Mus musculus

218 known processes

Lhcgr

luteinizing hormone/choriogonadotropin receptor

(Aliases: Lhr,LH-R,Gpcr19-rs1)

Lhcgr biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.997
canonical wnt signaling pathway involved in metanephric kidney development GO:0061290 2 0.988
Mouse
male gonad development GO:0008584 88 0.985
positive regulation of intracellular steroid hormone receptor signaling pathway GO:0033145 4 0.983
Mouse
wnt signaling pathway involved in kidney development GO:0061289 2 0.975
Mouse
development of primary male sexual characteristics GO:0046546 88 0.975
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.959
leydig cell differentiation GO:0033327 10 0.955
ovulation cycle GO:0042698 59 0.952
response to peptide hormone GO:0043434 127 0.946
progesterone biosynthetic process GO:0006701 1 0.938
cellular response to gonadotropin stimulus GO:0071371 4 0.922
male sex differentiation GO:0046661 109 0.900
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.897
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.896
Mouse
rhythmic process GO:0048511 174 0.892
regulation of hormone levels GO:0010817 211 0.891
g protein coupled receptor signaling pathway GO:0007186 243 0.873
response to peptide GO:1901652 136 0.872
hormone mediated signaling pathway GO:0009755 23 0.871
Rat
development of primary female sexual characteristics GO:0046545 73 0.870
amide transport GO:0042886 138 0.867
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.858
purine containing compound biosynthetic process GO:0072522 70 0.847
regulation of camp metabolic process GO:0030814 30 0.842
primary ovarian follicle growth GO:0001545 2 0.825
Mouse
female gonad development GO:0008585 71 0.810
sertoli cell proliferation GO:0060011 5 0.809
Mouse
regulation of androgen receptor signaling pathway GO:0060765 3 0.803
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.802
Mouse
response to organonitrogen compound GO:0010243 246 0.802
ovarian follicle development GO:0001541 40 0.784
steroid hormone mediated signaling pathway GO:0043401 6 0.779
antral ovarian follicle growth GO:0001547 5 0.777
steroid metabolic process GO:0008202 119 0.776
insulin secretion GO:0030073 89 0.759
response to insulin GO:0032868 100 0.750
gonad development GO:0008406 141 0.734
nephron epithelium morphogenesis GO:0072088 68 0.723
Mouse
follicle stimulating hormone signaling pathway GO:0042699 3 0.718
Mouse
positive regulation of camp metabolic process GO:0030816 19 0.707
myeloid cell differentiation GO:0030099 233 0.701
Mouse
organophosphate biosynthetic process GO:0090407 122 0.692
cellular response to insulin stimulus GO:0032869 78 0.684
development of primary sexual characteristics GO:0045137 143 0.683
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.675
Mouse
cyclic purine nucleotide metabolic process GO:0052652 43 0.672
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.668
small molecule biosynthetic process GO:0044283 132 0.664
cellular response to peptide GO:1901653 92 0.663
hormone secretion GO:0046879 128 0.649
negative regulation of bone remodeling GO:0046851 6 0.633
Mouse
mesonephric tubule development GO:0072164 94 0.633
Mouse
regulation of acetylcholine metabolic process GO:0060408 1 0.628
Mouse
regulation of secretion by cell GO:1903530 249 0.627
Mouse
response to testosterone GO:0033574 3 0.625
follicle stimulating hormone secretion GO:0046884 1 0.620
gland development GO:0048732 330 0.615
female sex differentiation GO:0046660 84 0.613
regulation of peptide secretion GO:0002791 77 0.608
regulation of nucleotide biosynthetic process GO:0030808 34 0.600
regulation of female gonad development GO:2000194 7 0.580
cellular response to peptide hormone stimulus GO:0071375 92 0.560
prostate gland morphogenetic growth GO:0060737 4 0.559
circulatory system process GO:0003013 197 0.559
Mouse
regulation of camp biosynthetic process GO:0030817 25 0.542
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.536
