Mus musculus

0 known processes

Plekha2

pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2

(Aliases: 6430512N22Rik,AI851530,W91773,TAPP2,AU041791)

Plekha2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.318
organic cyclic compound catabolic process GO:1901361 295 0.289
purine ribonucleoside metabolic process GO:0046128 241 0.176
glycosyl compound catabolic process GO:1901658 206 0.164
regulation of hydrolase activity GO:0051336 246 0.159
nucleoside catabolic process GO:0009164 206 0.138
purine nucleotide catabolic process GO:0006195 211 0.137
aromatic compound catabolic process GO:0019439 286 0.136
nucleoside phosphate metabolic process GO:0006753 338 0.131
nucleobase containing small molecule metabolic process GO:0055086 352 0.127
glycosyl compound metabolic process GO:1901657 246 0.125
actin filament organization GO:0007015 113 0.122
nucleotide metabolic process GO:0009117 332 0.119
heterocycle catabolic process GO:0046700 280 0.119
ras protein signal transduction GO:0007265 77 0.117
regulation of organelle organization GO:0033043 289 0.117
cellular nitrogen compound catabolic process GO:0044270 280 0.115
purine nucleoside triphosphate catabolic process GO:0009146 203 0.112
mapk cascade GO:0000165 281 0.112
purine nucleotide metabolic process GO:0006163 302 0.108
ribonucleotide catabolic process GO:0009261 208 0.106
negative regulation of protein phosphorylation GO:0001933 126 0.106
ribonucleoside triphosphate metabolic process GO:0009199 220 0.106
ribonucleoside metabolic process GO:0009119 245 0.104
negative regulation of molecular function GO:0044092 258 0.101
cellular amine metabolic process GO:0044106 44 0.099
carbohydrate derivative catabolic process GO:1901136 231 0.099
negative regulation of protein metabolic process GO:0051248 282 0.099
ribonucleoside triphosphate catabolic process GO:0009203 199 0.099
purine ribonucleotide metabolic process GO:0009150 290 0.097
regulation of mapk cascade GO:0043408 248 0.097
nucleoside metabolic process GO:0009116 246 0.094
ribonucleotide metabolic process GO:0009259 291 0.092
organonitrogen compound catabolic process GO:1901565 264 0.091
negative regulation of phosphorus metabolic process GO:0010563 184 0.091
regulation of cellular amine metabolic process GO:0033238 20 0.091
small gtpase mediated signal transduction GO:0007264 97 0.089
purine nucleoside triphosphate metabolic process GO:0009144 226 0.088
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.086
macromolecule catabolic process GO:0009057 281 0.084
nucleoside triphosphate catabolic process GO:0009143 205 0.082
amine metabolic process GO:0009308 45 0.082
ribonucleoside catabolic process GO:0042454 206 0.079
regulation of cellular amino acid metabolic process GO:0006521 5 0.078
lymphocyte differentiation GO:0030098 242 0.078
transmembrane transport GO:0055085 412 0.077
ribose phosphate metabolic process GO:0019693 291 0.077
purine containing compound metabolic process GO:0072521 311 0.077
purine ribonucleotide catabolic process GO:0009154 208 0.075
peptidyl amino acid modification GO:0018193 336 0.074
apoptotic signaling pathway GO:0097190 306 0.073
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.073
regulation of actin filament length GO:0030832 45 0.072
organophosphate catabolic process GO:0046434 232 0.072
gtp catabolic process GO:0006184 143 0.071
cell adhesion GO:0007155 329 0.071
Human
regulation of actin filament polymerization GO:0030833 38 0.070
nucleoside phosphate catabolic process GO:1901292 222 0.069
regulation of actin filament based process GO:0032970 99 0.069
negative regulation of phosphate metabolic process GO:0045936 184 0.068
purine nucleoside metabolic process GO:0042278 241 0.068
muscle cell differentiation GO:0042692 261 0.066
regulation of ras gtpase activity GO:0032318 88 0.066
negative regulation of phosphorylation GO:0042326 166 0.065
regulation of cellular component biogenesis GO:0044087 181 0.065
nucleoside triphosphate metabolic process GO:0009141 230 0.065
establishment of organelle localization GO:0051656 122 0.064
purine containing compound catabolic process GO:0072523 213 0.064
nucleotide catabolic process GO:0009166 217 0.064
