO:0043588 220 0.031
apoptotic signaling pathway GO:0097190 306 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
regulation of establishment of protein localization GO:0070201 181 0.030
leukocyte differentiation GO:0002521 342 0.030
epidermis development GO:0008544 187 0.029
regulation of defense response GO:0031347 233 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
oxidation reduction process GO:0055114 342 0.028
divalent inorganic cation transport GO:0072511 178 0.028
regulation of cytokine production GO:0001817 266 0.028
carbohydrate metabolic process GO:0005975 230 0.028
regulation of protein localization GO:0032880 231 0.028
immune effector process GO:0002252 321 0.028
cd4 positive alpha beta t cell activation GO:0035710 45 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.027
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
striated muscle tissue development GO:0014706 293 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
peptidyl amino acid modification GO:0018193 336 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
positive regulation of apoptotic process GO:0043065 217 0.024
regulation of hydrolase activity GO:0051336 246 0.024
regulation of protein transport GO:0051223 163 0.024
nitrogen compound transport GO:0071705 271 0.024
positive regulation of protein modification process GO:0031401 299 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
cellular homeostasis GO:0019725 240 0.024
ribonucleotide metabolic process GO:0009259 291 0.023
dna metabolic process GO:0006259 303 0.023
nucleoside metabolic process GO:0009116 246 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
regulation of nucleocytoplasmic transport GO:0046822 73 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
organelle assembly GO:0070925 177 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
intracellular protein transport GO:0006886 204 0.022
lymphocyte differentiation GO:0030098 242 0.022
regulation of secretion by cell GO:1903530 249 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
inflammatory response GO:0006954 244 0.022
cellular response to cytokine stimulus GO:0071345 189 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
gland development GO:0048732 330 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
compound eye development GO:0048749 1 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
aromatic compound catabolic process GO:0019439 286 0.021
regulation of feeding behavior GO:0060259 3 0.021
cation homeostasis GO:0055080 212 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
mapk cascade GO:0000165 281 0.020
adaptive immune response GO:0002250 155 0.020
anion transport GO:0006820 177 0.020
purine containing compound metabolic process GO:0072521 311 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
leukocyte mediated immunity GO:0002443 174 0.020
protein ubiquitination GO:0016567 171 0.020
ras protein signal transduction GO:0007265 77 0.020
cytoplasmic transport GO:0016482 234 0.019
regulation of organelle organization GO:0033043 289 0.019
peptide transport GO:0015833 133 0.019
regulation of intracellular transport GO:0032386 159 0.019
regulation of cell cycle GO:0051726 281 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
chromatin modification GO:0016568 187 0.019
glycoprotein metabolic process GO:0009100 116 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
lateral inhibition GO:0046331 1 0.019
cellular macromolecule catabolic process GO:0044265 206 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
interspecies interaction between organisms GO:0044419 83 0.018
divalent metal ion transport GO:0070838 172 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
response to acid chemical GO:0001101 111 0.018
cell adhesion GO:0007155 329 0.018
nucleotide catabolic process GO:0009166 217 0.018
negative regulation of cytokine production GO:0001818 84 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
protein localization to organelle GO:0033365 185 0.018
glycoprotein biosynthetic process GO:0009101 89 0.018
protein localization to nucleus GO:0034504 121 0.018
negative regulation of molecular function GO:0044092 258 0.018
endocytosis GO:0006897 168 0.018
protein import GO:0017038 101 0.017
response to organonitrogen compound GO:0010243 246 0.017
negative regulation of cell activation GO:0050866 111 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
cell type specific apoptotic process GO:0097285 268 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
ear development GO:0043583 200 0.017
regulation of cell projection organization GO:0031344 206 0.017
regulation of mapk cascade GO:0043408 248 0.017
nuclear transport GO:0051169 139 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
muscle cell differentiation GO:0042692 261 0.017
glycosylation GO:0070085 62 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.016
positive regulation of cytokine production GO:0001819 174 0.016
nucleoside catabolic process GO:0009164 206 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
fatty acid metabolic process GO:0006631 121 0.016
spermatogenesis GO:0007283 284 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
regulation of cellular response to stress GO:0080135 159 0.016
amide transport GO:0042886 138 0.016
rho protein signal transduction GO:0007266 32 0.016
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
alpha beta t cell activation GO:0046631 91 0.016
regulation of t cell activation GO:0050863 170 0.016
leukocyte proliferation GO:0070661 172 0.016
b cell activation GO:0042113 161 0.016
heterocycle catabolic process GO:0046700 280 0.015
camera type eye development GO:0043010 266 0.015
sensory perception GO:0007600 245 0.015
response to organic cyclic compound GO:0014070 198 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
organic anion transport GO:0015711 137 0.015
protein maturation GO:0051604 176 0.015
skeletal system development GO:0001501 356 0.015
cellular protein complex assembly GO:0043623 116 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
positive regulation of cell death GO:0010942 224 0.015
regulation of secretion GO:0051046 274 0.015
muscle tissue development GO:0060537 308 0.015
metal ion homeostasis GO:0055065 189 0.015
protein targeting GO:0006605 143 0.015
actin cytoskeleton organization GO:0030036 220 0.015
locomotory behavior GO:0007626 195 0.015
regulation of intracellular protein transport GO:0033157 82 0.014
cellular lipid metabolic process GO:0044255 323 0.014
protein import into nucleus GO:0006606 95 0.014
regulation of protein complex assembly GO:0043254 83 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
regulation of transferase activity GO:0051338 263 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
regulation of neuron differentiation GO:0045664 281 0.014
lipid transport GO:0006869 98 0.014
