Mus musculus

0 known processes

Fxr2

fragile X mental retardation, autosomal homolog 2

(Aliases: Fxr2h)

Fxr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 187 0.202
modification dependent macromolecule catabolic process GO:0043632 133 0.186
oocyte axis specification GO:0007309 2 0.183
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.167
protein ubiquitination GO:0016567 171 0.163
cellular macromolecule catabolic process GO:0044265 206 0.144
ubiquitin dependent protein catabolic process GO:0006511 129 0.141
intracellular mrna localization GO:0008298 4 0.139
cellular protein catabolic process GO:0044257 155 0.120
modification dependent protein catabolic process GO:0019941 133 0.112
protein catabolic process GO:0030163 221 0.108
macromolecule catabolic process GO:0009057 281 0.100
intracellular protein transport GO:0006886 204 0.087
protein modification by small protein conjugation or removal GO:0070647 207 0.084
positive regulation of protein phosphorylation GO:0001934 242 0.083
mitotic cell cycle GO:0000278 195 0.077
Fly
regulation of protein kinase activity GO:0045859 232 0.076
male gamete generation GO:0048232 285 0.075
Fly
rna splicing GO:0008380 54 0.075
multicellular organism growth GO:0035264 161 0.075
mapk cascade GO:0000165 281 0.073
regionalization GO:0003002 337 0.072
Fly
segmentation GO:0035282 93 0.071
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.069
dna metabolic process GO:0006259 303 0.068
Fly
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.068
carbohydrate metabolic process GO:0005975 230 0.065
pole plasm assembly GO:0007315 2 0.065
covalent chromatin modification GO:0016569 163 0.064
response to organonitrogen compound GO:0010243 246 0.062
Fly
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.061
nuclear transport GO:0051169 139 0.061
synaptic transmission GO:0007268 329 0.061
Fly
regulation of mapk cascade GO:0043408 248 0.060
development of primary sexual characteristics GO:0045137 143 0.060
negative regulation of protein metabolic process GO:0051248 282 0.054
Mouse Fly
protein localization to organelle GO:0033365 185 0.054
proteasomal protein catabolic process GO:0010498 98 0.052
spermatogenesis GO:0007283 284 0.051
Fly
regulation of cellular catabolic process GO:0031329 242 0.047
mitotic cell cycle process GO:1903047 159 0.046
locomotory behavior GO:0007626 195 0.043
Fly
regulation of cell cycle GO:0051726 281 0.043
Fly
response to reactive oxygen species GO:0000302 56 0.043
regulation of cellular response to stress GO:0080135 159 0.042
response to oxidative stress GO:0006979 123 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
Mouse Fly
chromatin modification GO:0016568 187 0.040
Fly
regulation of stress activated mapk cascade GO:0032872 69 0.040
transmembrane transport GO:0055085 412 0.039
negative regulation of phosphate metabolic process GO:0045936 184 0.039
microtubule based process GO:0007017 236 0.039
Fly
dephosphorylation GO:0016311 129 0.039
stem cell differentiation GO:0048863 268 0.038
nucleotide catabolic process GO:0009166 217 0.038
establishment of protein localization to organelle GO:0072594 118 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
cytoplasmic transport GO:0016482 234 0.037
cellular carbohydrate metabolic process GO:0044262 119 0.037
cellular response to oxidative stress GO:0034599 76 0.036
monosaccharide metabolic process GO:0005996 106 0.036
rna processing GO:0006396 105 0.036
negative regulation of protein modification process GO:0031400 163 0.036
establishment or maintenance of cell polarity GO:0007163 86 0.035
positive regulation of protein kinase activity GO:0045860 144 0.034
ossification GO:0001503 216 0.034
regulation of protein serine threonine kinase activity GO:0071900 157 0.034
regulation of rna splicing GO:0043484 37 0.033
rna localization GO:0006403 23 0.033
Fly
jnk cascade GO:0007254 72 0.033
skeletal system development GO:0001501 356 0.032
positive regulation of cellular catabolic process GO:0031331 148 0.032
retrograde transport endosome to golgi GO:0042147 2 0.032
methylation GO:0032259 134 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
stem cell development GO:0048864 219 0.032
cell maturation GO:0048469 127 0.031
Fly
aromatic compound catabolic process GO:0019439 286 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
fatty acid transmembrane transport GO:1902001 1 0.031
sensory organ morphogenesis GO:0090596 242 0.030
response to light stimulus GO:0009416 135 0.030
cellular ketone metabolic process GO:0042180 84 0.030
autophagy GO:0006914 45 0.030
regulation of kinase activity GO:0043549 249 0.029
regulation of mrna metabolic process GO:1903311 43 0.029
