Mus musculus

185 known processes

Dlx5

distal-less homeobox 5

(Aliases: AI385752)

Dlx5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
embryonic organ morphogenesis GO:0048562 276 1.000
skeletal system development GO:0001501 356 1.000
embryonic skeletal system development GO:0048706 120 1.000
Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 1.000
regionalization GO:0003002 337 1.000
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 1.000
Mouse
cerebral cortex neuron differentiation GO:0021895 19 1.000
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 1.000
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 1.000
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 1.000
Mouse
auditory receptor cell fate determination GO:0042668 3 1.000
axon guidance GO:0007411 141 1.000
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 1.000
metanephric capsule specification GO:0072267 1 1.000
pyramidal neuron migration GO:0021852 1 1.000
central nervous system neuron differentiation GO:0021953 162 1.000
Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.999
cell proliferation in hindbrain GO:0021534 10 0.999
appendage morphogenesis GO:0035107 149 0.999
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.999
endodermal cell fate commitment GO:0001711 12 0.999
locus ceruleus development GO:0021703 1 0.999
telencephalon development GO:0021537 186 0.999
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.999
globus pallidus development GO:0021759 2 0.999
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.999
epidermis development GO:0008544 187 0.999
limb development GO:0060173 166 0.999
forebrain neuron differentiation GO:0021879 52 0.999
Mouse
endodermal cell fate specification GO:0001714 4 0.999
hindbrain tangential cell migration GO:0021934 2 0.999
neural tube closure GO:0001843 90 0.999
stem cell development GO:0048864 219 0.999
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.998
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.998
embryonic viscerocranium morphogenesis GO:0048703 8 0.998
gastrulation GO:0007369 116 0.998
forebrain neuron fate commitment GO:0021877 13 0.998
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.998
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.998
pituitary gland development GO:0021983 38 0.997
olfactory bulb interneuron development GO:0021891 7 0.997
embryonic limb morphogenesis GO:0030326 126 0.997
ear morphogenesis GO:0042471 118 0.997
skeletal system morphogenesis GO:0048705 203 0.997
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.997
hindbrain development GO:0030902 128 0.997
subpallium neuron fate commitment GO:0060163 2 0.997
stem cell differentiation GO:0048863 268 0.997
otic placode formation GO:0043049 1 0.997
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.997
negative regulation of heart looping GO:1901208 1 0.997
retinal bipolar neuron differentiation GO:0060040 5 0.997
forebrain regionalization GO:0021871 25 0.996
embryonic heart tube formation GO:0003144 1 0.996
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.996
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.996
limb morphogenesis GO:0035108 149 0.996
olfactory lobe development GO:0021988 32 0.996
Mouse
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.996
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.996
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.996
nephron tubule morphogenesis GO:0072078 68 0.995
somitogenesis GO:0001756 69 0.995
inner ear morphogenesis GO:0042472 101 0.995
pallium development GO:0021543 120 0.995
Mouse
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.995
sinoatrial node cell differentiation GO:0060921 3 0.995
neuron projection guidance GO:0097485 141 0.995
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.995
Mouse
cerebellar granule cell precursor proliferation GO:0021930 10 0.995
cell differentiation in hindbrain GO:0021533 24 0.995
mesenchymal cell development GO:0014031 93 0.994
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.994
formation of primary germ layer GO:0001704 77 0.994
eye photoreceptor cell development GO:0042462 31 0.994
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.993
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.993
diencephalon development GO:0021536 63 0.993
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.993
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.993
metanephric nephron tubule formation GO:0072289 4 0.992
forebrain generation of neurons GO:0021872 63 0.992
Mouse
ear development GO:0043583 200 0.992
