Mus musculus

0 known processes

Pitrm1

pitrilysin metallepetidase 1

(Aliases: Ntup1,mKIAA1104,MP-1,2310012C15Rik,MP1,AA410010,PreP)

Pitrm1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.216
translation GO:0006412 93 0.112
cellular ketone metabolic process GO:0042180 84 0.068
apoptotic signaling pathway GO:0097190 306 0.054
cytoplasmic transport GO:0016482 234 0.053
amine metabolic process GO:0009308 45 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
macromolecule catabolic process GO:0009057 281 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
nucleocytoplasmic transport GO:0006913 139 0.043
organic cyclic compound catabolic process GO:1901361 295 0.037
cellular macromolecule catabolic process GO:0044265 206 0.036
regulation of membrane potential GO:0042391 192 0.036
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
cellular amine metabolic process GO:0044106 44 0.035
oxidation reduction process GO:0055114 342 0.033
protein maturation GO:0051604 176 0.033
intrinsic apoptotic signaling pathway GO:0097193 132 0.032
multicellular organismal homeostasis GO:0048871 164 0.032
transmembrane transport GO:0055085 412 0.032
anatomical structure homeostasis GO:0060249 145 0.032
dna metabolic process GO:0006259 303 0.031
heterocycle catabolic process GO:0046700 280 0.031
immune effector process GO:0002252 321 0.031
positive regulation of cell death GO:0010942 224 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
inflammatory response GO:0006954 244 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
intracellular protein transport GO:0006886 204 0.029
nitrogen compound transport GO:0071705 271 0.029
membrane organization GO:0061024 245 0.029
action potential GO:0001508 78 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
nuclear import GO:0051170 95 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
purine containing compound metabolic process GO:0072521 311 0.026
cation transport GO:0006812 399 0.026
peptidyl amino acid modification GO:0018193 336 0.026
maintenance of location GO:0051235 89 0.026
aromatic compound catabolic process GO:0019439 286 0.025
lymphocyte mediated immunity GO:0002449 139 0.025
regulation of cell activation GO:0050865 289 0.025
protein localization to nucleus GO:0034504 121 0.025
nuclear transport GO:0051169 139 0.025
multicellular organismal signaling GO:0035637 91 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
single organism nuclear import GO:1902593 95 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
nucleotide catabolic process GO:0009166 217 0.022
methylation GO:0032259 134 0.022
regulation of cell cycle GO:0051726 281 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.021
organelle fission GO:0048285 170 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
cation transmembrane transport GO:0098655 266 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
production of molecular mediator of immune response GO:0002440 103 0.021
mitotic cell cycle GO:0000278 195 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
negative regulation of molecular function GO:0044092 258 0.020
organelle localization GO:0051640 179 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
protein targeting GO:0006605 143 0.020
response to oxidative stress GO:0006979 123 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
regulation of protein transport GO:0051223 163 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
regulation of intracellular transport GO:0032386 159 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
regulation of cellular response to stress GO:0080135 159 0.019
organelle disassembly GO:1903008 2 0.019
histone modification GO:0016570 159 0.018
regulation of protein localization GO:0032880 231 0.018
b cell activation GO:0042113 161 0.018
response to organic cyclic compound GO:0014070 198 0.018
cell adhesion GO:0007155 329 0.018
regulation of translation GO:0006417 71 0.018
rna processing GO:0006396 105 0.018
regulation of cell migration GO:0030334 219 0.018
protein localization to organelle GO:0033365 185 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
regulation of protein localization to nucleus GO:1900180 60 0.018
chemotaxis GO:0006935 247 0.017
microtubule based process GO:0007017 236 0.017
nucleotide metabolic process GO:0009117 332 0.017
regulation of intracellular protein transport GO:0033157 82 0.017
positive regulation of intracellular transport GO:0032388 70 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
endocytosis GO:0006897 168 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
regulation of kinase activity GO:0043549 249 0.017
cell type specific apoptotic process GO:0097285 268 0.017
transmission of nerve impulse GO:0019226 76 0.017
cellular response to oxidative stress GO:0034599 76 0.017
tissue homeostasis GO:0001894 115 0.017
lateral inhibition GO:0046331 1 0.017
response to organonitrogen compound GO:0010243 246 0.017
protein catabolic process GO:0030163 221 0.017
positive regulation of apoptotic process GO:0043065 217 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
purine containing compound catabolic process GO:0072523 213 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
neuron apoptotic process GO:0051402 142 0.016
cellular lipid metabolic process GO:0044255 323 0.016
protein processing GO:0016485 163 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
divalent metal ion transport GO:0070838 172 0.016
adaptive immune response GO:0002250 155 0.016
cell activation involved in immune response GO:0002263 126 0.016
cellular homeostasis GO:0019725 240 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
neuronal action potential GO:0019228 54 0.016
regulation of cell motility GO:2000145 236 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
blood circulation GO:0008015 195 0.015
regulation of protein targeting GO:1903533 61 0.015
cell growth GO:0016049 130 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
cytokine production GO:0001816 319 0.015
regulation of nucleocytoplasmic transport GO:0046822 73 0.015
chromatin organization GO:0006325 206 0.015
response to growth factor GO:0070848 198 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of cell adhesion GO:0030155 154 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
