Mus musculus

63 known processes

Aff1

AF4/FMR2 family, member 1

(Aliases: Af4,Rob,AW319193,9630032B01Rik,Mllt2h)

Aff1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
urogenital system development GO:0001655 261 0.511
regionalization GO:0003002 337 0.453
Fly
apoptotic signaling pathway GO:0097190 306 0.422
sensory organ morphogenesis GO:0090596 242 0.359
Fly
ion transmembrane transport GO:0034220 361 0.300
peptidyl amino acid modification GO:0018193 336 0.296
positive regulation of apoptotic signaling pathway GO:2001235 95 0.283
embryonic organ morphogenesis GO:0048562 276 0.278
leukocyte differentiation GO:0002521 342 0.217
ras protein signal transduction GO:0007265 77 0.196
gland development GO:0048732 330 0.194
positive regulation of apoptotic process GO:0043065 217 0.192
dna metabolic process GO:0006259 303 0.190
regulation of cellular ketone metabolic process GO:0010565 66 0.184
stem cell differentiation GO:0048863 268 0.183
cation transmembrane transport GO:0098655 266 0.183
cellular amino acid metabolic process GO:0006520 103 0.180
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.173
negative regulation of molecular function GO:0044092 258 0.169
positive regulation of programmed cell death GO:0043068 218 0.167
regulation of neuron death GO:1901214 134 0.167
regulation of alpha beta t cell differentiation GO:0046637 35 0.167
regulation of cellular response to stress GO:0080135 159 0.161
myotube differentiation GO:0014902 105 0.158
cation transport GO:0006812 399 0.157
circulatory system process GO:0003013 197 0.155
myeloid cell differentiation GO:0030099 233 0.154
muscle system process GO:0003012 141 0.153
regulation of mapk cascade GO:0043408 248 0.152
regulation of cellular amine metabolic process GO:0033238 20 0.151
regulation of cell migration GO:0030334 219 0.150
regulation of hormone levels GO:0010817 211 0.150
epithelial tube morphogenesis GO:0060562 303 0.148
cell type specific apoptotic process GO:0097285 268 0.143
t cell differentiation GO:0030217 174 0.141
regulation of system process GO:0044057 200 0.141
connective tissue development GO:0061448 179 0.141
regulation of apoptotic signaling pathway GO:2001233 197 0.138
neural tube development GO:0021915 160 0.138
cellular response to dna damage stimulus GO:0006974 207 0.136
negative regulation of cellular protein metabolic process GO:0032269 247 0.136
amine metabolic process GO:0009308 45 0.135
transmembrane transport GO:0055085 412 0.135
retina development in camera type eye GO:0060041 119 0.132
t cell activation GO:0042110 289 0.130
cell adhesion GO:0007155 329 0.129
response to growth factor GO:0070848 198 0.128
regulation of body fluid levels GO:0050878 162 0.128
epidermis development GO:0008544 187 0.127
regulation of map kinase activity GO:0043405 120 0.125
cellular amine metabolic process GO:0044106 44 0.124
response to organonitrogen compound GO:0010243 246 0.124
negative regulation of protein modification process GO:0031400 163 0.124
respiratory tube development GO:0030323 167 0.123
positive regulation of cell death GO:0010942 224 0.122
angiogenesis GO:0001525 201 0.121
response to oxidative stress GO:0006979 123 0.121
regulation of hormone secretion GO:0046883 88 0.119
cellular response to growth factor stimulus GO:0071363 197 0.119
regulation of transferase activity GO:0051338 263 0.118
negative regulation of protein metabolic process GO:0051248 282 0.118
embryonic epithelial tube formation GO:0001838 130 0.116
negative regulation of cell proliferation GO:0008285 296 0.114
mesenchyme development GO:0060485 152 0.114
cellular homeostasis GO:0019725 240 0.113
amide transport GO:0042886 138 0.109
negative regulation of cellular amine metabolic process GO:0033239 1 0.108
myeloid leukocyte differentiation GO:0002573 119 0.108
regulation of jun kinase activity GO:0043506 40 0.108
peptide hormone secretion GO:0030072 109 0.108
regulation of cell cycle GO:0051726 281 0.107
regulation of cytokine production GO:0001817 266 0.107
camera type eye development GO:0043010 266 0.107
lymphocyte differentiation GO:0030098 242 0.105
cytokine production GO:0001816 319 0.105
alpha beta t cell differentiation GO:0046632 69 0.101
cell fate commitment GO:0045165 210 0.101
regulation of protein serine threonine kinase activity GO:0071900 157 0.099
wound healing GO:0042060 157 0.099
tube closure GO:0060606 91 0.097
