Mus musculus

0 known processes

Brd1

bromodomain containing 1

(Aliases: mKIAA4191,AI316859,1110059H06Rik,KIAA4191,MGC164733)

Brd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 187 0.613
covalent chromatin modification GO:0016569 163 0.556
histone modification GO:0016570 159 0.347
protein modification by small protein conjugation or removal GO:0070647 207 0.248
chromatin organization GO:0006325 206 0.200
male gamete generation GO:0048232 285 0.176
protein ubiquitination GO:0016567 171 0.172
modification dependent macromolecule catabolic process GO:0043632 133 0.149
cellular response to dna damage stimulus GO:0006974 207 0.135
protein modification by small protein conjugation GO:0032446 187 0.128
myeloid cell differentiation GO:0030099 233 0.108
rhythmic process GO:0048511 174 0.091
macromolecule catabolic process GO:0009057 281 0.090
nuclear division GO:0000280 158 0.089
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.086
cellular ketone metabolic process GO:0042180 84 0.079
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.078
protein deacetylation GO:0006476 32 0.075
regulation of cellular amine metabolic process GO:0033238 20 0.074
regulation of histone modification GO:0031056 56 0.072
regulation of chromatin organization GO:1902275 57 0.071
regulation of cell cycle GO:0051726 281 0.071
cellular amine metabolic process GO:0044106 44 0.071
peptidyl lysine modification GO:0018205 77 0.070
protein polyubiquitination GO:0000209 33 0.069
histone methylation GO:0016571 71 0.068
protein deacylation GO:0035601 36 0.068
ossification GO:0001503 216 0.066
axonogenesis GO:0007409 274 0.064
regionalization GO:0003002 337 0.063
cellular macromolecule catabolic process GO:0044265 206 0.063
multicellular organism growth GO:0035264 161 0.063
ubiquitin dependent protein catabolic process GO:0006511 129 0.061
protein methylation GO:0006479 81 0.060
regulation of cellular ketone metabolic process GO:0010565 66 0.060
amine metabolic process GO:0009308 45 0.057
cellular protein catabolic process GO:0044257 155 0.054
posttranscriptional regulation of gene expression GO:0010608 155 0.051
striated muscle tissue development GO:0014706 293 0.051
cognition GO:0050890 149 0.051
negative regulation of cellular amine metabolic process GO:0033239 1 0.050
leukocyte differentiation GO:0002521 342 0.050
peptidyl amino acid modification GO:0018193 336 0.049
muscle tissue development GO:0060537 308 0.048
regulation of rho protein signal transduction GO:0035023 71 0.047
positive regulation of cell death GO:0010942 224 0.047
skeletal muscle cell differentiation GO:0035914 66 0.047
myeloid cell homeostasis GO:0002262 114 0.046
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.046
regulation of ossification GO:0030278 112 0.046
regulation of organelle organization GO:0033043 289 0.046
negative regulation of molecular function GO:0044092 258 0.045
regulation of cellular response to stress GO:0080135 159 0.045
respiratory tube development GO:0030323 167 0.044
Mouse
cytoplasmic transport GO:0016482 234 0.044
methylation GO:0032259 134 0.043
germ cell development GO:0007281 185 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
dna metabolic process GO:0006259 303 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
negative regulation of immune system process GO:0002683 209 0.042
positive regulation of apoptotic process GO:0043065 217 0.041
signal transduction by p53 class mediator GO:0072331 51 0.041
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.041
negative regulation of intracellular signal transduction GO:1902532 167 0.040
histone acetylation GO:0016573 41 0.040
spermatogenesis GO:0007283 284 0.040
positive regulation of organelle organization GO:0010638 128 0.039
heart morphogenesis GO:0003007 178 0.038
skeletal system morphogenesis GO:0048705 203 0.038
neural precursor cell proliferation GO:0061351 121 0.037
protein acylation GO:0043543 64 0.037
face development GO:0060324 38 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.036
skeletal muscle organ development GO:0060538 163 0.036
erythrocyte differentiation GO:0030218 88 0.036
meiosis i GO:0007127 60 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
histone deacetylation GO:0016575 26 0.034
learning or memory GO:0007611 148 0.034
sensory organ morphogenesis GO:0090596 242 0.034
gene silencing GO:0016458 38 0.033
dna repair GO:0006281 107 0.033
cell adhesion GO:0007155 329 0.033
regulation of neuron projection development GO:0010975 169 0.033
compound eye development GO:0048749 1 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
Mouse
apoptotic signaling pathway GO:0097190 306 0.032
negative regulation of growth GO:0045926 99 0.031
regulation of chromosome organization GO:0033044 83 0.031
olfactory learning GO:0008355 2 0.031
response to radiation GO:0009314 165 0.030
oocyte axis specification GO:0007309 2 0.030
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.030
