|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.856
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.856
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.814
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.804
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.735
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.730
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.728
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.698
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.679
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.653
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.652
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.631
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.619
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.606
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.599
|
Mouse Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.593
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.589
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.578
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.548
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.546
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.539
|
Fly |
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.535
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.535
|
Mouse Fly |
|
|
t cell activation
|
GO:0042110 |
289 |
0.525
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.522
|
Mouse Fly |
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.518
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.518
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.500
|
Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.497
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.482
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.473
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.471
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.467
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.466
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.465
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.465
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.443
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.435
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.431
|
Mouse |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.430
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.426
|
Mouse Fly |
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.416
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.413
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.400
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.396
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.395
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.393
|
Mouse |
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.387
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.382
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.375
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.373
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.370
|
|
|
|
activation of ras gtpase activity
|
GO:0032856 |
11 |
0.370
|
Fly |
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.370
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.368
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.366
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.366
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.363
|
|
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.359
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.358
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.351
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.340
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.340
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.339
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.338
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.335
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.332
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.329
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.326
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.321
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.320
|
Mouse Fly |
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.318
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.313
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.305
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.304
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.298
|
Fly |
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.298
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.298
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.295
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.292
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.292
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.291
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.291
|
|
|
|
norepinephrine transport
|
GO:0015874 |
2 |
0.287
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.284
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.282
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.281
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.273
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.271
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.270
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.267
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.265
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.264
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.261
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.261
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.259
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.259
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.259
|
|
|
|
triglyceride homeostasis
|
GO:0070328 |
15 |
0.259
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.257
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.255
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.254
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.253
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.252
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.252
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.251
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.251
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.249
|
Fly |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.249
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.247
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.247
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.245
|
|
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.245
|
Fly |
|
|
sensory perception
|
GO:0007600 |
245 |
0.244
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.238
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.238
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.238
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.238
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.236
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.231
|
|
|
|
adipose tissue development
|
GO:0060612 |
25 |
0.229
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.226
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.226
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.226
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.224
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.223
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.221
|
Mouse Fly |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.218
|
Mouse Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.216
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.215
|
Fly |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.214
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.214
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.213
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.210
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.208
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.207
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.203
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.203
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.202
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.201
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.201
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.199
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.199
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.198
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.198
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.198
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.195
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.194
|
Fly |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.190
|
Mouse |
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.190
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.190
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.190
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.190
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.189
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.189
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.189
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.183
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.182
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.182
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.181
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.180
|
Mouse |
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.177
|
Mouse |
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.176
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.173
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.173
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.171
|
|
|
|
regulation of renal output by angiotensin
|
GO:0002019 |
2 |
0.171
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.169
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.169
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.168
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.167
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.165
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.163
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.163
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.162
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.161
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.161
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.158
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.157
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.156
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.156
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.156
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.156
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.153
|
|
|
|
renal sodium excretion
|
GO:0035812 |
3 |
0.152
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.152
|
Mouse |
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.151
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.151
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.150
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.150
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.150
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.149
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.146
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.145
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.145
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.145
|
|
|
|
superoxide anion generation
|
GO:0042554 |
11 |
0.145
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.144
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.143
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.143
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.141
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.141
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.141
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.140
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.140
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.140
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.138
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.138
|
Mouse Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.136
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.136
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
8 |
0.135
|
|
|
|
dopamine catabolic process
|
GO:0042420 |
4 |
0.134
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.133
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.131
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.131
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.130
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.130
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.130
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.129
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.128
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.127
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.126
|
|
|
|
regulation of protein kinase c activity
|
GO:1900019 |
1 |
0.125
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.125
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.124
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.123
|
Human |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.122
|
|
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.122
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.121
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.120
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.120
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.119
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.119
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.119
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.117
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.117
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.117
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.117
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.116
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.116
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.116
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.116
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.115
