Mus musculus

0 known processes

Smpd4

sphingomyelin phosphodiesterase 4

(Aliases: 4122402O22Rik,mKIAA1418)

Smpd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 170 0.068
cytoplasmic transport GO:0016482 234 0.053
microtubule based process GO:0007017 236 0.053
regulation of histone h3 k36 methylation GO:0000414 1 0.047
nuclear division GO:0000280 158 0.043
nucleocytoplasmic transport GO:0006913 139 0.042
meiotic cell cycle GO:0051321 122 0.040
macromolecule methylation GO:0043414 120 0.039
apoptotic signaling pathway GO:0097190 306 0.038
intracellular protein transport GO:0006886 204 0.037
regulation of cellular component biogenesis GO:0044087 181 0.037
regulation of organelle organization GO:0033043 289 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.035
regulation of cell cycle process GO:0010564 160 0.034
nuclear transport GO:0051169 139 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
protein targeting GO:0006605 143 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
cellular ketone metabolic process GO:0042180 84 0.030
methylation GO:0032259 134 0.030
mitotic cell cycle GO:0000278 195 0.030
organonitrogen compound catabolic process GO:1901565 264 0.029
regulation of cell cycle GO:0051726 281 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.028
organelle assembly GO:0070925 177 0.028
membrane organization GO:0061024 245 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
nitrogen compound transport GO:0071705 271 0.027
peptidyl amino acid modification GO:0018193 336 0.026
maintenance of location GO:0051235 89 0.026
heterocycle catabolic process GO:0046700 280 0.026
germ cell development GO:0007281 185 0.026
protein import GO:0017038 101 0.026
cellular amine metabolic process GO:0044106 44 0.025
amine metabolic process GO:0009308 45 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
cellular response to dna damage stimulus GO:0006974 207 0.024
regulation of cell activation GO:0050865 289 0.024
regulation of protein localization GO:0032880 231 0.024
regulation of lymphocyte activation GO:0051249 240 0.023
intracellular mrna localization GO:0008298 4 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
protein alkylation GO:0008213 81 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
rna splicing GO:0008380 54 0.023
aromatic compound catabolic process GO:0019439 286 0.023
nucleus organization GO:0006997 45 0.023
engulfment of apoptotic cell GO:0043652 3 0.022
gene silencing GO:0016458 38 0.022
regulation of membrane potential GO:0042391 192 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
regulation of hydrolase activity GO:0051336 246 0.022
nucleoside metabolic process GO:0009116 246 0.022
meiotic nuclear division GO:0007126 115 0.021
histone methylation GO:0016571 71 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
regulation of antimicrobial humoral response GO:0002759 3 0.021
mrna processing GO:0006397 63 0.021
histone h3 k4 methylation GO:0051568 23 0.021
oocyte axis specification GO:0007309 2 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
macromolecule catabolic process GO:0009057 281 0.020
chromatin organization GO:0006325 206 0.020
histone lysine methylation GO:0034968 50 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
transmembrane transport GO:0055085 412 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
b cell activation GO:0042113 161 0.020
spermatogenesis GO:0007283 284 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
protein import into nucleus GO:0006606 95 0.019
mitotic cell cycle process GO:1903047 159 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
purine containing compound metabolic process GO:0072521 311 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.019
protein localization to nucleus GO:0034504 121 0.019
dna recombination GO:0006310 92 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
mrna metabolic process GO:0016071 84 0.019
skeletal system development GO:0001501 356 0.019
immune effector process GO:0002252 321 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
antimicrobial peptide biosynthetic process GO:0002777 2 0.019
multicellular organismal signaling GO:0035637 91 0.019
protein localization to organelle GO:0033365 185 0.019
nuclear import GO:0051170 95 0.019
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.019
rna processing GO:0006396 105 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
action potential GO:0001508 78 0.018
ion transmembrane transport GO:0034220 361 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
regulation of intracellular transport GO:0032386 159 0.018
pole plasm assembly GO:0007315 2 0.018
rna localization GO:0006403 23 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
oocyte anterior posterior axis specification GO:0007314 2 0.018
oxidation reduction process GO:0055114 342 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
single organism nuclear import GO:1902593 95 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
covalent chromatin modification GO:0016569 163 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
immunoglobulin production GO:0002377 73 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
ribonucleotide catabolic process GO:0009261 208 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
cajal body organization GO:0030576 1 0.016
male gamete generation GO:0048232 285 0.016
cation transport GO:0006812 399 0.016
regulation of histone methylation GO:0031060 30 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
protein ubiquitination GO:0016567 171 0.016
homeostasis of number of cells GO:0048872 210 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