negative regulation of immune system process GO:0002683 209 0.063
actin filament polymerization GO:0030041 44 0.063
immune effector process GO:0002252 321 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.060
synaptic transmission GO:0007268 329 0.059
cellular amino acid metabolic process GO:0006520 103 0.058
regulation of membrane potential GO:0042391 192 0.058
cellular protein complex assembly GO:0043623 116 0.056
guanosine containing compound catabolic process GO:1901069 144 0.056
regulation of innate immune response GO:0045088 91 0.056
regulation of cytoskeleton organization GO:0051493 122 0.055
regulation of purine nucleotide metabolic process GO:1900542 169 0.054
regulation of actin cytoskeleton organization GO:0032956 84 0.053
cellular lipid metabolic process GO:0044255 323 0.053
activation of immune response GO:0002253 138 0.053
regulation of kinase activity GO:0043549 249 0.053
cytokine production GO:0001816 319 0.052
positive regulation of protein modification process GO:0031401 299 0.051
cellular response to lipopolysaccharide GO:0071222 77 0.051
regulation of cellular catabolic process GO:0031329 242 0.051
cellular component assembly involved in morphogenesis GO:0010927 139 0.050
cellular macromolecule catabolic process GO:0044265 206 0.050
myosin filament organization GO:0031033 3 0.049
carbohydrate metabolic process GO:0005975 230 0.049
b cell activation GO:0042113 161 0.049
negative regulation of protein modification process GO:0031400 163 0.048
protein catabolic process GO:0030163 221 0.048
regulation of cell motility GO:2000145 236 0.047
endocytosis GO:0006897 168 0.046
regulation of transferase activity GO:0051338 263 0.046
positive regulation of cellular catabolic process GO:0031331 148 0.046
membrane organization GO:0061024 245 0.046
interspecies interaction between organisms GO:0044419 83 0.045
organelle localization GO:0051640 179 0.045
myosin filament assembly GO:0031034 2 0.045
positive regulation of gtp catabolic process GO:0033126 85 0.045
response to peptide GO:1901652 136 0.045
cation transport GO:0006812 399 0.044
intrinsic apoptotic signaling pathway GO:0097193 132 0.044
purine nucleoside catabolic process GO:0006152 205 0.044
muscle cell development GO:0055001 133 0.044
regulation of cell activation GO:0050865 289 0.044
negative regulation of cellular amine metabolic process GO:0033239 1 0.044
regulation of protein complex assembly GO:0043254 83 0.044
regulation of defense response GO:0031347 233 0.044
regulation of nucleoside metabolic process GO:0009118 130 0.042
cellular response to growth factor stimulus GO:0071363 197 0.042
regulation of gtp catabolic process GO:0033124 113 0.042
regionalization GO:0003002 337 0.040
epidermis development GO:0008544 187 0.039
carbohydrate derivative biosynthetic process GO:1901137 183 0.039
positive regulation of hydrolase activity GO:0051345 148 0.039
negative regulation of transferase activity GO:0051348 85 0.039
cytoplasmic transport GO:0016482 234 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.038
positive regulation of gtpase activity GO:0043547 85 0.038
maintenance of location GO:0051235 89 0.038
epithelial tube morphogenesis GO:0060562 303 0.037
leukocyte migration GO:0050900 124 0.037
cation transmembrane transport GO:0098655 266 0.037
organelle fission GO:0048285 170 0.037
leukocyte differentiation GO:0002521 342 0.037
regulation of leukocyte differentiation GO:1902105 159 0.037
regulation of endopeptidase activity GO:0052548 89 0.037
cellular ketone metabolic process GO:0042180 84 0.037
circulatory system process GO:0003013 197 0.037
striated muscle myosin thick filament assembly GO:0071688 1 0.036
defense response to other organism GO:0098542 197 0.036
actin filament bundle assembly GO:0051017 40 0.036
cellular response to biotic stimulus GO:0071216 92 0.036
regulation of actin polymerization or depolymerization GO:0008064 45 0.036
actomyosin structure organization GO:0031032 56 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
regulation of apoptotic signaling pathway GO:2001233 197 0.036
germ cell development GO:0007281 185 0.036
purine ribonucleoside catabolic process GO:0046130 205 0.035
positive regulation of programmed cell death GO:0043068 218 0.035
