Mus musculus

36 known processes

Ephb4

Eph receptor B4

(Aliases: MDK2,Tyro11,Htk,AI042935,Myk1)

Ephb4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
kidney development GO:0001822 213 0.604
epithelial tube morphogenesis GO:0060562 303 0.582
Mouse
regulation of gtp catabolic process GO:0033124 113 0.580
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.521
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.487
Mouse
embryonic organ morphogenesis GO:0048562 276 0.470
Mouse
urogenital system development GO:0001655 261 0.450
Mouse
aromatic compound catabolic process GO:0019439 286 0.438
Mouse
gtp metabolic process GO:0046039 144 0.411
Mouse
renal system development GO:0072001 225 0.410
small gtpase mediated signal transduction GO:0007264 97 0.398
rac protein signal transduction GO:0016601 13 0.388
cellular ketone metabolic process GO:0042180 84 0.380
purine ribonucleoside metabolic process GO:0046128 241 0.332
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.327
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.327
Mouse
lung development GO:0030324 164 0.321
ribose phosphate metabolic process GO:0019693 291 0.320
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.316
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.314
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.312
Mouse
regulation of hydrolase activity GO:0051336 246 0.307
Mouse
skeletal system development GO:0001501 356 0.298
Mouse
nucleoside catabolic process GO:0009164 206 0.298
Mouse
organophosphate catabolic process GO:0046434 232 0.297
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.294
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.283
cell junction assembly GO:0034329 52 0.282
regulation of transferase activity GO:0051338 263 0.280
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.280
Mouse
amine metabolic process GO:0009308 45 0.274
ribonucleoside triphosphate catabolic process GO:0009203 199 0.267
Mouse
camera type eye development GO:0043010 266 0.261
Mouse
cellular amino acid metabolic process GO:0006520 103 0.260
purine containing compound catabolic process GO:0072523 213 0.260
Mouse
purine nucleotide metabolic process GO:0006163 302 0.258
Mouse
ras protein signal transduction GO:0007265 77 0.255
skeletal muscle organ development GO:0060538 163 0.253
guanosine containing compound metabolic process GO:1901068 144 0.247
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.247
skeletal system morphogenesis GO:0048705 203 0.239
purine nucleoside catabolic process GO:0006152 205 0.237
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.236
glycosyl compound catabolic process GO:1901658 206 0.233
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.231
Worm
organonitrogen compound catabolic process GO:1901565 264 0.228
Mouse
morphogenesis of a branching structure GO:0001763 203 0.226
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.226
Mouse
cellular amine metabolic process GO:0044106 44 0.225
purine nucleoside metabolic process GO:0042278 241 0.224
Mouse
cell adhesion GO:0007155 329 0.220
Human Mouse
epithelial tube formation GO:0072175 130 0.214
neural tube development GO:0021915 160 0.213
Mouse
developmental maturation GO:0021700 193 0.210
Mouse Worm
muscle cell differentiation GO:0042692 261 0.203
regulation of protein kinase activity GO:0045859 232 0.202
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.201
Mouse
nephron development GO:0072006 109 0.201
carbohydrate derivative catabolic process GO:1901136 231 0.189
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.184
Mouse
ossification GO:0001503 216 0.183
Mouse
lens development in camera type eye GO:0002088 62 0.183
Mouse
regulation of cell migration GO:0030334 219 0.180
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.177
Mouse
regulation of organelle organization GO:0033043 289 0.177
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.173