embryonic organ morphogenesis GO:0048562 276 0.030
protein catabolic process GO:0030163 221 0.030
macromolecule deacylation GO:0098732 37 0.030
negative regulation of protein metabolic process GO:0051248 282 0.029
mrna processing GO:0006397 63 0.029
response to oxidative stress GO:0006979 123 0.029
positive regulation of dna templated transcription elongation GO:0032786 2 0.029
epithelial cell development GO:0002064 159 0.029
lymphocyte differentiation GO:0030098 242 0.028
modification dependent protein catabolic process GO:0019941 133 0.028
head morphogenesis GO:0060323 34 0.028
mitotic cell cycle process GO:1903047 159 0.028
purine nucleotide metabolic process GO:0006163 302 0.027
regulation of stem cell differentiation GO:2000736 50 0.027
face morphogenesis GO:0060325 29 0.027
homeostasis of number of cells GO:0048872 210 0.027
negative regulation of cell cycle GO:0045786 123 0.027
morphogenesis of embryonic epithelium GO:0016331 159 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
regulation of cell projection organization GO:0031344 206 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
camera type eye development GO:0043010 266 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.026
Mouse
gland development GO:0048732 330 0.026
regulation of chromatin modification GO:1903308 57 0.026
stem cell differentiation GO:0048863 268 0.026
skeletal system development GO:0001501 356 0.026
organelle localization GO:0051640 179 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
mitotic chromosome condensation GO:0007076 1 0.025
negative regulation of nervous system development GO:0051961 156 0.025
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.025
rho protein signal transduction GO:0007266 32 0.025
embryonic limb morphogenesis GO:0030326 126 0.025
limb morphogenesis GO:0035108 149 0.025
regulation of cellular component biogenesis GO:0044087 181 0.024
regulation of myeloid cell differentiation GO:0045637 96 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
Mouse
oocyte construction GO:0007308 2 0.024
myeloid leukocyte differentiation GO:0002573 119 0.024
spermatid differentiation GO:0048515 115 0.024
synaptic transmission GO:0007268 329 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.024
circadian regulation of gene expression GO:0032922 48 0.024
lung development GO:0030324 164 0.024
Mouse
mrna splicing via spliceosome GO:0000398 43 0.023
translation GO:0006412 93 0.023
negative regulation of protein modification process GO:0031400 163 0.023
chromatin assembly or disassembly GO:0006333 16 0.023
regulation of myeloid leukocyte differentiation GO:0002761 58 0.023
microtubule cytoskeleton organization GO:0000226 157 0.023
hepaticobiliary system development GO:0061008 67 0.022
digestive system development GO:0055123 200 0.022
organelle fission GO:0048285 170 0.022
rna interference GO:0016246 2 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
histone h4 deacetylation GO:0070933 4 0.022
stem cell development GO:0048864 219 0.022
peptidyl lysine acetylation GO:0018394 45 0.022
positive regulation of wnt signaling pathway GO:0030177 45 0.021
dendrite development GO:0016358 115 0.021
tube formation GO:0035148 140 0.021
regulation of mapk cascade GO:0043408 248 0.021
development of primary male sexual characteristics GO:0046546 88 0.021
blood vessel morphogenesis GO:0048514 285 0.021
dna packaging GO:0006323 30 0.021
mitotic cell cycle GO:0000278 195 0.021
ovulation cycle GO:0042698 59 0.021
b cell activation GO:0042113 161 0.021
mitochondrion distribution GO:0048311 4 0.021
regulation of response to dna damage stimulus GO:2001020 34 0.021
t cell activation GO:0042110 289 0.021
regulation of system process GO:0044057 200 0.021
single organism cell adhesion GO:0098602 156 0.021
regulation of osteoblast differentiation GO:0045667 67 0.021
gonad development GO:0008406 141 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
dna conformation change GO:0071103 37 0.020
nuclear transport GO:0051169 139 0.020
mitotic sister chromatid segregation GO:0000070 14 0.020
fat cell differentiation GO:0045444 160 0.020
spermatid development GO:0007286 108 0.020
histone lysine methylation GO:0034968 50 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
digestive tract morphogenesis GO:0048546 147 0.020
negative regulation of ossification GO:0030279 49 0.020
internal protein amino acid acetylation GO:0006475 42 0.020
regulation of protein complex assembly GO:0043254 83 0.020
canonical wnt signaling pathway GO:0060070 130 0.019
learning GO:0007612 98 0.019
extracellular matrix organization GO:0030198 147 0.019
t cell differentiation GO:0030217 174 0.019
extracellular structure organization GO:0043062 148 0.019
developmental maturation GO:0021700 193 0.019
epithelial cell morphogenesis GO:0003382 41 0.019
bmp signaling pathway GO:0030509 93 0.019
fertilization GO:0009566 127 0.019
limb development GO:0060173 166 0.019
regulation of cell activation GO:0050865 289 0.019