purine nucleotide metabolic process GO:0006163 302 0.536
multicellular organism growth GO:0035264 161 0.534
Mouse
prostate gland growth GO:0060736 13 0.525
purine ribonucleotide biosynthetic process GO:0009152 59 0.522
ribonucleotide metabolic process GO:0009259 291 0.522
spermatogenesis GO:0007283 284 0.509
trophectodermal cell proliferation GO:0001834 2 0.489
cellular lipid metabolic process GO:0044255 323 0.484
skeletal system development GO:0001501 356 0.476
regulation of steroid hormone biosynthetic process GO:0090030 4 0.475
acetate ester metabolic process GO:1900619 3 0.474
Mouse
regulation of mast cell differentiation GO:0060375 3 0.463
positive regulation of hormone secretion GO:0046887 38 0.460
androgen metabolic process GO:0008209 11 0.456
pancreatic a cell fate commitment GO:0003326 2 0.454
type b pancreatic cell proliferation GO:0044342 10 0.451
positive regulation of camp mediated signaling GO:0043950 3 0.451
carbohydrate derivative biosynthetic process GO:1901137 183 0.449
nucleotide metabolic process GO:0009117 332 0.449
ribose phosphate metabolic process GO:0019693 291 0.443
positive regulation of reproductive process GO:2000243 19 0.441
nucleoside phosphate metabolic process GO:0006753 338 0.439
cell proliferation involved in heart valve development GO:2000793 2 0.425
acetylcholine metabolic process GO:0008291 3 0.420
Mouse
seminiferous tubule development GO:0072520 14 0.416
blood circulation GO:0008015 195 0.415
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.414
sclerotome development GO:0061056 4 0.410
regulation of mesonephros development GO:0061217 24 0.408
Mouse
bone development GO:0060348 120 0.406
visceral serous pericardium development GO:0061032 2 0.406
hormone metabolic process GO:0042445 86 0.404
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.402
cellular response to hormone stimulus GO:0032870 150 0.402
inner ear morphogenesis GO:0042472 101 0.395
Mouse
regulation of hormone secretion GO:0046883 88 0.395
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.384
negative regulation of bone resorption GO:0045779 6 0.382
Mouse
mitral valve development GO:0003174 4 0.382
adult behavior GO:0030534 135 0.379
Mouse
purine containing compound metabolic process GO:0072521 311 0.379
ureteric bud development GO:0001657 94 0.369
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.348
regulation of myeloid leukocyte differentiation GO:0002761 58 0.334
Mouse
triglyceride metabolic process GO:0006641 51 0.327
regulation of tube size GO:0035150 57 0.320
intracellular receptor signaling pathway GO:0030522 74 0.319
Mouse
sertoli cell differentiation GO:0060008 18 0.318
Mouse
urogenital system development GO:0001655 261 0.317
Mouse
regulation of secretion GO:0051046 274 0.314
Mouse
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.312
nucleoside phosphate biosynthetic process GO:1901293 79 0.310
nucleobase containing small molecule metabolic process GO:0055086 352 0.309
bmp signaling pathway GO:0030509 93 0.307
regulation of purine nucleotide metabolic process GO:1900542 169 0.304
divalent inorganic cation transport GO:0072511 178 0.303
Rat
nephron tubule development GO:0072080 84 0.302
Mouse
positive regulation of inositol trisphosphate biosynthetic process GO:0032962 2 0.301
response to follicle stimulating hormone GO:0032354 1 0.300
kidney morphogenesis GO:0060993 83 0.299
Mouse
regulation of carbohydrate biosynthetic process GO:0043255 40 0.298
positive regulation of secretion by cell GO:1903532 114 0.296
nucleotide biosynthetic process GO:0009165 78 0.296
cardiac epithelial to mesenchymal transition GO:0060317 18 0.294
cellular response to antibiotic GO:0071236 4 0.293
cellular response to organonitrogen compound GO:0071417 145 0.292
polyol biosynthetic process GO:0046173 13 0.292
neuropeptide signaling pathway GO:0007218 19 0.291
neuron migration GO:0001764 122 0.290
regulation of leukocyte differentiation GO:1902105 159 0.284
Mouse
aortic valve morphogenesis GO:0003180 4 0.284