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.115
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.112
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.112
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.110
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.108
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.108
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.108
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.108
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.108
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.107
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.106
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.106
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.106
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.105
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.105
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.105
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.105
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.103
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.103
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.103
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.102
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.102
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
7 |
0.102
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.101
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.101
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.100
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.100
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.100
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.100
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.099
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.099
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.099
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.098
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.098
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.097
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.097
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.096
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.096
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.096
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.095
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.095
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.095
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.094
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.094
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.093
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.093
|
|
|
|
negative regulation of neurotransmitter transport
|
GO:0051589 |
7 |
0.093
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.093
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.092
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.092
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.092
|
|
|
|
negative regulation of fibroblast migration
|
GO:0010764 |
2 |
0.091
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.091
|
|
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
1 |
0.091
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.091
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.090
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.090
|
|
|
|
mammary gland involution
|
GO:0060056 |
9 |
0.090
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.090
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.090
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.090
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.090
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.089
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.089
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.088
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.088
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.088
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.088
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.088
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.088
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.087
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.087
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.087
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.087
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.087
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.086
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.086
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.086
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.086
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.085
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.085
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.084
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.084
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.084
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.084
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.083
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.083
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.083
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.082
|
|
|
|
regulation of activation of janus kinase activity
|
GO:0010533 |
1 |
0.082
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.082
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
11 |
0.082
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.081
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.080
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.080
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.080
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.080
|
|
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.079
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.079
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.079
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.078
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.078
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.078
|
|
|
|
regulation of gluconeogenesis
|
GO:0006111 |
30 |
0.078
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.077
|
|
|
|
regulation of superoxide anion generation
|
GO:0032928 |
4 |
0.077
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.076
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.076
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.076
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.076
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.075
|
|
|
|
renin angiotensin regulation of aldosterone production
|
GO:0002018 |
3 |
0.075
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.075
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.074
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.074
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.074
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.073
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.073
|
Worm |
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.072
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.072
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.072
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.072
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.072
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.072
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.071
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.071
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.071
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.071
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.071
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.071
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.071
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.071
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.071
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.070
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.070
|
|
|
|
acylglycerol homeostasis
|
GO:0055090 |
16 |
0.070
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.070
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.069
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.069
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.069
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.069
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.069
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.068
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.068
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
55 |
0.068
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.068
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.068
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.068
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.067
|
|
|
|
organic hydroxy compound catabolic process
|
GO:1901616 |
25 |
0.067
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.067
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.067
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.067
|
Fly |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.066
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.066
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.065
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.065
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.064
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.064
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.064
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.064
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.064
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.063
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.063
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.063
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.063
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.063
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.063
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.062
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.062
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.062
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.062
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.062
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.061
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.061
|
Mouse |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.061
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.061
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.061
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.060
|
|
|
|
pituitary gland development
|
GO:0021983 |
38 |
0.060
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.060
|
|
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
14 |
0.059
|
Worm |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.059
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.059
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.059
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.059
|
|
|
|
response to pain
|
GO:0048265 |
26 |
0.058
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.058
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.058
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
18 |
0.058
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.058
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.057
|
Fly |
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.057
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.057
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.057
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.057
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.057
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.057
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.057
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.056
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.056
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.056
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.056
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.056
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
17 |
0.056
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.056
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.056
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.055
|
|
|
|
embryonic placenta morphogenesis
|
GO:0060669 |
25 |
0.055
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.055
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.055
|
|
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.055
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.055
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.055
|
|
|
|
astrocyte development
|
GO:0014002 |
12 |
0.055
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
4 |
0.054
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.054
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.054
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.053
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.053
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.053
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.053
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.053
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.052
|
|
|
|
cellular response to vitamin d
|
GO:0071305 |
2 |
0.052
|
|
|
|
regulation of mammary gland involution
|
GO:1903519 |
4 |
0.052
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.052
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.052
|
Human |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.052
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.052
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
51 |
0.051
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.051
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.051
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.051
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.051
|
|
|
|
response to dexamethasone
|
GO:0071548 |
8 |
0.051
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.051
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.051
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.051
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.050
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.050
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
22 |
0.050
|
|