Mus musculus

0 known processes

Trim15

tripartite motif-containing 15

(Aliases: 1810012B10Rik)

Trim15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.153
regulation of defense response GO:0031347 233 0.138
Human Mouse
inorganic ion transmembrane transport GO:0098660 234 0.102
regulation of cellular amine metabolic process GO:0033238 20 0.096
regulation of cellular ketone metabolic process GO:0010565 66 0.092
amine metabolic process GO:0009308 45 0.091
negative regulation of defense response GO:0031348 77 0.085
Mouse
cation transmembrane transport GO:0098655 266 0.079
regulation of cell activation GO:0050865 289 0.072
transmembrane transport GO:0055085 412 0.071
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
immune effector process GO:0002252 321 0.069
Human Mouse
inflammatory response GO:0006954 244 0.068
peptidyl amino acid modification GO:0018193 336 0.064
response to organonitrogen compound GO:0010243 246 0.057
oxidation reduction process GO:0055114 342 0.056
regulation of cytokine production GO:0001817 266 0.056
Human Mouse
regulation of body fluid levels GO:0050878 162 0.053
regulation of mapk cascade GO:0043408 248 0.050
cellular amino acid metabolic process GO:0006520 103 0.049
regulation of lymphocyte activation GO:0051249 240 0.049
cellular ketone metabolic process GO:0042180 84 0.048
regulation of secretion GO:0051046 274 0.047
regulation of inflammatory response GO:0050727 147 0.045
positive regulation of protein phosphorylation GO:0001934 242 0.045
cation transport GO:0006812 399 0.042
regulation of circadian sleep wake cycle GO:0042749 3 0.042
skin development GO:0043588 220 0.041
negative regulation of inflammatory response GO:0050728 61 0.041
nitrogen compound transport GO:0071705 271 0.041
regulation of cell cycle GO:0051726 281 0.041
epidermis development GO:0008544 187 0.040
action potential GO:0001508 78 0.040
positive regulation of innate immune response GO:0045089 80 0.038
Human Mouse
cellular lipid metabolic process GO:0044255 323 0.037
negative regulation of response to wounding GO:1903035 77 0.037
cellular amine metabolic process GO:0044106 44 0.036
synaptic transmission GO:0007268 329 0.035
regulation of transferase activity GO:0051338 263 0.035
leukocyte proliferation GO:0070661 172 0.035
lipid localization GO:0010876 126 0.035
spermatogenesis GO:0007283 284 0.034
negative regulation of molecular function GO:0044092 258 0.034
regulation of protein kinase activity GO:0045859 232 0.034
t cell activation GO:0042110 289 0.034
organic hydroxy compound transport GO:0015850 93 0.034
response to organic cyclic compound GO:0014070 198 0.034
regulation of leukocyte differentiation GO:1902105 159 0.033
regulation of membrane potential GO:0042391 192 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
positive regulation of cell activation GO:0050867 158 0.031
regulation of feeding behavior GO:0060259 3 0.031
multicellular organismal homeostasis GO:0048871 164 0.031
cellular ion homeostasis GO:0006873 165 0.030
peptidyl tyrosine phosphorylation GO:0018108 143 0.030
learning GO:0007612 98 0.030
cellular protein catabolic process GO:0044257 155 0.029
Mouse
divalent metal ion transport GO:0070838 172 0.029
carbohydrate metabolic process GO:0005975 230 0.029
regulation of ion transmembrane transport GO:0034765 119 0.029
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.028
regulation of ion transport GO:0043269 215 0.028
embryonic organ morphogenesis GO:0048562 276 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
Mouse
divalent inorganic cation transport GO:0072511 178 0.028
digestive tract morphogenesis GO:0048546 147 0.028
immune response regulating signaling pathway GO:0002764 125 0.027
Human Mouse
regulation of organelle organization GO:0033043 289 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
sensory organ morphogenesis GO:0090596 242 0.026
sterol homeostasis GO:0055092 45 0.026
mitotic cell cycle GO:0000278 195 0.026
lymphocyte proliferation GO:0046651 164 0.026
metal ion homeostasis GO:0055065 189 0.026
chemotaxis GO:0006935 247 0.026
negative regulation of immune system process GO:0002683 209 0.026
Mouse
mapk cascade GO:0000165 281 0.026
regulation of lymphocyte differentiation GO:0045619 107 0.025
regulation of cellular component size GO:0032535 121 0.025
exocytosis GO:0006887 121 0.025
maintenance of location GO:0051235 89 0.025
sensory perception of mechanical stimulus GO:0050954 107 0.025
regulation of protein kinase b signaling GO:0051896 56 0.025
protein kinase b signaling GO:0043491 74 0.024
wound healing GO:0042060 157 0.024
positive regulation of protein modification process GO:0031401 299 0.024
