Mus musculus

69 known processes

Smpd3

sphingomyelin phosphodiesterase 3, neutral

(Aliases: AI427456,AW537966,4631433G07Rik,fro,nSMase2)

Smpd3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 356 0.921
appendage development GO:0048736 166 0.715
skeletal system morphogenesis GO:0048705 203 0.687
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.630
bone development GO:0060348 120 0.553
limb development GO:0060173 166 0.442
wnt signaling pathway GO:0016055 188 0.440
proteoglycan metabolic process GO:0006029 38 0.427
limb morphogenesis GO:0035108 149 0.424
response to fibroblast growth factor GO:0071774 47 0.418
regulation of canonical wnt signaling pathway GO:0060828 82 0.416
bone maturation GO:0070977 13 0.395
ossification GO:0001503 216 0.383
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.376
ossification involved in bone maturation GO:0043931 12 0.350
canonical wnt signaling pathway GO:0060070 130 0.336
developmental growth involved in morphogenesis GO:0060560 138 0.328
developmental maturation GO:0021700 193 0.319
regulation of cellular amine metabolic process GO:0033238 20 0.310
embryonic limb morphogenesis GO:0030326 126 0.307
ras protein signal transduction GO:0007265 77 0.303
embryonic skeletal system development GO:0048706 120 0.298
positive regulation of immature t cell proliferation GO:0033091 4 0.297
regionalization GO:0003002 337 0.297
appendage morphogenesis GO:0035107 149 0.295
replacement ossification GO:0036075 26 0.291
angiogenesis GO:0001525 201 0.279
nucleobase containing small molecule metabolic process GO:0055086 352 0.273
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.271
diencephalon development GO:0021536 63 0.265
purine containing compound metabolic process GO:0072521 311 0.261
hair follicle development GO:0001942 85 0.260
cellular lipid metabolic process GO:0044255 323 0.258
left lung development GO:0060459 4 0.256
dorsal ventral axon guidance GO:0033563 3 0.255
epithelial tube morphogenesis GO:0060562 303 0.249
regulation of mapk cascade GO:0043408 248 0.246
endochondral bone morphogenesis GO:0060350 50 0.244
odontogenesis of dentin containing tooth GO:0042475 66 0.243
muscle cell differentiation GO:0042692 261 0.240
stem cell development GO:0048864 219 0.235
organ maturation GO:0048799 17 0.222
deltoid tuberosity development GO:0035993 3 0.215
anatomical structure maturation GO:0071695 49 0.206
leukocyte differentiation GO:0002521 342 0.204
organonitrogen compound biosynthetic process GO:1901566 192 0.201
bone morphogenesis GO:0060349 78 0.199
cognition GO:0050890 149 0.196
cellular macromolecule catabolic process GO:0044265 206 0.196
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.190
cellular amine metabolic process GO:0044106 44 0.188
neural tube closure GO:0001843 90 0.186
regulation of nucleotide metabolic process GO:0006140 169 0.181
myotube differentiation GO:0014902 105 0.180
cellular nitrogen compound catabolic process GO:0044270 280 0.178
primary neural tube formation GO:0014020 95 0.176
tube lumen cavitation GO:0060605 5 0.173
telencephalon development GO:0021537 186 0.171
chondrocyte differentiation GO:0002062 72 0.171
embryonic appendage morphogenesis GO:0035113 126 0.171
peptidyl amino acid modification GO:0018193 336 0.171
neural tube development GO:0021915 160 0.169
regulation of cell motility GO:2000145 236 0.168
negative regulation of wnt signaling pathway GO:0030178 73 0.168
organic cyclic compound catabolic process GO:1901361 295 0.167
striated muscle tissue development GO:0014706 293 0.166
extraocular skeletal muscle development GO:0002074 2 0.163
nitrogen compound transport GO:0071705 271 0.163
macromolecule catabolic process GO:0009057 281 0.163
regulation of hydrolase activity GO:0051336 246 0.162
nucleoside metabolic process GO:0009116 246 0.161
