Mus musculus

0 known processes

Ube2o

ubiquitin-conjugating enzyme E2O

(Aliases: E2-230K,B230113M03Rik,9630022H21,mKIAA1734)

Ube2o biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 281 0.117
chromatin organization GO:0006325 206 0.110
macromolecule catabolic process GO:0009057 281 0.100
protein modification by small protein conjugation GO:0032446 187 0.099
Human
male gamete generation GO:0048232 285 0.097
mitotic cell cycle GO:0000278 195 0.095
spermatogenesis GO:0007283 284 0.094
purine nucleotide metabolic process GO:0006163 302 0.086
negative regulation of protein metabolic process GO:0051248 282 0.086
peptidyl amino acid modification GO:0018193 336 0.083
cellular macromolecule catabolic process GO:0044265 206 0.080
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.080
protein catabolic process GO:0030163 221 0.080
axonogenesis GO:0007409 274 0.073
intracellular protein transport GO:0006886 204 0.068
negative regulation of cellular protein metabolic process GO:0032269 247 0.065
negative regulation of protein modification process GO:0031400 163 0.063
cytoplasmic transport GO:0016482 234 0.059
endocytosis GO:0006897 168 0.055
positive regulation of cellular catabolic process GO:0031331 148 0.055
cellular ketone metabolic process GO:0042180 84 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
protein targeting GO:0006605 143 0.053
cell growth GO:0016049 130 0.052
protein ubiquitination GO:0016567 171 0.052
Human
oocyte axis specification GO:0007309 2 0.049
ras protein signal transduction GO:0007265 77 0.048
chemotaxis GO:0006935 247 0.048
histone modification GO:0016570 159 0.047
proteasomal protein catabolic process GO:0010498 98 0.047
cellular protein catabolic process GO:0044257 155 0.047
modification dependent protein catabolic process GO:0019941 133 0.046
negative regulation of molecular function GO:0044092 258 0.046
rna processing GO:0006396 105 0.046
cell division GO:0051301 120 0.045
habituation GO:0046959 3 0.045
regulation of cell growth GO:0001558 91 0.044
regulation of cellular catabolic process GO:0031329 242 0.043
heterocycle catabolic process GO:0046700 280 0.043
negative regulation of intracellular signal transduction GO:1902532 167 0.043
positive regulation of protein phosphorylation GO:0001934 242 0.042
organophosphate biosynthetic process GO:0090407 122 0.042
modification dependent macromolecule catabolic process GO:0043632 133 0.041
regulation of transferase activity GO:0051338 263 0.041
microtubule based process GO:0007017 236 0.041
negative regulation of protein processing GO:0010955 79 0.041
carbohydrate derivative biosynthetic process GO:1901137 183 0.041
negative regulation of growth GO:0045926 99 0.039
ubiquitin dependent protein catabolic process GO:0006511 129 0.039
establishment of organelle localization GO:0051656 122 0.038
negative regulation of synapse assembly GO:0051964 3 0.038
chromatin modification GO:0016568 187 0.038
regulation of neuron projection development GO:0010975 169 0.037
organelle localization GO:0051640 179 0.037
nucleoside triphosphate catabolic process GO:0009143 205 0.036
transmembrane transport GO:0055085 412 0.036
multicellular organismal homeostasis GO:0048871 164 0.036
protein modification by small protein conjugation or removal GO:0070647 207 0.036
Human
protein localization to organelle GO:0033365 185 0.036
sensory organ morphogenesis GO:0090596 242 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.035
posttranscriptional regulation of gene expression GO:0010608 155 0.035
locomotory behavior GO:0007626 195 0.035
myotube differentiation GO:0014902 105 0.035
regionalization GO:0003002 337 0.035
intracellular mrna localization GO:0008298 4 0.034
regulation of mapk cascade GO:0043408 248 0.034
anatomical structure homeostasis GO:0060249 145 0.034
purine containing compound metabolic process GO:0072521 311 0.034
regulation of proteolysis GO:0030162 164 0.034
response to reactive oxygen species GO:0000302 56 0.034
purine nucleoside metabolic process GO:0042278 241 0.033
regulation of protein kinase activity GO:0045859 232 0.033
positive regulation of nervous system development GO:0051962 221 0.033
mrna metabolic process GO:0016071 84 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
response to organonitrogen compound GO:0010243 246 0.032
establishment of protein localization to organelle GO:0072594 118 0.032
establishment of vesicle localization GO:0051650 81 0.031
purine nucleoside triphosphate catabolic process GO:0009146 203 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
compound eye development GO:0048749 1 0.031
response to peptide GO:1901652 136 0.031
small gtpase mediated signal transduction GO:0007264 97 0.030
response to peptide hormone GO:0043434 127 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
microtubule cytoskeleton organization GO:0000226 157 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
carbohydrate metabolic process GO:0005975 230 0.029
