Mus musculus

37 known processes

Ube2a

ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae)

(Aliases: HHR6A,HR6A,Mhr6a)

Ube2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle catabolic process GO:0046700 280 0.149
Yeast
ribose phosphate metabolic process GO:0019693 291 0.129
Yeast
nucleoside phosphate metabolic process GO:0006753 338 0.127
Yeast
purine nucleotide catabolic process GO:0006195 211 0.118
Yeast
ribonucleoside metabolic process GO:0009119 245 0.113
Yeast
purine containing compound catabolic process GO:0072523 213 0.109
Yeast
organic cyclic compound catabolic process GO:1901361 295 0.103
Yeast
glycosyl compound catabolic process GO:1901658 206 0.099
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.094
Yeast
cellular protein catabolic process GO:0044257 155 0.089
Yeast Fly
nucleoside metabolic process GO:0009116 246 0.086
Yeast
nucleotide metabolic process GO:0009117 332 0.082
Yeast
exocytosis GO:0006887 121 0.078
organonitrogen compound catabolic process GO:1901565 264 0.074
Yeast
protein catabolic process GO:0030163 221 0.073
Yeast Fly
macromolecule catabolic process GO:0009057 281 0.072
Yeast Fly
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
Yeast
nucleoside phosphate catabolic process GO:1901292 222 0.066
Yeast
purine nucleoside catabolic process GO:0006152 205 0.066
Yeast
ribonucleotide metabolic process GO:0009259 291 0.065
Yeast
purine ribonucleotide catabolic process GO:0009154 208 0.064
Yeast
purine ribonucleotide metabolic process GO:0009150 290 0.063
Yeast
ribonucleotide catabolic process GO:0009261 208 0.061
Yeast
guanosine containing compound metabolic process GO:1901068 144 0.058
aromatic compound catabolic process GO:0019439 286 0.057
Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.055
Yeast
purine ribonucleoside metabolic process GO:0046128 241 0.054
Yeast
regulation of secretion by cell GO:1903530 249 0.053
protein modification by small protein conjugation GO:0032446 187 0.052
purine nucleotide metabolic process GO:0006163 302 0.052
Yeast
regulation of cellular catabolic process GO:0031329 242 0.051
Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.051
Yeast
retrograde transport endosome to golgi GO:0042147 2 0.051
carbohydrate derivative catabolic process GO:1901136 231 0.050
Yeast
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.048
microtubule based process GO:0007017 236 0.048
Mouse Fly
cellular nitrogen compound catabolic process GO:0044270 280 0.046
Yeast
guanosine containing compound catabolic process GO:1901069 144 0.045
regulation of secretion GO:0051046 274 0.045
purine nucleoside triphosphate catabolic process GO:0009146 203 0.044
Yeast
purine containing compound metabolic process GO:0072521 311 0.043
Yeast
cellular amine metabolic process GO:0044106 44 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.043
Yeast
synaptic transmission GO:0007268 329 0.043
protein neddylation GO:0045116 1 0.042
negative regulation of cellular component organization GO:0051129 194 0.041
Mouse
regulation of cell projection organization GO:0031344 206 0.040
nucleoside triphosphate catabolic process GO:0009143 205 0.040
Yeast
regulation of protein transport GO:0051223 163 0.040
gtp catabolic process GO:0006184 143 0.039
gtp metabolic process GO:0046039 144 0.039
cellular macromolecule catabolic process GO:0044265 206 0.038
Yeast Fly
regulation of organelle organization GO:0033043 289 0.038
Mouse
glycosyl compound metabolic process GO:1901657 246 0.038
Yeast
nitrogen compound transport GO:0071705 271 0.038
Yeast
regulation of cell migration GO:0030334 219 0.037
regulation of neuron differentiation GO:0045664 281 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.036
Yeast
amine metabolic process GO:0009308 45 0.036
positive regulation of cell projection organization GO:0031346 95 0.036
stem cell development GO:0048864 219 0.035
nucleoside catabolic process GO:0009164 206 0.034
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.034
Yeast Fly
amide transport GO:0042886 138 0.033
Yeast
cellular amino acid metabolic process GO:0006520 103 0.033
regulation of protein catabolic process GO:0042176 108 0.033
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
positive regulation of secretion GO:0051047 130 0.032
canonical wnt signaling pathway GO:0060070 130 0.032
Mouse
peptide transport GO:0015833 133 0.031
Yeast
positive regulation of protein modification process GO:0031401 299 0.031
cation transport GO:0006812 399 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
Yeast
maintenance of location GO:0051235 89 0.029
endomembrane system organization GO:0010256 147 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
positive regulation of apoptotic process GO:0043065 217 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
regulation of intracellular transport GO:0032386 159 0.028
nucleotide catabolic process GO:0009166 217 0.028
Yeast
purine nucleoside metabolic process GO:0042278 241 0.027
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
Yeast
regulation of protein localization GO:0032880 231 0.027
positive regulation of secretion by cell GO:1903532 114 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.025
hormone secretion GO:0046879 128 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
cytoplasmic transport GO:0016482 234 0.025
negative regulation of synapse assembly GO:0051964 3 0.025
wnt signaling pathway GO:0016055 188 0.024
Mouse
mapk cascade GO:0000165 281 0.024
apoptotic signaling pathway GO:0097190 306 0.024
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.023
positive regulation of cell development GO:0010720 237 0.023
regulation of anatomical structure size GO:0090066 178 0.023
regulation of nucleotide catabolic process GO:0030811 122 0.023
mitotic cell cycle GO:0000278 195 0.023
Yeast Fly
microtubule cytoskeleton organization GO:0000226 157 0.023
Mouse Fly
regulation of cytoplasmic transport GO:1903649 112 0.022
positive regulation of cell death GO:0010942 224 0.022
regulation of neuron projection development GO:0010975 169 0.021
negative regulation of nervous system development GO:0051961 156 0.021
cellular chemical homeostasis GO:0055082 215 0.021
stem cell differentiation GO:0048863 268 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
establishment of melanosome localization GO:0032401 11 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