glycerolipid metabolic process GO:0046486 122 0.159
protein catabolic process GO:0030163 221 0.158
glycoprotein metabolic process GO:0009100 116 0.157
negative regulation of dna templated transcription elongation GO:0032785 6 0.156
blood vessel morphogenesis GO:0048514 285 0.155
guanosine containing compound catabolic process GO:1901069 144 0.155
nucleoside phosphate metabolic process GO:0006753 338 0.154
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.153
regulation of wnt signaling pathway GO:0030111 123 0.151
nucleoside catabolic process GO:0009164 206 0.148
rho protein signal transduction GO:0007266 32 0.148
purine ribonucleoside metabolic process GO:0046128 241 0.146
forebrain development GO:0030900 302 0.145
positive regulation of cell activation GO:0050867 158 0.144
axon guidance GO:0007411 141 0.143
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.143
anatomical structure homeostasis GO:0060249 145 0.143
regulation of cellular ketone metabolic process GO:0010565 66 0.142
sensory organ morphogenesis GO:0090596 242 0.141
neuron projection extension GO:1990138 64 0.141
forebrain generation of neurons GO:0021872 63 0.141
cardiac muscle tissue morphogenesis GO:0055008 44 0.140
cellular ketone metabolic process GO:0042180 84 0.139
response to nutrient levels GO:0031667 109 0.138
male gamete generation GO:0048232 285 0.137
morphogenesis of embryonic epithelium GO:0016331 159 0.137
skeletal muscle fiber development GO:0048741 58 0.137
protein modification by small protein conjugation GO:0032446 187 0.135
fat cell differentiation GO:0045444 160 0.135
purine nucleoside triphosphate catabolic process GO:0009146 203 0.135
positive regulation of nucleoside metabolic process GO:0045979 91 0.133
negative regulation of cell migration GO:0030336 59 0.133
ribonucleoside metabolic process GO:0009119 245 0.132
multicellular organismal homeostasis GO:0048871 164 0.132
glycosyl compound catabolic process GO:1901658 206 0.130
lipid transport GO:0006869 98 0.129
guanosine containing compound metabolic process GO:1901068 144 0.127
endodermal digestive tract morphogenesis GO:0061031 4 0.126
chondrocyte development GO:0002063 24 0.123
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.123
regulation of nucleoside metabolic process GO:0009118 130 0.123
ventricular zone neuroblast division GO:0021847 3 0.121
ameboidal type cell migration GO:0001667 128 0.121
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.121
muscle cell development GO:0055001 133 0.120
branchiomeric skeletal muscle development GO:0014707 3 0.118
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.118
purine ribonucleotide catabolic process GO:0009154 208 0.117
positive regulation of growth GO:0045927 104 0.117
morphogenesis of a branching structure GO:0001763 203 0.114
regulation of steroid biosynthetic process GO:0050810 26 0.113
prostate gland morphogenetic growth GO:0060737 4 0.112
oocyte axis specification GO:0007309 2 0.112
response to metal ion GO:0010038 47 0.111
establishment or maintenance of cell polarity GO:0007163 86 0.111
cellular carbohydrate metabolic process GO:0044262 119 0.110
sensory perception GO:0007600 245 0.109
embryonic organ morphogenesis GO:0048562 276 0.109
nucleoside triphosphate metabolic process GO:0009141 230 0.109
small gtpase mediated signal transduction GO:0007264 97 0.108
gtp catabolic process GO:0006184 143 0.108
motor neuron migration GO:0097475 4 0.107
embryonic epithelial tube formation GO:0001838 130 0.107
learning or memory GO:0007611 148 0.106
lipid biosynthetic process GO:0008610 179 0.105
catecholamine uptake GO:0090493 4 0.105
cell fate commitment GO:0045165 210 0.103
closure of optic fissure GO:0061386 2 0.102
synaptic vesicle localization GO:0097479 59 0.102
gonad morphogenesis GO:0035262 1 0.102
