Mus musculus

227 known processes

Ube2b

ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae)

(Aliases: Rad6b,mHR6B,2610301N02Rik,HR6B,E2-14k)

Ube2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein localization to peroxisome GO:0072662 4 0.124
protein targeting to peroxisome GO:0006625 4 0.096
translation GO:0006412 93 0.084
germ cell development GO:0007281 185 0.080
membrane organization GO:0061024 245 0.073
translational initiation GO:0006413 24 0.069
cellular response to dna damage stimulus GO:0006974 207 0.062
Human Yeast Worm Fly
establishment of protein localization to peroxisome GO:0072663 4 0.060
nucleotide metabolic process GO:0009117 332 0.055
Yeast
modification dependent protein catabolic process GO:0019941 133 0.054
Human Yeast Rat Fly
proteasomal protein catabolic process GO:0010498 98 0.051
Human Yeast Fly
cytoplasmic transport GO:0016482 234 0.047
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.046
cellular protein catabolic process GO:0044257 155 0.045
Human Yeast Rat Fly
organelle fission GO:0048285 170 0.045
negative regulation of cellular protein metabolic process GO:0032269 247 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.042
Yeast
cellular macromolecule catabolic process GO:0044265 206 0.042
Human Yeast Rat Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.042
regulation of long term synaptic potentiation GO:1900271 4 0.040
peroxisomal transport GO:0043574 4 0.040
synaptic transmission GO:0007268 329 0.040
purine ribonucleotide catabolic process GO:0009154 208 0.039
Yeast
male gamete generation GO:0048232 285 0.039
cellular ketone metabolic process GO:0042180 84 0.038
protein catabolic process GO:0030163 221 0.038
Human Yeast Rat Fly
transmembrane transport GO:0055085 412 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
Fly
pyruvate transport GO:0006848 2 0.034
lipid localization GO:0010876 126 0.034
protein ubiquitination GO:0016567 171 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
Yeast
centrosome organization GO:0051297 26 0.030
Fly
cellular amino acid metabolic process GO:0006520 103 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
Rat
small gtpase mediated signal transduction GO:0007264 97 0.028
intracellular protein transport GO:0006886 204 0.027
macromolecule catabolic process GO:0009057 281 0.027
Human Yeast Rat Fly
spermatogenesis GO:0007283 284 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
spermatid differentiation GO:0048515 115 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
Human Yeast Rat Fly
regulation of synaptic plasticity GO:0048167 87 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
stem cell differentiation GO:0048863 268 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
Yeast
negative regulation of cellular component organization GO:0051129 194 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.024
Human Yeast Fly
mitochondrion organization GO:0007005 134 0.024
regulation of establishment of protein localization GO:0070201 181 0.024
amine metabolic process GO:0009308 45 0.023
protein localization to organelle GO:0033365 185 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
Yeast
stem cell development GO:0048864 219 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
Human
cellular amine metabolic process GO:0044106 44 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
Yeast
peptidyl tyrosine modification GO:0018212 145 0.021
divalent metal ion transport GO:0070838 172 0.021
oxidation reduction process GO:0055114 342 0.021
mitochondrion distribution GO:0048311 4 0.020
regulation of rna splicing GO:0043484 37 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.019
Yeast
transcription from rna polymerase iii promoter GO:0006383 3 0.019
cellular homeostasis GO:0019725 240 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
Yeast
endocytosis GO:0006897 168 0.019
regulation of intracellular transport GO:0032386 159 0.019
microtubule organizing center organization GO:0031023 28 0.019
Fly
golgi to endosome transport GO:0006895 3 0.018
cognition GO:0050890 149 0.018
maintenance of location GO:0051235 89 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
mitochondrial transport GO:0006839 36 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
peptidyl amino acid modification GO:0018193 336 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
Yeast
circadian regulation of gene expression GO:0032922 48 0.018
fertilization GO:0009566 127 0.018
long term synaptic potentiation GO:0060291 25 0.017
response to acid chemical GO:0001101 111 0.017
response to peptide hormone GO:0043434 127 0.017
Rat
ribose phosphate metabolic process GO:0019693 291 0.017
Yeast
cellular response to cytokine stimulus GO:0071345 189 0.017
purine containing compound metabolic process GO:0072521 311 0.017
Yeast
lipoprotein metabolic process GO:0042157 43 0.017
male genitalia morphogenesis GO:0048808 4 0.017
endomembrane system organization GO:0010256 147 0.017
wnt signaling pathway GO:0016055 188 0.017
learning or memory GO:0007611 148 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
Rat
organic acid biosynthetic process GO:0016053 86 0.017
dna metabolic process GO:0006259 303 0.017
homeostasis of number of cells GO:0048872 210 0.017
negative regulation of translational initiation GO:0045947 4 0.017
cytokine mediated signaling pathway GO:0019221 115 0.016