positive regulation of stem cell proliferation GO:2000648 59 0.991
positive regulation of transcription by glucose GO:0046016 3 0.990
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.989
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.989
negative regulation of neuron differentiation GO:0045665 101 0.989
cartilage development GO:0051216 140 0.989
Zebrafish Mouse
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.988
cell proliferation in external granule layer GO:0021924 10 0.988
oculomotor nerve morphogenesis GO:0021622 2 0.987
paraxial mesodermal cell differentiation GO:0048342 2 0.986
cell fate commitment GO:0045165 210 0.985
Mouse
appendage development GO:0048736 166 0.985
kidney epithelium development GO:0072073 121 0.985
embryonic appendage morphogenesis GO:0035113 126 0.985
telencephalon regionalization GO:0021978 14 0.985
trachea cartilage morphogenesis GO:0060535 4 0.984
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.984
negative regulation of stem cell maintenance GO:1902455 4 0.983
semicircular canal formation GO:0060876 1 0.983
sensory organ morphogenesis GO:0090596 242 0.983
nephric duct formation GO:0072179 4 0.982
trachea formation GO:0060440 3 0.982
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.981
digestive tract morphogenesis GO:0048546 147 0.980
chondrocyte differentiation GO:0002062 72 0.980
cranial nerve development GO:0021545 41 0.980
Zebrafish
midbrain hindbrain boundary maturation GO:0021732 1 0.980
noradrenergic neuron differentiation GO:0003357 6 0.980
olfactory bulb development GO:0021772 30 0.979
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.979
regulation of glial cell differentiation GO:0045685 41 0.978
Mouse
forebrain neuron development GO:0021884 30 0.978
renal system development GO:0072001 225 0.978
axonogenesis GO:0007409 274 0.978
skin morphogenesis GO:0043589 38 0.977
regulation of vascular wound healing GO:0061043 2 0.977
somite development GO:0061053 81 0.977
mesenchyme development GO:0060485 152 0.976
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.975
subpallium development GO:0021544 20 0.975
Mouse
rhombomere 2 development GO:0021568 2 0.975
specification of organ position GO:0010159 3 0.974
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.974
chondrocyte development GO:0002063 24 0.974
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.974
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.974
mammary placode formation GO:0060596 4 0.972
epithelial tube morphogenesis GO:0060562 303 0.972
forebrain anterior posterior pattern specification GO:0021797 5 0.971
lung induction GO:0060492 3 0.971
hypophysis morphogenesis GO:0048850 3 0.971
spinal cord motor neuron differentiation GO:0021522 35 0.971
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.971
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.970
regulation of astrocyte differentiation GO:0048710 20 0.969
neural crest cell development GO:0014032 48 0.969
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.969
limbic system development GO:0021761 72 0.969
Mouse
primary neural tube formation GO:0014020 95 0.968
branching involved in ureteric bud morphogenesis GO:0001658 56 0.968
embryonic nail plate morphogenesis GO:0035880 3 0.968
mesenchymal cell differentiation GO:0048762 107 0.968
embryonic genitalia morphogenesis GO:0030538 4 0.966
metanephric dct cell differentiation GO:0072240 3 0.966
cerebral cortex radially oriented cell migration GO:0021799 31 0.964
regulation of endodermal cell fate specification GO:0042663 2 0.964
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.963
cell differentiation in spinal cord GO:0021515 53 0.962
mesodermal cell fate commitment GO:0001710 17 0.962
regulation of organ morphogenesis GO:2000027 144 0.961
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.960
retinal ganglion cell axon guidance GO:0031290 18 0.960
bmp signaling pathway GO:0030509 93 0.959
embryonic skeletal joint morphogenesis GO:0060272 11 0.959
anterior commissure morphogenesis GO:0021960 6 0.959
rhombomere development GO:0021546 8 0.958
somatotropin secreting cell differentiation GO:0060126 4 0.958
eye photoreceptor cell differentiation GO:0001754 41 0.958
negative regulation of cell development GO:0010721 169 0.957
Mouse
specification of organ identity GO:0010092 30 0.956
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.956
gland development GO:0048732 330 0.956
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.956
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.956