Mouse
cell cell junction organization GO:0045216 72 0.171
stem cell differentiation GO:0048863 268 0.171
Mouse
synaptic transmission GO:0007268 329 0.170
Mouse
heart morphogenesis GO:0003007 178 0.170
gtp catabolic process GO:0006184 143 0.167
Mouse
regulation of ras gtpase activity GO:0032318 88 0.164
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.163
Mouse
regulation of protein localization to nucleus GO:1900180 60 0.160
retinal blood vessel morphogenesis GO:0061304 3 0.154
heterocycle catabolic process GO:0046700 280 0.153
Mouse
cell junction organization GO:0034330 77 0.151
nucleotide metabolic process GO:0009117 332 0.150
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.149
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.149
regulation of protein localization GO:0032880 231 0.148
regulation of cellular catabolic process GO:0031329 242 0.148
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.142
Mouse
skin development GO:0043588 220 0.142
actin cytoskeleton organization GO:0030036 220 0.141
Mouse
striated muscle tissue development GO:0014706 293 0.141
mesenchymal cell differentiation GO:0048762 107 0.140
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.139
muscle tissue development GO:0060537 308 0.139
cognition GO:0050890 149 0.138
Mouse
regulation of muscle tissue development GO:1901861 97 0.138
regulation of apoptotic signaling pathway GO:2001233 197 0.135
embryonic epithelial tube formation GO:0001838 130 0.134
positive regulation of cellular amine metabolic process GO:0033240 5 0.134
nephron epithelium development GO:0072009 92 0.132
regulation of purine nucleotide metabolic process GO:1900542 169 0.130
Mouse
primary neural tube formation GO:0014020 95 0.129
regulation of cytoskeleton organization GO:0051493 122 0.128
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.121
Mouse
ribonucleotide metabolic process GO:0009259 291 0.119
Mouse
epithelial cell morphogenesis GO:0003382 41 0.118
regulation of cellular component biogenesis GO:0044087 181 0.118
Mouse
regulation of secretion GO:0051046 274 0.118
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.117
Mouse
intracellular protein transport GO:0006886 204 0.117
rho protein signal transduction GO:0007266 32 0.117
neuron projection guidance GO:0097485 141 0.115
Mouse Worm
chemotaxis GO:0006935 247 0.114
Mouse Worm
cell substrate adhesion GO:0031589 130 0.114
protein localization to membrane GO:0072657 108 0.112
single organism cell adhesion GO:0098602 156 0.110
Mouse
ribonucleoside catabolic process GO:0042454 206 0.108
Mouse
epidermis development GO:0008544 187 0.106
sensory perception GO:0007600 245 0.106
Mouse
kidney epithelium development GO:0072073 121 0.105
renal tubule development GO:0061326 87 0.105
peptidyl tyrosine phosphorylation GO:0018108 143 0.105
Human Mouse Worm
cartilage development GO:0051216 140 0.104
stem cell development GO:0048864 219 0.103
Mouse
cell migration involved in endocardial cushion formation GO:0003273 3 0.102
respiratory system development GO:0060541 190 0.102
regulation of cell motility GO:2000145 236 0.102
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.102
regulation of epithelial to mesenchymal transition GO:0010717 22 0.100
Mouse
tube formation GO:0035148 140 0.100
glial cell differentiation GO:0010001 131 0.099
Mouse
peptidyl amino acid modification GO:0018193 336 0.098
Human Mouse Worm
positive regulation of mapk cascade GO:0043410 170 0.097
Mouse
protein import into nucleus GO:0006606 95 0.097
cardiac chamber morphogenesis GO:0003206 93 0.096
purine ribonucleotide catabolic process GO:0009154 208 0.096
Mouse
regulation of cytokine production GO:0001817 266 0.096
wnt signaling pathway GO:0016055 188 0.095
morphogenesis of a branching epithelium GO:0061138 193 0.094
Mouse
adherens junction assembly GO:0034333 22 0.094
epithelial cell development GO:0002064 159 0.093