cardiac muscle tissue development GO:0048738 130 0.274
auditory receptor cell fate determination GO:0042668 3 0.273
progesterone metabolic process GO:0042448 4 0.272
immune response regulating signaling pathway GO:0002764 125 0.271
Mouse
camp metabolic process GO:0046058 40 0.269
ribose phosphate biosynthetic process GO:0046390 59 0.264
regulation of fatty acid metabolic process GO:0019217 28 0.264
organ growth GO:0035265 117 0.263
testosterone biosynthetic process GO:0061370 2 0.262
trachea formation GO:0060440 3 0.262
cell cell signaling involved in kidney development GO:0060995 2 0.257
Mouse
peptide secretion GO:0002790 114 0.257
epithelial tube morphogenesis GO:0060562 303 0.255
Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.255
connective tissue development GO:0061448 179 0.255
maternal process involved in female pregnancy GO:0060135 32 0.254
peptide transport GO:0015833 133 0.253
purine nucleotide biosynthetic process GO:0006164 65 0.253
lymphocyte differentiation GO:0030098 242 0.250
Mouse
development of secondary male sexual characteristics GO:0046544 3 0.247
uterus development GO:0060065 16 0.246
regulation of organ morphogenesis GO:2000027 144 0.241
Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.239
mammary gland lobule development GO:0061377 22 0.238
epithelial cell development GO:0002064 159 0.235
Mouse
trophectodermal cellular morphogenesis GO:0001831 3 0.235
kidney rudiment formation GO:0072003 3 0.233
b cell differentiation GO:0030183 78 0.233
Mouse
positive regulation of transferase activity GO:0051347 167 0.232
renal tubule development GO:0061326 87 0.229
Mouse
response to cholesterol GO:0070723 4 0.229
skeletal system morphogenesis GO:0048705 203 0.227
fatty acid biosynthetic process GO:0006633 41 0.226
regulation of nucleotide metabolic process GO:0006140 169 0.226
lipid biosynthetic process GO:0008610 179 0.225
negative regulation of synapse maturation GO:2000297 2 0.225
inositol phosphate biosynthetic process GO:0032958 6 0.221
carbohydrate metabolic process GO:0005975 230 0.221
sertoli cell development GO:0060009 15 0.220
Mouse
toll like receptor signaling pathway GO:0002224 38 0.219
Mouse
hemangioblast cell differentiation GO:0060217 1 0.215
response to camp GO:0051591 14 0.209
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.209
dibenzo p dioxin metabolic process GO:0018894 1 0.203
anatomical structure homeostasis GO:0060249 145 0.203
Mouse
extracellular structure organization GO:0043062 148 0.202
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.201
Mouse
metanephric tubule development GO:0072170 18 0.201
Mouse
ossification GO:0001503 216 0.197
Mouse
fatty acid metabolic process GO:0006631 121 0.197
mesonephric tubule morphogenesis GO:0072171 63 0.196
Mouse
muscle cell differentiation GO:0042692 261 0.193
dna packaging GO:0006323 30 0.192
Mouse
morphogenesis of a branching structure GO:0001763 203 0.192
Mouse
nephron development GO:0072006 109 0.190
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.187
Mouse
regulation of exit from mitosis GO:0007096 1 0.186
mitotic chromosome condensation GO:0007076 1 0.186
embryonic viscerocranium morphogenesis GO:0048703 8 0.185
embryonic hemopoiesis GO:0035162 23 0.181
vascular process in circulatory system GO:0003018 62 0.176
epithelial cell proliferation involved in mammary gland duct elongation GO:0060750 5 0.174
positive regulation of alcohol biosynthetic process GO:1902932 5 0.174
positive regulation of immature t cell proliferation GO:0033091 4 0.174
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.170
Mouse
c21 steroid hormone biosynthetic process GO:0006700 3 0.170
cholesterol homeostasis GO:0042632 44 0.168
cyclic nucleotide metabolic process GO:0009187 59 0.168
stem cell proliferation GO:0072089 117 0.168
endocrine system development GO:0035270 98 0.167
creatinine metabolic process GO:0046449 3 0.167
glandular epithelial cell differentiation GO:0002067 38 0.166