metanephric capsule formation GO:0072266 1 0.955
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.954
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.953
bmp signaling pathway involved in heart development GO:0061312 2 0.952
cranial nerve formation GO:0021603 4 0.952
Zebrafish
olfactory bulb interneuron differentiation GO:0021889 12 0.950
positive regulation of epithelial cell proliferation GO:0050679 68 0.949
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.949
axial mesodermal cell fate commitment GO:0048322 1 0.948
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.948
carbon catabolite repression of transcription GO:0045013 1 0.948
rhombomere morphogenesis GO:0021593 2 0.947
urogenital system development GO:0001655 261 0.947
negative regulation of axon extension GO:0030517 19 0.947
osteoblast development GO:0002076 17 0.946
forelimb morphogenesis GO:0035136 40 0.946
neuron migration GO:0001764 122 0.945
negative regulation of transcription by glucose GO:0045014 1 0.945
cell proliferation in forebrain GO:0021846 30 0.944
cranial nerve morphogenesis GO:0021602 26 0.944
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 9 0.943
stem cell maintenance GO:0019827 130 0.943
bone development GO:0060348 120 0.941
neural tube formation GO:0001841 108 0.941
odontogenesis GO:0042476 78 0.941
Mouse
astrocyte fate commitment GO:0060018 4 0.940
prostate gland morphogenesis GO:0060512 32 0.939
regulation of bmp signaling pathway GO:0030510 60 0.939
embryonic epithelial tube formation GO:0001838 130 0.937
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.936
negative regulation of gastrulation GO:2000542 3 0.936
cerebellum formation GO:0021588 1 0.935
rhombomere 3 morphogenesis GO:0021658 2 0.934
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.933
noradrenergic neuron development GO:0003358 3 0.931
cochlea morphogenesis GO:0090103 22 0.931
branching morphogenesis of an epithelial tube GO:0048754 159 0.931
cell fate specification GO:0001708 72 0.930
glial cell differentiation GO:0010001 131 0.929
Mouse
pancreatic pp cell fate commitment GO:0003329 2 0.929
smoothened signaling pathway GO:0007224 105 0.928
negative regulation of glial cell differentiation GO:0045686 21 0.927
Mouse
neural tube patterning GO:0021532 43 0.926
branch elongation involved in salivary gland morphogenesis GO:0060667 2 0.926
dichotomous subdivision of terminal units involved in ureteric bud branching GO:0060678 1 0.925
forebrain development GO:0030900 302 0.923
Mouse
hippocampus development GO:0021766 52 0.923
Mouse
corticotropin hormone secreting cell differentiation GO:0060128 3 0.922
epithelial to mesenchymal transition GO:0001837 47 0.921
cartilage morphogenesis GO:0060536 11 0.918
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.916
cerebellum development GO:0021549 77 0.915
trophectodermal cell differentiation GO:0001829 21 0.914
epithelial cell development GO:0002064 159 0.914
regulation of heart morphogenesis GO:2000826 22 0.913
ventricular zone neuroblast division GO:0021847 3 0.913
neuron projection extension GO:1990138 64 0.912
neuron fate specification GO:0048665 30 0.911
visceral motor neuron differentiation GO:0021524 3 0.910
paraxial mesodermal cell fate commitment GO:0048343 2 0.910
axis elongation involved in somitogenesis GO:0090245 4 0.909
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.908
epithelial tube formation GO:0072175 130 0.907
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.906
sensory perception GO:0007600 245 0.906
neural crest cell differentiation GO:0014033 54 0.904
negative regulation of endodermal cell differentiation GO:1903225 1 0.904
mesenchymal to epithelial transition GO:0060231 12 0.903
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.901
ectoderm formation GO:0001705 3 0.901
renal capsule specification GO:0072130 1 0.900
tendon formation GO:0035992 4 0.900
preganglionic parasympathetic nervous system development GO:0021783 17 0.900
regulation of skeletal muscle cell differentiation GO:2001014 11 0.898
neural tube development GO:0021915 160 0.897
stem cell proliferation GO:0072089 117 0.897
primitive streak formation GO:0090009 10 0.896
medulla oblongata development GO:0021550 3 0.895
outflow tract morphogenesis GO:0003151 53 0.894
regulation of smoothened signaling pathway GO:0008589 58 0.892
lateral motor column neuron migration GO:0097477 3 0.892
dopaminergic neuron differentiation GO:0071542 14 0.891
forebrain cell migration GO:0021885 58 0.891
tube formation GO:0035148 140 0.891
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.889