regulation of t cell activation GO:0050863 170 0.035
microtubule based process GO:0007017 236 0.035
peptidyl tyrosine modification GO:0018212 145 0.035
myeloid cell differentiation GO:0030099 233 0.035
g protein coupled receptor signaling pathway GO:0007186 243 0.034
regulation of protein kinase activity GO:0045859 232 0.034
rho protein signal transduction GO:0007266 32 0.034
inorganic ion transmembrane transport GO:0098660 234 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.033
actin polymerization or depolymerization GO:0008154 54 0.033
response to molecule of bacterial origin GO:0002237 143 0.033
protein maturation GO:0051604 176 0.033
cell activation involved in immune response GO:0002263 126 0.033
cellular response to organonitrogen compound GO:0071417 145 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.032
skin development GO:0043588 220 0.032
positive regulation of nucleotide catabolic process GO:0030813 88 0.032
response to lipopolysaccharide GO:0032496 128 0.032
regulation of actin nucleation GO:0051125 4 0.032
positive regulation of nucleoside metabolic process GO:0045979 91 0.032
microtubule cytoskeleton organization GO:0000226 157 0.032
inorganic cation transmembrane transport GO:0098662 207 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
regulation of peptidase activity GO:0052547 96 0.031
regulation of cytokine production GO:0001817 266 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.031
regulation of cell cycle GO:0051726 281 0.031
chromatin modification GO:0016568 187 0.031
regulation of nucleotide catabolic process GO:0030811 122 0.030
positive regulation of apoptotic signaling pathway GO:2001235 95 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
positive regulation of ras gtpase activity GO:0032320 65 0.030
divalent inorganic cation transport GO:0072511 178 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
gtp metabolic process GO:0046039 144 0.030
leukocyte proliferation GO:0070661 172 0.030
mitochondrion organization GO:0007005 134 0.030
chromatin organization GO:0006325 206 0.030
regulation of lymphocyte activation GO:0051249 240 0.030
immune response regulating signaling pathway GO:0002764 125 0.029
nuclear division GO:0000280 158 0.029
regulation of cell migration GO:0030334 219 0.029
positive regulation of organelle organization GO:0010638 128 0.029
axonogenesis GO:0007409 274 0.029
regulation of proteolysis GO:0030162 164 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of secretion GO:0051046 274 0.029
striated muscle cell development GO:0055002 125 0.029
protein localization to organelle GO:0033365 185 0.029
response to organonitrogen compound GO:0010243 246 0.028
blood vessel morphogenesis GO:0048514 285 0.028
cellular homeostasis GO:0019725 240 0.028
immune response activating signal transduction GO:0002757 116 0.028
negative regulation of kinase activity GO:0033673 81 0.028
regulation of hormone levels GO:0010817 211 0.028
Mouse
cellular response to hormone stimulus GO:0032870 150 0.028
organelle assembly GO:0070925 177 0.028
response to growth factor GO:0070848 198 0.028
leukocyte activation involved in immune response GO:0002366 126 0.028
positive regulation of mapk cascade GO:0043410 170 0.028
cellular response to molecule of bacterial origin GO:0071219 83 0.028
regulation of multi organism process GO:0043900 111 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
positive regulation of cell death GO:0010942 224 0.027
protein polymerization GO:0051258 57 0.027
leukocyte mediated immunity GO:0002443 174 0.027
nucleoside monophosphate metabolic process GO:0009123 85 0.027
digestive system development GO:0055123 200 0.027
regulation of protein catabolic process GO:0042176 108 0.027
endomembrane system organization GO:0010256 147 0.027
sequestering of metal ion GO:0051238 19 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
negative regulation of cell proliferation GO:0008285 296 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
t cell activation GO:0042110 289 0.026
positive regulation of cytokine production GO:0001819 174 0.026
exocytosis GO:0006887 121 0.026
t cell differentiation GO:0030217 174 0.026