stress activated mapk cascade GO:0051403 80 0.029
cellular homeostasis GO:0019725 240 0.029
establishment of organelle localization GO:0051656 122 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
anion transport GO:0006820 177 0.029
cell division GO:0051301 120 0.029
membrane organization GO:0061024 245 0.028
germ cell development GO:0007281 185 0.028
Fly
nuclear division GO:0000280 158 0.028
organelle localization GO:0051640 179 0.028
cellular lipid metabolic process GO:0044255 323 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
negative regulation of protein phosphorylation GO:0001933 126 0.028
vacuole organization GO:0007033 38 0.028
adult behavior GO:0030534 135 0.027
regulation of neuron death GO:1901214 134 0.027
nucleocytoplasmic transport GO:0006913 139 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
protein targeting GO:0006605 143 0.026
oogenesis GO:0048477 56 0.026
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
oocyte anterior posterior axis specification GO:0007314 2 0.025
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
bone development GO:0060348 120 0.025
cation transport GO:0006812 399 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.025
protein polyubiquitination GO:0000209 33 0.024
peptidyl amino acid modification GO:0018193 336 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
male sex differentiation GO:0046661 109 0.024
stress activated protein kinase signaling cascade GO:0031098 81 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
Fly
protein localization to membrane GO:0072657 108 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
regulation of protein maturation GO:1903317 96 0.024
activation of mapk activity GO:0000187 59 0.024
respiratory system development GO:0060541 190 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
glucose homeostasis GO:0042593 128 0.023
negative regulation of molecular function GO:0044092 258 0.023
lipid transport GO:0006869 98 0.023
regulation of cell cycle process GO:0010564 160 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
Fly
lymphocyte differentiation GO:0030098 242 0.023
positive regulation of protein modification process GO:0031401 299 0.023
regulation of jnk cascade GO:0046328 62 0.022
histone modification GO:0016570 159 0.022
maternal determination of anterior posterior axis embryo GO:0008358 2 0.022
regulation of transferase activity GO:0051338 263 0.022
rna catabolic process GO:0006401 29 0.022
purine containing compound catabolic process GO:0072523 213 0.022
regulation of secretion GO:0051046 274 0.021
regulation of neuron differentiation GO:0045664 281 0.021
Fly
positive regulation of nucleoside metabolic process GO:0045979 91 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
positive regulation of cell death GO:0010942 224 0.021
leukocyte differentiation GO:0002521 342 0.021
sensory system development GO:0048880 3 0.021
mrna metabolic process GO:0016071 84 0.021
ear development GO:0043583 200 0.020
chromatin organization GO:0006325 206 0.020
Fly
cell growth GO:0016049 130 0.020
cellular amine metabolic process GO:0044106 44 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
Fly
response to radiation GO:0009314 165 0.020
lateral line system development GO:0048925 1 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
response to heat GO:0009408 27 0.020
positive regulation of transferase activity GO:0051347 167 0.020
cellular response to growth factor stimulus GO:0071363 197 0.019
exocytosis GO:0006887 121 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
regulation of jak stat cascade GO:0046425 34 0.019
protein oligomerization GO:0051259 67 0.019
immune effector process GO:0002252 321 0.019
regulation of proteolysis GO:0030162 164 0.019
mrna processing GO:0006397 63 0.019
response to pain GO:0048265 26 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of system process GO:0044057 200 0.018
Fly
multi multicellular organism process GO:0044706 109 0.018
Fly
neuron death GO:0070997 154 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
positive regulation of growth GO:0045927 104 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
respiratory tube development GO:0030323 167 0.018
response to growth factor GO:0070848 198 0.018
protein localization to nucleus GO:0034504 121 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
homeostasis of number of cells GO:0048872 210 0.018
translation GO:0006412 93 0.018
Mouse Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.018
striated muscle tissue development GO:0014706 293 0.018
digestive system development GO:0055123 200 0.017
single organism nuclear import GO:1902593 95 0.017
meiosis i GO:0007127 60 0.017