positive regulation of protein phosphorylation GO:0001934 242 0.096
respiratory system development GO:0060541 190 0.095
cellular response to cytokine stimulus GO:0071345 189 0.094
regulation of cysteine type endopeptidase activity GO:2000116 65 0.094
regulation of cellular amino acid metabolic process GO:0006521 5 0.093
muscle tissue development GO:0060537 308 0.093
blastocyst development GO:0001824 80 0.092
cellular lipid metabolic process GO:0044255 323 0.092
posttranscriptional regulation of gene expression GO:0010608 155 0.092
protein autophosphorylation GO:0046777 61 0.091
appendage development GO:0048736 166 0.090
synaptic transmission GO:0007268 329 0.090
muscle cell differentiation GO:0042692 261 0.090
nucleotide metabolic process GO:0009117 332 0.089
neurotransmitter transport GO:0006836 76 0.089
neuron apoptotic process GO:0051402 142 0.089
hindbrain development GO:0030902 128 0.089
skeletal muscle organ development GO:0060538 163 0.088
peptide transport GO:0015833 133 0.088
regulation of neuron apoptotic process GO:0043523 122 0.087
regulation of cell activation GO:0050865 289 0.087
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.086
negative regulation of neuron death GO:1901215 98 0.086
regulation of secretion GO:0051046 274 0.085
circadian regulation of gene expression GO:0032922 48 0.085
regulation of neuron differentiation GO:0045664 281 0.084
hormone secretion GO:0046879 128 0.084
heterocycle catabolic process GO:0046700 280 0.083
negative regulation of phosphorus metabolic process GO:0010563 184 0.081
divalent metal ion transport GO:0070838 172 0.080
protein modification by small protein conjugation GO:0032446 187 0.080
wnt signaling pathway GO:0016055 188 0.079
epithelial tube formation GO:0072175 130 0.079
regulation of cellular catabolic process GO:0031329 242 0.079
jnk cascade GO:0007254 72 0.078
regulation of cell adhesion GO:0030155 154 0.078
regulation of cell motility GO:2000145 236 0.078
leukocyte activation involved in immune response GO:0002366 126 0.077
muscle contraction GO:0006936 101 0.077
muscle cell development GO:0055001 133 0.077
peptide secretion GO:0002790 114 0.077
limb development GO:0060173 166 0.075
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.074
inner ear morphogenesis GO:0042472 101 0.074
negative regulation of protein phosphorylation GO:0001933 126 0.074
limb morphogenesis GO:0035108 149 0.073
cellular ketone metabolic process GO:0042180 84 0.073
neural tube formation GO:0001841 108 0.072
spermatogenesis GO:0007283 284 0.072
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.072
insulin secretion GO:0030073 89 0.072
carboxylic acid transport GO:0046942 100 0.072
regulation of ion transport GO:0043269 215 0.072
intrinsic apoptotic signaling pathway GO:0097193 132 0.071
response to peptide hormone GO:0043434 127 0.071
positive regulation of cellular amine metabolic process GO:0033240 5 0.071
blood vessel morphogenesis GO:0048514 285 0.070
response to metal ion GO:0010038 47 0.070
inorganic cation transmembrane transport GO:0098662 207 0.070
heart morphogenesis GO:0003007 178 0.069
regulation of stress activated mapk cascade GO:0032872 69 0.069
cation homeostasis GO:0055080 212 0.068
carbohydrate metabolic process GO:0005975 230 0.068
small gtpase mediated signal transduction GO:0007264 97 0.068
cartilage development GO:0051216 140 0.068
primary neural tube formation GO:0014020 95 0.068
nitrogen compound transport GO:0071705 271 0.067
regulation of protein kinase activity GO:0045859 232 0.067
rhythmic process GO:0048511 174 0.067
appendage morphogenesis GO:0035107 149 0.067
multicellular organism growth GO:0035264 161 0.067
negative regulation of phosphorylation GO:0042326 166 0.066
positive regulation of cell activation GO:0050867 158 0.066
cytokine mediated signaling pathway GO:0019221 115 0.066
reactive oxygen species metabolic process GO:0072593 84 0.066
organelle localization GO:0051640 179 0.066
hematopoietic progenitor cell differentiation GO:0002244 143 0.066
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.066
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.065
regulation of wnt signaling pathway GO:0030111 123 0.064
epithelial cell development GO:0002064 159 0.064
response to peptide GO:1901652 136 0.064
ossification GO:0001503 216 0.064
regulation of kinase activity GO:0043549 249 0.064