prostate gland development GO:0030850 48 0.889
dorsal ventral neural tube patterning GO:0021904 28 0.886
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 0.885
cerebral cortex gabaergic interneuron development GO:0021894 6 0.884
negative regulation of neuron projection development GO:0010977 50 0.884
ureteric bud development GO:0001657 94 0.882
cerebral cortex cell migration GO:0021795 44 0.879
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.878
optic vesicle morphogenesis GO:0003404 2 0.875
cell migration in hindbrain GO:0021535 16 0.875
vascular wound healing GO:0061042 3 0.873
embryonic forelimb morphogenesis GO:0035115 32 0.873
regulation of stem cell differentiation GO:2000736 50 0.870
glomerular epithelial cell differentiation GO:0072311 10 0.869
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.869
forebrain ventricular zone progenitor cell division GO:0021869 6 0.869
embryonic placenta development GO:0001892 98 0.866
brain segmentation GO:0035284 3 0.864
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.864
central nervous system neuron development GO:0021954 67 0.862
rhombomere 3 development GO:0021569 4 0.861
submandibular salivary gland formation GO:0060661 1 0.861
middle ear morphogenesis GO:0042474 23 0.861
regulation of oligodendrocyte differentiation GO:0048713 23 0.860
Mouse
mesoderm formation GO:0001707 62 0.858
nerve development GO:0021675 67 0.854
Zebrafish
bone morphogenesis GO:0060349 78 0.852
renal vesicle induction GO:0072034 3 0.851
epithelial cell morphogenesis GO:0003382 41 0.849
embryonic hindlimb morphogenesis GO:0035116 32 0.849
cardiac epithelial to mesenchymal transition GO:0060317 18 0.848
camera type eye development GO:0043010 266 0.847
cerebral cortex tangential migration GO:0021800 7 0.847
glomerular mesangial cell development GO:0072144 3 0.847
biomineral tissue development GO:0031214 64 0.845
axial mesoderm formation GO:0048320 3 0.844
neural crest cell fate commitment GO:0014034 1 0.844
heart field specification GO:0003128 6 0.844
spinal cord association neuron differentiation GO:0021527 14 0.840
ossification GO:0001503 216 0.840
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.840
ventricular septum morphogenesis GO:0060412 27 0.840
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.839
embryonic digit morphogenesis GO:0042733 56 0.838
cardiac muscle cell differentiation GO:0055007 69 0.838
hindbrain morphogenesis GO:0021575 46 0.838
camera type eye photoreceptor cell differentiation GO:0060219 15 0.836
optic nerve structural organization GO:0021633 2 0.824
spinal cord motor neuron cell fate specification GO:0021520 13 0.823
atrioventricular bundle cell differentiation GO:0003167 1 0.821
segmentation GO:0035282 93 0.820
lymphocyte differentiation GO:0030098 242 0.820
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.816
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.816
mammary gland morphogenesis GO:0060443 54 0.814
mammary gland bud formation GO:0060615 2 0.810
metencephalon development GO:0022037 89 0.810
branch elongation involved in ureteric bud branching GO:0060681 3 0.809
granulosa cell differentiation GO:0060014 1 0.807
salivary gland morphogenesis GO:0007435 33 0.806
negative regulation of astrocyte differentiation GO:0048712 10 0.806
regulation of neuron maturation GO:0014041 5 0.806
parasympathetic nervous system development GO:0048486 19 0.805
regulation of mesodermal cell fate specification GO:0042661 5 0.805
digestive system development GO:0055123 200 0.804
negative regulation of endodermal cell fate specification GO:0042664 1 0.801
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.799
palate development GO:0060021 76 0.798
positive regulation of glial cell differentiation GO:0045687 21 0.796
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.794
telencephalon cell migration GO:0022029 55 0.793
closure of optic fissure GO:0061386 2 0.791
face morphogenesis GO:0060325 29 0.791
pronephric field specification GO:0039003 2 0.791
autonomic nervous system development GO:0048483 43 0.790
cell proliferation in midbrain GO:0033278 2 0.788
semicircular canal morphogenesis GO:0048752 7 0.787
t cell differentiation GO:0030217 174 0.787
regulation of mesenchymal cell apoptotic process GO:2001053 14 0.784
prostate gland stromal morphogenesis GO:0060741 2 0.782
inner ear receptor cell differentiation GO:0060113 61 0.781
astrocyte differentiation GO:0048708 43 0.778
regulation of auditory receptor cell differentiation GO:0045607 4 0.777
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.777