endomembrane system organization GO:0010256 147 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
dna repair GO:0006281 107 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of organelle organization GO:0033043 289 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
protein import GO:0017038 101 0.014
divalent inorganic cation transport GO:0072511 178 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
nucleoside metabolic process GO:0009116 246 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
ras protein signal transduction GO:0007265 77 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
regulation of protein catabolic process GO:0042176 108 0.014
myeloid cell differentiation GO:0030099 233 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
negative regulation of protein modification process GO:0031400 163 0.014
ion transmembrane transport GO:0034220 361 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
positive regulation of protein modification process GO:0031401 299 0.014
somatic diversification of immune receptors GO:0002200 53 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
cellular protein complex assembly GO:0043623 116 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
leukocyte mediated immunity GO:0002443 174 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
regulation of neuron projection development GO:0010975 169 0.013
metal ion homeostasis GO:0055065 189 0.013
lipid localization GO:0010876 126 0.013
axonogenesis GO:0007409 274 0.013
small molecule biosynthetic process GO:0044283 132 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
response to inorganic substance GO:0010035 96 0.013
somatic cell dna recombination GO:0016444 51 0.013
nuclear division GO:0000280 158 0.013
organophosphate catabolic process GO:0046434 232 0.013
response to reactive oxygen species GO:0000302 56 0.013
leukocyte differentiation GO:0002521 342 0.013
leukocyte migration GO:0050900 124 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
nucleus organization GO:0006997 45 0.012
glycoprotein metabolic process GO:0009100 116 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
chromatin modification GO:0016568 187 0.012
gonad development GO:0008406 141 0.012
mitochondrial translation GO:0032543 4 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
regulation of inflammatory response GO:0050727 147 0.012
establishment of rna localization GO:0051236 18 0.012
establishment of organelle localization GO:0051656 122 0.012
cellular response to lipid GO:0071396 145 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
cellular amide metabolic process GO:0043603 58 0.012
regulation of hydrolase activity GO:0051336 246 0.012
cellular chemical homeostasis GO:0055082 215 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
antimicrobial peptide production GO:0002775 2 0.012
antimicrobial peptide biosynthetic process GO:0002777 2 0.012
regulation of neuron differentiation GO:0045664 281 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of protein import into nucleus GO:0042306 52 0.012
mrna metabolic process GO:0016071 84 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
metaphase plate congression GO:0051310 2 0.012
male gamete generation GO:0048232 285 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of transcription factor import into nucleus GO:0042990 24 0.012
sensory perception GO:0007600 245 0.012
immunoglobulin production GO:0002377 73 0.011
regulation of response to wounding GO:1903034 189 0.011
regulation of transferase activity GO:0051338 263 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
positive regulation of cell development GO:0010720 237 0.011
regulation of defense response GO:0031347 233 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
cation homeostasis GO:0055080 212 0.011
peptidyl lysine modification GO:0018205 77 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of protein kinase activity GO:0045859 232 0.011
germ cell development GO:0007281 185 0.011
calcium ion transport GO:0006816 159 0.011
cellular ion homeostasis GO:0006873 165 0.011
cellular response to oxygen radical GO:0071450 14 0.011
circulatory system process GO:0003013 197 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
atp metabolic process GO:0046034 75 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
innate immune response GO:0045087 157 0.011
double strand break repair GO:0006302 48 0.011
t cell activation GO:0042110 289 0.011
muscle tissue development GO:0060537 308 0.011
renal system development GO:0072001 225 0.011
response to transforming growth factor beta GO:0071559 88 0.011
protein methylation GO:0006479 81 0.011
cellular protein catabolic process GO:0044257 155 0.011
response to extracellular stimulus GO:0009991 127 0.011
protein import into nucleus GO:0006606 95 0.011
dna recombination GO:0006310 92 0.011
phospholipid metabolic process GO:0006644 87 0.011
cell fate commitment GO:0045165 210 0.010
protein localization to membrane GO:0072657 108 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
regulation of cytokine production GO:0001817 266 0.010
anion transport GO:0006820 177 0.010
neural precursor cell proliferation GO:0061351 121 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
urogenital system development GO:0001655 261 0.010
stem cell differentiation GO:0048863 268 0.010
meiotic nuclear division GO:0007126 115 0.010
forebrain development GO:0030900 302 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
meiotic cell cycle GO:0051321 122 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
positive regulation of protein localization to nucleus GO:1900182 30 0.010

Pitrm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.030
disease of anatomical entity DOID:7 0 0.030
eye and adnexa disease DOID:1492 0 0.030
nervous system disease DOID:863 0 0.030
disease of metabolism DOID:0014667 0 0.018
retinal disease DOID:5679 0 0.017
eye disease DOID:5614 0 0.017
disease of cellular proliferation DOID:14566 0 0.016
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
retinal degeneration DOID:8466 0 0.013
inherited metabolic disorder DOID:655 0 0.012