defense response to other organism GO:0098542 197 0.014
regulation of membrane potential GO:0042391 192 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
peptide secretion GO:0002790 114 0.014
endomembrane system organization GO:0010256 147 0.014
lymphocyte proliferation GO:0046651 164 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
defense response to bacterium GO:0042742 119 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
positive regulation of protein transport GO:0051222 93 0.014
calcium ion transport GO:0006816 159 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
single organism nuclear import GO:1902593 95 0.014
protein glycosylation GO:0006486 55 0.014
interleukin 6 production GO:0032635 58 0.014
positive regulation of defense response GO:0031349 124 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
nuclear division GO:0000280 158 0.014
purine containing compound catabolic process GO:0072523 213 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
microtubule based process GO:0007017 236 0.013
organelle fission GO:0048285 170 0.013
muscle system process GO:0003012 141 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
t cell differentiation GO:0030217 174 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
ossification GO:0001503 216 0.013
negative regulation of cell cycle GO:0045786 123 0.013
negative regulation of multi organism process GO:0043901 68 0.013
membrane organization GO:0061024 245 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
innate immune response GO:0045087 157 0.013
developmental maturation GO:0021700 193 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
defecation GO:0030421 1 0.013
atp metabolic process GO:0046034 75 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
anatomical structure homeostasis GO:0060249 145 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
striated muscle cell development GO:0055002 125 0.013
protein processing GO:0016485 163 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
striated muscle myosin thick filament assembly GO:0071688 1 0.013
sequestering of metal ion GO:0051238 19 0.013
positive regulation of cell activation GO:0050867 158 0.013
interferon beta biosynthetic process GO:0045350 4 0.013
oocyte axis specification GO:0007309 2 0.013
regulation of multi organism process GO:0043900 111 0.013
cellular chemical homeostasis GO:0055082 215 0.012
hindbrain development GO:0030902 128 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of interferon beta biosynthetic process GO:0045357 4 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
cellular ion homeostasis GO:0006873 165 0.012
protein secretion GO:0009306 111 0.012
blood vessel morphogenesis GO:0048514 285 0.012
maintenance of location GO:0051235 89 0.012
response to lipopolysaccharide GO:0032496 128 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
skeletal system morphogenesis GO:0048705 203 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
organophosphate catabolic process GO:0046434 232 0.012
nuclear import GO:0051170 95 0.012
cell activation involved in immune response GO:0002263 126 0.012
mitotic cell cycle GO:0000278 195 0.012
regulation of t cell differentiation GO:0045580 83 0.012
embryonic placenta development GO:0001892 98 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
vesicle localization GO:0051648 86 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
regulation of response to wounding GO:1903034 189 0.012
dephosphorylation GO:0016311 129 0.012
carbohydrate homeostasis GO:0033500 128 0.012
covalent chromatin modification GO:0016569 163 0.012
regulation of innate immune response GO:0045088 91 0.012
bone development GO:0060348 120 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
sequestering of calcium ion GO:0051208 18 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
muscle contraction GO:0006936 101 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
negative regulation of t cell activation GO:0050868 65 0.012
mesodermal cell migration GO:0008078 4 0.012
epithelial cell proliferation GO:0050673 174 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
calcium ion homeostasis GO:0055074 127 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
cellularization GO:0007349 1 0.011
chromatin organization GO:0006325 206 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
cartilage development GO:0051216 140 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
macromolecule glycosylation GO:0043413 55 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
defense response to virus GO:0051607 68 0.011
learning or memory GO:0007611 148 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of ion transport GO:0043269 215 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
germ cell development GO:0007281 185 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
alpha beta t cell differentiation GO:0046632 69 0.011
lytic vacuole organization GO:0080171 21 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
digestive tract development GO:0048565 190 0.011
respiratory system development GO:0060541 190 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
sensory system development GO:0048880 3 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
cardiac muscle tissue development GO:0048738 130 0.011
membrane tubulation GO:0097320 4 0.011
male gamete generation GO:0048232 285 0.011
muscle cell development GO:0055001 133 0.011
neuron apoptotic process GO:0051402 142 0.011
small molecule catabolic process GO:0044282 71 0.011
fat cell differentiation GO:0045444 160 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
protein oligomerization GO:0051259 67 0.011
regulation of protein catabolic process GO:0042176 108 0.010
oocyte construction GO:0007308 2 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
regulation of adaptive immune response GO:0002819 90 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
regulation of neuron projection development GO:0010975 169 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
protein polymerization GO:0051258 57 0.010
lipid localization GO:0010876 126 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
negative regulation of nervous system development GO:0051961 156 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
central nervous system neuron differentiation GO:0021953 162 0.010
mrna metabolic process GO:0016071 84 0.010
forebrain development GO:0030900 302 0.010
positive regulation of transferase activity GO:0051347 167 0.010
liver development GO:0001889 66 0.010

Fbxl8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
central nervous system disease DOID:331 0 0.017
immune system disease DOID:2914 0 0.016
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
disease of metabolism DOID:0014667 0 0.011
musculoskeletal system disease DOID:17 0 0.010