regulation of stem cell proliferation GO:0072091 78 0.776
skin development GO:0043588 220 0.776
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.775
odontogenesis of dentin containing tooth GO:0042475 66 0.774
Mouse
his purkinje system cell differentiation GO:0060932 2 0.774
regulation of chondrocyte differentiation GO:0032330 33 0.771
regulation of osteoblast differentiation GO:0045667 67 0.770
Rat
lung epithelial cell differentiation GO:0060487 29 0.769
developmental growth involved in morphogenesis GO:0060560 138 0.768
connective tissue development GO:0061448 179 0.765
Zebrafish Mouse
pyramidal neuron development GO:0021860 8 0.764
carbon catabolite activation of transcription GO:0045991 4 0.762
regulation of cardiac chamber formation GO:1901210 1 0.761
outflow tract septum morphogenesis GO:0003148 11 0.760
pons development GO:0021548 13 0.758
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.757
atrial septum primum morphogenesis GO:0003289 3 0.755
midbrain hindbrain boundary development GO:0030917 9 0.753
morphogenesis of embryonic epithelium GO:0016331 159 0.752
adenohypophysis development GO:0021984 14 0.749
neural crest formation GO:0014029 2 0.747
metanephric nephron tubule epithelial cell differentiation GO:0072257 5 0.743
regulation of transcription involved in cell fate commitment GO:0060850 15 0.742
Mouse
positive regulation of osteoblast differentiation GO:0045669 34 0.735
Rat
negative regulation of prostatic bud formation GO:0060686 4 0.730
leukocyte differentiation GO:0002521 342 0.725
notochord formation GO:0014028 5 0.725
central nervous system neuron axonogenesis GO:0021955 28 0.723
cerebellar granule cell differentiation GO:0021707 9 0.723
oligodendrocyte development GO:0014003 20 0.722
respiratory system development GO:0060541 190 0.722
regulation of odontogenesis GO:0042481 18 0.721
somatic stem cell maintenance GO:0035019 47 0.721
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.721
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.719
face development GO:0060324 38 0.718
regulation of heart looping GO:1901207 1 0.717
interneuron migration from the subpallium to the cortex GO:0021830 7 0.717
substrate independent telencephalic tangential migration GO:0021826 8 0.716
cardiac left ventricle formation GO:0003218 1 0.715
renal capsule formation GO:0072129 1 0.714
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.711
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.710
endocardial cushion formation GO:0003272 13 0.707
negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 2 0.704
metanephros morphogenesis GO:0003338 24 0.704
organ growth GO:0035265 117 0.703
angiogenesis GO:0001525 201 0.703
endoderm formation GO:0001706 20 0.701
retina development in camera type eye GO:0060041 119 0.701
cranial suture morphogenesis GO:0060363 8 0.701
hindlimb morphogenesis GO:0035137 42 0.700
positive regulation of vascular wound healing GO:0035470 1 0.698
regulation of cartilage development GO:0061035 44 0.697
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.695
blood vessel morphogenesis GO:0048514 285 0.684
gabaergic neuron differentiation GO:0097154 11 0.684
Mouse
mesonephros development GO:0001823 97 0.683
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.681
forebrain radial glial cell differentiation GO:0021861 4 0.681
hypothalamus development GO:0021854 16 0.679
regulation of neuron projection development GO:0010975 169 0.678
negative regulation of kidney development GO:0090185 15 0.677
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.676
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.675
regulation of endodermal cell differentiation GO:1903224 2 0.674
cartilage condensation GO:0001502 18 0.674
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.670
positive regulation of tendon cell differentiation GO:2001051 1 0.668
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.668
negative regulation of cell fate specification GO:0009996 4 0.668
epithelial cell differentiation involved in kidney development GO:0035850 23 0.668
regulation of gastrulation GO:0010470 16 0.666
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.665
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.660
regulation of tongue muscle cell differentiation GO:2001035 2 0.658
cell type specific apoptotic process GO:0097285 268 0.655
cardiac chamber morphogenesis GO:0003206 93 0.650
mesoderm development GO:0007498 100 0.650
lateral line system development GO:0048925 1 0.648
neuroblast differentiation GO:0014016 2 0.647
