Mus musculus

0 known processes

Csprs

component of Sp100-rs

(Aliases: HSR,MGC29132,D1Lub1)

Csprs biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of defense response GO:0031347 233 0.289
innate immune response GO:0045087 157 0.265
immune response activating signal transduction GO:0002757 116 0.211
regulation of innate immune response GO:0045088 91 0.149
immune response regulating signaling pathway GO:0002764 125 0.140
positive regulation of defense response GO:0031349 124 0.131
immune effector process GO:0002252 321 0.128
response to molecule of bacterial origin GO:0002237 143 0.119
cellular response to lipopolysaccharide GO:0071222 77 0.114
activation of immune response GO:0002253 138 0.102
regulation of cell activation GO:0050865 289 0.088
positive regulation of cytokine production GO:0001819 174 0.085
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.079
cellular response to biotic stimulus GO:0071216 92 0.079
innate immune response activating signal transduction GO:0002758 50 0.078
reactive oxygen species metabolic process GO:0072593 84 0.073
toll like receptor signaling pathway GO:0002224 38 0.073
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.068
pattern recognition receptor signaling pathway GO:0002221 47 0.068
regulation of leukocyte mediated immunity GO:0002703 104 0.065
cellular amino acid metabolic process GO:0006520 103 0.065
defense response to other organism GO:0098542 197 0.063
t cell activation GO:0042110 289 0.057
negative regulation of immune system process GO:0002683 209 0.056
positive regulation of innate immune response GO:0045089 80 0.055
activation of innate immune response GO:0002218 56 0.054
response to lipopolysaccharide GO:0032496 128 0.054
negative regulation of defense response GO:0031348 77 0.053
cellular response to molecule of bacterial origin GO:0071219 83 0.053
cellular response to lipid GO:0071396 145 0.053
positive regulation of immune effector process GO:0002699 107 0.048
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.048
reactive oxygen species biosynthetic process GO:1903409 8 0.048
leukocyte mediated immunity GO:0002443 174 0.046
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.046
viral transcription GO:0019083 3 0.045
regulation of cytokine production GO:0001817 266 0.045
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.044
positive regulation of viral entry into host cell GO:0046598 3 0.043
regulation of interleukin 6 production GO:0032675 55 0.043
regulation of response to wounding GO:1903034 189 0.043
reactive nitrogen species metabolic process GO:2001057 0 0.042
regulation of inflammatory response GO:0050727 147 0.042
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.042
cytokine production GO:0001816 319 0.041
cellular response to peptidoglycan GO:0071224 4 0.041
amine metabolic process GO:0009308 45 0.041
positive regulation of cell activation GO:0050867 158 0.040
regulation of establishment of protein localization GO:0070201 181 0.039
aromatic compound catabolic process GO:0019439 286 0.038
interleukin 6 production GO:0032635 58 0.038
negative regulation of multi organism process GO:0043901 68 0.038
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
cation transport GO:0006812 399 0.037
regulation of protein transport GO:0051223 163 0.036
cellular ketone metabolic process GO:0042180 84 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
inflammatory response GO:0006954 244 0.035
regulation of protein localization GO:0032880 231 0.035
regulation of interferon gamma production GO:0032649 57 0.034
negative regulation of protein metabolic process GO:0051248 282 0.034
response to molecule of fungal origin GO:0002238 4 0.034
defense response to virus GO:0051607 68 0.034
apoptotic signaling pathway GO:0097190 306 0.034
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.034
cellular amine metabolic process GO:0044106 44 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
peptidyl amino acid modification GO:0018193 336 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
membrane organization GO:0061024 245 0.032
regulation of interferon beta production GO:0032648 13 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
multicellular organismal signaling GO:0035637 91 0.031
cell activation involved in immune response GO:0002263 126 0.030
regulation of secretion by cell GO:1903530 249 0.030
interferon beta biosynthetic process GO:0045350 4 0.030
lymphocyte proliferation GO:0046651 164 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
cell killing GO:0001906 67 0.030
positive regulation of interleukin 18 production GO:0032741 2 0.030
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.030
regulation of leukocyte proliferation GO:0070663 121 0.030
interleukin 18 production GO:0032621 4 0.029
regulation of reactive oxygen species metabolic process GO:2000377 40 0.028
toll like receptor 7 signaling pathway GO:0034154 4 0.028
regulation of interleukin 18 production GO:0032661 3 0.027
protein secretion GO:0009306 111 0.027
positive regulation of interferon gamma production GO:0032729 39 0.027
regulation of interferon beta biosynthetic process GO:0045357 4 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
regulation of natural killer cell activation GO:0032814 22 0.027
organophosphate catabolic process GO:0046434 232 0.027
regulation of kinase activity GO:0043549 249 0.026
transepithelial chloride transport GO:0030321 4 0.026
natural killer cell activation GO:0030101 44 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
regulation of secretion GO:0051046 274 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
organic cyclic compound catabolic process GO:1901361 295 0.025
regulation of membrane potential GO:0042391 192 0.025
macromolecule catabolic process GO:0009057 281 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
myeloid leukocyte activation GO:0002274 83 0.025