negative regulation of nervous system development GO:0051961 156 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
positive regulation of nervous system development GO:0051962 221 0.025
response to organic cyclic compound GO:0014070 198 0.025
regulation of secretion by cell GO:1903530 249 0.025
proteasomal protein catabolic process GO:0010498 98 0.025
muscle contraction GO:0006936 101 0.025
regulation of cell adhesion GO:0030155 154 0.025
Human
gland development GO:0048732 330 0.025
calcium ion transport GO:0006816 159 0.025
tube formation GO:0035148 140 0.025
innate immune response GO:0045087 157 0.025
dephosphorylation GO:0016311 129 0.025
digestive tract development GO:0048565 190 0.025
forebrain development GO:0030900 302 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
positive regulation of innate immune response GO:0045089 80 0.025
sensory organ morphogenesis GO:0090596 242 0.025
b cell proliferation GO:0042100 53 0.024
divalent metal ion transport GO:0070838 172 0.024
regulation of neuron differentiation GO:0045664 281 0.024
activation of innate immune response GO:0002218 56 0.024
histone modification GO:0016570 159 0.024
cellular ion homeostasis GO:0006873 165 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
epithelial cell development GO:0002064 159 0.024
lymphocyte proliferation GO:0046651 164 0.024
regulation of intracellular transport GO:0032386 159 0.024
negative regulation of organelle organization GO:0010639 90 0.024
covalent chromatin modification GO:0016569 163 0.024
regulation of system process GO:0044057 200 0.024
inflammatory response GO:0006954 244 0.024
erk1 and erk2 cascade GO:0070371 77 0.024
compound eye development GO:0048749 1 0.023
alpha beta t cell activation GO:0046631 91 0.023
response to peptide hormone GO:0043434 127 0.023
intracellular protein transport GO:0006886 204 0.023
regulation of rho gtpase activity GO:0032319 58 0.023
sequestering of calcium ion GO:0051208 18 0.023
rhythmic process GO:0048511 174 0.023
Mouse
positive regulation of cell activation GO:0050867 158 0.023
plasma membrane organization GO:0007009 90 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
cation homeostasis GO:0055080 212 0.022
nitrogen compound transport GO:0071705 271 0.022
protein processing GO:0016485 163 0.022
glycoprotein metabolic process GO:0009100 116 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
regulation of cell projection organization GO:0031344 206 0.022
establishment of vesicle localization GO:0051650 81 0.022
mitotic cell cycle GO:0000278 195 0.022
cellular protein catabolic process GO:0044257 155 0.022
phospholipid metabolic process GO:0006644 87 0.022
cellular response to lipid GO:0071396 145 0.022
vesicle localization GO:0051648 86 0.021
mitotic cell cycle process GO:1903047 159 0.021
oxidation reduction process GO:0055114 342 0.021
protein localization to membrane GO:0072657 108 0.021
positive regulation of cell development GO:0010720 237 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
calcium ion transmembrane transport GO:0070588 85 0.021
oocyte anterior posterior axis specification GO:0007314 2 0.021
ion transmembrane transport GO:0034220 361 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
lipid homeostasis GO:0055088 63 0.021
muscle tissue development GO:0060537 308 0.021
antigen receptor mediated signaling pathway GO:0050851 64 0.020
positive regulation of nucleotide metabolic process GO:0045981 114 0.020
response to inorganic substance GO:0010035 96 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
homeostasis of number of cells GO:0048872 210 0.020
cell division GO:0051301 120 0.020
pattern recognition receptor signaling pathway GO:0002221 47 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.020
positive regulation of cellular component biogenesis GO:0044089 94 0.020
cellular response to abiotic stimulus GO:0071214 56 0.020
chemotaxis GO:0006935 247 0.020
stem cell differentiation GO:0048863 268 0.020
protein localization to nucleus GO:0034504 121 0.020
glycoprotein biosynthetic process GO:0009101 89 0.020
calcium ion homeostasis GO:0055074 127 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
carbohydrate homeostasis GO:0033500 128 0.019
