|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.339
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.314
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.205
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.201
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.193
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.190
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.184
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.174
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.164
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.151
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.146
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.143
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.142
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.138
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.137
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.130
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.127
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.122
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.117
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.112
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.112
|
Human Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.111
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.108
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.108
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.107
|
Mouse Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.104
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.102
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.101
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.096
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.095
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.094
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.093
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.092
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.090
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.089
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.088
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.087
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.086
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.085
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.085
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.083
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.081
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.081
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.081
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.080
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.080
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.079
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.077
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.075
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.074
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.073
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.072
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.071
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.071
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.071
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.070
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.070
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.069
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.069
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.069
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.067
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.065
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.065
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.064
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.064
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.063
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.063
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.062
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.062
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.062
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.061
|
Human Mouse Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.061
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.060
|
Human Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.059
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.059
|
Human Mouse Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.058
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.057
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.057
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.057
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.056
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.056
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.056
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.054
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.054
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.054
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.054
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.054
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.054
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.053
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.053
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.053
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.053
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.052
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.052
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.051
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.051
|
Mouse Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.051
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.051
|
Mouse Fly |
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.050
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.050
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.050
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.049
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.049
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.049
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.048
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.048
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.047
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.047
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.046
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.046
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.046
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.046
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.046
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.045
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.045
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.045
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.044
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.044
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.043
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.043
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.043
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.043
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.042
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.042
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.042
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.042
|
Fly |
|
|
sensory perception
|
GO:0007600 |
245 |
0.042
|
Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.042
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.041
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.041
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.041
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.041
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.040
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.040
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.040
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.040
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.039
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.039
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.039
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.038
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.038
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.038
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.038
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.038
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.037
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.037
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.037
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.037
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.037
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.037
|
Mouse |
|
|
microglia development
|
GO:0014005 |
2 |
0.037
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.037
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.036
|
Fly |
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.036
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.036
|
Worm |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.036
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.036
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.036
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.035
|
Mouse Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.035
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.035
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.035
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.035
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.035
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.034
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.034
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.034
|
Fly |
|
|
dna recombination
|
GO:0006310 |
92 |
0.034
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.034
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.034
|
Fly |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.034
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.033
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.033
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.033
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.033
|
Worm |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.033
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.033
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.033
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.032
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.032
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.032
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.032
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.032
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.031
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.031
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.031
|
Mouse Worm |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.031
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.031
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.031
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.031
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.031
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.031
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.031
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.031
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.030
|
Fly |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.030
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.030
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.030
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.030
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.030
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.030
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.030
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.030
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.030
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.030
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.030
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.030
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.030
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.030
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.029
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.029
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.029
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.029
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.029
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.029
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.029
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.029
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.029
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.029
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.029
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.028
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.028
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.028
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.028
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.028
|
Fly |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.028
|
Mouse Worm |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.028
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.028
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.028
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.028
|
Fly |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.028
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.028
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.028
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.028
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.028
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.027
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.027
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.027
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.027
|
Mouse |
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.027
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.027
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.027
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.027
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.027
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.027
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.027
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.027
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.027
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.026
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.026
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.026
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.026
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.026
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.026
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.026
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.026
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.026
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.026
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.026
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.026
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.026
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.026
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.026
|
Fly |
|
|
memory
|
GO:0007613 |
58 |
0.026
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.026
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.025
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.025
|
Mouse |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.025
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.025
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.025
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.025
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.025
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.025
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.025
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.024
|
Mouse |
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.024
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.024
|
Human |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.024
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.024
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.024
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.024
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.024
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.024
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.023
|
Mouse |
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.023
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.023
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.023
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.023
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.023
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.023
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.023
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.023
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.023
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.022
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.022
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.022
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.022
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.022
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.022
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.022
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.022
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.022
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.022
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.022
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.022
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.022
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.022
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.022
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.021
|
Human Mouse Fly |
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.021
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.021
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.021
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.021
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.021
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.021
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.021
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.021
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.021
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.021
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.021
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.021
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.020
|
Fly |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.020
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.020
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.020
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.020
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.020
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.020
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.020
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.020
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.020
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.020
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.020
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.020
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.020
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.020
|
Fly |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.019
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.019
|
|
|
|
sphingosine 1 phosphate signaling pathway
|
GO:0003376 |
3 |
0.019
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.019
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.019
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.019
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.019
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.019
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.019
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.019
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.019
|
|
|
|
establishment of endothelial blood brain barrier
|
GO:0014045 |
3 |
0.019
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.019
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.019
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.018
|
Fly |
|
|
cell maturation
|
GO:0048469 |
127 |
0.018
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.018
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.018
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.018
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.018
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.018
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.018
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.018
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.018
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.018
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.018
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.018
|
Mouse |
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.018
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.018
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.018
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.018
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.018
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.018
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.018
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.018
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.018
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.018
|
Mouse |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.018
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.017
|
Mouse |
|
|
positive regulation of interferon gamma secretion
|
GO:1902715 |
3 |
0.017
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.017
|
Fly |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.017
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.017
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.017
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.017
|
Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.017
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.017
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.017
|
Fly |
|
|
apical constriction
|
GO:0003383 |
4 |
0.017
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.017
|
Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.017
|
Mouse |
|
|
lipid localization
|
GO:0010876 |
126 |
0.017
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.017
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.017
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.017
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.017
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.017
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.017
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.017
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.017
|
Fly |
|
|
learning
|
GO:0007612 |
98 |
0.017
|
Mouse |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.017
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.017
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.017
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.017
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.017
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.017
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.017
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.016
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.016
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.016
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.016
|
Human |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.016
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.016
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.016
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.016
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.016
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.016
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.016
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.016
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.016
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.016
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.016
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.016
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.016
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.016
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.016
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.016
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.016
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.016
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.016
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.016
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.016
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.016
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.016
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.016
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.016
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.016
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.016
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.016
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.015
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.015
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.015
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.015
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.015
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.015
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.015
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.015
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.015
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.015
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.015
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.015
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.015
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.015
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.015
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.015
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
57 |
0.015
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.015
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.015
|
Mouse |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.015
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.015
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.015
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.015
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.015
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.015
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.015
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.015
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.015
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.015
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.015
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.015
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.015
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.014
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.014
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.014
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.014
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.014
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.014
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.014
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.014
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.014
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.014
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.014
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.014
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.014
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.014
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.014
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.014
|
Mouse |
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.014
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.014
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.014
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.014
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.014
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.014
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.014
|
|
|
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.014
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.014
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.014
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.014
|
|