regulation of cellular amino acid metabolic process GO:0006521 5 0.101
regulation of establishment of protein localization GO:0070201 181 0.101
steroid metabolic process GO:0008202 119 0.101
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.100
cellular protein complex assembly GO:0043623 116 0.100
head morphogenesis GO:0060323 34 0.098
muscle tissue development GO:0060537 308 0.098
cell proliferation in external granule layer GO:0021924 10 0.097
regulation of body fluid levels GO:0050878 162 0.097
positive regulation of peptide secretion GO:0002793 33 0.097
cell proliferation in hindbrain GO:0021534 10 0.097
t cell proliferation GO:0042098 120 0.096
regulation of protein catabolic process GO:0042176 108 0.095
regulation of lymphocyte proliferation GO:0050670 117 0.095
regulation of purine nucleotide catabolic process GO:0033121 122 0.095
regulation of axon extension GO:0030516 43 0.094
positive regulation of cell projection organization GO:0031346 95 0.092
ribonucleoside triphosphate catabolic process GO:0009203 199 0.092
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 2 0.091
anterior commissure morphogenesis GO:0021960 6 0.091
cation homeostasis GO:0055080 212 0.091
smoothened signaling pathway GO:0007224 105 0.091
nucleoside phosphate catabolic process GO:1901292 222 0.091
striated muscle cell development GO:0055002 125 0.091
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.091
negative regulation of cellular protein metabolic process GO:0032269 247 0.090
alcohol metabolic process GO:0006066 116 0.090
muscle fiber development GO:0048747 76 0.089
developmental cell growth GO:0048588 84 0.089
regulation of cytokine production GO:0001817 266 0.089
ribonucleoside catabolic process GO:0042454 206 0.088
positive regulation of hormone secretion GO:0046887 38 0.088
heart morphogenesis GO:0003007 178 0.087
salivary gland morphogenesis GO:0007435 33 0.086
spinal cord development GO:0021510 81 0.086
regulation of protein kinase activity GO:0045859 232 0.086
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.086
positive regulation of mapk cascade GO:0043410 170 0.084
glycosyl compound metabolic process GO:1901657 246 0.084
chondroblast differentiation GO:0060591 2 0.084
left lung morphogenesis GO:0060460 3 0.083
hormone secretion GO:0046879 128 0.083
purine ribonucleotide metabolic process GO:0009150 290 0.082
prostate epithelial cord elongation GO:0060523 3 0.082
posttranscriptional regulation of gene expression GO:0010608 155 0.082
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.082
erythrocyte differentiation GO:0030218 88 0.082
ribonucleotide catabolic process GO:0009261 208 0.081
cellular amino acid metabolic process GO:0006520 103 0.081
ribonucleotide metabolic process GO:0009259 291 0.080
embryonic skeletal system morphogenesis GO:0048704 91 0.078
positive regulation of gtp catabolic process GO:0033126 85 0.078
single organism cell adhesion GO:0098602 156 0.078
regulation of ossification GO:0030278 112 0.078
response to organonitrogen compound GO:0010243 246 0.077
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.077
regulation of cellular catabolic process GO:0031329 242 0.077
stem cell differentiation GO:0048863 268 0.076
carbohydrate derivative catabolic process GO:1901136 231 0.076
response to molecule of bacterial origin GO:0002237 143 0.076
purine nucleoside metabolic process GO:0042278 241 0.076
cytokine production GO:0001816 319 0.074
positive regulation of ossification GO:0045778 47 0.074
digestive tract development GO:0048565 190 0.074
regulation of hormone secretion GO:0046883 88 0.074
positive regulation of gtpase activity GO:0043547 85 0.073
epithelial cell morphogenesis GO:0003382 41 0.073
renal tubule development GO:0061326 87 0.072
germ cell development GO:0007281 185 0.072
central nervous system neuron differentiation GO:0021953 162 0.072
