Mus musculus

41 known processes

Ube2k

ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)

(Aliases: Lig,D5Ertd601e,E2-25k,AW492011,Hypg,Hip2)

Ube2k biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein catabolic process GO:0030163 221 0.108
protein modification by small protein conjugation GO:0032446 187 0.068
Human Yeast
modification dependent macromolecule catabolic process GO:0043632 133 0.059
cellular amine metabolic process GO:0044106 44 0.050
amine metabolic process GO:0009308 45 0.047
peptidyl amino acid modification GO:0018193 336 0.047
macromolecule catabolic process GO:0009057 281 0.045
nuclear division GO:0000280 158 0.045
modification dependent protein catabolic process GO:0019941 133 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
male gamete generation GO:0048232 285 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.042
Human Yeast
cellular protein catabolic process GO:0044257 155 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
regulation of cellular amine metabolic process GO:0033238 20 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
cellular ketone metabolic process GO:0042180 84 0.038
cytoplasmic transport GO:0016482 234 0.038
synaptic transmission GO:0007268 329 0.037
aromatic compound catabolic process GO:0019439 286 0.037
regulation of organelle organization GO:0033043 289 0.037
cellular response to dna damage stimulus GO:0006974 207 0.034
nucleotide metabolic process GO:0009117 332 0.034
regulation of cellular component biogenesis GO:0044087 181 0.034
membrane organization GO:0061024 245 0.033
cation transport GO:0006812 399 0.033
intracellular protein transport GO:0006886 204 0.032
protein ubiquitination GO:0016567 171 0.032
Human Yeast
organelle fission GO:0048285 170 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
heterocycle catabolic process GO:0046700 280 0.030
protein localization to organelle GO:0033365 185 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
ribose phosphate metabolic process GO:0019693 291 0.028
purine containing compound metabolic process GO:0072521 311 0.028
transmembrane transport GO:0055085 412 0.028
regulation of protein localization GO:0032880 231 0.028
muscle cell differentiation GO:0042692 261 0.027
negative regulation of molecular function GO:0044092 258 0.027
cytokine production GO:0001816 319 0.027
mitochondrion organization GO:0007005 134 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
dna metabolic process GO:0006259 303 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
chromatin organization GO:0006325 206 0.026
organelle localization GO:0051640 179 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
oxidation reduction process GO:0055114 342 0.025
spermatogenesis GO:0007283 284 0.025
mitotic cell cycle GO:0000278 195 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
response to organonitrogen compound GO:0010243 246 0.025
chromatin modification GO:0016568 187 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
mitotic cell cycle process GO:1903047 159 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
dna repair GO:0006281 107 0.024
actin cytoskeleton organization GO:0030036 220 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
positive regulation of apoptotic process GO:0043065 217 0.023
meiotic cell cycle GO:0051321 122 0.023
endomembrane system organization GO:0010256 147 0.023
organophosphate catabolic process GO:0046434 232 0.023
organic cyclic compound catabolic process GO:1901361 295 0.022
nucleoside metabolic process GO:0009116 246 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
nuclear transport GO:0051169 139 0.022
purine containing compound catabolic process GO:0072523 213 0.022
mapk cascade GO:0000165 281 0.022
striated muscle tissue development GO:0014706 293 0.022
regulation of proteolysis GO:0030162 164 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
mrna metabolic process GO:0016071 84 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
cellular homeostasis GO:0019725 240 0.021
regulation of intracellular transport GO:0032386 159 0.021
organelle assembly GO:0070925 177 0.021
ras protein signal transduction GO:0007265 77 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
microtubule based process GO:0007017 236 0.021
carbohydrate metabolic process GO:0005975 230 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
regulation of mapk cascade GO:0043408 248 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
protein targeting GO:0006605 143 0.021
regulation of cell cycle GO:0051726 281 0.021
Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
regulation of cell migration GO:0030334 219 0.020
regulation of membrane potential GO:0042391 192 0.020
muscle tissue development GO:0060537 308 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
proteasomal protein catabolic process GO:0010498 98 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
rna processing GO:0006396 105 0.020
cellular protein complex assembly GO:0043623 116 0.020
positive regulation of cell death GO:0010942 224 0.020
apoptotic signaling pathway GO:0097190 306 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
regulation of transferase activity GO:0051338 263 0.020