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.165
activation of adenylate cyclase activity GO:0007190 4 0.165
regulation of striated muscle cell apoptotic process GO:0010662 11 0.164
benzene containing compound metabolic process GO:0042537 5 0.163
positive regulation of kidney development GO:0090184 28 0.162
Mouse
carbohydrate homeostasis GO:0033500 128 0.162
camp biosynthetic process GO:0006171 31 0.161
metanephric glomerulus development GO:0072224 13 0.160
Mouse
nitrogen compound transport GO:0071705 271 0.160
regulation of cartilage development GO:0061035 44 0.159
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.158
prostate epithelial cord elongation GO:0060523 3 0.158
inositol trisphosphate biosynthetic process GO:0032959 5 0.158
positive regulation of protein kinase activity GO:0045860 144 0.157
regulation of kidney development GO:0090183 40 0.156
Mouse
positive regulation of insulin secretion GO:0032024 26 0.156
cell aging GO:0007569 35 0.155
mesonephric epithelium development GO:0072163 94 0.154
Mouse
regulation of peptide transport GO:0090087 91 0.154
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.153
activation of immune response GO:0002253 138 0.151
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.151
cardiac muscle cell apoptotic process GO:0010659 10 0.151
fertilization GO:0009566 127 0.150
negative regulation of neuron apoptotic process GO:0043524 92 0.149
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.149
cell cell signaling involved in metanephros development GO:0072204 2 0.148
Mouse
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.148
regulation of protein localization GO:0032880 231 0.146
Mouse
single fertilization GO:0007338 82 0.146
embryonic heart tube formation GO:0003144 1 0.146
regulation of retina development in camera type eye GO:1902866 3 0.144
fused antrum stage GO:0048165 1 0.143
synaptic transmission GO:0007268 329 0.142
Mouse
pancreas development GO:0031016 57 0.142
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.141
metanephric nephron development GO:0072210 34 0.141
Mouse
chondrocyte differentiation GO:0002062 72 0.140
regulation of blood pressure GO:0008217 93 0.140
Mouse
pancreatic pp cell fate commitment GO:0003329 2 0.140
regionalization GO:0003002 337 0.138
glycerolipid metabolic process GO:0046486 122 0.138
negative regulation of insulin secretion GO:0046676 14 0.137
negative regulation of molecular function GO:0044092 258 0.136
positive regulation of peptide secretion GO:0002793 33 0.136
carbohydrate biosynthetic process GO:0016051 74 0.135
positive regulation of male gonad development GO:2000020 6 0.134
prostate gland development GO:0030850 48 0.134
cellular response to organic cyclic compound GO:0071407 87 0.133
regulation of fatty acid biosynthetic process GO:0042304 12 0.132
regulation of lyase activity GO:0051339 13 0.131
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.131
regulation of circadian rhythm GO:0042752 58 0.130
hormone biosynthetic process GO:0042446 16 0.130
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.129
regulation of neuron death GO:1901214 134 0.128
cardiac ventricle morphogenesis GO:0003208 50 0.126
regulation of organelle organization GO:0033043 289 0.126
Mouse
adrenal gland development GO:0030325 18 0.126
regulation of cyclase activity GO:0031279 13 0.124
regulation of blood volume by renal aldosterone GO:0002017 1 0.123
male sex determination GO:0030238 14 0.123
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.122
extracellular matrix organization GO:0030198 147 0.121
Mouse
cartilage development GO:0051216 140 0.118
muscle cell apoptotic process GO:0010657 18 0.118
regulation of morphogenesis of a branching structure GO:0060688 53 0.118
Mouse
phenol containing compound metabolic process GO:0018958 60 0.117
lipid transport GO:0006869 98 0.117
Rat
renal sodium excretion GO:0035812 3 0.116
androgen biosynthetic process GO:0006702 4 0.116
positive regulation of kinase activity GO:0033674 155 0.115