blood circulation GO:0008015 195 0.064
peptidyl serine phosphorylation GO:0018105 74 0.064
placenta development GO:0001890 140 0.064
germ cell development GO:0007281 185 0.063
Mouse
skeletal system development GO:0001501 356 0.063
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.062
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.062
bmp signaling pathway GO:0030509 93 0.062
endothelial cell apoptotic process GO:0072577 9 0.062
cytoplasmic transport GO:0016482 234 0.061
male gamete generation GO:0048232 285 0.060
Mouse
negative regulation of cell motility GO:2000146 61 0.060
negative regulation of cellular component organization GO:0051129 194 0.060
response to light stimulus GO:0009416 135 0.060
negative regulation of nervous system development GO:0051961 156 0.060
alpha beta t cell activation GO:0046631 91 0.060
regulation of neuron projection development GO:0010975 169 0.060
regulation of jnk cascade GO:0046328 62 0.060
negative regulation of immune system process GO:0002683 209 0.060
immune effector process GO:0002252 321 0.060
endocrine system development GO:0035270 98 0.060
extracellular matrix organization GO:0030198 147 0.060
learning or memory GO:0007611 148 0.059
Mouse Fly
protein processing GO:0016485 163 0.059
cell activation involved in immune response GO:0002263 126 0.058
response to organic cyclic compound GO:0014070 198 0.058
lipid catabolic process GO:0016042 69 0.058
cellular response to hormone stimulus GO:0032870 150 0.058
branching morphogenesis of an epithelial tube GO:0048754 159 0.058
regulation of organelle organization GO:0033043 289 0.058
Fly
morphogenesis of a branching epithelium GO:0061138 193 0.057
negative regulation of phosphate metabolic process GO:0045936 184 0.057
aromatic compound catabolic process GO:0019439 286 0.057
regulation of purine nucleotide metabolic process GO:1900542 169 0.057
regulation of organ morphogenesis GO:2000027 144 0.056
purine nucleoside metabolic process GO:0042278 241 0.056
negative regulation of kinase activity GO:0033673 81 0.056
regulation of leukocyte differentiation GO:1902105 159 0.056
nucleoside catabolic process GO:0009164 206 0.056
purine nucleotide metabolic process GO:0006163 302 0.056
ribose phosphate metabolic process GO:0019693 291 0.056
inorganic ion transmembrane transport GO:0098660 234 0.055
fat cell differentiation GO:0045444 160 0.055
oxidation reduction process GO:0055114 342 0.054
peptidyl threonine phosphorylation GO:0018107 31 0.054
protein modification by small protein conjugation or removal GO:0070647 207 0.054
generation of precursor metabolites and energy GO:0006091 103 0.054
stress activated mapk cascade GO:0051403 80 0.053
organic cyclic compound catabolic process GO:1901361 295 0.053
positive regulation of cell development GO:0010720 237 0.053
eye photoreceptor cell differentiation GO:0001754 41 0.053
Fly
regulation of lymphocyte activation GO:0051249 240 0.053
t cell differentiation in thymus GO:0033077 77 0.053
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.053
multi multicellular organism process GO:0044706 109 0.052
regulation of cellular component biogenesis GO:0044087 181 0.052
regulation of endopeptidase activity GO:0052548 89 0.052
stress activated protein kinase signaling cascade GO:0031098 81 0.052
mammary gland morphogenesis GO:0060443 54 0.052
reactive oxygen species biosynthetic process GO:1903409 8 0.051
positive regulation of protein kinase activity GO:0045860 144 0.051
neuron death GO:0070997 154 0.051
single organism cell adhesion GO:0098602 156 0.051
heart process GO:0003015 94 0.051
morphogenesis of embryonic epithelium GO:0016331 159 0.051
organonitrogen compound catabolic process GO:1901565 264 0.051
regulation of stem cell proliferation GO:0072091 78 0.051
eye photoreceptor cell development GO:0042462 31 0.050
Fly
actin cytoskeleton organization GO:0030036 220 0.050
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.050
epithelial cell proliferation GO:0050673 174 0.050
response to inorganic substance GO:0010035 96 0.050
mitotic cell cycle GO:0000278 195 0.050
regulation of transmembrane transport GO:0034762 128 0.049
segmentation GO:0035282 93 0.049
Fly
protein maturation GO:0051604 176 0.049
detection of stimulus GO:0051606 84 0.049
peptidyl serine modification GO:0018209 83 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.049
