Mus musculus

0 known processes

Cobra1

cofactor of BRCA1

(Aliases: A730008L03Rik,Nelf-b,AB041607,AI663983)

Cobra1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of synapse assembly GO:0051964 3 0.151
membrane organization GO:0061024 245 0.145
positive regulation of apoptotic process GO:0043065 217 0.125
ras protein signal transduction GO:0007265 77 0.114
cellular ketone metabolic process GO:0042180 84 0.109
regulation of cellular ketone metabolic process GO:0010565 66 0.102
aromatic compound catabolic process GO:0019439 286 0.093
positive regulation of protein modification process GO:0031401 299 0.089
cellular response to dna damage stimulus GO:0006974 207 0.088
nucleotide metabolic process GO:0009117 332 0.085
positive regulation of apoptotic signaling pathway GO:2001235 95 0.078
nucleobase containing small molecule metabolic process GO:0055086 352 0.076
histone modification GO:0016570 159 0.074
cellular amine metabolic process GO:0044106 44 0.072
protein modification by small protein conjugation or removal GO:0070647 207 0.069
skin development GO:0043588 220 0.064
regulation of protein kinase activity GO:0045859 232 0.064
protein localization to organelle GO:0033365 185 0.064
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.059
covalent chromatin modification GO:0016569 163 0.059
endocytosis GO:0006897 168 0.059
gtp metabolic process GO:0046039 144 0.058
ribonucleotide metabolic process GO:0009259 291 0.058
maintenance of location GO:0051235 89 0.056
regulation of cell cycle GO:0051726 281 0.055
regulation of neuron differentiation GO:0045664 281 0.055
positive regulation of cell death GO:0010942 224 0.055
regulation of cell projection organization GO:0031344 206 0.050
positive regulation of programmed cell death GO:0043068 218 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
negative regulation of protein metabolic process GO:0051248 282 0.048
negative regulation of cellular component organization GO:0051129 194 0.047
macromolecule methylation GO:0043414 120 0.047
apoptotic signaling pathway GO:0097190 306 0.047
protein ubiquitination GO:0016567 171 0.046
ribose phosphate metabolic process GO:0019693 291 0.046
response to radiation GO:0009314 165 0.046
regulation of proteolysis GO:0030162 164 0.046
urogenital system development GO:0001655 261 0.045
heterocycle catabolic process GO:0046700 280 0.045
retrograde transport endosome to golgi GO:0042147 2 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.044
chromatin modification GO:0016568 187 0.044
methylation GO:0032259 134 0.042
response to light stimulus GO:0009416 135 0.042
nucleotide catabolic process GO:0009166 217 0.041
small gtpase mediated signal transduction GO:0007264 97 0.041
organic cyclic compound catabolic process GO:1901361 295 0.040
asymmetric neuroblast division GO:0055059 1 0.040
dna metabolic process GO:0006259 303 0.039
organophosphate catabolic process GO:0046434 232 0.039
cytokine production GO:0001816 319 0.038
tissue homeostasis GO:0001894 115 0.038
purine containing compound metabolic process GO:0072521 311 0.037
multicellular organismal homeostasis GO:0048871 164 0.037
chemotaxis GO:0006935 247 0.037
positive regulation of nervous system development GO:0051962 221 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
positive regulation of protein phosphorylation GO:0001934 242 0.035
wnt signaling pathway GO:0016055 188 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
endomembrane system organization GO:0010256 147 0.035
nitrogen compound transport GO:0071705 271 0.035
regulation of protein serine threonine kinase activity GO:0071900 157 0.035
regulation of establishment of protein localization GO:0070201 181 0.034
anatomical structure homeostasis GO:0060249 145 0.034
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.034
nuclear division GO:0000280 158 0.034
regulation of hydrolase activity GO:0051336 246 0.033
purine containing compound catabolic process GO:0072523 213 0.033
regulation of homeostatic process GO:0032844 182 0.033
positive regulation of synaptic plasticity GO:0031915 4 0.033
purine nucleotide metabolic process GO:0006163 302 0.032
cellular response to salt stress GO:0071472 1 0.032
positive regulation of cell development GO:0010720 237 0.032
regulation of nucleoside metabolic process GO:0009118 130 0.032
muscle cell differentiation GO:0042692 261 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
negative regulation of nervous system development GO:0051961 156 0.030
developmental maturation GO:0021700 193 0.030
cellular response to lipid GO:0071396 145 0.030
regulation of purine nucleotide catabolic process GO:0033121 122 0.030