protein ubiquitination GO:0016567 171 0.072
regulation of cell migration GO:0030334 219 0.072
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.072
cell adhesion GO:0007155 329 0.071
regulation of lipid biosynthetic process GO:0046890 54 0.071
organophosphate catabolic process GO:0046434 232 0.071
positive regulation of hydrolase activity GO:0051345 148 0.071
respiratory tube development GO:0030323 167 0.071
response to organic cyclic compound GO:0014070 198 0.070
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
catecholamine secretion GO:0050432 15 0.070
regulation of stem cell proliferation GO:0072091 78 0.070
palate development GO:0060021 76 0.070
myoblast differentiation GO:0045445 52 0.069
positive regulation of cell motility GO:2000147 116 0.069
formation of radial glial scaffolds GO:0021943 4 0.069
positive regulation of lymphocyte proliferation GO:0050671 70 0.068
response to acid chemical GO:0001101 111 0.068
organonitrogen compound catabolic process GO:1901565 264 0.068
purine nucleotide catabolic process GO:0006195 211 0.067
purine ribonucleoside catabolic process GO:0046130 205 0.067
regulation of leukocyte proliferation GO:0070663 121 0.067
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.067
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.067
positive regulation of cellular amine metabolic process GO:0033240 5 0.066
negative regulation of protein modification process GO:0031400 163 0.066
positive regulation of programmed cell death GO:0043068 218 0.066
mapk cascade GO:0000165 281 0.066
protein processing GO:0016485 163 0.066
fertilization GO:0009566 127 0.066
mammary gland bud morphogenesis GO:0060648 4 0.065
regulation of ras protein signal transduction GO:0046578 114 0.065
nucleotide metabolic process GO:0009117 332 0.064
regulation of fat cell differentiation GO:0045598 81 0.064
mammary gland duct morphogenesis GO:0060603 38 0.064
t cell activation GO:0042110 289 0.063
alpha beta t cell differentiation GO:0046632 69 0.062
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.062
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.062
regulation of cell activation GO:0050865 289 0.062
g protein coupled receptor signaling pathway GO:0007186 243 0.062
proteasomal protein catabolic process GO:0010498 98 0.062
intracellular protein transport GO:0006886 204 0.062
protein import GO:0017038 101 0.061
regulation of embryonic development GO:0045995 71 0.061
nucleoside triphosphate catabolic process GO:0009143 205 0.060
negative regulation of cholesterol transport GO:0032375 4 0.060
purine nucleoside catabolic process GO:0006152 205 0.059
ribose phosphate metabolic process GO:0019693 291 0.058
myeloid cell differentiation GO:0030099 233 0.058
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.058
aromatic compound catabolic process GO:0019439 286 0.058
positive regulation of protein phosphorylation GO:0001934 242 0.058
salivary gland cavitation GO:0060662 5 0.058
muscle contraction GO:0006936 101 0.057
regulation of gtp catabolic process GO:0033124 113 0.057
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.056
forebrain neuron differentiation GO:0021879 52 0.056
negative regulation of cell motility GO:2000146 61 0.056
negative regulation of protein maturation GO:1903318 79 0.056
regulation of apoptotic signaling pathway GO:2001233 197 0.056
regulation of smoothened signaling pathway GO:0008589 58 0.055
establishment of vesicle localization GO:0051650 81 0.055
positive regulation of cellular catabolic process GO:0031331 148 0.054
regulation of neuron projection development GO:0010975 169 0.054
muscle tissue morphogenesis GO:0060415 53 0.054
ear development GO:0043583 200 0.054
mesenchymal cell differentiation GO:0048762 107 0.053
spinal cord motor neuron migration GO:0097476 4 0.053