negative regulation of translational initiation GO:0045947 4 0.029
negative regulation of protein maturation GO:1903318 79 0.029
dephosphorylation GO:0016311 129 0.029
synaptic transmission GO:0007268 329 0.029
mapk cascade GO:0000165 281 0.029
phagocytosis GO:0006909 66 0.029
regulation of cellular response to stress GO:0080135 159 0.029
nucleotide metabolic process GO:0009117 332 0.028
olfactory learning GO:0008355 2 0.028
actin cytoskeleton organization GO:0030036 220 0.028
axon guidance GO:0007411 141 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
bone development GO:0060348 120 0.028
positive regulation of dna templated transcription elongation GO:0032786 2 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
covalent chromatin modification GO:0016569 163 0.027
camera type eye development GO:0043010 266 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of protein maturation GO:1903317 96 0.027
asymmetric stem cell division GO:0098722 3 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.027
cellular amine metabolic process GO:0044106 44 0.026
regulation of kinase activity GO:0043549 249 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
muscle fiber development GO:0048747 76 0.026
regulation of hydrolase activity GO:0051336 246 0.026
regulation of protein processing GO:0070613 96 0.026
regulation of intracellular transport GO:0032386 159 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.026
oocyte construction GO:0007308 2 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
autophagy GO:0006914 45 0.025
metencephalon development GO:0022037 89 0.025
rho protein signal transduction GO:0007266 32 0.025
spermatid differentiation GO:0048515 115 0.025
cation transport GO:0006812 399 0.025
neuron projection guidance GO:0097485 141 0.024
protein localization to membrane GO:0072657 108 0.024
stem cell differentiation GO:0048863 268 0.024
regulation of binding GO:0051098 111 0.024
nucleoside metabolic process GO:0009116 246 0.024
ion transmembrane transport GO:0034220 361 0.024
gtp metabolic process GO:0046039 144 0.024
establishment or maintenance of cell polarity GO:0007163 86 0.024
spermatid development GO:0007286 108 0.024
guanosine containing compound metabolic process GO:1901068 144 0.023
macroautophagy GO:0016236 21 0.023
cellular response to peptide GO:1901653 92 0.023
negative regulation of carbohydrate metabolic process GO:0045912 19 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
rna localization GO:0006403 23 0.023
myeloid cell differentiation GO:0030099 233 0.023
immune effector process GO:0002252 321 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
regulation of anatomical structure size GO:0090066 178 0.022
skeletal system morphogenesis GO:0048705 203 0.022
respiratory system development GO:0060541 190 0.022
asymmetric neuroblast division GO:0055059 1 0.022
regulation of system process GO:0044057 200 0.022
cell type specific apoptotic process GO:0097285 268 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
regulation of translation GO:0006417 71 0.021
regulation of translational initiation GO:0006446 15 0.021
axoneme assembly GO:0035082 15 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
meiotic cell cycle GO:0051321 122 0.021
negative regulation of proteolysis GO:0045861 74 0.021
tissue homeostasis GO:0001894 115 0.021
development of primary sexual characteristics GO:0045137 143 0.020
myeloid cell homeostasis GO:0002262 114 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
response to insulin GO:0032868 100 0.020
heterochromatin assembly GO:0031507 2 0.020
rna splicing GO:0008380 54 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
regulation of cell cycle process GO:0010564 160 0.020
histone methylation GO:0016571 71 0.020
protein oligomerization GO:0051259 67 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
positive regulation of protein modification process GO:0031401 299 0.020
homeostasis of number of cells GO:0048872 210 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
regulation of protein localization GO:0032880 231 0.020
apoptotic signaling pathway GO:0097190 306 0.020
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.019
striated muscle tissue development GO:0014706 293 0.019
male meiosis GO:0007140 37 0.019
anion transport GO:0006820 177 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
mitochondrion transport along microtubule GO:0047497 3 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
meiotic cell cycle process GO:1903046 77 0.019
male courtship behavior GO:0008049 2 0.019
multicellular organism growth GO:0035264 161 0.019
regulation of homeostatic process GO:0032844 182 0.019
regulation of muscle tissue development GO:1901861 97 0.019
mitotic cell cycle process GO:1903047 159 0.019
regulation of neuron differentiation GO:0045664 281 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
positive regulation of proteolysis GO:0045862 85 0.019