Mouse
regulation of cell adhesion GO:0030155 154 0.093
Mouse
nucleotide catabolic process GO:0009166 217 0.093
Mouse
apoptotic signaling pathway GO:0097190 306 0.092
muscle cell development GO:0055001 133 0.091
purine containing compound metabolic process GO:0072521 311 0.091
Mouse
cellular homeostasis GO:0019725 240 0.090
Mouse
negative regulation of immune system process GO:0002683 209 0.090
regulation of intracellular protein transport GO:0033157 82 0.090
cellular response to lipid GO:0071396 145 0.090
regulation of leukocyte proliferation GO:0070663 121 0.089
regulation of actin filament based process GO:0032970 99 0.089
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.089
Mouse
nephron tubule morphogenesis GO:0072078 68 0.089
ribonucleotide catabolic process GO:0009261 208 0.088
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.088
organic cyclic compound catabolic process GO:1901361 295 0.088
Mouse
regulation of hippo signaling GO:0035330 1 0.088
mesenchymal cell development GO:0014031 93 0.088
Mouse
respiratory tube development GO:0030323 167 0.087
regulation of t cell proliferation GO:0042129 92 0.086
cellular response to cytokine stimulus GO:0071345 189 0.086
purine nucleoside triphosphate catabolic process GO:0009146 203 0.085
Mouse
kidney morphogenesis GO:0060993 83 0.085
synapse organization GO:0050808 125 0.083
Mouse
regulation of rho gtpase activity GO:0032319 58 0.082
Mouse
regulation of kinase activity GO:0043549 249 0.081
Mouse
cell cell junction assembly GO:0007043 27 0.081
response to growth factor GO:0070848 198 0.081
protein localization to nucleus GO:0034504 121 0.081
ureteric bud development GO:0001657 94 0.080
axonogenesis GO:0007409 274 0.080
Mouse Worm
extracellular matrix organization GO:0030198 147 0.079
regulation of wnt signaling pathway GO:0030111 123 0.079
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.078
regulation of intracellular transport GO:0032386 159 0.078
neural tube closure GO:0001843 90 0.078
regulation of secretion by cell GO:1903530 249 0.078
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.077
Mouse
regulation of protein import into nucleus GO:0042306 52 0.076
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.076
Mouse
cytoplasmic transport GO:0016482 234 0.076
neural tube formation GO:0001841 108 0.076
mesonephric tubule development GO:0072164 94 0.075
protein localization to organelle GO:0033365 185 0.075
protein import GO:0017038 101 0.075
positive regulation of cytokine production GO:0001819 174 0.074
myeloid leukocyte differentiation GO:0002573 119 0.074
Mouse
establishment of protein localization to membrane GO:0090150 54 0.074
recognition of apoptotic cell GO:0043654 3 0.073
stem cell maintenance GO:0019827 130 0.073
osteoclast differentiation GO:0030316 62 0.073
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.073
regulation of establishment of protein localization GO:0070201 181 0.073
single organism nuclear import GO:1902593 95 0.072
canonical wnt signaling pathway GO:0060070 130 0.072
regulation of cell activation GO:0050865 289 0.072
ribonucleoside metabolic process GO:0009119 245 0.072
Mouse
negative regulation of cellular component organization GO:0051129 194 0.072
Mouse
ameboidal type cell migration GO:0001667 128 0.071
Human Mouse
regulation of protein transport GO:0051223 163 0.071
peptidyl tyrosine modification GO:0018212 145 0.071
Human Mouse Worm
sensory organ morphogenesis GO:0090596 242 0.070
Mouse
glycosyl compound metabolic process GO:1901657 246 0.070
Mouse
mapk cascade GO:0000165 281 0.070
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.069
cytokine production GO:0001816 319 0.068
immune effector process GO:0002252 321 0.067
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.067
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.067
regulation of mapk cascade GO:0043408 248 0.067
Mouse