regulation of anatomical structure size GO:0090066 178 0.019
regulation of t cell differentiation GO:0045580 83 0.019
negative regulation of protein maturation GO:1903318 79 0.019
regulation of intracellular protein transport GO:0033157 82 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
angiogenesis GO:0001525 201 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
negative regulation of endopeptidase activity GO:0010951 44 0.018
negative regulation of cell activation GO:0050866 111 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
myotube differentiation GO:0014902 105 0.018
cellular response to peptide GO:1901653 92 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of protein processing GO:0070613 96 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
protein ubiquitination GO:0016567 171 0.018
protein targeting GO:0006605 143 0.018
regulation of response to biotic stimulus GO:0002831 38 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
amide transport GO:0042886 138 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
cellular chemical homeostasis GO:0055082 215 0.018
adaptive immune response GO:0002250 155 0.018
atp catabolic process GO:0006200 55 0.018
dna metabolic process GO:0006259 303 0.018
maternal determination of anterior posterior axis embryo GO:0008358 2 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
stem cell development GO:0048864 219 0.017
regulation of protein maturation GO:1903317 96 0.017
alcohol metabolic process GO:0006066 116 0.017
purine nucleoside monophosphate catabolic process GO:0009128 58 0.017
myeloid cell homeostasis GO:0002262 114 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
myeloid leukocyte activation GO:0002274 83 0.017
keratinocyte differentiation GO:0030216 48 0.017
positive regulation of cytoskeleton organization GO:0051495 49 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
atp metabolic process GO:0046034 75 0.017
regulation of cell cycle process GO:0010564 160 0.017
regulation of muscle contraction GO:0006937 49 0.017
positive regulation of proteolysis GO:0045862 85 0.017
response to oxidative stress GO:0006979 123 0.017
anion transport GO:0006820 177 0.017
negative regulation of growth GO:0045926 99 0.017
locomotory behavior GO:0007626 195 0.017
spermatogenesis GO:0007283 284 0.017
Mouse
negative regulation of cytokine production GO:0001818 84 0.017
cell substrate adhesion GO:0031589 130 0.016
Human
developmental maturation GO:0021700 193 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
negative regulation of t cell activation GO:0050868 65 0.016
cell type specific apoptotic process GO:0097285 268 0.016
regulation of transmembrane transport GO:0034762 128 0.016
telencephalon development GO:0021537 186 0.016
epithelial tube formation GO:0072175 130 0.016
interleukin 8 production GO:0032637 4 0.016
epithelial cell proliferation GO:0050673 174 0.016
positive regulation of interferon alpha production GO:0032727 4 0.016
negative regulation of cytoskeleton organization GO:0051494 36 0.016
b cell differentiation GO:0030183 78 0.016
regulation of nuclear division GO:0051783 56 0.016
regulation of cellular component size GO:0032535 121 0.016
single organism cell adhesion GO:0098602 156 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
positive regulation of rho gtpase activity GO:0032321 41 0.016
response to radiation GO:0009314 165 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
negative regulation of mapk cascade GO:0043409 65 0.016
wound healing GO:0042060 157 0.016
protein oligomerization GO:0051259 67 0.016
generation of precursor metabolites and energy GO:0006091 103 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
lateral inhibition GO:0046331 1 0.016
positive regulation of protein complex assembly GO:0031334 45 0.016
epithelial cell morphogenesis GO:0003382 41 0.016
regulation of b cell activation GO:0050864 81 0.015
negative regulation of cell migration GO:0030336 59 0.015
cell fate commitment GO:0045165 210 0.015
positive regulation of peptidase activity GO:0010952 49 0.015
glucose homeostasis GO:0042593 128 0.015
metal ion homeostasis GO:0055065 189 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