protein maturation GO:0051604 176 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
purine containing compound catabolic process GO:0072523 213 0.015
anatomical structure homeostasis GO:0060249 145 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
cation transmembrane transport GO:0098655 266 0.015
organophosphate catabolic process GO:0046434 232 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
somatic cell dna recombination GO:0016444 51 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
positive regulation of protein modification process GO:0031401 299 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
peptidyl lysine modification GO:0018205 77 0.015
positive regulation of cell activation GO:0050867 158 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of establishment of protein localization GO:0070201 181 0.014
dna replication GO:0006260 52 0.014
organelle localization GO:0051640 179 0.014
lipid biosynthetic process GO:0008610 179 0.014
mrna transport GO:0051028 13 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
mrna splicing via spliceosome GO:0000398 43 0.014
cellular protein complex assembly GO:0043623 116 0.014
chromatin modification GO:0016568 187 0.014
nucleoside catabolic process GO:0009164 206 0.014
regulation of dna recombination GO:0000018 34 0.014
lateral inhibition GO:0046331 1 0.014
positive regulation of cell death GO:0010942 224 0.014
cardiac muscle cell contraction GO:0086003 7 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
response to organonitrogen compound GO:0010243 246 0.013
microtubule nucleation GO:0007020 2 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
protein acylation GO:0043543 64 0.013
establishment or maintenance of cell polarity GO:0007163 86 0.013
protein processing GO:0016485 163 0.013
cellular amide metabolic process GO:0043603 58 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
gonad development GO:0008406 141 0.013
immunoglobulin mediated immune response GO:0016064 69 0.013
transmission of nerve impulse GO:0019226 76 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
ras protein signal transduction GO:0007265 77 0.013
dna metabolic process GO:0006259 303 0.013
developmental maturation GO:0021700 193 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
positive regulation of histone methylation GO:0031062 16 0.013
regulation of antimicrobial peptide production GO:0002784 1 0.013
protein catabolic process GO:0030163 221 0.013
regulation of chromosome organization GO:0033044 83 0.012
positive regulation of organelle organization GO:0010638 128 0.012
organic anion transport GO:0015711 137 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
regulation of transferase activity GO:0051338 263 0.012
nuclear export GO:0051168 34 0.012
female gamete generation GO:0007292 74 0.012
meiotic cell cycle process GO:1903046 77 0.012
mitochondrion organization GO:0007005 134 0.012
cell activation involved in immune response GO:0002263 126 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
actin filament based movement GO:0030048 23 0.012
positive regulation of b cell activation GO:0050871 49 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
regulation of b cell activation GO:0050864 81 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
positive regulation of immune effector process GO:0002699 107 0.012
dephosphorylation GO:0016311 129 0.012
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.012
histone h3 k36 methylation GO:0010452 6 0.012
male meiosis GO:0007140 37 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
regulation of cellular response to stress GO:0080135 159 0.012
leukocyte differentiation GO:0002521 342 0.012
response to organic cyclic compound GO:0014070 198 0.012
cellular homeostasis GO:0019725 240 0.011
regionalization GO:0003002 337 0.011
response to radiation GO:0009314 165 0.011
b cell mediated immunity GO:0019724 71 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
meiosis i GO:0007127 60 0.011
somatic diversification of immunoglobulins GO:0016445 43 0.011
connective tissue development GO:0061448 179 0.011
positive regulation of antimicrobial humoral response GO:0002760 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
nucleotide metabolic process GO:0009117 332 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
camera type eye development GO:0043010 266 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.011
neuronal action potential GO:0019228 54 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
axonogenesis GO:0007409 274 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
endomembrane system organization GO:0010256 147 0.011
gtp metabolic process GO:0046039 144 0.011
cofactor metabolic process GO:0051186 80 0.011
cell adhesion GO:0007155 329 0.011
rna catabolic process GO:0006401 29 0.010
response to inorganic substance GO:0010035 96 0.010
response to growth factor GO:0070848 198 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
regulation of homeostatic process GO:0032844 182 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
regulation of cell migration GO:0030334 219 0.010
protein methylation GO:0006479 81 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
regulation of kinase activity GO:0043549 249 0.010
response to extracellular stimulus GO:0009991 127 0.010
development of primary sexual characteristics GO:0045137 143 0.010

Smpd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
retinal disease DOID:5679 0 0.016
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
retinal degeneration DOID:8466 0 0.015
central nervous system disease DOID:331 0 0.014
retinitis pigmentosa DOID:10584 0 0.010