positive regulation of apoptotic process GO:0043065 217 0.067
Mouse
sterol homeostasis GO:0055092 45 0.067
regionalization GO:0003002 337 0.067
mesenchyme development GO:0060485 152 0.066
Mouse
membrane organization GO:0061024 245 0.066
cellular response to growth factor stimulus GO:0071363 197 0.066
cardiac endothelial cell differentiation GO:0003348 4 0.065
mesonephric epithelium development GO:0072163 94 0.065
t cell proliferation GO:0042098 120 0.064
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.064
regulation of t cell activation GO:0050863 170 0.063
regulation of cellular response to stress GO:0080135 159 0.063
Mouse
oviduct development GO:0060066 3 0.062
nucleocytoplasmic transport GO:0006913 139 0.062
connective tissue development GO:0061448 179 0.062
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.062
positive regulation of protein modification process GO:0031401 299 0.061
Mouse
embryonic skeletal system development GO:0048706 120 0.061
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.061
positive regulation of kinase activity GO:0033674 155 0.060
Mouse
regulation of organ morphogenesis GO:2000027 144 0.060
regulation of stem cell proliferation GO:0072091 78 0.060
retina morphogenesis in camera type eye GO:0060042 45 0.060
cholesterol homeostasis GO:0042632 44 0.059
neuroblast differentiation GO:0014016 2 0.059
embryonic heart tube development GO:0035050 65 0.059
single organismal cell cell adhesion GO:0016337 131 0.059
Mouse
positive regulation of map kinase activity GO:0043406 84 0.059
Mouse
germ cell development GO:0007281 185 0.058
Worm
positive regulation of cell death GO:0010942 224 0.058
Mouse
extracellular structure organization GO:0043062 148 0.058
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.056
regulation of hormone levels GO:0010817 211 0.056
Mouse
plasma membrane organization GO:0007009 90 0.056
central nervous system vasculogenesis GO:0022009 3 0.056
positive regulation of gtpase activity GO:0043547 85 0.055
establishment of protein localization to organelle GO:0072594 118 0.055
cell cell adhesion GO:0098609 41 0.054
response to molecule of bacterial origin GO:0002237 143 0.054
protein targeting GO:0006605 143 0.054
embryonic skeletal system morphogenesis GO:0048704 91 0.053
regulation of rac protein signal transduction GO:0035020 19 0.053
Mouse
regulation of cardiac cell fate specification GO:2000043 1 0.053
skeletal muscle cell differentiation GO:0035914 66 0.053
nuclear transport GO:0051169 139 0.053
regulation of cardioblast differentiation GO:0051890 3 0.053
renal tubule morphogenesis GO:0061333 72 0.052
synaptic vesicle localization GO:0097479 59 0.052
adherens junction organization GO:0034332 28 0.052
regulation of rac gtpase activity GO:0032314 13 0.051
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.051
regulation of protein targeting GO:1903533 61 0.051
leukocyte proliferation GO:0070661 172 0.051
vesicle localization GO:0051648 86 0.050
leukocyte differentiation GO:0002521 342 0.050
Mouse
transmission of nerve impulse GO:0019226 76 0.050
gland development GO:0048732 330 0.050
Mouse
limb development GO:0060173 166 0.050
negative regulation of molecular function GO:0044092 258 0.050
telencephalon development GO:0021537 186 0.050
Mouse
synapse assembly GO:0007416 56 0.050
Mouse
response to acid chemical GO:0001101 111 0.050
compound eye development GO:0048749 1 0.050
glial cell fate determination GO:0007403 3 0.050
mesonephros development GO:0001823 97 0.050
regulation of gliogenesis GO:0014013 50 0.050
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.049
negative regulation of cellular amine metabolic process GO:0033239 1 0.049
positive regulation of protein kinase activity GO:0045860 144 0.049
Mouse
endocytosis GO:0006897 168 0.049
regulation of homeostatic process GO:0032844 182 0.049
Mouse
nitrogen compound transport GO:0071705 271 0.048
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.048