fat cell differentiation GO:0045444 160 0.016
divalent inorganic cation transport GO:0072511 178 0.016
glucose homeostasis GO:0042593 128 0.016
muscle tissue development GO:0060537 308 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
Fly
positive regulation of programmed cell death GO:0043068 218 0.016
negative regulation of immune system process GO:0002683 209 0.016
lipoprotein biosynthetic process GO:0042158 33 0.016
response to organonitrogen compound GO:0010243 246 0.016
Rat
regulation of lymphocyte activation GO:0051249 240 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
regulation of cellular response to stress GO:0080135 159 0.016
Fly
regulation of carbohydrate metabolic process GO:0006109 75 0.016
organic acid transport GO:0015849 101 0.015
regulation of secretion GO:0051046 274 0.015
anion transport GO:0006820 177 0.015
rhythmic process GO:0048511 174 0.015
myeloid cell differentiation GO:0030099 233 0.015
protein lipidation GO:0006497 28 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
Human Fly
purine ribonucleoside metabolic process GO:0046128 241 0.015
Yeast
mapk cascade GO:0000165 281 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
female gamete generation GO:0007292 74 0.015
cation transport GO:0006812 399 0.014
cellular chemical homeostasis GO:0055082 215 0.014
purine containing compound catabolic process GO:0072523 213 0.014
Yeast
autophagy GO:0006914 45 0.014
Fly
guanosine containing compound catabolic process GO:1901069 144 0.014
cellular response to lipid GO:0071396 145 0.014
negative regulation of nervous system development GO:0051961 156 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.014
heterocycle catabolic process GO:0046700 280 0.014
Yeast
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
chiasma assembly GO:0051026 6 0.014
negative regulation of cell development GO:0010721 169 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
phosphatidylinositol mediated signaling GO:0048015 41 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
stem cell maintenance GO:0019827 130 0.013
regulation of membrane potential GO:0042391 192 0.013
regulation of transmembrane transport GO:0034762 128 0.013
methylation GO:0032259 134 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
regulation of cell migration GO:0030334 219 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
nuclear division GO:0000280 158 0.013
response to organic cyclic compound GO:0014070 198 0.013
dna recombination GO:0006310 92 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
regulation of protein transport GO:0051223 163 0.013
mitotic cell cycle GO:0000278 195 0.013
Yeast Fly
regulation of cellular catabolic process GO:0031329 242 0.013
Fly
aromatic compound catabolic process GO:0019439 286 0.013
Yeast
multicellular organismal signaling GO:0035637 91 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
leukocyte differentiation GO:0002521 342 0.012
exocytosis GO:0006887 121 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cellular lipid metabolic process GO:0044255 323 0.012
apoptotic signaling pathway GO:0097190 306 0.012
Fly
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
regionalization GO:0003002 337 0.012
double strand break repair via homologous recombination GO:0000724 21 0.012
Yeast
early endosome to late endosome transport GO:0045022 2 0.012
positive regulation of secretion GO:0051047 130 0.012
nucleoside metabolic process GO:0009116 246 0.012
Yeast
cation transmembrane transport GO:0098655 266 0.012
dna repair GO:0006281 107 0.012
Human Yeast Worm Fly
organic anion transport GO:0015711 137 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
Human Yeast Rat Fly
rho protein signal transduction GO:0007266 32 0.011
regulation of proteolysis GO:0030162 164 0.011
Fly
striated muscle myosin thick filament assembly GO:0071688 1 0.011
memory GO:0007613 58 0.011
response to steroid hormone GO:0048545 56 0.011
regulation of secretion by cell GO:1903530 249 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
rna processing GO:0006396 105 0.011
mitotic cell cycle process GO:1903047 159 0.011
Yeast Fly
regulation of mapk cascade GO:0043408 248 0.011
blastocyst development GO:0001824 80 0.011
phospholipid metabolic process GO:0006644 87 0.011
vacuole organization GO:0007033 38 0.011
muscle system process GO:0003012 141 0.011
rab protein signal transduction GO:0032482 1 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
negative regulation of translation GO:0017148 22 0.011
regulation of protein localization GO:0032880 231 0.011
gluconeogenesis GO:0006094 39 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.010
Yeast
response to radiation GO:0009314 165 0.010
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.010
Yeast
vesicle organization GO:0016050 60 0.010
rna splicing GO:0008380 54 0.010
transmission of nerve impulse GO:0019226 76 0.010
localization within membrane GO:0051668 4 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
Yeast
sequestering of calcium ion GO:0051208 18 0.010
mrna splicing via spliceosome GO:0000398 43 0.010
macromolecule methylation GO:0043414 120 0.010
carboxylic acid transport GO:0046942 100 0.010
nucleoside catabolic process GO:0009164 206 0.010
Yeast

Ube2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
nervous system disease DOID:863 0 0.011
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011