digestive tract development GO:0048565 190 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
proteasomal protein catabolic process GO:0010498 98 0.018
regulation of hydrolase activity GO:0051336 246 0.018
neuron projection guidance GO:0097485 141 0.018
macromolecule methylation GO:0043414 120 0.018
t cell proliferation GO:0042098 120 0.018
oogenesis GO:0048477 56 0.018
megakaryocyte differentiation GO:0030219 26 0.018
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
regulation of circadian rhythm GO:0042752 58 0.018
sister chromatid segregation GO:0000819 20 0.018
germ line stem cell division GO:0042078 2 0.018
lymphocyte proliferation GO:0046651 164 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
protein alkylation GO:0008213 81 0.017
establishment or maintenance of cell polarity GO:0007163 86 0.017
regulation of cellular component size GO:0032535 121 0.017
localization within membrane GO:0051668 4 0.017
protein localization to nucleus GO:0034504 121 0.017
regulation of neuron differentiation GO:0045664 281 0.017
mapk cascade GO:0000165 281 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
embryonic placenta development GO:0001892 98 0.017
placenta development GO:0001890 140 0.017
epithelial cell proliferation GO:0050673 174 0.017
male sex differentiation GO:0046661 109 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
lateral inhibition GO:0046331 1 0.017
regulation of cell cycle process GO:0010564 160 0.017
circadian rhythm GO:0007623 114 0.017
response to lipopolysaccharide GO:0032496 128 0.017
epithelial tube formation GO:0072175 130 0.017
negative regulation of myeloid cell differentiation GO:0045638 38 0.017
cell proliferation involved in heart valve development GO:2000793 2 0.017
regulation of chromatin silencing GO:0031935 2 0.017
regulation of ras protein signal transduction GO:0046578 114 0.017
regulation of embryonic development GO:0045995 71 0.017
regulation of t cell activation GO:0050863 170 0.016
actin cytoskeleton organization GO:0030036 220 0.016
negative regulation of osteoblast differentiation GO:0045668 30 0.016
cardiac chamber development GO:0003205 108 0.016
transdifferentiation GO:0060290 1 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
stem cell maintenance GO:0019827 130 0.016
chromatin silencing at rdna GO:0000183 3 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
response to light stimulus GO:0009416 135 0.016
intracellular distribution of mitochondria GO:0048312 1 0.016
aromatic compound catabolic process GO:0019439 286 0.016
regulation of cytokine production GO:0001817 266 0.015
response to growth factor GO:0070848 198 0.015
regulation of kinase activity GO:0043549 249 0.015
smad protein signal transduction GO:0060395 21 0.015
Mouse
negative regulation of chromatin silencing GO:0031936 1 0.015
female gamete generation GO:0007292 74 0.015
jak stat cascade GO:0007259 42 0.015
leukocyte proliferation GO:0070661 172 0.015
cellular protein complex assembly GO:0043623 116 0.015
habituation GO:0046959 3 0.015
organophosphate catabolic process GO:0046434 232 0.015
anatomical structure homeostasis GO:0060249 145 0.015
rna processing GO:0006396 105 0.015
cation transport GO:0006812 399 0.015
aortic valve morphogenesis GO:0003180 4 0.015
ribonucleotide catabolic process GO:0009261 208 0.014
locomotory behavior GO:0007626 195 0.014
leukocyte mediated immunity GO:0002443 174 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
ovarian follicle development GO:0001541 40 0.014
mrna 3 end processing GO:0031124 16 0.014
ras protein signal transduction GO:0007265 77 0.014
chromatin silencing GO:0006342 15 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
divalent inorganic cation transport GO:0072511 178 0.014
negative regulation of organelle organization GO:0010639 90 0.014
palate development GO:0060021 76 0.014
heterocycle catabolic process GO:0046700 280 0.014
nitrogen compound transport GO:0071705 271 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
chemotaxis GO:0006935 247 0.014
microtubule based process GO:0007017 236 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
maintenance of location GO:0051235 89 0.014
nucleotide metabolic process GO:0009117 332 0.014
intracellular receptor signaling pathway GO:0030522 74 0.014
ear morphogenesis GO:0042471 118 0.014
lung cell differentiation GO:0060479 30 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
cellular response to lipid GO:0071396 145 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
immune effector process GO:0002252 321 0.013
mrna metabolic process GO:0016071 84 0.013
positive regulation of nervous system development GO:0051962 221 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
cytokine production GO:0001816 319 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
liver development GO:0001889 66 0.013
intracellular protein transport GO:0006886 204 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