anion transport GO:0006820 177 0.024
macromolecule catabolic process GO:0009057 281 0.024
Mouse
lipid biosynthetic process GO:0008610 179 0.024
calcium ion transport GO:0006816 159 0.024
positive regulation of transferase activity GO:0051347 167 0.024
cellular response to biotic stimulus GO:0071216 92 0.023
cellular homeostasis GO:0019725 240 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
response to radiation GO:0009314 165 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
glycoprotein metabolic process GO:0009100 116 0.023
response to amino acid GO:0043200 37 0.023
rho protein signal transduction GO:0007266 32 0.023
cellular response to growth factor stimulus GO:0071363 197 0.022
molting cycle GO:0042303 90 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
innate immune response GO:0045087 157 0.022
Human Mouse
protein maturation GO:0051604 176 0.022
male gamete generation GO:0048232 285 0.022
macromolecule glycosylation GO:0043413 55 0.022
positive regulation of defense response GO:0031349 124 0.022
Human Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
positive regulation of t cell activation GO:0050870 101 0.022
regulation of protein catabolic process GO:0042176 108 0.022
Mouse
cellular protein complex assembly GO:0043623 116 0.022
Mouse
negative regulation of cell development GO:0010721 169 0.022
Mouse
regulation of secretion by cell GO:1903530 249 0.022
striated muscle tissue development GO:0014706 293 0.022
circadian sleep wake cycle rem sleep GO:0042747 1 0.022
leukocyte differentiation GO:0002521 342 0.022
regulation of proteolysis GO:0030162 164 0.022
norepinephrine secretion GO:0048243 2 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
compound eye development GO:0048749 1 0.021
cell type specific apoptotic process GO:0097285 268 0.021
calcium ion homeostasis GO:0055074 127 0.021
cytokine production GO:0001816 319 0.021
Human Mouse
protein processing GO:0016485 163 0.021
regulation of t cell activation GO:0050863 170 0.021
norepinephrine transport GO:0015874 2 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
regulation of system process GO:0044057 200 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
cell chemotaxis GO:0060326 81 0.021
endocytosis GO:0006897 168 0.021
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.021
response to lipopolysaccharide GO:0032496 128 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
adult behavior GO:0030534 135 0.020
keratinocyte differentiation GO:0030216 48 0.020
response to acid chemical GO:0001101 111 0.020
regulation of neuron differentiation GO:0045664 281 0.020
multi multicellular organism process GO:0044706 109 0.020
apoptotic signaling pathway GO:0097190 306 0.020
tube formation GO:0035148 140 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
cation homeostasis GO:0055080 212 0.020
ameboidal type cell migration GO:0001667 128 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
positive regulation of ion transport GO:0043270 65 0.020
acetylcholine secretion neurotransmission GO:0014055 2 0.020
circadian rhythm GO:0007623 114 0.020
regulation of response to wounding GO:1903034 189 0.020
positive regulation of cytokine production GO:0001819 174 0.020
Human
organic cyclic compound catabolic process GO:1901361 295 0.019
b cell activation GO:0042113 161 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
lipid transport GO:0006869 98 0.019
lymphocyte differentiation GO:0030098 242 0.019
actin filament polymerization GO:0030041 44 0.019
negative regulation of cell cycle GO:0045786 123 0.019
learning or memory GO:0007611 148 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.018
regulation of interleukin 6 production GO:0032675 55 0.018
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
cellular chemical homeostasis GO:0055082 215 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
negative regulation of hydrolase activity GO:0051346 71 0.018
muscle tissue development GO:0060537 308 0.018
heterocycle catabolic process GO:0046700 280 0.018
anatomical structure homeostasis GO:0060249 145 0.018
protein polymerization GO:0051258 57 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
Mouse
protein glycosylation GO:0006486 55 0.018
cellular response to amino acid stimulus GO:0071230 29 0.018
response to insulin GO:0032868 100 0.017
organelle localization GO:0051640 179 0.017
regulation of homeostatic process GO:0032844 182 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
Mouse
membrane organization GO:0061024 245 0.017
cellular response to acid chemical GO:0071229 68 0.017
ear development GO:0043583 200 0.017
regulation of transmembrane transport GO:0034762 128 0.017