central nervous system neuron differentiation GO:0021953 162 0.048
platelet activation GO:0030168 40 0.048
cd4 positive alpha beta t cell activation GO:0035710 45 0.048
regulation of peptide transport GO:0090087 91 0.048
positive regulation of transferase activity GO:0051347 167 0.048
cardiac chamber development GO:0003205 108 0.048
locomotory behavior GO:0007626 195 0.047
regulation of response to wounding GO:1903034 189 0.047
negative regulation of intracellular signal transduction GO:1902532 167 0.047
extracellular structure organization GO:0043062 148 0.047
developmental growth involved in morphogenesis GO:0060560 138 0.047
protein ubiquitination GO:0016567 171 0.047
glycosyl compound metabolic process GO:1901657 246 0.047
chromatin modification GO:0016568 187 0.047
divalent inorganic cation transport GO:0072511 178 0.046
purine containing compound catabolic process GO:0072523 213 0.046
regulation of lymphocyte differentiation GO:0045619 107 0.046
striated muscle tissue development GO:0014706 293 0.046
regulation of peptide secretion GO:0002791 77 0.046
nucleoside triphosphate metabolic process GO:0009141 230 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.046
regulation of hydrolase activity GO:0051336 246 0.046
regulation of rho gtpase activity GO:0032319 58 0.045
cellular response to organonitrogen compound GO:0071417 145 0.045
regulation of peptide hormone secretion GO:0090276 75 0.045
regulation of ion transmembrane transport GO:0034765 119 0.045
rho protein signal transduction GO:0007266 32 0.045
regulation of translation GO:0006417 71 0.045
cellular response to biotic stimulus GO:0071216 92 0.045
blood coagulation GO:0007596 76 0.045
regulation of nucleotide metabolic process GO:0006140 169 0.045
maintenance of location GO:0051235 89 0.045
g protein coupled receptor signaling pathway GO:0007186 243 0.045
anion transport GO:0006820 177 0.044
regulation of cytoskeleton organization GO:0051493 122 0.044
Fly
cellular carbohydrate metabolic process GO:0044262 119 0.044
histone modification GO:0016570 159 0.044
regulation of t cell differentiation GO:0045580 83 0.043
purine nucleotide catabolic process GO:0006195 211 0.043
kidney epithelium development GO:0072073 121 0.043
cardiac septum development GO:0003279 59 0.043
chondrocyte differentiation GO:0002062 72 0.043
negative regulation of wnt signaling pathway GO:0030178 73 0.043
organ growth GO:0035265 117 0.042
positive regulation of cytokine production GO:0001819 174 0.042
regulation of cell substrate adhesion GO:0010810 73 0.042
mitotic cell cycle process GO:1903047 159 0.042
tube formation GO:0035148 140 0.042
regulation of secretion by cell GO:1903530 249 0.042
covalent chromatin modification GO:0016569 163 0.042
cellular divalent inorganic cation homeostasis GO:0072503 127 0.041
t cell activation involved in immune response GO:0002286 43 0.041
renal system development GO:0072001 225 0.041
photoreceptor cell differentiation GO:0046530 52 0.041
Fly
lung epithelial cell differentiation GO:0060487 29 0.041
calcium ion homeostasis GO:0055074 127 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
digestive system development GO:0055123 200 0.040
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.040
positive regulation of growth GO:0045927 104 0.040
regulation of myeloid cell differentiation GO:0045637 96 0.040
sensory perception GO:0007600 245 0.040
negative regulation of cell development GO:0010721 169 0.040
lens development in camera type eye GO:0002088 62 0.040
nucleoside metabolic process GO:0009116 246 0.040
response to endoplasmic reticulum stress GO:0034976 53 0.040
positive regulation of t cell activation GO:0050870 101 0.040
neural tube closure GO:0001843 90 0.040
negative regulation of transferase activity GO:0051348 85 0.040
peptidyl tyrosine phosphorylation GO:0018108 143 0.039
morphogenesis of a branching structure GO:0001763 203 0.039
cellular response to lipid GO:0071396 145 0.039
positive regulation of stress activated mapk cascade GO:0032874 48 0.038
ubiquitin dependent protein catabolic process GO:0006511 129 0.038
embryonic placenta development GO:0001892 98 0.038
coagulation GO:0050817 78 0.038
protein localization to organelle GO:0033365 185 0.038
photoreceptor cell development GO:0042461 40 0.038
Fly
translation GO:0006412 93 0.038
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.037