branching involved in salivary gland morphogenesis GO:0060445 26 0.053
peptidyl tyrosine modification GO:0018212 145 0.053
molting cycle GO:0042303 90 0.053
regulation of stem cell differentiation GO:2000736 50 0.053
protein localization to membrane GO:0072657 108 0.052
regulation of protein processing GO:0070613 96 0.052
negative regulation of sterol transport GO:0032372 4 0.052
regulation of secretion by cell GO:1903530 249 0.052
endocrine system development GO:0035270 98 0.052
amine metabolic process GO:0009308 45 0.052
establishment of organelle localization GO:0051656 122 0.052
cellular ion homeostasis GO:0006873 165 0.052
generation of precursor metabolites and energy GO:0006091 103 0.052
regulation of synapse structural plasticity GO:0051823 4 0.052
positive regulation of catecholamine uptake involved in synaptic transmission GO:0051944 2 0.052
regulation of organ morphogenesis GO:2000027 144 0.052
prostate gland morphogenesis GO:0060512 32 0.052
development of primary sexual characteristics GO:0045137 143 0.051
purine nucleotide metabolic process GO:0006163 302 0.051
organelle localization GO:0051640 179 0.051
vesicle localization GO:0051648 86 0.051
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.051
positive regulation of growth hormone secretion GO:0060124 3 0.051
regulation of lipid metabolic process GO:0019216 118 0.051
regulation of stem cell division GO:2000035 4 0.051
dephosphorylation GO:0016311 129 0.051
vagus nerve development GO:0021564 3 0.050
negative regulation of proteolysis GO:0045861 74 0.050
regulation of purine nucleotide metabolic process GO:1900542 169 0.050
positive regulation of apoptotic process GO:0043065 217 0.049
negative regulation of cell proliferation GO:0008285 296 0.049
oocyte construction GO:0007308 2 0.049
modification dependent protein catabolic process GO:0019941 133 0.048
positive regulation of leukocyte proliferation GO:0070665 73 0.048
cellular response to growth factor stimulus GO:0071363 197 0.048
mammary placode formation GO:0060596 4 0.048
negative regulation of protein metabolic process GO:0051248 282 0.048
regulation of t cell proliferation GO:0042129 92 0.048
camp metabolic process GO:0046058 40 0.048
spermatid development GO:0007286 108 0.048
endocytosis GO:0006897 168 0.047
central nervous system morphogenesis GO:0021551 2 0.047
apoptotic signaling pathway GO:0097190 306 0.047
neuron projection guidance GO:0097485 141 0.047
positive regulation of wnt signaling pathway GO:0030177 45 0.047
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
cerebral cortex neuron differentiation GO:0021895 19 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.046
protein localization to nucleus GO:0034504 121 0.046
monocarboxylic acid metabolic process GO:0032787 191 0.046
positive regulation of protein modification process GO:0031401 299 0.046
neural precursor cell proliferation GO:0061351 121 0.046
wound healing GO:0042060 157 0.046
gland development GO:0048732 330 0.045
positive regulation of stem cell proliferation GO:2000648 59 0.045
metal ion homeostasis GO:0055065 189 0.045
organic anion transport GO:0015711 137 0.045
protein maturation GO:0051604 176 0.045
embryonic digit morphogenesis GO:0042733 56 0.045
synaptic transmission GO:0007268 329 0.045
multi multicellular organism process GO:0044706 109 0.044
bone resorption GO:0045453 38 0.044
regulation of myoblast differentiation GO:0045661 29 0.044
positive regulation of defense response GO:0031349 124 0.044
regulation of catecholamine secretion GO:0050433 12 0.044
peptide secretion GO:0002790 114 0.044
cartilage development GO:0051216 140 0.044
regulation of rho protein signal transduction GO:0035023 71 0.044
tube closure GO:0060606 91 0.043
insulin secretion GO:0030073 89 0.043
response to inactivity GO:0014854 4 0.043