rho protein signal transduction GO:0007266 32 0.025
action potential GO:0001508 78 0.025
cellular macromolecule catabolic process GO:0044265 206 0.024
type i interferon production GO:0032606 29 0.024
regulation of cell killing GO:0031341 40 0.024
regulation of body fluid levels GO:0050878 162 0.024
dna metabolic process GO:0006259 303 0.024
neuronal action potential GO:0019228 54 0.024
regulation of lymphocyte mediated immunity GO:0002706 84 0.024
small gtpase mediated signal transduction GO:0007264 97 0.023
interferon gamma production GO:0032609 67 0.023
viral gene expression GO:0019080 3 0.023
cytokine biosynthetic process GO:0042089 68 0.023
leukocyte proliferation GO:0070661 172 0.023
positive regulation of secretion GO:0051047 130 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
transmission of nerve impulse GO:0019226 76 0.023
t cell extravasation GO:0072683 4 0.022
regulation of mapk cascade GO:0043408 248 0.022
tumor necrosis factor production GO:0032640 50 0.022
heterocycle catabolic process GO:0046700 280 0.022
protein catabolic process GO:0030163 221 0.022
ras protein signal transduction GO:0007265 77 0.022
regulation of cell migration GO:0030334 219 0.022
interspecies interaction between organisms GO:0044419 83 0.021
positive regulation of interferon alpha production GO:0032727 4 0.021
natural killer cell mediated immunity GO:0002228 29 0.021
sequestering of metal ion GO:0051238 19 0.021
protein ubiquitination GO:0016567 171 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
chemokine production GO:0032602 34 0.021
cytokine metabolic process GO:0042107 71 0.021
negative regulation of cytokine production GO:0001818 84 0.021
leukocyte mediated cytotoxicity GO:0001909 62 0.020
negative regulation of cell development GO:0010721 169 0.020
positive regulation of cytokine biosynthetic process GO:0042108 40 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.020
nucleotide metabolic process GO:0009117 332 0.020
nitrogen compound transport GO:0071705 271 0.020
defense response to bacterium GO:0042742 119 0.020
regulation of tumor necrosis factor production GO:0032680 49 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
cellular chemical homeostasis GO:0055082 215 0.020
divalent inorganic cation transport GO:0072511 178 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
negative regulation of immune effector process GO:0002698 55 0.020
regulation of viral transcription GO:0046782 3 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of natural killer cell mediated immunity GO:0002715 19 0.019
sequestering of calcium ion GO:0051208 18 0.019
mapk cascade GO:0000165 281 0.019
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.019
regulation of defense response to virus GO:0050688 18 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
positive regulation of actin nucleation GO:0051127 3 0.019
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.019
regulation of lymphocyte proliferation GO:0050670 117 0.018
interferon beta production GO:0032608 16 0.018
i kappab kinase nf kappab signaling GO:0007249 85 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
regulation of actin nucleation GO:0051125 4 0.018
regulation of cytokine secretion GO:0050707 61 0.018
positive regulation of protein modification process GO:0031401 299 0.018
negative regulation of viral transcription GO:0032897 3 0.017
positive regulation of viral genome replication GO:0045070 2 0.017
negative regulation of molecular function GO:0044092 258 0.017
regulation of cell cycle GO:0051726 281 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
negative regulation of interleukin 6 production GO:0032715 17 0.017
positive regulation of protein transport GO:0051222 93 0.017
detection of molecule of bacterial origin GO:0032490 2 0.017
regulation of multi organism process GO:0043900 111 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
regulation of cytokine biosynthetic process GO:0042035 59 0.017
oxidation reduction process GO:0055114 342 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
blood vessel morphogenesis GO:0048514 285 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
natural killer cell mediated cytotoxicity GO:0042267 29 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.016
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.016
ossification GO:0001503 216 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
cytokine secretion GO:0050663 72 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
cell type specific apoptotic process GO:0097285 268 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
response to host GO:0075136 3 0.015
adaptive immune response GO:0002250 155 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
purine containing compound catabolic process GO:0072523 213 0.015
cytoplasmic transport GO:0016482 234 0.015
negative regulation of nervous system development GO:0051961 156 0.015
regulation of b cell activation GO:0050864 81 0.015
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
viral process GO:0016032 41 0.015
endocytosis GO:0006897 168 0.015
cellular lipid metabolic process GO:0044255 323 0.015
response to organic cyclic compound GO:0014070 198 0.015
nucleotide catabolic process GO:0009166 217 0.015
positive regulation of response to wounding GO:1903036 66 0.015
regulation of organelle organization GO:0033043 289 0.015
ensheathment of neurons GO:0007272 76 0.015
cellular homeostasis GO:0019725 240 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
positive regulation of t cell activation GO:0050870 101 0.014
positive regulation of lymphocyte proliferation GO:0050671 70 0.014
myeloid cell differentiation GO:0030099 233 0.014
regulation of cell motility GO:2000145 236 0.014
regulation of protein kinase activity GO:0045859 232 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.014
regulation of protein secretion GO:0050708 82 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.014