glycosylation GO:0070085 62 0.017
nucleotide catabolic process GO:0009166 217 0.017
regulation of protein localization GO:0032880 231 0.017
sensory perception GO:0007600 245 0.017
positive regulation of leukocyte differentiation GO:1902107 86 0.017
interleukin 6 production GO:0032635 58 0.016
Mouse
detection of external stimulus GO:0009581 61 0.016
skeletal system development GO:0001501 356 0.016
positive regulation of dopamine secretion GO:0033603 2 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
cell adhesion GO:0007155 329 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
translation GO:0006412 93 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
spermatid differentiation GO:0048515 115 0.016
germ cell development GO:0007281 185 0.016
organ growth GO:0035265 117 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.015
regulation of cell migration GO:0030334 219 0.015
gland development GO:0048732 330 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
regulation of cell growth GO:0001558 91 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
muscle cell differentiation GO:0042692 261 0.015
regulation of innate immune response GO:0045088 91 0.015
Human Mouse
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.015
small molecule biosynthetic process GO:0044283 132 0.015
toll like receptor signaling pathway GO:0002224 38 0.015
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
Mouse
detection of mechanical stimulus GO:0050982 27 0.015
osteoclast differentiation GO:0030316 62 0.015
response to growth factor GO:0070848 198 0.015
regulation of kinase activity GO:0043549 249 0.015
renal sodium excretion GO:0035812 3 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
asymmetric stem cell division GO:0098722 3 0.015
regulation of ossification GO:0030278 112 0.014
protein catabolic process GO:0030163 221 0.014
Mouse
intracellular protein transport GO:0006886 204 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.014
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
conditioned taste aversion GO:0001661 4 0.014
regulation of muscle tissue development GO:1901861 97 0.014
regulation of hydrolase activity GO:0051336 246 0.014
generation of ovulation cycle rhythm GO:0060112 1 0.014
regulation of reproductive process GO:2000241 66 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of vasculature development GO:1901342 88 0.014
regulation of map kinase activity GO:0043405 120 0.014
positive regulation of lymphocyte differentiation GO:0045621 61 0.014
muscle cell development GO:0055001 133 0.014
defense response to other organism GO:0098542 197 0.014
Human Mouse
positive regulation of catecholamine secretion GO:0033605 2 0.014
negative regulation of leukocyte differentiation GO:1902106 51 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
digestive tract development GO:0048565 190 0.014
ras protein signal transduction GO:0007265 77 0.014
nuclear division GO:0000280 158 0.014
transmission of nerve impulse GO:0019226 76 0.014
actin polymerization or depolymerization GO:0008154 54 0.013
heart contraction GO:0060047 93 0.013
regionalization GO:0003002 337 0.013
epithelial cell proliferation GO:0050673 174 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
regulation of t cell differentiation GO:0045580 83 0.013
cognition GO:0050890 149 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
camera type eye development GO:0043010 266 0.013
sperm motility GO:0030317 47 0.013
fat cell differentiation GO:0045444 160 0.013
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.013
positive regulation of secretion GO:0051047 130 0.013
blastocyst development GO:0001824 80 0.013
lipid homeostasis GO:0055088 63 0.013
neuron death GO:0070997 154 0.013
single fertilization GO:0007338 82 0.013
response to food GO:0032094 17 0.013
regulation of hormone levels GO:0010817 211 0.013
alcohol metabolic process GO:0006066 116 0.013
t cell differentiation GO:0030217 174 0.013
extracellular matrix organization GO:0030198 147 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.012
Mouse
regulation of cell motility GO:2000145 236 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
inorganic anion transport GO:0015698 43 0.012
associative learning GO:0008306 61 0.012
placenta development GO:0001890 140 0.012
locomotory behavior GO:0007626 195 0.012
neuron neuron synaptic transmission GO:0007270 69 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
embryonic placenta development GO:0001892 98 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
Mouse
cell activation involved in immune response GO:0002263 126 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