protein targeting GO:0006605 143 0.030
positive regulation of neuron projection development GO:0010976 79 0.030
protein maturation GO:0051604 176 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
regulation of kinase activity GO:0043549 249 0.029
negative regulation of cell proliferation GO:0008285 296 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
rhythmic process GO:0048511 174 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.029
regulation of transferase activity GO:0051338 263 0.028
intracellular protein transport GO:0006886 204 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
negative regulation of phosphorylation GO:0042326 166 0.028
regulation of cell cycle process GO:0010564 160 0.028
regulation of mitotic cell cycle phase transition GO:1901990 73 0.028
asymmetric stem cell division GO:0098722 3 0.028
regulation of hormone secretion GO:0046883 88 0.028
kidney development GO:0001822 213 0.027
amine metabolic process GO:0009308 45 0.027
positive regulation of proteolysis GO:0045862 85 0.027
regulation of vesicle mediated transport GO:0060627 139 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
macromolecule catabolic process GO:0009057 281 0.026
guanosine containing compound catabolic process GO:1901069 144 0.026
mitotic cell cycle process GO:1903047 159 0.025
regulation of synaptic plasticity GO:0048167 87 0.025
regulation of binding GO:0051098 111 0.025
protein secretion GO:0009306 111 0.025
cellular homeostasis GO:0019725 240 0.025
dendrite development GO:0016358 115 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
lipid localization GO:0010876 126 0.025
negative regulation of molecular function GO:0044092 258 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.024
protein localization to nucleus GO:0034504 121 0.024
regulation of intracellular transport GO:0032386 159 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
mitochondrion organization GO:0007005 134 0.024
mitotic cell cycle GO:0000278 195 0.024
homeostasis of number of cells GO:0048872 210 0.024
axonogenesis GO:0007409 274 0.024
sensory perception GO:0007600 245 0.024
regulation of neuron projection development GO:0010975 169 0.024
regulation of anatomical structure size GO:0090066 178 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
male gamete generation GO:0048232 285 0.023
regulation of protein localization GO:0032880 231 0.023
cytoplasmic transport GO:0016482 234 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
metal ion homeostasis GO:0055065 189 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
positive regulation of kinase activity GO:0033674 155 0.022
gtp catabolic process GO:0006184 143 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
spermatid differentiation GO:0048515 115 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
regulation of map kinase activity GO:0043405 120 0.022
ubiquitin dependent protein catabolic process GO:0006511 129 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
regulation of mapk cascade GO:0043408 248 0.021
actin cytoskeleton organization GO:0030036 220 0.021
regulation of secretion GO:0051046 274 0.021
organelle localization GO:0051640 179 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
mapk cascade GO:0000165 281 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
positive regulation of mapk cascade GO:0043410 170 0.020
regulation of hormone levels GO:0010817 211 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
positive regulation of transferase activity GO:0051347 167 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.020
regulation of ras protein signal transduction GO:0046578 114 0.020
spermatogenesis GO:0007283 284 0.020
nucleoside metabolic process GO:0009116 246 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
protein polyubiquitination GO:0000209 33 0.020
myeloid cell differentiation GO:0030099 233 0.020
synapse organization GO:0050808 125 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
synapse assembly GO:0007416 56 0.019
regulation of cell activation GO:0050865 289 0.019
telencephalon development GO:0021537 186 0.019
negative regulation of cell development GO:0010721 169 0.019
negative regulation of growth GO:0045926 99 0.019
epidermis development GO:0008544 187 0.019
regulation of endocytosis GO:0030100 69 0.019
blood circulation GO:0008015 195 0.019
peptidyl amino acid modification GO:0018193 336 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
cell growth GO:0016049 130 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
response to organic cyclic compound GO:0014070 198 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