regulation of blood vessel size GO:0050880 56 0.114
positive regulation of mesonephros development GO:0061213 20 0.114
Mouse
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.114
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.113
cardiac muscle tissue morphogenesis GO:0055008 44 0.112
response to steroid hormone GO:0048545 56 0.111
nephron epithelium development GO:0072009 92 0.111
Mouse
sulfur compound metabolic process GO:0006790 100 0.110
erythrocyte differentiation GO:0030218 88 0.110
acylglycerol metabolic process GO:0006639 55 0.109
metanephric nephron epithelium development GO:0072243 19 0.109
Mouse
negative regulation of immune system process GO:0002683 209 0.109
Mouse
astrocyte fate commitment GO:0060018 4 0.108
cell type specific apoptotic process GO:0097285 268 0.108
cellular ketone metabolic process GO:0042180 84 0.108
negative regulation of female gonad development GO:2000195 3 0.107
regulation of transferase activity GO:0051338 263 0.107
hormone mediated apoptotic signaling pathway GO:0008628 1 0.107
dicarboxylic acid metabolic process GO:0043648 18 0.107
response to monosaccharide GO:0034284 67 0.099
regulation of camp mediated signaling GO:0043949 7 0.098
blood vessel morphogenesis GO:0048514 285 0.098
response to xenobiotic stimulus GO:0009410 13 0.097
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.097
b cell activation GO:0042113 161 0.097
Mouse
neuron death GO:0070997 154 0.097
regulation of cell migration GO:0030334 219 0.096
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.096
Mouse
norepinephrine epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001994 3 0.096
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.096
positive regulation of retinoic acid receptor signaling pathway GO:0048386 3 0.095
cellular response to ethanol GO:0071361 3 0.095
organonitrogen compound biosynthetic process GO:1901566 192 0.094
regulation of cell cycle GO:0051726 281 0.094
positive regulation of peptide hormone secretion GO:0090277 31 0.094
lipid catabolic process GO:0016042 69 0.094
embryonic skeletal system morphogenesis GO:0048704 91 0.093
canonical wnt signaling pathway GO:0060070 130 0.092
Mouse
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.092
lateral mesoderm morphogenesis GO:0048369 3 0.092
regulation of toll like receptor signaling pathway GO:0034121 20 0.092
Mouse
cell fate determination GO:0001709 32 0.092
dna conformation change GO:0071103 37 0.092
Mouse
response to oxygen levels GO:0070482 62 0.090
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.090
regulation of stem cell proliferation GO:0072091 78 0.089
regulation of adenylate cyclase activity GO:0045761 10 0.089
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.088
inositol trisphosphate metabolic process GO:0032957 5 0.088
ventricular cardiac muscle tissue development GO:0003229 38 0.088
negative regulation of cell motility GO:2000146 61 0.088
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.088
positive regulation of stem cell differentiation GO:2000738 23 0.087
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.087
negative regulation of cell cycle GO:0045786 123 0.087
protein secretion GO:0009306 111 0.086
Mouse
skeletal muscle organ development GO:0060538 163 0.086
male anatomical structure morphogenesis GO:0090598 4 0.086
polyol metabolic process GO:0019751 26 0.086
vitamin d catabolic process GO:0042369 1 0.085
inner ear receptor cell differentiation GO:0060113 61 0.085
Mouse
positive regulation of erythrocyte differentiation GO:0045648 11 0.085
amine metabolic process GO:0009308 45 0.084
Mouse
adult locomotory behavior GO:0008344 91 0.084
Mouse
regulation of steroid biosynthetic process GO:0050810 26 0.084
paraxial mesodermal cell differentiation GO:0048342 2 0.084
regulation of microtubule polymerization GO:0031113 7 0.084
mammary gland branching involved in pregnancy GO:0060745 6 0.083
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.083