dna metabolic process GO:0006259 303 0.020
Human Yeast Mouse Worm Fly
cellular ketone metabolic process GO:0042180 84 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
striated muscle tissue development GO:0014706 293 0.020
organophosphate catabolic process GO:0046434 232 0.020
Yeast
peptide secretion GO:0002790 114 0.020
regulation of establishment of protein localization GO:0070201 181 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
compound eye development GO:0048749 1 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
Yeast
response to light stimulus GO:0009416 135 0.019
Human
regulation of cell cycle GO:0051726 281 0.019
Yeast Mouse
regulation of cell motility GO:2000145 236 0.019
protein localization to organelle GO:0033365 185 0.019
insulin secretion GO:0030073 89 0.019
regulation of kinase activity GO:0043549 249 0.019
peptide hormone secretion GO:0030072 109 0.019
negative regulation of protein metabolic process GO:0051248 282 0.018
Mouse
organelle localization GO:0051640 179 0.018
negative regulation of cell development GO:0010721 169 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of intracellular protein transport GO:0033157 82 0.018
positive regulation of nervous system development GO:0051962 221 0.017
trivalent inorganic cation transport GO:0072512 5 0.017
regulation of mapk cascade GO:0043408 248 0.017
modification dependent protein catabolic process GO:0019941 133 0.016
Yeast Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.016
Mouse
ras protein signal transduction GO:0007265 77 0.016
regulation of hydrolase activity GO:0051336 246 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
exosomal secretion GO:1990182 1 0.015
regulation of cell growth GO:0001558 91 0.015
male gamete generation GO:0048232 285 0.015
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of hormone levels GO:0010817 211 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.015
virion assembly GO:0019068 1 0.015
positive regulation of programmed cell death GO:0043068 218 0.014
cell growth GO:0016049 130 0.014
sequestering of metal ion GO:0051238 19 0.014
transmembrane transport GO:0055085 412 0.014
regulation of multi organism process GO:0043900 111 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
Fly
cellular response to carbohydrate stimulus GO:0071322 50 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
chromatin organization GO:0006325 206 0.014
Human Yeast Mouse
positive regulation of neuron differentiation GO:0045666 141 0.014
carbohydrate homeostasis GO:0033500 128 0.014
ion transmembrane transport GO:0034220 361 0.014
regulation of cellular component size GO:0032535 121 0.014
glucose homeostasis GO:0042593 128 0.014
membrane organization GO:0061024 245 0.014
cellular glucose homeostasis GO:0001678 52 0.014
positive regulation of hydrolase activity GO:0051345 148 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
protein ubiquitination GO:0016567 171 0.013
response to organonitrogen compound GO:0010243 246 0.013
chromatin modification GO:0016568 187 0.013
Human Yeast Mouse
muscle tissue development GO:0060537 308 0.013
localization within membrane GO:0051668 4 0.013
cell adhesion GO:0007155 329 0.013
regulation of protein kinase activity GO:0045859 232 0.013
positive regulation of proteolysis GO:0045862 85 0.013
Fly
spermatogenesis GO:0007283 284 0.013
Mouse
cytokine production GO:0001816 319 0.012
positive regulation of cell motility GO:2000147 116 0.012
protein import GO:0017038 101 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
Fly
stress activated protein kinase signaling cascade GO:0031098 81 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
regulation of cell size GO:0008361 72 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
protein import into nucleus GO:0006606 95 0.012
sequestering of calcium ion GO:0051208 18 0.012
viral process GO:0016032 41 0.012
cellular homeostasis GO:0019725 240 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
positive regulation of cell migration GO:0030335 109 0.011
divalent inorganic cation transport GO:0072511 178 0.011
lateral inhibition GO:0046331 1 0.011
early endosome to late endosome transport GO:0045022 2 0.011
establishment of organelle localization GO:0051656 122 0.011
divalent metal ion transport GO:0070838 172 0.011
vesicle localization GO:0051648 86 0.011
regulation of axon extension GO:0030516 43 0.011
peptidyl amino acid modification GO:0018193 336 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
response to starvation GO:0042594 65 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
protein secretion GO:0009306 111 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
Mouse
respiratory system development GO:0060541 190 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
Yeast Fly
positive regulation of protein transport GO:0051222 93 0.011
response to growth factor GO:0070848 198 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
cell junction maintenance GO:0034331 4 0.011
endocytosis GO:0006897 168 0.011
negative regulation of protein modification process GO:0031400 163 0.011
Mouse
formation of organ boundary GO:0010160 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
regulation of canonical wnt signaling pathway GO:0060828 82 0.011
cellular protein complex assembly GO:0043623 116 0.011
positive regulation of transferase activity GO:0051347 167 0.011
interspecies interaction between organisms GO:0044419 83 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
Fly
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
gland development GO:0048732 330 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
Yeast Fly
erk1 and erk2 cascade GO:0070371 77 0.010
developmental cell growth GO:0048588 84 0.010
cation transmembrane transport GO:0098655 266 0.010
histone modification GO:0016570 159 0.010
Human Yeast Mouse
positive regulation of kinase activity GO:0033674 155 0.010
regulation of embryonic development GO:0045995 71 0.010
protein targeting GO:0006605 143 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010

Ube2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
eye and adnexa disease DOID:1492 0 0.010
nervous system disease DOID:863 0 0.010
eye disease DOID:5614 0 0.010
sensory system disease DOID:0050155 0 0.010
disease of anatomical entity DOID:7 0 0.010