neural crest cell differentiation GO:0014033 54 0.013
carbohydrate homeostasis GO:0033500 128 0.013
artery development GO:0060840 53 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
asymmetric stem cell division GO:0098722 3 0.013
regulation of neural precursor cell proliferation GO:2000177 70 0.013
somatic stem cell maintenance GO:0035019 47 0.013
regulation of synaptic plasticity GO:0048167 87 0.013
negative regulation of inflammatory response GO:0050728 61 0.012
internal peptidyl lysine acetylation GO:0018393 42 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
negative regulation of t cell proliferation GO:0042130 38 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
cytokine metabolic process GO:0042107 71 0.012
regulation of peptidyl lysine acetylation GO:2000756 22 0.012
transmembrane transport GO:0055085 412 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.012
chromatin assembly GO:0031497 13 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of inflammatory response GO:0050727 147 0.012
posttranscriptional gene silencing GO:0016441 10 0.012
actin filament polymerization GO:0030041 44 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
appendage development GO:0048736 166 0.012
cell type specific apoptotic process GO:0097285 268 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
mitochondrion organization GO:0007005 134 0.012
respiratory system development GO:0060541 190 0.012
Mouse
mesenchyme development GO:0060485 152 0.012
activation of immune response GO:0002253 138 0.012
negative regulation of translation GO:0017148 22 0.012
regulation of mrna metabolic process GO:1903311 43 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
embryonic skeletal system morphogenesis GO:0048704 91 0.011
nucleoside catabolic process GO:0009164 206 0.011
negative regulation of chromatin modification GO:1903309 19 0.011
positive regulation of ossification GO:0045778 47 0.011
positive regulation of myeloid cell differentiation GO:0045639 43 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
axon guidance GO:0007411 141 0.011
double strand break repair GO:0006302 48 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
positive regulation of chromosome organization GO:2001252 33 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of extent of cell growth GO:0061387 52 0.011
associative learning GO:0008306 61 0.011
regulation of viral transcription GO:0046782 3 0.011
negative regulation of mitotic cell cycle GO:0045930 58 0.011
bone mineralization GO:0030282 54 0.011
wnt signaling pathway GO:0016055 188 0.011
positive regulation of megakaryocyte differentiation GO:0045654 4 0.011
positive regulation of histone modification GO:0031058 28 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
positive regulation of cell development GO:0010720 237 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.011
establishment of mitochondrion localization GO:0051654 4 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
embryonic skeletal system development GO:0048706 120 0.011
positive regulation of protein modification process GO:0031401 299 0.011
negative regulation of wnt signaling pathway GO:0030178 73 0.011
bone morphogenesis GO:0060349 78 0.011
regulation of defense response GO:0031347 233 0.011
neural tube formation GO:0001841 108 0.011
definitive hemopoiesis GO:0060216 20 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
response to transforming growth factor beta GO:0071559 88 0.011
organ growth GO:0035265 117 0.011
actin filament based movement GO:0030048 23 0.011
dendritic spine development GO:0060996 30 0.011
embryonic eye morphogenesis GO:0048048 29 0.011
cell growth GO:0016049 130 0.010
regulation of secretion GO:0051046 274 0.010
neural tube development GO:0021915 160 0.010
negative regulation of bmp signaling pathway GO:0030514 35 0.010
male meiosis i GO:0007141 16 0.010
cardiac chamber morphogenesis GO:0003206 93 0.010
labyrinthine layer development GO:0060711 49 0.010
organelle assembly GO:0070925 177 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
stress activated mapk cascade GO:0051403 80 0.010
cell cycle switching GO:0060184 1 0.010
endodermal cell fate specification GO:0001714 4 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of transporter activity GO:0032409 57 0.010
cell fate commitment GO:0045165 210 0.010
cajal body organization GO:0030576 1 0.010
negative regulation of lymphocyte proliferation GO:0050672 45 0.010
purine containing compound metabolic process GO:0072521 311 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
gtp metabolic process GO:0046039 144 0.010
interspecies interaction between organisms GO:0044419 83 0.010
tissue homeostasis GO:0001894 115 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
morphogenesis of a polarized epithelium GO:0001738 37 0.010

Brd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
central nervous system disease DOID:331 0 0.015