Mus musculus

64 known processes

Tbpl2

TATA box binding protein like 2

(Aliases: Gm348,Trf3)

Tbpl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetylcholine secretion neurotransmission GO:0014055 2 0.459
acetate ester transport GO:1901374 2 0.217
acetylcholine transport GO:0015870 2 0.193
myosin filament assembly GO:0031034 2 0.189
multicellular organism growth GO:0035264 161 0.154
oxidation reduction process GO:0055114 342 0.121
myosin filament organization GO:0031033 3 0.106
cellular lipid metabolic process GO:0044255 323 0.106
multi multicellular organism process GO:0044706 109 0.099
striated muscle myosin thick filament assembly GO:0071688 1 0.096
defecation GO:0030421 1 0.087
fatty acid biosynthetic process GO:0006633 41 0.085
gland development GO:0048732 330 0.083
innate immune response GO:0045087 157 0.082
lipid biosynthetic process GO:0008610 179 0.080
organic hydroxy compound transport GO:0015850 93 0.080
organelle assembly GO:0070925 177 0.076
Mouse
organic acid biosynthetic process GO:0016053 86 0.074
muscle system process GO:0003012 141 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.066
regulation of defense response GO:0031347 233 0.060
small molecule biosynthetic process GO:0044283 132 0.059
regulation of innate immune response GO:0045088 91 0.058
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.057
carboxylic acid biosynthetic process GO:0046394 86 0.057
monocarboxylic acid biosynthetic process GO:0072330 61 0.055
unsaturated fatty acid metabolic process GO:0033559 31 0.051
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.049
muscle contraction GO:0006936 101 0.048
muscle cell development GO:0055001 133 0.044
feeding behavior GO:0007631 62 0.044
macromolecule catabolic process GO:0009057 281 0.043
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.042
cellular amine metabolic process GO:0044106 44 0.041
spermatogenesis GO:0007283 284 0.041
Mouse
cellular amino acid metabolic process GO:0006520 103 0.040
serotonin transport GO:0006837 11 0.040
reactive oxygen species biosynthetic process GO:1903409 8 0.039
cytokine production GO:0001816 319 0.039
maintenance of protein location in nucleus GO:0051457 2 0.039
nitrogen compound transport GO:0071705 271 0.039
monoamine transport GO:0015844 33 0.037
maintenance of location GO:0051235 89 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
protein localization to organelle GO:0033365 185 0.036
regulation of cytokine production GO:0001817 266 0.035
reactive nitrogen species metabolic process GO:2001057 0 0.035
cellular ketone metabolic process GO:0042180 84 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
protein localization to nucleus GO:0034504 121 0.034
regulation of neurotransmitter levels GO:0001505 87 0.034
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.033
muscle cell differentiation GO:0042692 261 0.032
glucose homeostasis GO:0042593 128 0.032
regulation of secretion by cell GO:1903530 249 0.031
regulation of neuron differentiation GO:0045664 281 0.031
unsaturated fatty acid biosynthetic process GO:0006636 15 0.030
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.030
liver development GO:0001889 66 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.029
neurotransmitter secretion GO:0007269 62 0.029
regulation of phospholipase c activity GO:1900274 3 0.029
cellular protein complex assembly GO:0043623 116 0.029
actin cytoskeleton organization GO:0030036 220 0.029
neurotransmitter transport GO:0006836 76 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
negative regulation of cell proliferation GO:0008285 296 0.028
regulation of secretion GO:0051046 274 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.027
camera type eye development GO:0043010 266 0.027
actomyosin structure organization GO:0031032 56 0.026
regulation of organelle organization GO:0033043 289 0.026
striated muscle cell development GO:0055002 125 0.026
regulation of cell cycle GO:0051726 281 0.026
response to organonitrogen compound GO:0010243 246 0.026
regulation of feeding behavior GO:0060259 3 0.026
positive regulation of cell development GO:0010720 237 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
fatty acid metabolic process GO:0006631 121 0.024
maintenance of protein localization in organelle GO:0072595 2 0.024
sensory perception GO:0007600 245 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
cellular response to hormone stimulus GO:0032870 150 0.023
positive regulation of protein modification process GO:0031401 299 0.023
cell adhesion GO:0007155 329 0.023
placenta development GO:0001890 140 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
development of primary male sexual characteristics GO:0046546 88 0.022
multicellular organismal reproductive behavior GO:0033057 23 0.022
carbohydrate metabolic process GO:0005975 230 0.022
apoptotic signaling pathway GO:0097190 306 0.022
regulation of hydrolase activity GO:0051336 246 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
Mouse
neuron migration GO:0001764 122 0.022
organelle fission GO:0048285 170 0.022
meiotic cell cycle GO:0051321 122 0.022
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.022
ion transmembrane transport GO:0034220 361 0.022
cellular response to lipid GO:0071396 145 0.021
cell division GO:0051301 120 0.021
development of primary sexual characteristics GO:0045137 143 0.021
amine metabolic process GO:0009308 45 0.021
regulation of cell cycle process GO:0010564 160 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