response to radiation GO:0009314 165 0.037
striated muscle contraction GO:0006941 45 0.037
positive regulation of protein modification process GO:0031401 299 0.037
macromolecule catabolic process GO:0009057 281 0.037
lung cell differentiation GO:0060479 30 0.037
development of primary male sexual characteristics GO:0046546 88 0.037
ribonucleoside triphosphate catabolic process GO:0009203 199 0.037
kidney development GO:0001822 213 0.037
negative regulation of map kinase activity GO:0043407 34 0.037
b cell differentiation GO:0030183 78 0.037
alpha amino acid metabolic process GO:1901605 59 0.037
b 1 b cell homeostasis GO:0001922 4 0.037
metal ion homeostasis GO:0055065 189 0.036
regulation of metal ion transport GO:0010959 106 0.036
hemostasis GO:0007599 78 0.036
metencephalon development GO:0022037 89 0.036
ribonucleoside catabolic process GO:0042454 206 0.036
axonogenesis GO:0007409 274 0.036
mapk cascade GO:0000165 281 0.036
lactation GO:0007595 25 0.036
lung development GO:0030324 164 0.035
regulation of cell cycle process GO:0010564 160 0.035
cellular protein catabolic process GO:0044257 155 0.035
negative regulation of apoptotic signaling pathway GO:2001234 104 0.035
negative regulation of synapse assembly GO:0051964 3 0.035
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.035
bone development GO:0060348 120 0.035
cellular response to oxidative stress GO:0034599 76 0.035
labyrinthine layer development GO:0060711 49 0.034
skeletal system morphogenesis GO:0048705 203 0.034
lipid localization GO:0010876 126 0.034
Fly
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.034
leukocyte mediated immunity GO:0002443 174 0.034
protein oligomerization GO:0051259 67 0.034
male sex differentiation GO:0046661 109 0.034
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
digestive tract development GO:0048565 190 0.033
cell substrate adhesion GO:0031589 130 0.033
female sex differentiation GO:0046660 84 0.033
natural killer cell proliferation GO:0001787 3 0.033
positive regulation of mapk cascade GO:0043410 170 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.033
mitochondrion organization GO:0007005 134 0.033
extrinsic apoptotic signaling pathway GO:0097191 126 0.033
inflammatory response GO:0006954 244 0.033
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
adaptive immune response GO:0002250 155 0.033
single organismal cell cell adhesion GO:0016337 131 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.033
stem cell development GO:0048864 219 0.033
cellular component assembly involved in morphogenesis GO:0010927 139 0.033
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.032
forebrain development GO:0030900 302 0.032
mesenchymal cell development GO:0014031 93 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
positive regulation of cellular catabolic process GO:0031331 148 0.032
developmental induction GO:0031128 34 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
adult behavior GO:0030534 135 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.032
positive regulation of potassium ion transport GO:0043268 3 0.032
positive regulation of cell cycle GO:0045787 92 0.031
exocytosis GO:0006887 121 0.031
skin development GO:0043588 220 0.031
regulation of proteolysis GO:0030162 164 0.031
regulation of circadian rhythm GO:0042752 58 0.031
response to insulin GO:0032868 100 0.031
regulation of membrane potential GO:0042391 192 0.031
regulation of bmp signaling pathway GO:0030510 60 0.031
regulation of fibroblast proliferation GO:0048145 34 0.030
notch signaling pathway GO:0007219 71 0.030
retina morphogenesis in camera type eye GO:0060042 45 0.030
actomyosin structure organization GO:0031032 56 0.030
compound eye development GO:0048749 1 0.030
Fly
organelle assembly GO:0070925 177 0.030
hormone metabolic process GO:0042445 86 0.030
chromatin organization GO:0006325 206 0.030
fibroblast migration GO:0010761 21 0.030
actin filament organization GO:0007015 113 0.030
regulation of cell projection organization GO:0031344 206 0.030
regulation of alpha beta t cell activation GO:0046634 53 0.030
synaptic vesicle transport GO:0048489 57 0.030
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.030
circadian rhythm GO:0007623 114 0.030
purine nucleoside catabolic process GO:0006152 205 0.029
intracellular receptor signaling pathway GO:0030522 74 0.029