divalent inorganic cation transport GO:0072511 178 0.019
protein processing GO:0016485 163 0.019
cell fate commitment GO:0045165 210 0.019
positive regulation of neuron differentiation GO:0045666 141 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of cell size GO:0008361 72 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
synaptic transmission GO:0007268 329 0.018
chromatin organization GO:0006325 206 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
locomotory behavior GO:0007626 195 0.018
regulation of secretion by cell GO:1903530 249 0.018
germ cell development GO:0007281 185 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
negative regulation of protein modification process GO:0031400 163 0.018
negative regulation of wnt signaling pathway GO:0030178 73 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
activation of mapkkk activity GO:0000185 1 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
negative regulation of cell cycle GO:0045786 123 0.017
regulation of organelle organization GO:0033043 289 0.017
inflammatory response GO:0006954 244 0.017
positive regulation of gtpase activity GO:0043547 85 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
negative regulation of organelle organization GO:0010639 90 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
leukocyte differentiation GO:0002521 342 0.017
lateral inhibition GO:0046331 1 0.017
negative regulation of transferase activity GO:0051348 85 0.017
regulation of system process GO:0044057 200 0.017
response to organonitrogen compound GO:0010243 246 0.017
intracellular receptor signaling pathway GO:0030522 74 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of cytokine production GO:0001817 266 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
negative regulation of cell size GO:0045792 3 0.016
regulation of vacuole organization GO:0044088 4 0.016
rho protein signal transduction GO:0007266 32 0.016
protein catabolic process GO:0030163 221 0.016
interleukin 8 production GO:0032637 4 0.016
cellular hyperosmotic salinity response GO:0071475 0 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
cellular protein catabolic process GO:0044257 155 0.016
regulation of cell motility GO:2000145 236 0.015
response to lipopolysaccharide GO:0032496 128 0.015
dna repair GO:0006281 107 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
maintenance of protein location in cell GO:0032507 20 0.015
blood vessel morphogenesis GO:0048514 285 0.015
cognition GO:0050890 149 0.015
tube formation GO:0035148 140 0.015
striated muscle cell development GO:0055002 125 0.015
regulation of transposition GO:0010528 2 0.015
microtubule based process GO:0007017 236 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.014
amide transport GO:0042886 138 0.014
heart contraction GO:0060047 93 0.014
regulation of peptide transport GO:0090087 91 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of ossification GO:0030278 112 0.014
peptide hormone secretion GO:0030072 109 0.014
gliogenesis GO:0042063 141 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
neuron death GO:0070997 154 0.014
cellular response to abiotic stimulus GO:0071214 56 0.014
camera type eye development GO:0043010 266 0.014
ameboidal type cell migration GO:0001667 128 0.014
regulation of membrane potential GO:0042391 192 0.014
plasma membrane organization GO:0007009 90 0.014
multi multicellular organism process GO:0044706 109 0.014
multi organism behavior GO:0051705 62 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
gonad development GO:0008406 141 0.014
positive regulation of organelle organization GO:0010638 128 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
immune effector process GO:0002252 321 0.014
regulation of gtp catabolic process GO:0033124 113 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
regulation of leukocyte proliferation GO:0070663 121 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
meiotic nuclear division GO:0007126 115 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
regulation of response to wounding GO:1903034 189 0.013
cell adhesion GO:0007155 329 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
spermatid development GO:0007286 108 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
embryonic skeletal system development GO:0048706 120 0.013
cell division GO:0051301 120 0.013
lymphocyte proliferation GO:0046651 164 0.013
learning or memory GO:0007611 148 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
lymphocyte differentiation GO:0030098 242 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