eating behavior GO:0042755 15 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
transmembrane transport GO:0055085 412 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
protein maturation GO:0051604 176 0.020
negative regulation of molecular function GO:0044092 258 0.020
protein catabolic process GO:0030163 221 0.020
male sex differentiation GO:0046661 109 0.020
defense response to other organism GO:0098542 197 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
chromatin organization GO:0006325 206 0.020
response to lipopolysaccharide GO:0032496 128 0.020
positive regulation of nervous system development GO:0051962 221 0.019
regulation of membrane potential GO:0042391 192 0.019
immune effector process GO:0002252 321 0.019
development of primary female sexual characteristics GO:0046545 73 0.019
positive regulation of phospholipase c activity GO:0010863 2 0.019
hepaticobiliary system development GO:0061008 67 0.019
multi organism reproductive behavior GO:0044705 29 0.019
excretion GO:0007588 22 0.019
nuclear division GO:0000280 158 0.019
stem cell development GO:0048864 219 0.019
cell growth GO:0016049 130 0.019
amide transport GO:0042886 138 0.019
peptide transport GO:0015833 133 0.019
maintenance of location in cell GO:0051651 24 0.018
female sex differentiation GO:0046660 84 0.018
peptidyl amino acid modification GO:0018193 336 0.018
gonad development GO:0008406 141 0.018
rhythmic process GO:0048511 174 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
multicellular organismal signaling GO:0035637 91 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
epithelial cell development GO:0002064 159 0.018
reproductive behavior GO:0019098 32 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of transforming growth factor beta secretion GO:2001201 1 0.017
steroid metabolic process GO:0008202 119 0.017
transmission of nerve impulse GO:0019226 76 0.017
response to peptide hormone GO:0043434 127 0.017
regulation of glucose metabolic process GO:0010906 60 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
spermatid differentiation GO:0048515 115 0.017
Mouse
negative regulation of immune system process GO:0002683 209 0.017
action potential GO:0001508 78 0.017
ras protein signal transduction GO:0007265 77 0.017
leukocyte differentiation GO:0002521 342 0.017
response to insulin GO:0032868 100 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
regulation of protein localization GO:0032880 231 0.016
negative regulation of nervous system development GO:0051961 156 0.016
metal ion homeostasis GO:0055065 189 0.016
dna metabolic process GO:0006259 303 0.016
maintenance of protein location in cell GO:0032507 20 0.016
protein ubiquitination GO:0016567 171 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
meiotic nuclear division GO:0007126 115 0.016
female gonad development GO:0008585 71 0.016
regulation of neuron projection development GO:0010975 169 0.016
response to organic cyclic compound GO:0014070 198 0.016
organ growth GO:0035265 117 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of hormone secretion GO:0046883 88 0.016
detection of stimulus GO:0051606 84 0.016
cell type specific apoptotic process GO:0097285 268 0.015
ossification GO:0001503 216 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
regulation of protein kinase activity GO:0045859 232 0.015
positive regulation of phospholipase activity GO:0010518 3 0.015
carbohydrate homeostasis GO:0033500 128 0.015
response to acid chemical GO:0001101 111 0.015
male gonad development GO:0008584 88 0.015
circulatory system process GO:0003013 197 0.015
myofibril assembly GO:0030239 34 0.015
positive regulation of cell death GO:0010942 224 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
regulation of cell activation GO:0050865 289 0.015
striated muscle tissue development GO:0014706 293 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of action potential GO:0098900 4 0.015
myeloid cell differentiation GO:0030099 233 0.015
respiratory system development GO:0060541 190 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
fat cell differentiation GO:0045444 160 0.015
positive regulation of apoptotic process GO:0043065 217 0.014
embryonic placenta development GO:0001892 98 0.014
positive regulation of cytokine production GO:0001819 174 0.014
regulation of anatomical structure size GO:0090066 178 0.014
intracellular receptor signaling pathway GO:0030522 74 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
cellular response to nutrient levels GO:0031669 64 0.014
regulation of system process GO:0044057 200 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
muscle tissue development GO:0060537 308 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
serotonin secretion GO:0001820 8 0.014
regulation of cell projection organization GO:0031344 206 0.014
histone modification GO:0016570 159 0.014
multicellular organismal aging GO:0010259 24 0.014
skeletal system development GO:0001501 356 0.014
regulation of ion transport GO:0043269 215 0.014
response to radiation GO:0009314 165 0.014
compound eye development GO:0048749 1 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
regulation of cellular response to stress GO:0080135 159 0.013
heart morphogenesis GO:0003007 178 0.013
rho protein signal transduction GO:0007266 32 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
cellular ion homeostasis GO:0006873 165 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