endocardial cell differentiation GO:0060956 4 0.048
dendritic spine organization GO:0097061 26 0.048
Mouse
cell type specific apoptotic process GO:0097285 268 0.048
Mouse
formation of organ boundary GO:0010160 1 0.048
hormone secretion GO:0046879 128 0.048
Mouse
cardiac cell fate specification GO:0060912 2 0.048
appendage morphogenesis GO:0035107 149 0.048
actin filament organization GO:0007015 113 0.048
Mouse
apical junction assembly GO:0043297 15 0.047
neural crest cell differentiation GO:0014033 54 0.047
endomembrane system organization GO:0010256 147 0.047
positive regulation of cell development GO:0010720 237 0.046
Mouse
negative regulation of hepatocyte differentiation GO:0070367 1 0.046
positive regulation of stress activated mapk cascade GO:0032874 48 0.046
Mouse
nuclear import GO:0051170 95 0.046
negative regulation of kinase activity GO:0033673 81 0.045
digestive tract development GO:0048565 190 0.045
Mouse
amide transport GO:0042886 138 0.045
Mouse
regulation of membrane potential GO:0042391 192 0.045
organelle fission GO:0048285 170 0.045
regulation of lymphocyte activation GO:0051249 240 0.044
cardiac septum development GO:0003279 59 0.044
regulation of neural retina development GO:0061074 3 0.044
negative regulation of synapse assembly GO:0051964 3 0.043
Mouse
positive regulation of programmed cell death GO:0043068 218 0.043
Mouse
cardiac muscle tissue development GO:0048738 130 0.042
macromolecule catabolic process GO:0009057 281 0.042
embryonic limb morphogenesis GO:0030326 126 0.042
nephron tubule formation GO:0072079 20 0.042
muscular septum morphogenesis GO:0003150 4 0.042
multicellular organismal homeostasis GO:0048871 164 0.042
negative regulation of cell development GO:0010721 169 0.042
Mouse
angiogenesis GO:0001525 201 0.042
myotube differentiation GO:0014902 105 0.042
neuron death GO:0070997 154 0.042
Mouse
aortic valve morphogenesis GO:0003180 4 0.042
palate development GO:0060021 76 0.042
Mouse
forebrain development GO:0030900 302 0.041
Mouse
establishment of synaptic vesicle localization GO:0097480 57 0.041
bone remodeling GO:0046849 53 0.041
Mouse
stem cell proliferation GO:0072089 117 0.041
negative regulation of phosphorylation GO:0042326 166 0.041
lateral inhibition GO:0046331 1 0.041
dendritic spine development GO:0060996 30 0.041
Mouse
ear development GO:0043583 200 0.041
Mouse
blastocyst development GO:0001824 80 0.041
establishment of organelle localization GO:0051656 122 0.040
establishment of vesicle localization GO:0051650 81 0.040
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.040
locomotory behavior GO:0007626 195 0.040
Mouse
trunk neural crest cell migration GO:0036484 4 0.040
metanephros development GO:0001656 79 0.039
gliogenesis GO:0042063 141 0.039
Mouse
negative regulation of protein modification process GO:0031400 163 0.039
negative regulation of nervous system development GO:0051961 156 0.039
Mouse
blood vessel morphogenesis GO:0048514 285 0.039
tissue homeostasis GO:0001894 115 0.039
regulation of response to wounding GO:1903034 189 0.038
Mouse
nucleoside metabolic process GO:0009116 246 0.038
Mouse
adult behavior GO:0030534 135 0.038
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.038
Mouse
synaptic vesicle transport GO:0048489 57 0.038
somite development GO:0061053 81 0.038
response to organonitrogen compound GO:0010243 246 0.038
negative regulation of cell proliferation GO:0008285 296 0.038
regulation of striated muscle cell differentiation GO:0051153 81 0.038
endodermal cell fate specification GO:0001714 4 0.038
cell fate commitment GO:0045165 210 0.037
cellular chemical homeostasis GO:0055082 215 0.037
Mouse
negative regulation of smooth muscle cell migration GO:0014912 2 0.037
mesonephric tubule morphogenesis GO:0072171 63 0.037
cerebral cortex development GO:0021987 86 0.037
myeloid cell differentiation GO:0030099 233 0.037