oocyte construction GO:0007308 2 0.013
glial cell differentiation GO:0010001 131 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
transcription from rna polymerase iii promoter GO:0006383 3 0.013
oxidation reduction process GO:0055114 342 0.013
t cell activation GO:0042110 289 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
muscle cell development GO:0055001 133 0.013
forebrain development GO:0030900 302 0.013
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
cell fate determination involved in pattern specification GO:0060582 1 0.012
sensory organ morphogenesis GO:0090596 242 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.012
divalent metal ion transport GO:0070838 172 0.012
cation transport GO:0006812 399 0.012
glycerolipid biosynthetic process GO:0045017 50 0.012
cation homeostasis GO:0055080 212 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
calcium ion homeostasis GO:0055074 127 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of cell growth GO:0001558 91 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
heart process GO:0003015 94 0.012
regulation of cellular component size GO:0032535 121 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
gland development GO:0048732 330 0.012
stem cell proliferation GO:0072089 117 0.012
neural precursor cell proliferation GO:0061351 121 0.012
response to oxygen levels GO:0070482 62 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
compound eye development GO:0048749 1 0.012
pigmentation GO:0043473 71 0.012
angiogenesis GO:0001525 201 0.012
phagocytosis GO:0006909 66 0.012
regulation of cell division GO:0051302 76 0.012
organelle fission GO:0048285 170 0.012
epithelial tube formation GO:0072175 130 0.012
leukocyte proliferation GO:0070661 172 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
positive regulation of protein transport GO:0051222 93 0.011
peptide transport GO:0015833 133 0.011
histone methylation GO:0016571 71 0.011
response to osmotic stress GO:0006970 21 0.011
cell chemotaxis GO:0060326 81 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
multicellular organism growth GO:0035264 161 0.011
circadian rhythm GO:0007623 114 0.011
oocyte axis specification GO:0007309 2 0.011
dna alkylation GO:0006305 43 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
regulation of blood pressure GO:0008217 93 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
negative regulation of protein processing GO:0010955 79 0.011
regulation of chromatin organization GO:1902275 57 0.011
adult locomotory behavior GO:0008344 91 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
protein methylation GO:0006479 81 0.011
lymphocyte homeostasis GO:0002260 64 0.011
response to peptide GO:1901652 136 0.011
innate immune response GO:0045087 157 0.011
regulation of myeloid leukocyte differentiation GO:0002761 58 0.011
response to peptide hormone GO:0043434 127 0.011
zymogen activation GO:0031638 41 0.011
cellular response to peptide GO:1901653 92 0.011
cation transmembrane transport GO:0098655 266 0.011
leukocyte homeostasis GO:0001776 79 0.011
rna processing GO:0006396 105 0.011
regulation of neuron death GO:1901214 134 0.011
nucleoside catabolic process GO:0009164 206 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of t cell activation GO:0050863 170 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
regulation of mitochondrial membrane permeability GO:0046902 17 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
lung development GO:0030324 164 0.011
peptide secretion GO:0002790 114 0.011
sequestering of metal ion GO:0051238 19 0.011
glycerolipid metabolic process GO:0046486 122 0.010
negative regulation of secretion GO:0051048 61 0.010
regulation of protein binding GO:0043393 60 0.010
cellular protein complex disassembly GO:0043624 36 0.010
phospholipid metabolic process GO:0006644 87 0.010
regulation of antimicrobial humoral response GO:0002759 3 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
antimicrobial peptide production GO:0002775 2 0.010
response to insulin GO:0032868 100 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
rab protein signal transduction GO:0032482 1 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
positive regulation of leukocyte proliferation GO:0070665 73 0.010
regulation of chromatin modification GO:1903308 57 0.010
meiotic cell cycle process GO:1903046 77 0.010
negative regulation of cytokine production GO:0001818 84 0.010
protein autophosphorylation GO:0046777 61 0.010

Cobra1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
disease of cellular proliferation DOID:14566 0 0.011