detection of abiotic stimulus GO:0009582 60 0.012
response to hypoxia GO:0001666 58 0.012
response to peptide GO:1901652 136 0.012
wnt signaling pathway GO:0016055 188 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
protein autophosphorylation GO:0046777 61 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
ossification GO:0001503 216 0.012
dendrite development GO:0016358 115 0.012
positive regulation of protein transport GO:0051222 93 0.012
regulation of epidermis development GO:0045682 33 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
cellular response to lipid GO:0071396 145 0.012
macromolecule methylation GO:0043414 120 0.012
amide transport GO:0042886 138 0.012
regulation of action potential GO:0098900 4 0.012
membrane depolarization GO:0051899 64 0.012
regulation of canonical wnt signaling pathway GO:0060828 82 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of b cell activation GO:0050864 81 0.012
urogenital system development GO:0001655 261 0.012
protein ubiquitination GO:0016567 171 0.012
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.012
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.012
second messenger mediated signaling GO:0019932 73 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of multi organism process GO:0043900 111 0.012
Human Mouse
microtubule based process GO:0007017 236 0.011
detection of stimulus GO:0051606 84 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
negative regulation of keratinocyte differentiation GO:0045617 4 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
angiogenesis GO:0001525 201 0.011
response to decreased oxygen levels GO:0036293 59 0.011
regulation of tumor necrosis factor production GO:0032680 49 0.011
Mouse
t cell proliferation GO:0042098 120 0.011
leukocyte migration GO:0050900 124 0.011
peptide hormone secretion GO:0030072 109 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
oocyte construction GO:0007308 2 0.011
skeletal system morphogenesis GO:0048705 203 0.011
negative regulation of protein processing GO:0010955 79 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
leukocyte chemotaxis GO:0030595 69 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
dephosphorylation GO:0016311 129 0.011
glucose metabolic process GO:0006006 92 0.011
bone development GO:0060348 120 0.011
regulation of protein processing GO:0070613 96 0.011
positive regulation of leukocyte proliferation GO:0070665 73 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.011
Mouse
regulation of calcium ion transport GO:0051924 69 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
hexose metabolic process GO:0019318 98 0.011
aromatic compound catabolic process GO:0019439 286 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
digestive system development GO:0055123 200 0.011
positive regulation of cell development GO:0010720 237 0.011
gastrulation GO:0007369 116 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
immune response activating signal transduction GO:0002757 116 0.011
Human Mouse
olfactory learning GO:0008355 2 0.011
membrane hyperpolarization GO:0060081 21 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
sulfur compound metabolic process GO:0006790 100 0.011
establishment of organelle localization GO:0051656 122 0.011
antibacterial peptide biosynthetic process GO:0002780 2 0.010
positive regulation of kinase activity GO:0033674 155 0.010
hair cycle GO:0042633 90 0.010
regulation of actin filament length GO:0030832 45 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
pattern recognition receptor signaling pathway GO:0002221 47 0.010
Human Mouse
peptide secretion GO:0002790 114 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
purine containing compound metabolic process GO:0072521 311 0.010
negative regulation of protein modification process GO:0031400 163 0.010
body fluid secretion GO:0007589 53 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
negative regulation of cell activation GO:0050866 111 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
blood circulation GO:0008015 195 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
tissue remodeling GO:0048771 102 0.010
insulin receptor signaling pathway GO:0008286 49 0.010
organic acid biosynthetic process GO:0016053 86 0.010
regulation of t cell proliferation GO:0042129 92 0.010
positive regulation of organelle organization GO:0010638 128 0.010
coagulation GO:0050817 78 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
tissue homeostasis GO:0001894 115 0.010

Trim15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
nervous system disease DOID:863 0 0.012
sensory system disease DOID:0050155 0 0.010