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.037
nephron tubule development GO:0072080 84 0.037
response to monosaccharide GO:0034284 67 0.037
Mouse
digestive system development GO:0055123 200 0.036
Mouse
organelle localization GO:0051640 179 0.036
cell matrix adhesion GO:0007160 68 0.036
lymphocyte proliferation GO:0046651 164 0.036
epithelial cell migration GO:0010631 63 0.036
Human Mouse
inner ear morphogenesis GO:0042472 101 0.036
Mouse
regulation of hormone secretion GO:0046883 88 0.036
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.036
bone development GO:0060348 120 0.035
regulation of system process GO:0044057 200 0.035
regulation of cardiac muscle tissue development GO:0055024 31 0.035
somatic stem cell maintenance GO:0035019 47 0.035
cardiac right atrium morphogenesis GO:0003213 3 0.035
positive regulation of jnk cascade GO:0046330 46 0.035
Mouse
forebrain generation of neurons GO:0021872 63 0.035
negative regulation of mitotic cell cycle embryonic GO:0045976 2 0.035
lens morphogenesis in camera type eye GO:0002089 24 0.035
Mouse
tissue remodeling GO:0048771 102 0.035
Mouse
appendage development GO:0048736 166 0.035
heart trabecula morphogenesis GO:0061384 26 0.034
positive regulation of hydrolase activity GO:0051345 148 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.034
negative regulation of ossification GO:0030279 49 0.034
regulation of cell projection organization GO:0031344 206 0.034
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.033
meiotic cell cycle GO:0051321 122 0.033
cellular response to acid chemical GO:0071229 68 0.033
circulatory system process GO:0003013 197 0.033
negative regulation of wnt signaling pathway GO:0030178 73 0.033
positive regulation of nucleoside metabolic process GO:0045979 91 0.033
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.033
female meiosis chromosome segregation GO:0016321 1 0.033
cell maturation GO:0048469 127 0.033
Mouse Worm
regulation of cell cycle GO:0051726 281 0.033
prostate gland development GO:0030850 48 0.032
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.032
cardiac chamber development GO:0003205 108 0.032
dendrite development GO:0016358 115 0.032
Mouse
blood circulation GO:0008015 195 0.032
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.032
positive regulation of intracellular transport GO:0032388 70 0.032
insulin secretion GO:0030073 89 0.032
Mouse
stress activated mapk cascade GO:0051403 80 0.031
Mouse
mitral valve development GO:0003174 4 0.031
learning or memory GO:0007611 148 0.031
Mouse
positive regulation of nervous system development GO:0051962 221 0.031
Mouse
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.031
positive regulation of jun kinase activity GO:0043507 30 0.031
Mouse
regulation of cell cycle process GO:0010564 160 0.031
establishment of endothelial blood brain barrier GO:0014045 3 0.031
peptide transport GO:0015833 133 0.030
Mouse
ensheathment of neurons GO:0007272 76 0.030
fat cell differentiation GO:0045444 160 0.030
muscle contraction GO:0006936 101 0.030
inner ear receptor cell differentiation GO:0060113 61 0.030
pallium development GO:0021543 120 0.030
Mouse
pharynx development GO:0060465 1 0.030
glucose homeostasis GO:0042593 128 0.030
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.030
oxidation reduction process GO:0055114 342 0.030
organelle assembly GO:0070925 177 0.030
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.029
embryonic heart tube morphogenesis GO:0003143 51 0.029
renal vesicle induction GO:0072034 3 0.029
protein localization to plasma membrane GO:0072659 57 0.029
renal outer medulla development GO:0072054 2 0.029
neuronal action potential GO:0019228 54 0.029
memory GO:0007613 58 0.029
negative regulation of osteoblast differentiation GO:0045668 30 0.029
response to retinoic acid GO:0032526 56 0.029
muscle cell proliferation GO:0033002 52 0.029