negative regulation of phosphorylation GO:0042326 166 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
regulation of cell motility GO:2000145 236 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
regulation of hormone levels GO:0010817 211 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
regulation of protein catabolic process GO:0042176 108 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
endocytosis GO:0006897 168 0.019
ion transmembrane transport GO:0034220 361 0.019
positive regulation of protein modification process GO:0031401 299 0.019
response to radiation GO:0009314 165 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
regulation of kinase activity GO:0043549 249 0.018
protein polymerization GO:0051258 57 0.018
establishment of organelle localization GO:0051656 122 0.018
regulation of ion transport GO:0043269 215 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
locomotory behavior GO:0007626 195 0.018
cellular lipid metabolic process GO:0044255 323 0.018
regulation of secretion GO:0051046 274 0.018
nucleoside catabolic process GO:0009164 206 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
regulation of anatomical structure size GO:0090066 178 0.017
nitrogen compound transport GO:0071705 271 0.017
inflammatory response GO:0006954 244 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
protein localization to membrane GO:0072657 108 0.017
sensory perception GO:0007600 245 0.017
positive regulation of organelle organization GO:0010638 128 0.017
divalent metal ion transport GO:0070838 172 0.017
regulation of system process GO:0044057 200 0.017
immune effector process GO:0002252 321 0.017
compound eye development GO:0048749 1 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
response to organic cyclic compound GO:0014070 198 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
mitochondrion distribution GO:0048311 4 0.017
histone modification GO:0016570 159 0.017
inorganic ion transmembrane transport GO:0098660 234 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
protein processing GO:0016485 163 0.016
cell division GO:0051301 120 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
stem cell differentiation GO:0048863 268 0.016
regulation of protein kinase activity GO:0045859 232 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
regulation of protein transport GO:0051223 163 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
maintenance of location GO:0051235 89 0.016
protein import GO:0017038 101 0.016
regulation of defense response GO:0031347 233 0.016
nucleotide catabolic process GO:0009166 217 0.015
protein polyubiquitination GO:0000209 33 0.015
Human
negative regulation of organelle organization GO:0010639 90 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
positive regulation of cell development GO:0010720 237 0.015
skeletal muscle organ development GO:0060538 163 0.015
defense response to other organism GO:0098542 197 0.015
regulation of cell activation GO:0050865 289 0.015
transmission of nerve impulse GO:0019226 76 0.015
protein maturation GO:0051604 176 0.015
meiotic nuclear division GO:0007126 115 0.015
meiotic cell cycle process GO:1903046 77 0.015
covalent chromatin modification GO:0016569 163 0.015
regulation of secretion by cell GO:1903530 249 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
cellular chemical homeostasis GO:0055082 215 0.015
response to peptide GO:1901652 136 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
regulation of hydrolase activity GO:0051336 246 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
intracellular mrna localization GO:0008298 4 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.014
circulatory system process GO:0003013 197 0.014
regulation of multi organism process GO:0043900 111 0.014
single organism nuclear import GO:1902593 95 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
anion transport GO:0006820 177 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
cell adhesion GO:0007155 329 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
camera type eye development GO:0043010 266 0.014
regulation of peptidase activity GO:0052547 96 0.014
nuclear import GO:0051170 95 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
muscle system process GO:0003012 141 0.013
fertilization GO:0009566 127 0.013
regulation of cellular component size GO:0032535 121 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
response to growth factor GO:0070848 198 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
methylation GO:0032259 134 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
leukocyte proliferation GO:0070661 172 0.013
divalent inorganic cation transport GO:0072511 178 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
lipid biosynthetic process GO:0008610 179 0.013
cell growth GO:0016049 130 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
gland development GO:0048732 330 0.013
cation homeostasis GO:0055080 212 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
regulation of protein processing GO:0070613 96 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
multicellular organismal signaling GO:0035637 91 0.013
negative regulation of immune system process GO:0002683 209 0.013