male gamete generation GO:0048232 285 0.083
regulation of myeloid cell differentiation GO:0045637 96 0.083
Mouse
embryonic skeletal system development GO:0048706 120 0.082
kidney development GO:0001822 213 0.082
Mouse
cardiocyte differentiation GO:0035051 87 0.082
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.082
metanephros development GO:0001656 79 0.082
Mouse
regulation of tolerance induction to self antigen GO:0002649 1 0.081
muscle cell proliferation GO:0033002 52 0.081
angiogenesis GO:0001525 201 0.080
cellular modified amino acid metabolic process GO:0006575 63 0.079
regulation of fatty acid beta oxidation GO:0031998 1 0.079
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.078
kidney epithelium development GO:0072073 121 0.078
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.078
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.078
cartilage morphogenesis GO:0060536 11 0.077
glucocorticoid metabolic process GO:0008211 9 0.077
positive regulation of apoptotic process GO:0043065 217 0.077
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.076
regulation of epithelial cell proliferation GO:0050678 141 0.076
signal transduction in absence of ligand GO:0038034 55 0.076
somatic sex determination GO:0018993 2 0.075
striated muscle cell apoptotic process GO:0010658 12 0.075
positive regulation of fatty acid oxidation GO:0046321 4 0.075
positive regulation of carbohydrate metabolic process GO:0045913 30 0.075
mammary gland alveolus development GO:0060749 22 0.074
positive regulation of secretion GO:0051047 130 0.074
response to decreased oxygen levels GO:0036293 59 0.073
trophoblast giant cell differentiation GO:0060707 15 0.073
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.073
protein processing GO:0016485 163 0.072
regulation of reproductive process GO:2000241 66 0.072
mesonephros development GO:0001823 97 0.072
Mouse
appendage development GO:0048736 166 0.072
diencephalon development GO:0021536 63 0.072
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.072
paraxial mesodermal cell fate commitment GO:0048343 2 0.071
positive regulation of exit from mitosis GO:0031536 1 0.071
luteinization GO:0001553 8 0.070
inner ear receptor cell development GO:0060119 39 0.070
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.070
sperm chromatin condensation GO:0035092 8 0.070
Mouse
peptide hormone secretion GO:0030072 109 0.070
multi organism behavior GO:0051705 62 0.070
granulosa cell differentiation GO:0060014 1 0.070
cell cycle arrest GO:0007050 37 0.070
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.069
monocarboxylic acid metabolic process GO:0032787 191 0.069
glucose homeostasis GO:0042593 128 0.069
auditory receptor cell fate specification GO:0042667 1 0.069
negative regulation of neuron death GO:1901215 98 0.069
axonogenesis GO:0007409 274 0.069
acylglycerol homeostasis GO:0055090 16 0.068
cardioblast proliferation GO:0003263 8 0.067
positive regulation of bmp signaling pathway GO:0030513 23 0.067
integrin biosynthetic process GO:0045112 1 0.067
carbon catabolite regulation of transcription GO:0045990 4 0.066
calcium mediated signaling GO:0019722 46 0.066
Rat
cellular aldehyde metabolic process GO:0006081 12 0.066
immune response activating signal transduction GO:0002757 116 0.065
Mouse
neuron apoptotic process GO:0051402 142 0.065
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.065
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.064
negative regulation of peptide hormone secretion GO:0090278 16 0.064
osteoclast differentiation GO:0030316 62 0.063
Mouse
monosaccharide biosynthetic process GO:0046364 44 0.063
enteroendocrine cell differentiation GO:0035883 16 0.062
regulation of transmembrane transport GO:0034762 128 0.062
positive regulation of lymphocyte differentiation GO:0045621 61 0.062
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.062
nephron tubule morphogenesis GO:0072078 68 0.061
Mouse
definitive hemopoiesis GO:0060216 20 0.061