diencephalon morphogenesis GO:0048852 6 0.647
negative regulation of chondrocyte differentiation GO:0032331 13 0.647
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.646
axial mesodermal cell differentiation GO:0048321 1 0.646
positive regulation of wnt signaling pathway GO:0030177 45 0.642
central nervous system projection neuron axonogenesis GO:0021952 21 0.642
hematopoietic progenitor cell differentiation GO:0002244 143 0.642
blastocyst formation GO:0001825 33 0.640
carbohydrate homeostasis GO:0033500 128 0.639
photoreceptor cell development GO:0042461 40 0.639
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.637
kidney development GO:0001822 213 0.635
metanephric renal vesicle morphogenesis GO:0072283 12 0.632
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.632
axonogenesis involved in innervation GO:0060385 5 0.631
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.629
positive regulation of transcription via serum response element binding GO:0010735 1 0.629
mesodermal cell differentiation GO:0048333 22 0.627
olfactory pit development GO:0060166 3 0.626
oligodendrocyte differentiation GO:0048709 53 0.625
Mouse
cerebral cortex radial glia guided migration GO:0021801 17 0.624
negative regulation of epidermis development GO:0045683 9 0.621
positive regulation of tongue muscle cell differentiation GO:2001037 2 0.621
columnar cuboidal epithelial cell development GO:0002066 29 0.620
cerebral cortex development GO:0021987 86 0.620
vagus nerve development GO:0021564 3 0.618
renal vesicle morphogenesis GO:0072077 15 0.616
regulation of cell fate commitment GO:0010453 19 0.616
cell differentiation involved in embryonic placenta development GO:0060706 26 0.615
metanephric mesenchymal cell differentiation GO:0072162 3 0.615
pattern specification involved in metanephros development GO:0072268 4 0.611
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 0.610
vagus nerve morphogenesis GO:0021644 2 0.603
gliogenesis GO:0042063 141 0.597
Mouse
blastocyst development GO:0001824 80 0.595
ventral spinal cord interneuron specification GO:0021521 11 0.594
negative regulation of branching involved in ureteric bud morphogenesis GO:0090191 4 0.594
inner cell mass cellular morphogenesis GO:0001828 1 0.594
positive regulation of cardiac muscle tissue development GO:0055025 19 0.593
digestive tract development GO:0048565 190 0.591
spinal cord motor neuron migration GO:0097476 4 0.589
mesoderm morphogenesis GO:0048332 64 0.584
morphogenesis of a branching structure GO:0001763 203 0.584
Mouse
exocrine system development GO:0035272 45 0.571
cell maturation GO:0048469 127 0.569
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.569
embryonic camera type eye development GO:0031076 36 0.566
regulation of epithelial cell proliferation GO:0050678 141 0.564
response to bmp GO:0071772 14 0.564
regulation of neuron apoptotic process GO:0043523 122 0.563
positive regulation of heart growth GO:0060421 18 0.562
mesonephric duct morphogenesis GO:0072180 4 0.561
negative regulation of glomerular mesangial cell proliferation GO:0072125 1 0.559
tube closure GO:0060606 91 0.552
thalamus development GO:0021794 11 0.552
embryonic skeletal joint development GO:0072498 13 0.547
prostate glandular acinus development GO:0060525 12 0.547
muscle tissue morphogenesis GO:0060415 53 0.545
cardiac right ventricle formation GO:0003219 3 0.545
positive regulation of hh target transcription factor activity GO:0007228 3 0.544
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.543
regulation of cardiac chamber morphogenesis GO:1901219 2 0.543
positive regulation of neuron differentiation GO:0045666 141 0.543
positive regulation of cell death GO:0010942 224 0.543
rostrocaudal neural tube patterning GO:0021903 12 0.540
peripheral nervous system neuron development GO:0048935 9 0.538
nephrogenic mesenchyme development GO:0072076 3 0.538
negative regulation of nervous system development GO:0051961 156 0.537
Mouse
trophectodermal cellular morphogenesis GO:0001831 3 0.535
regulation of retina development in camera type eye GO:1902866 3 0.534
lung cell differentiation GO:0060479 30 0.534
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.534
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.534
lung development GO:0030324 164 0.532
establishment of neuroblast polarity GO:0045200 1 0.529

Dlx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.759
musculoskeletal system disease DOID:17 0 0.759
mouth disease DOID:403 0 0.537
tooth disease DOID:1091 0 0.537
gastrointestinal system disease DOID:77 0 0.537