developmental maturation GO:0021700 193 0.013
regulation of cell motility GO:2000145 236 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of mapk cascade GO:0043408 248 0.013
lymphocyte proliferation GO:0046651 164 0.013
regulation of protein transport GO:0051223 163 0.013
regulation of ossification GO:0030278 112 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
glucose transport GO:0015758 56 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
gliogenesis GO:0042063 141 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
triglyceride metabolic process GO:0006641 51 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
Mouse
sensory perception of chemical stimulus GO:0007606 51 0.013
t cell activation GO:0042110 289 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
inflammatory response GO:0006954 244 0.013
regulation of hormone levels GO:0010817 211 0.013
stem cell maintenance GO:0019827 130 0.013
skeletal muscle organ development GO:0060538 163 0.012
leukocyte proliferation GO:0070661 172 0.012
response to extracellular stimulus GO:0009991 127 0.012
drug metabolic process GO:0017144 4 0.012
blood vessel morphogenesis GO:0048514 285 0.012
peptide secretion GO:0002790 114 0.012
positive regulation of defense response GO:0031349 124 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
mitotic cell cycle GO:0000278 195 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
positive regulation of organelle organization GO:0010638 128 0.012
axonogenesis GO:0007409 274 0.012
protein processing GO:0016485 163 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
regulation of response to wounding GO:1903034 189 0.012
synaptic transmission GO:0007268 329 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
germ cell development GO:0007281 185 0.012
Mouse
blood circulation GO:0008015 195 0.012
regulation of cellular component size GO:0032535 121 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
lymphocyte differentiation GO:0030098 242 0.012
forebrain development GO:0030900 302 0.012
cytoplasmic transport GO:0016482 234 0.012
nucleoside metabolic process GO:0009116 246 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
regulation of homeostatic process GO:0032844 182 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
cation transmembrane transport GO:0098655 266 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of proteolysis GO:0030162 164 0.012
microtubule based process GO:0007017 236 0.012
response to oxygen levels GO:0070482 62 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of protein secretion GO:0050708 82 0.011
hormone secretion GO:0046879 128 0.011
intracellular protein transport GO:0006886 204 0.011
hormone metabolic process GO:0042445 86 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
glial cell differentiation GO:0010001 131 0.011
endocytosis GO:0006897 168 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
regulation of protein maturation GO:1903317 96 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
purine containing compound metabolic process GO:0072521 311 0.011
nucleotide metabolic process GO:0009117 332 0.011
Mouse
methylation GO:0032259 134 0.011
negative regulation of protein modification process GO:0031400 163 0.011
regulation of triglyceride metabolic process GO:0090207 17 0.011
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.011
negative regulation of proteolysis GO:0045861 74 0.011
protein kinase b signaling GO:0043491 74 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
activation of immune response GO:0002253 138 0.011
ovulation cycle GO:0042698 59 0.011
negative regulation of protein processing GO:0010955 79 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
interferon gamma production GO:0032609 67 0.011
protein secretion GO:0009306 111 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
cation homeostasis GO:0055080 212 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of growth GO:0045927 104 0.011
monosaccharide transport GO:0015749 58 0.011
regulation of interleukin 10 secretion GO:2001179 4 0.011
single organism cell adhesion GO:0098602 156 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of cell growth GO:0001558 91 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
response to starvation GO:0042594 65 0.010
nucleotide catabolic process GO:0009166 217 0.010
membrane organization GO:0061024 245 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
response to growth factor GO:0070848 198 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
regulation of fat cell differentiation GO:0045598 81 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
negative regulation of cell activation GO:0050866 111 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
ear development GO:0043583 200 0.010
organic acid catabolic process GO:0016054 51 0.010
macromolecule methylation GO:0043414 120 0.010
lung development GO:0030324 164 0.010
digestive system development GO:0055123 200 0.010
purine nucleotide metabolic process GO:0006163 302 0.010
regulation of body fluid levels GO:0050878 162 0.010
regulation of reproductive process GO:2000241 66 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
protein oligomerization GO:0051259 67 0.010
hexose transport GO:0008645 56 0.010

Tbpl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.029
disease of metabolism DOID:0014667 0 0.020
brain disease DOID:936 0 0.016
musculoskeletal system disease DOID:17 0 0.013