protein autophosphorylation GO:0046777 61 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
alpha beta t cell differentiation GO:0046632 69 0.015
respiratory system development GO:0060541 190 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
defecation GO:0030421 1 0.015
response to oxygen levels GO:0070482 62 0.015
cytokinetic process GO:0032506 2 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
lipid localization GO:0010876 126 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
negative regulation of homeostatic process GO:0032845 71 0.015
microtubule based movement GO:0007018 84 0.015
negative regulation of synaptic vesicle transport GO:1902804 3 0.015
striated muscle tissue development GO:0014706 293 0.015
operant conditioning GO:0035106 2 0.015
response to insulin GO:0032868 100 0.015
neural tube formation GO:0001841 108 0.014
rhodopsin mediated signaling pathway GO:0016056 4 0.014
negative regulation of cell development GO:0010721 169 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
peptidyl serine modification GO:0018209 83 0.014
wnt signaling pathway GO:0016055 188 0.014
cd4 positive alpha beta t cell activation GO:0035710 45 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
alpha amino acid metabolic process GO:1901605 59 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
hormone secretion GO:0046879 128 0.014
regulation of neuron death GO:1901214 134 0.014
establishment or maintenance of cell polarity GO:0007163 86 0.014
negative regulation of multi organism process GO:0043901 68 0.014
learning or memory GO:0007611 148 0.014
camera type eye development GO:0043010 266 0.014
regulation of homeostatic process GO:0032844 182 0.014
response to light stimulus GO:0009416 135 0.014
apical constriction GO:0003383 4 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of lamellipodium assembly GO:0010591 3 0.014
positive regulation of actin filament polymerization GO:0030838 26 0.014
positive regulation of transferase activity GO:0051347 167 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
protein localization to plasma membrane GO:0072659 57 0.014
macromolecule glycosylation GO:0043413 55 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
calcium ion transport into cytosol GO:0060402 48 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
rap protein signal transduction GO:0032486 3 0.014
synapse organization GO:0050808 125 0.014
oocyte axis specification GO:0007309 2 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
cellular response to radiation GO:0071478 28 0.014
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.013
regulation of neuron projection development GO:0010975 169 0.013
regulation of ion transport GO:0043269 215 0.013
oocyte construction GO:0007308 2 0.013
t cell proliferation GO:0042098 120 0.013
cardiac muscle cell differentiation GO:0055007 69 0.013
regulation of chromosome organization GO:0033044 83 0.013
regulation of calcium ion transport GO:0051924 69 0.013
regulation of interferon beta biosynthetic process GO:0045357 4 0.013
regulation of muscle system process GO:0090257 80 0.013
regulation of protein transport GO:0051223 163 0.013
actin filament based movement GO:0030048 23 0.013
regulation of cell division GO:0051302 76 0.013
regulation of binding GO:0051098 111 0.013
neural tube closure GO:0001843 90 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
regulation of endocytosis GO:0030100 69 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
positive regulation of cell adhesion GO:0045785 80 0.013
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
mitochondrion distribution GO:0048311 4 0.013
glial cell apoptotic process GO:0034349 3 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.013
cognition GO:0050890 149 0.013
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.013
ossification GO:0001503 216 0.013
g protein coupled receptor internalization GO:0002031 3 0.013
rac protein signal transduction GO:0016601 13 0.013
peptide transport GO:0015833 133 0.013

Plekha2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
immune system disease DOID:2914 0 0.021
sensory system disease DOID:0050155 0 0.015
organ system cancer DOID:0050686 0 0.013