maintenance of protein localization in organelle GO:0072595 2 0.061
lateral mesodermal cell differentiation GO:0048371 3 0.060
regulation of epithelial cell proliferation involved in prostate gland development GO:0060768 10 0.060
intestinal epithelial cell maturation GO:0060574 2 0.060
negative regulation of nervous system development GO:0051961 156 0.060
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure GO:0001985 1 0.059
insulin receptor signaling pathway GO:0008286 49 0.058
positive regulation of innate immune response GO:0045089 80 0.058
Mouse
cellular alcohol biosynthetic process GO:0044108 3 0.058
metanephric epithelium development GO:0072207 21 0.058
Mouse
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.057
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.057
regulation of cell motility GO:2000145 236 0.056
triglyceride homeostasis GO:0070328 15 0.056
atrioventricular valve morphogenesis GO:0003181 13 0.055
bone remodeling GO:0046849 53 0.055
Mouse
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.055
Mouse
regulation of neural retina development GO:0061074 3 0.055
glomerular mesangial cell differentiation GO:0072008 3 0.055
pancreatic pp cell differentiation GO:0003312 2 0.054
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.054
neuroblast proliferation GO:0007405 49 0.054
regulation of metal ion transport GO:0010959 106 0.054
Rat
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.054
positive regulation of cell motility GO:2000147 116 0.054
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.054
heart formation GO:0060914 16 0.053
cell cell recognition GO:0009988 44 0.053
regulation of tissue remodeling GO:0034103 38 0.053
Mouse
bone morphogenesis GO:0060349 78 0.053
positive regulation of atpase activity GO:0032781 3 0.053
actomyosin structure organization GO:0031032 56 0.053
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.053
negative regulation of cell proliferation GO:0008285 296 0.053
positive regulation of leukocyte differentiation GO:1902107 86 0.053
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.053
receptor internalization GO:0031623 16 0.053
regulation of feeding behavior GO:0060259 3 0.052
lateral mesoderm formation GO:0048370 3 0.052
leukocyte differentiation GO:0002521 342 0.052
Mouse
mesenchymal cell proliferation GO:0010463 44 0.052
regulation of male gonad development GO:2000018 7 0.052
mitotic cell cycle GO:0000278 195 0.051
alpha beta t cell activation GO:0046631 91 0.051
vitamin catabolic process GO:0009111 1 0.051
response to nutrient levels GO:0031667 109 0.051
sterol homeostasis GO:0055092 45 0.050
somatostatin signaling pathway GO:0038170 2 0.050
germline stem cell asymmetric division GO:0098728 2 0.050
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.050
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.050
multicellular organismal homeostasis GO:0048871 164 0.050
Mouse
coronary vasculature development GO:0060976 12 0.049
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.049
positive regulation of nucleotide metabolic process GO:0045981 114 0.049
regulation of auditory receptor cell differentiation GO:0045607 4 0.049
glycoprotein biosynthetic process GO:0009101 89 0.049

Lhcgr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
female reproductive system disease DOID:229 0 0.924
disease of anatomical entity DOID:7 0 0.924
reproductive system disease DOID:15 0 0.924
ovarian disease DOID:1100 0 0.806
endocrine system disease DOID:28 0 0.093
immune system disease DOID:2914 0 0.086
hematopoietic system disease DOID:74 0 0.086
disease of metabolism DOID:0014667 0 0.064
lipid metabolism disorder DOID:3146 0 0.056
inherited metabolic disorder DOID:655 0 0.056
prostate cancer DOID:10283 0 0.051
male reproductive organ cancer DOID:3856 0 0.051
reproductive organ cancer DOID:193 0 0.051
cancer DOID:162 0 0.051
disease of cellular proliferation DOID:14566 0 0.051
organ system cancer DOID:0050686 0 0.051