antigen receptor mediated signaling pathway GO:0050851 64 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
protein processing GO:0016485 163 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
positive regulation of leukocyte mediated immunity GO:0002705 70 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
regulation of anatomical structure size GO:0090066 178 0.014
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.014
purine containing compound metabolic process GO:0072521 311 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
wound healing GO:0042060 157 0.014
response to acid chemical GO:0001101 111 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
positive regulation of interleukin 6 production GO:0032755 37 0.013
anatomical structure homeostasis GO:0060249 145 0.013
response to host immune response GO:0052572 3 0.013
regulation of chemokine production GO:0032642 30 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
carbohydrate metabolic process GO:0005975 230 0.013
regulation of actin filament based process GO:0032970 99 0.013
regulation of toll like receptor signaling pathway GO:0034121 20 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of type i interferon production GO:0032479 22 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
regulation of map kinase activity GO:0043405 120 0.013
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.013
anion transport GO:0006820 177 0.013
muscle tissue development GO:0060537 308 0.013
regulation of ion transport GO:0043269 215 0.013
positive regulation of cell death GO:0010942 224 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
regulation of t cell costimulation GO:2000523 2 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
sensory perception GO:0007600 245 0.012
regulation of transferase activity GO:0051338 263 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
negative regulation of secretion GO:0051048 61 0.012
regulation of response to biotic stimulus GO:0002831 38 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
response to organonitrogen compound GO:0010243 246 0.012
positive regulation of leukocyte proliferation GO:0070665 73 0.012
regulation of hydrolase activity GO:0051336 246 0.012
cellular ion homeostasis GO:0006873 165 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
positive regulation of cell killing GO:0031343 33 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
muscle cell differentiation GO:0042692 261 0.012
protein maturation GO:0051604 176 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
myelination GO:0042552 74 0.012
modulation by organism of defense response of other organism involved in symbiotic interaction GO:0052255 1 0.012
viral genome replication GO:0019079 17 0.012
positive regulation of type i interferon production GO:0032481 14 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
b cell activation involved in immune response GO:0002312 50 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
protein polymerization GO:0051258 57 0.012
actin filament polymerization GO:0030041 44 0.012
negative regulation of leukocyte mediated immunity GO:0002704 29 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.012
positive regulation of interferon alpha biosynthetic process GO:0045356 1 0.012
cation transmembrane transport GO:0098655 266 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
metal ion homeostasis GO:0055065 189 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070434 2 0.011
hatching GO:0035188 4 0.011
plasma membrane organization GO:0007009 90 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
nitric oxide biosynthetic process GO:0006809 25 0.011
regulation of system process GO:0044057 200 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of interleukin 1 production GO:0032652 26 0.011
regulation of b cell proliferation GO:0030888 39 0.011
modification by symbiont of host morphology or physiology GO:0044003 4 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.011
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
regulation of cellular response to stress GO:0080135 159 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
regulation of intracellular transport GO:0032386 159 0.011
regulation of immunological synapse formation GO:2000520 2 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
divalent metal ion transport GO:0070838 172 0.011
maintenance of location GO:0051235 89 0.011
forebrain development GO:0030900 302 0.011
t cell proliferation GO:0042098 120 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
actin polymerization or depolymerization GO:0008154 54 0.010
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
epidermis development GO:0008544 187 0.010
amino acid transport GO:0006865 61 0.010
microglial cell activation GO:0001774 3 0.010
cell adhesion GO:0007155 329 0.010
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
cellular protein complex assembly GO:0043623 116 0.010
positive regulation of interleukin 1 alpha production GO:0032730 4 0.010
homeostasis of number of cells GO:0048872 210 0.010
regulation of protein catabolic process GO:0042176 108 0.010
regulation of actin filament polymerization GO:0030833 38 0.010
nucleoside catabolic process GO:0009164 206 0.010
regulation of t cell extravasation GO:2000407 3 0.010
mature dendritic cell differentiation GO:0097029 3 0.010
cellular response to interferon beta GO:0035458 21 0.010
interleukin 8 production GO:0032637 4 0.010
regulation of ossification GO:0030278 112 0.010
intracellular protein transport GO:0006886 204 0.010
organism emergence from protective structure GO:0071684 4 0.010

Csprs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
disease of metabolism DOID:0014667 0 0.015
connective tissue disease DOID:65 0 0.013
immune system disease DOID:2914 0 0.013
bone disease DOID:0080001 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012