morphogenesis of a polarized epithelium GO:0001738 37 0.043
organ growth GO:0035265 117 0.043
glial cell differentiation GO:0010001 131 0.043
regulation of intracellular transport GO:0032386 159 0.043
peptidyl tyrosine phosphorylation GO:0018108 143 0.043
maintenance of apical basal cell polarity GO:0035090 3 0.043
negative regulation of lyase activity GO:0051350 1 0.043
negative regulation of immature t cell proliferation GO:0033087 3 0.043
leukocyte proliferation GO:0070661 172 0.042
extracellular structure organization GO:0043062 148 0.042
response to peptide GO:1901652 136 0.042
nuclear transport GO:0051169 139 0.042
negative regulation of molecular function GO:0044092 258 0.042
tube formation GO:0035148 140 0.042
skin development GO:0043588 220 0.042
regulation of cellular response to growth factor stimulus GO:0090287 82 0.041
bone mineralization GO:0030282 54 0.041
protein import into nucleus GO:0006606 95 0.041
endodermal cell fate determination GO:0007493 2 0.041
cerebral cortex development GO:0021987 86 0.041
regulation of protein transport GO:0051223 163 0.041
negative regulation of axon extension GO:0030517 19 0.041
cardiac septum morphogenesis GO:0060411 46 0.041
regulation of cell proliferation in bone marrow GO:0071863 2 0.041
response to extracellular stimulus GO:0009991 127 0.041
oxidation reduction process GO:0055114 342 0.041
renal vesicle induction GO:0072034 3 0.040
extracellular matrix organization GO:0030198 147 0.040
mammary gland epithelium development GO:0061180 65 0.040
regulation of dopamine uptake involved in synaptic transmission GO:0051584 2 0.040
response to transforming growth factor beta GO:0071559 88 0.040
regulation of secretion GO:0051046 274 0.040
positive regulation of secretion GO:0051047 130 0.040
connective tissue development GO:0061448 179 0.040
regulation of cell size GO:0008361 72 0.040
regulation of mesenchymal cell proliferation GO:0010464 37 0.039
purine containing compound catabolic process GO:0072523 213 0.039
retina morphogenesis in camera type eye GO:0060042 45 0.039
negative regulation of cellular catabolic process GO:0031330 47 0.039
gliogenesis GO:0042063 141 0.039
hair cycle GO:0042633 90 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
negative regulation of cell development GO:0010721 169 0.039
striated muscle contraction GO:0006941 45 0.038
neutral lipid metabolic process GO:0006638 57 0.038
renal system development GO:0072001 225 0.038
cellular protein catabolic process GO:0044257 155 0.038
cellular chemical homeostasis GO:0055082 215 0.038
regulation of peptidase activity GO:0052547 96 0.038
cellular calcium ion homeostasis GO:0006874 119 0.038
regulation of ras gtpase activity GO:0032318 88 0.038
regulation of inflammatory response GO:0050727 147 0.038
lipid localization GO:0010876 126 0.037
spermatid differentiation GO:0048515 115 0.037
cell growth GO:0016049 130 0.037
axis elongation involved in somitogenesis GO:0090245 4 0.037
establishment of synaptic vesicle localization GO:0097480 57 0.037
thermosensory behavior GO:0040040 1 0.037
positive regulation of renal sodium excretion GO:0035815 2 0.037
eye pigmentation GO:0048069 3 0.036
b cell activation GO:0042113 161 0.036
negative regulation of leukocyte differentiation GO:1902106 51 0.036
respiratory system development GO:0060541 190 0.036
neural tube formation GO:0001841 108 0.036
positive regulation of steroid biosynthetic process GO:0010893 4 0.036
nucleotide catabolic process GO:0009166 217 0.036
positive regulation of secretion by cell GO:1903532 114 0.036
regulation of leukocyte mediated immunity GO:0002703 104 0.036
primary prostatic bud elongation GO:0060516 2 0.036
determination of heart left right asymmetry GO:0061371 48 0.036
protein targeting GO:0006605 143 0.036
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.035