regulation of cytoplasmic transport GO:1903649 112 0.018
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.018
regulation of myotube differentiation GO:0010830 62 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
response to organic cyclic compound GO:0014070 198 0.018
methylation GO:0032259 134 0.018
sensory system development GO:0048880 3 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
muscle cell differentiation GO:0042692 261 0.018
neural retina development GO:0003407 41 0.018
nuclear import GO:0051170 95 0.018
organelle assembly GO:0070925 177 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
positive regulation of transferase activity GO:0051347 167 0.018
negative regulation of phosphorylation GO:0042326 166 0.017
gtp catabolic process GO:0006184 143 0.017
membrane organization GO:0061024 245 0.017
cellular lipid metabolic process GO:0044255 323 0.017
regulation of cellular protein catabolic process GO:1903362 61 0.017
vesicle localization GO:0051648 86 0.017
skin development GO:0043588 220 0.017
positive regulation of cellular protein catabolic process GO:1903364 34 0.017
dna metabolic process GO:0006259 303 0.017
oxidation reduction process GO:0055114 342 0.017
protein processing GO:0016485 163 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.016
tissue remodeling GO:0048771 102 0.016
lymphocyte differentiation GO:0030098 242 0.016
negative regulation of cell growth GO:0030308 44 0.016
purine containing compound biosynthetic process GO:0072522 70 0.016
neural precursor cell proliferation GO:0061351 121 0.016
purine containing compound catabolic process GO:0072523 213 0.016
single organism nuclear import GO:1902593 95 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
cell maturation GO:0048469 127 0.016
regulation of metal ion transport GO:0010959 106 0.016
response to growth factor GO:0070848 198 0.016
cellular response to insulin stimulus GO:0032869 78 0.016
cellularization GO:0007349 1 0.016
translational initiation GO:0006413 24 0.016
organ growth GO:0035265 117 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
carbohydrate biosynthetic process GO:0016051 74 0.015
regulation of erk1 and erk2 cascade GO:0070372 71 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
cognition GO:0050890 149 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
regulation of cellular response to growth factor stimulus GO:0090287 82 0.015
skeletal muscle fiber development GO:0048741 58 0.015
meiosis i GO:0007127 60 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
regulation of carbohydrate biosynthetic process GO:0043255 40 0.015
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
rab protein signal transduction GO:0032482 1 0.015
nuclear transport GO:0051169 139 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
cellular homeostasis GO:0019725 240 0.015
leukocyte differentiation GO:0002521 342 0.015
cartilage development GO:0051216 140 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
regulation of synapse structural plasticity GO:0051823 4 0.014
jnk cascade GO:0007254 72 0.014
negative regulation of triglyceride metabolic process GO:0090209 4 0.014
histone acetylation GO:0016573 41 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
hindbrain development GO:0030902 128 0.014
regulation of protein binding GO:0043393 60 0.014
developmental maturation GO:0021700 193 0.014
nitrogen compound transport GO:0071705 271 0.014
positive regulation of cell development GO:0010720 237 0.014
protein localization to nucleus GO:0034504 121 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
monosaccharide metabolic process GO:0005996 106 0.014
aromatic compound catabolic process GO:0019439 286 0.014
myotube cell development GO:0014904 60 0.014
phospholipid metabolic process GO:0006644 87 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
sensory perception GO:0007600 245 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
establishment of rna localization GO:0051236 18 0.014
protein autophosphorylation GO:0046777 61 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
exocytosis GO:0006887 121 0.014
mrna processing GO:0006397 63 0.014
organic anion transport GO:0015711 137 0.013
second messenger mediated signaling GO:0019932 73 0.013
digestive system development GO:0055123 200 0.013
macromolecular complex disassembly GO:0032984 43 0.013
cation transmembrane transport GO:0098655 266 0.013
regulation of cell projection organization GO:0031344 206 0.013
connective tissue development GO:0061448 179 0.013
lateral line system development GO:0048925 1 0.013
negative regulation of kinase activity GO:0033673 81 0.013
fat cell differentiation GO:0045444 160 0.013
forebrain development GO:0030900 302 0.013
lung alveolus development GO:0048286 45 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
neuron apoptotic process GO:0051402 142 0.013
ossification GO:0001503 216 0.013