regulation of neural precursor cell proliferation GO:2000177 70 0.029
regulation of peptidase activity GO:0052547 96 0.029
positive regulation of map kinase activity GO:0043406 84 0.029
positive regulation of nervous system development GO:0051962 221 0.029
cell growth GO:0016049 130 0.029
negative regulation of cell migration GO:0030336 59 0.029
positive regulation of jun kinase activity GO:0043507 30 0.029
monosaccharide metabolic process GO:0005996 106 0.029
positive regulation of lymphocyte activation GO:0051251 140 0.029
gliogenesis GO:0042063 141 0.029
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.029
modification dependent macromolecule catabolic process GO:0043632 133 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
lymphocyte activation involved in immune response GO:0002285 93 0.028
ovarian follicle development GO:0001541 40 0.028
establishment of protein localization to organelle GO:0072594 118 0.028
regulation of protein stability GO:0031647 52 0.028
negative regulation of synaptic vesicle transport GO:1902804 3 0.028
energy derivation by oxidation of organic compounds GO:0015980 77 0.028
fertilization GO:0009566 127 0.028
regulation of muscle contraction GO:0006937 49 0.028
cellular response to molecule of bacterial origin GO:0071219 83 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
glucose homeostasis GO:0042593 128 0.028
gonad development GO:0008406 141 0.028
negative regulation of response to wounding GO:1903035 77 0.028
regulation of binding GO:0051098 111 0.028
purine containing compound metabolic process GO:0072521 311 0.028
development of primary sexual characteristics GO:0045137 143 0.028
voluntary musculoskeletal movement GO:0050882 3 0.028
organic hydroxy compound biosynthetic process GO:1901617 77 0.028
regulation of multi organism process GO:0043900 111 0.027
ameboidal type cell migration GO:0001667 128 0.027
sensory perception of sound GO:0007605 97 0.027
smoothened signaling pathway GO:0007224 105 0.027
protein import into nucleus GO:0006606 95 0.027
cardiac ventricle development GO:0003231 83 0.027
germ line stem cell division GO:0042078 2 0.027
embryonic limb morphogenesis GO:0030326 126 0.027
carbohydrate homeostasis GO:0033500 128 0.027
lipid biosynthetic process GO:0008610 179 0.027
intracellular protein transport GO:0006886 204 0.027
negative regulation of bmp signaling pathway GO:0030514 35 0.027
outflow tract morphogenesis GO:0003151 53 0.027
ear morphogenesis GO:0042471 118 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
regulation of hippo signaling GO:0035330 1 0.027
skeletal muscle cell differentiation GO:0035914 66 0.027
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.026
sensory perception of mechanical stimulus GO:0050954 107 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.026
regulation of chondrocyte differentiation GO:0032330 33 0.026
ear development GO:0043583 200 0.026
response to acid chemical GO:0001101 111 0.026
regulation of cartilage development GO:0061035 44 0.026
regulation of reproductive process GO:2000241 66 0.026
positive regulation of necrotic cell death GO:0010940 1 0.026
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.026
nucleotide catabolic process GO:0009166 217 0.026
stem cell proliferation GO:0072089 117 0.026
protein targeting GO:0006605 143 0.026
oocyte construction GO:0007308 2 0.026
lung epithelium development GO:0060428 37 0.026
positive regulation of stem cell proliferation GO:2000648 59 0.026
thymus development GO:0048538 41 0.026
cellular metal ion homeostasis GO:0006875 151 0.025
protein catabolic process GO:0030163 221 0.025
reactive nitrogen species metabolic process GO:2001057 0 0.025
mammary gland epithelium development GO:0061180 65 0.025
calcium ion transport GO:0006816 159 0.025
organophosphate catabolic process GO:0046434 232 0.025
regulation of angiogenesis GO:0045765 81 0.025
body fluid secretion GO:0007589 53 0.025
response to decreased oxygen levels GO:0036293 59 0.025

Aff1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
nervous system disease DOID:863 0 0.068
disease of cellular proliferation DOID:14566 0 0.055
cancer DOID:162 0 0.045
sensory system disease DOID:0050155 0 0.040
eye and adnexa disease DOID:1492 0 0.032
eye disease DOID:5614 0 0.032
musculoskeletal system disease DOID:17 0 0.030
neuropathy DOID:870 0 0.026