cellular amino acid metabolic process GO:0006520 103 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
connective tissue development GO:0061448 179 0.017
apoptotic signaling pathway GO:0097190 306 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
axonogenesis GO:0007409 274 0.017
Fly
neuron apoptotic process GO:0051402 142 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of protein catabolic process GO:0042176 108 0.017
cell type specific apoptotic process GO:0097285 268 0.017
macroautophagy GO:0016236 21 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regulation of cell adhesion GO:0030155 154 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
oocyte construction GO:0007308 2 0.016
Fly
negative regulation of neuron death GO:1901215 98 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
spermatid development GO:0007286 108 0.016
Fly
negative regulation of cell cycle GO:0045786 123 0.016
regulation of peptide secretion GO:0002791 77 0.016
gland development GO:0048732 330 0.016
glycerolipid metabolic process GO:0046486 122 0.016
regulation of cellular protein catabolic process GO:1903362 61 0.016
regulation of secretion by cell GO:1903530 249 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
regulation of cell motility GO:2000145 236 0.016
cell junction organization GO:0034330 77 0.016
positive regulation of kinase activity GO:0033674 155 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
glucose metabolic process GO:0006006 92 0.016
nitrogen compound transport GO:0071705 271 0.016
Fly
regulation of multi organism process GO:0043900 111 0.016
peptidyl serine modification GO:0018209 83 0.016
regulation of binding GO:0051098 111 0.016
embryonic organ morphogenesis GO:0048562 276 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
endocytosis GO:0006897 168 0.015
lipid localization GO:0010876 126 0.015
myeloid cell homeostasis GO:0002262 114 0.015
nucleoside metabolic process GO:0009116 246 0.015
muscle tissue development GO:0060537 308 0.015
organophosphate catabolic process GO:0046434 232 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
Fly
cytokine production GO:0001816 319 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
skin development GO:0043588 220 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
Fly
positive regulation of map kinase activity GO:0043406 84 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
regulation of hormone secretion GO:0046883 88 0.015
hormone secretion GO:0046879 128 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.015
oxidation reduction process GO:0055114 342 0.015
plasma membrane long chain fatty acid transport GO:0015911 1 0.015
regulation of protein localization GO:0032880 231 0.015
regulation of map kinase activity GO:0043405 120 0.015
skeletal system morphogenesis GO:0048705 203 0.015
heterocycle catabolic process GO:0046700 280 0.015
fertilization GO:0009566 127 0.015
regulation of cytokine production GO:0001817 266 0.015
cell fate commitment GO:0045165 210 0.015
Fly
purine nucleotide catabolic process GO:0006195 211 0.015
gtp metabolic process GO:0046039 144 0.015
protein maturation GO:0051604 176 0.014
metencephalon development GO:0022037 89 0.014
gonad development GO:0008406 141 0.014
regulation of mrna processing GO:0050684 41 0.014
nucleotide metabolic process GO:0009117 332 0.014
asymmetric stem cell division GO:0098722 3 0.014
hexose biosynthetic process GO:0019319 39 0.014
wound healing GO:0042060 157 0.014
establishment of protein localization to membrane GO:0090150 54 0.014
protein methylation GO:0006479 81 0.014
lipid biosynthetic process GO:0008610 179 0.014
carbohydrate homeostasis GO:0033500 128 0.014
response to peptide hormone GO:0043434 127 0.014
Fly
positive regulation of nervous system development GO:0051962 221 0.014
Fly
ras protein signal transduction GO:0007265 77 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
regulation of translation GO:0006417 71 0.014
Mouse Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
axon cargo transport GO:0008088 33 0.014
protein import GO:0017038 101 0.013
skeletal muscle organ development GO:0060538 163 0.013
jak stat cascade GO:0007259 42 0.013
purine containing compound metabolic process GO:0072521 311 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
Mouse Fly
cellularization GO:0007349 1 0.013
Fly
regulation of proteasomal protein catabolic process GO:0061136 46 0.013
protein import into nucleus GO:0006606 95 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
establishment of vesicle localization GO:0051650 81 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
female gamete generation GO:0007292 74 0.013
Fly