skeletal muscle fiber development GO:0048741 58 0.029
regulation of lymphocyte proliferation GO:0050670 117 0.029
epithelial cell proliferation GO:0050673 174 0.029
Mouse
negative regulation of stem cell differentiation GO:2000737 14 0.029
ureteric bud morphogenesis GO:0060675 62 0.029
regulation of bmp signaling pathway GO:0030510 60 0.029
regulation of defense response GO:0031347 233 0.029
response to oxygen radical GO:0000305 16 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.029
morphogenesis of a polarized epithelium GO:0001738 37 0.028
peptide secretion GO:0002790 114 0.028
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.028
axon guidance GO:0007411 141 0.028
Mouse Worm
branching involved in ureteric bud morphogenesis GO:0001658 56 0.028
negative regulation of catenin import into nucleus GO:0035414 2 0.028
inter male aggressive behavior GO:0002121 3 0.028
male gonad development GO:0008584 88 0.028
regulation of cartilage development GO:0061035 44 0.028
retina development in camera type eye GO:0060041 119 0.028
trabecula morphogenesis GO:0061383 40 0.028
metanephric nephron development GO:0072210 34 0.028
regulation of organ growth GO:0046620 61 0.028
response to organic cyclic compound GO:0014070 198 0.027
lymphocyte differentiation GO:0030098 242 0.027
oocyte maturation GO:0001556 18 0.027
Worm
nephron morphogenesis GO:0072028 69 0.027
regulation of vesicle mediated transport GO:0060627 139 0.027
establishment of planar polarity GO:0001736 28 0.027
ventricular cardiac muscle cell action potential GO:0086005 4 0.027
somitogenesis GO:0001756 69 0.027
negative regulation of growth GO:0045926 99 0.027
negative regulation of epithelial cell proliferation GO:0050680 64 0.027
oocyte axis specification GO:0007309 2 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
cellular response to organic cyclic compound GO:0071407 87 0.027
cellular response to oxidative stress GO:0034599 76 0.027
metanephric glomerular basement membrane development GO:0072274 1 0.027
outflow tract morphogenesis GO:0003151 53 0.026
regulation of binding GO:0051098 111 0.026
regulation of cell projection assembly GO:0060491 38 0.026
extrinsic apoptotic signaling pathway GO:0097191 126 0.026
positive regulation of cellular component biogenesis GO:0044089 94 0.026
Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.026
regulation of epithelial cell migration GO:0010632 35 0.026
Mouse
positive regulation of cytoplasmic transport GO:1903651 40 0.026
lipid homeostasis GO:0055088 63 0.026
establishment of protein localization to plasma membrane GO:0090002 34 0.026
oligodendrocyte differentiation GO:0048709 53 0.026
positive regulation of intracellular protein transport GO:0090316 42 0.026
sensory perception of mechanical stimulus GO:0050954 107 0.026
central nervous system neuron differentiation GO:0021953 162 0.026
Mouse
myotube cell development GO:0014904 60 0.026
regulation of neuron apoptotic process GO:0043523 122 0.026
Mouse
negative regulation of cell cycle GO:0045786 123 0.026
mechanoreceptor differentiation GO:0042490 67 0.026
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
positive regulation of apoptotic signaling pathway GO:2001235 95 0.026
epidermis morphogenesis GO:0048730 33 0.025
striated muscle cell development GO:0055002 125 0.025
glycerophospholipid metabolic process GO:0006650 71 0.025
Mouse
anion transport GO:0006820 177 0.025
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.025
multicellular organismal signaling GO:0035637 91 0.025
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.025
receptor mediated endocytosis GO:0006898 51 0.025

Ephb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
cardiovascular system disease DOID:1287 0 0.043
musculoskeletal system disease DOID:17 0 0.040
connective tissue disease DOID:65 0 0.040
sensory system disease DOID:0050155 0 0.026
nervous system disease DOID:863 0 0.026