regulation of transporter activity GO:0032409 57 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
regulation of protein catabolic process GO:0042176 108 0.013
establishment of synaptic vesicle localization GO:0097480 57 0.013
bone morphogenesis GO:0060349 78 0.013
eye photoreceptor cell differentiation GO:0001754 41 0.013
rhythmic process GO:0048511 174 0.013
response to oxidative stress GO:0006979 123 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
nuclear division GO:0000280 158 0.013
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.012
regulation of chromosome organization GO:0033044 83 0.012
microtubule based transport GO:0010970 50 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
internal peptidyl lysine acetylation GO:0018393 42 0.012
insulin receptor signaling pathway GO:0008286 49 0.012
macromolecule methylation GO:0043414 120 0.012
protein import GO:0017038 101 0.012
microtubule based movement GO:0007018 84 0.012
regulation of ion transport GO:0043269 215 0.012
synapse organization GO:0050808 125 0.012
nucleotide catabolic process GO:0009166 217 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
multi multicellular organism process GO:0044706 109 0.012
neurotransmitter transport GO:0006836 76 0.012
protein acylation GO:0043543 64 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
meiotic nuclear division GO:0007126 115 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of receptor activity GO:0010469 41 0.012
cellular response to oxidative stress GO:0034599 76 0.012
neuronal action potential GO:0019228 54 0.012
mesodermal cell migration GO:0008078 4 0.012
regulation of jun kinase activity GO:0043506 40 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
innate immune response GO:0045087 157 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
regulation of endocytosis GO:0030100 69 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
Human
retina development in camera type eye GO:0060041 119 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
regulation of membrane potential GO:0042391 192 0.012
adult behavior GO:0030534 135 0.012
negative regulation of neuron death GO:1901215 98 0.011
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.011
learning GO:0007612 98 0.011
gonad development GO:0008406 141 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
skeletal muscle organ development GO:0060538 163 0.011
mitotic cytokinesis GO:0000281 4 0.011
regulation of neurological system process GO:0031644 22 0.011
cardiac muscle contraction GO:0060048 32 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
cation homeostasis GO:0055080 212 0.011
neurotransmitter secretion GO:0007269 62 0.011
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.011
regulation of protein stability GO:0031647 52 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of cell size GO:0008361 72 0.011
striated muscle cell development GO:0055002 125 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
blastocyst development GO:0001824 80 0.011
ear development GO:0043583 200 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
erythrocyte differentiation GO:0030218 88 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
negative regulation of immune system process GO:0002683 209 0.011
muscle system process GO:0003012 141 0.011
cytokine production GO:0001816 319 0.011
negative regulation of cell development GO:0010721 169 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
ribonucleoprotein complex disassembly GO:0032988 3 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
response to extracellular stimulus GO:0009991 127 0.011
nucleoside catabolic process GO:0009164 206 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
Human
retina morphogenesis in camera type eye GO:0060042 45 0.011
respiratory tube development GO:0030323 167 0.010
response to pain GO:0048265 26 0.010
protein alkylation GO:0008213 81 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
multicellular organismal signaling GO:0035637 91 0.010
cellular protein complex assembly GO:0043623 116 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
receptor mediated endocytosis GO:0006898 51 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
monosaccharide biosynthetic process GO:0046364 44 0.010
negative regulation of organelle organization GO:0010639 90 0.010
glucose metabolic process GO:0006006 92 0.010
histone h4 k16 acetylation GO:0043984 3 0.010
response to inorganic substance GO:0010035 96 0.010
regulation of insulin receptor signaling pathway GO:0046626 21 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
mrna splicing via spliceosome GO:0000398 43 0.010
regulation of triglyceride biosynthetic process GO:0010866 10 0.010
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.010

Ube2o disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
neuromuscular disease DOID:440 0 0.013
neuropathy DOID:870 0 0.013
immune system disease DOID:2914 0 0.010
hematopoietic system disease DOID:74 0 0.010