regulation of voltage gated calcium channel activity GO:1901385 4 0.035
carbohydrate metabolic process GO:0005975 230 0.035
positive regulation of neural precursor cell proliferation GO:2000179 42 0.035
negative regulation of immune system process GO:0002683 209 0.035
cellular response to lithium ion GO:0071285 10 0.035
regulation of nucleocytoplasmic transport GO:0046822 73 0.035
positive regulation of insulin secretion GO:0032024 26 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.035
inflammatory response GO:0006954 244 0.035
positive regulation of nucleotide metabolic process GO:0045981 114 0.035
cellular polysaccharide metabolic process GO:0044264 38 0.034
response to iron ion GO:0010039 4 0.034
myoblast proliferation GO:0051450 11 0.034
regulation of peptide secretion GO:0002791 77 0.034
branching morphogenesis of an epithelial tube GO:0048754 159 0.034
pancreas development GO:0031016 57 0.034
chondrocyte hypertrophy GO:0003415 4 0.034
stem cell maintenance GO:0019827 130 0.034
peptide transport GO:0015833 133 0.034
establishment of tissue polarity GO:0007164 28 0.034
pulmonary myocardium development GO:0003350 3 0.034
mesenchyme development GO:0060485 152 0.034
regulation of glial cell differentiation GO:0045685 41 0.034
olfactory lobe development GO:0021988 32 0.033
neuroblast proliferation GO:0007405 49 0.033
cardiocyte differentiation GO:0035051 87 0.033
regulation of hormone levels GO:0010817 211 0.033
positive regulation of intracellular transport GO:0032388 70 0.033
determination of left right symmetry GO:0007368 80 0.033
granulocyte colony stimulating factor production GO:0071611 1 0.033
regulation of protein maturation GO:1903317 96 0.033
response to amino acid GO:0043200 37 0.033
lateral motor column neuron migration GO:0097477 3 0.033
pallium development GO:0021543 120 0.033
small molecule biosynthetic process GO:0044283 132 0.033
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.033
heart process GO:0003015 94 0.033
cardiac septum development GO:0003279 59 0.033
pituitary gland development GO:0021983 38 0.033
neural crest cell migration GO:0001755 32 0.033
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.033
cellular response to peptide hormone stimulus GO:0071375 92 0.033
positive regulation of transferase activity GO:0051347 167 0.033
regulation of ion transport GO:0043269 215 0.033
tissue homeostasis GO:0001894 115 0.033
cellular response to organonitrogen compound GO:0071417 145 0.033
epidermis development GO:0008544 187 0.032
embryonic eye morphogenesis GO:0048048 29 0.032
cardiac ventricle development GO:0003231 83 0.032
engulfment of apoptotic cell GO:0043652 3 0.032
type b pancreatic cell proliferation GO:0044342 10 0.032
cell migration involved in gastrulation GO:0042074 13 0.032
regulation of proteolysis GO:0030162 164 0.032
muscle system process GO:0003012 141 0.032
skeletal muscle organ development GO:0060538 163 0.032
ubiquitin dependent protein catabolic process GO:0006511 129 0.032
mesodermal cell migration GO:0008078 4 0.032
dopamine uptake involved in synaptic transmission GO:0051583 4 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.032
bone remodeling GO:0046849 53 0.032
negative regulation of cell cycle GO:0045786 123 0.032
regulation of muscle tissue development GO:1901861 97 0.032
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.031
positive regulation of hh target transcription factor activity GO:0007228 3 0.031
regulation of response to wounding GO:1903034 189 0.031
cellular homeostasis GO:0019725 240 0.031

Smpd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.461
musculoskeletal system disease DOID:17 0 0.461
connective tissue disease DOID:65 0 0.422
bone development disease DOID:0080006 0 0.122
bone disease DOID:0080001 0 0.122
osteochondrodysplasia DOID:2256 0 0.067