ribonucleoside catabolic process GO:0042454 206 0.013
neurotransmitter transport GO:0006836 76 0.013
Fly
response to organic cyclic compound GO:0014070 198 0.013
regulation of response to wounding GO:1903034 189 0.013
organic anion transport GO:0015711 137 0.013
protein processing GO:0016485 163 0.013
protein homooligomerization GO:0051260 43 0.013
male gonad development GO:0008584 88 0.013
pharynx development GO:0060465 1 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
epidermis development GO:0008544 187 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
regulation of body fluid levels GO:0050878 162 0.013
response to peptide GO:1901652 136 0.013
Fly
macromolecule methylation GO:0043414 120 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.012
response to insulin GO:0032868 100 0.012
Fly
fatty acid metabolic process GO:0006631 121 0.012
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.012
developmental maturation GO:0021700 193 0.012
Fly
regulation of exocytosis GO:0017157 61 0.012
positive regulation of stress activated mapk cascade GO:0032874 48 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
organelle disassembly GO:1903008 2 0.012
regulation of ion transport GO:0043269 215 0.012
establishment of protein localization to vacuole GO:0072666 4 0.012
regulation of protein processing GO:0070613 96 0.012
leukocyte mediated immunity GO:0002443 174 0.012
adult locomotory behavior GO:0008344 91 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
ion transmembrane transport GO:0034220 361 0.012
microtubule sliding GO:0051012 1 0.012
regulation of organelle organization GO:0033043 289 0.012
myeloid cell differentiation GO:0030099 233 0.012
learning or memory GO:0007611 148 0.012
Fly
sensory perception GO:0007600 245 0.012
Fly
nuclear import GO:0051170 95 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
male meiosis GO:0007140 37 0.012
glucan metabolic process GO:0044042 32 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.011
positive regulation of cell development GO:0010720 237 0.011
Fly
negative regulation of growth GO:0045926 99 0.011
Fly
response to topologically incorrect protein GO:0035966 25 0.011
meiotic cell cycle GO:0051321 122 0.011
cell adhesion GO:0007155 329 0.011
regulation of hydrolase activity GO:0051336 246 0.011
acylglycerol metabolic process GO:0006639 55 0.011
dna repair GO:0006281 107 0.011
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
maintenance of location GO:0051235 89 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
regulation of cell activation GO:0050865 289 0.011
placenta development GO:0001890 140 0.011
regulation of defense response GO:0031347 233 0.011
compound eye development GO:0048749 1 0.011
innate immune response GO:0045087 157 0.011
developmental cell growth GO:0048588 84 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.011
triglyceride metabolic process GO:0006641 51 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
synaptic vesicle transport GO:0048489 57 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
negative regulation of kinase activity GO:0033673 81 0.011
camera type eye development GO:0043010 266 0.011
chemotaxis GO:0006935 247 0.011
Fly
establishment of synaptic vesicle localization GO:0097480 57 0.011
response to nutrient levels GO:0031667 109 0.011
regulation of jun kinase activity GO:0043506 40 0.011
response to inorganic substance GO:0010035 96 0.011
cellular response to peptide GO:1901653 92 0.011
Fly
neuron projection extension GO:1990138 64 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.010
sodium ion transport GO:0006814 73 0.010
extracellular matrix organization GO:0030198 147 0.010
mrna splicing via spliceosome GO:0000398 43 0.010
organelle fission GO:0048285 170 0.010
mitotic nuclear division GO:0007067 48 0.010
establishment of spindle localization GO:0051293 19 0.010
rhythmic process GO:0048511 174 0.010
Fly
embryonic placenta development GO:0001892 98 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
synapse assembly GO:0007416 56 0.010
Fly
microtubule based transport GO:0010970 50 0.010
tissue remodeling GO:0048771 102 0.010
circulatory system process GO:0003013 197 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
protein localization to endosome GO:0036010 2 0.010

Fxr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.022
central nervous system disease DOID:331 0 0.022
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013
disease of cellular proliferation DOID:14566 0 0.011
disease of metabolism DOID:0014667 0 0.011
motor neuron disease DOID:231 0 0.010
neurodegenerative disease DOID:1289 0 0.010
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010