forebrain development GO:0030900 302 0.013
regulation of cell cycle process GO:0010564 160 0.013
dephosphorylation GO:0016311 129 0.013
response to light stimulus GO:0009416 135 0.013
carbohydrate homeostasis GO:0033500 128 0.013
chemotaxis GO:0006935 247 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
cellular response to lipid GO:0071396 145 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
positive regulation of nervous system development GO:0051962 221 0.013
glucose homeostasis GO:0042593 128 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
leukocyte differentiation GO:0002521 342 0.012
sequestering of calcium ion GO:0051208 18 0.012
plasma membrane organization GO:0007009 90 0.012
positive regulation of protein transport GO:0051222 93 0.012
response to lipopolysaccharide GO:0032496 128 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of cellular response to stress GO:0080135 159 0.012
regulation of response to wounding GO:1903034 189 0.012
t cell activation GO:0042110 289 0.012
germ cell development GO:0007281 185 0.012
meiosis i GO:0007127 60 0.012
negative regulation of protein modification process GO:0031400 163 0.012
cellular ion homeostasis GO:0006873 165 0.012
action potential GO:0001508 78 0.012
protein import into nucleus GO:0006606 95 0.012
response to peptide hormone GO:0043434 127 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
response to oxidative stress GO:0006979 123 0.012
myosin filament assembly GO:0031034 2 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
innate immune response GO:0045087 157 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
lateral inhibition GO:0046331 1 0.012
regulation of transmembrane transport GO:0034762 128 0.012
macromolecule methylation GO:0043414 120 0.012
ossification GO:0001503 216 0.012
positive regulation of transferase activity GO:0051347 167 0.012
homeostasis of number of cells GO:0048872 210 0.012
muscle contraction GO:0006936 101 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
calcium ion transport GO:0006816 159 0.012
negative regulation of cell development GO:0010721 169 0.012
regulation of cytokine production GO:0001817 266 0.012
response to extracellular stimulus GO:0009991 127 0.012
developmental maturation GO:0021700 193 0.011
adult behavior GO:0030534 135 0.011
regulation of cell projection organization GO:0031344 206 0.011
learning or memory GO:0007611 148 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
synapse organization GO:0050808 125 0.011
anatomical structure homeostasis GO:0060249 145 0.011
response to inorganic substance GO:0010035 96 0.011
axonogenesis GO:0007409 274 0.011
negative regulation of cell cycle GO:0045786 123 0.011
rhythmic process GO:0048511 174 0.011
dendrite development GO:0016358 115 0.011
vesicle localization GO:0051648 86 0.011
oocyte construction GO:0007308 2 0.011
blood circulation GO:0008015 195 0.011
telencephalon development GO:0021537 186 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
chromosome segregation GO:0007059 48 0.011
lymphocyte proliferation GO:0046651 164 0.011
protein secretion GO:0009306 111 0.011
regulation of neuron differentiation GO:0045664 281 0.011
regulation of metal ion transport GO:0010959 106 0.011
spermatid differentiation GO:0048515 115 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
leukocyte mediated immunity GO:0002443 174 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
respiratory system development GO:0060541 190 0.011
cell maturation GO:0048469 127 0.011
cellular response to external stimulus GO:0071496 88 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of histone modification GO:0031056 56 0.011
digestive system development GO:0055123 200 0.011
metal ion homeostasis GO:0055065 189 0.011
regulation of homeostatic process GO:0032844 182 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
epithelial cell development GO:0002064 159 0.011
myosin filament organization GO:0031033 3 0.011
tissue homeostasis GO:0001894 115 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
regulation of protein complex assembly GO:0043254 83 0.011
myotube differentiation GO:0014902 105 0.011
fatty acid metabolic process GO:0006631 121 0.011
cofactor metabolic process GO:0051186 80 0.010
oocyte axis specification GO:0007309 2 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
organic anion transport GO:0015711 137 0.010
regulation of protein maturation GO:1903317 96 0.010
epithelial cell proliferation GO:0050673 174 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
fat cell differentiation GO:0045444 160 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
localization within membrane GO:0051668 4 0.010
jnk cascade GO:0007254 72 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
regulation of cellular protein catabolic process GO:1903362 61 0.010
positive regulation of dna templated transcription elongation GO:0032786 2 0.010
wound healing GO:0042060 157 0.010
response to nutrient levels GO:0031667 109 0.010
neuron death GO:0070997 154 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
regulation of translation GO:0006417 71 0.010
alcohol metabolic process GO:0006066 116 0.010

Ube2k disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.013