Mus musculus

127 known processes

Acvr1

activin A receptor, type 1

(Aliases: ALK2,Tsk7L,Acvrlk2,Alk-2,ActRIA,Acvr,Alk8,SKR1,ActR-I,D330013D15Rik)

Acvr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
embryonic organ morphogenesis GO:0048562 276 0.999
Human Mouse
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.999
Mouse
trachea formation GO:0060440 3 0.998
Mouse
mesenchyme development GO:0060485 152 0.998
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.998
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.997
Human Mouse
mesenchymal cell differentiation GO:0048762 107 0.997
blood vessel morphogenesis GO:0048514 285 0.996
stem cell development GO:0048864 219 0.994
hindbrain tangential cell migration GO:0021934 2 0.991
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.990
stem cell differentiation GO:0048863 268 0.988
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.987
neural tube closure GO:0001843 90 0.987
heart field specification GO:0003128 6 0.978
ameboidal type cell migration GO:0001667 128 0.977
mesenchymal cell development GO:0014031 93 0.977
mapk cascade GO:0000165 281 0.977
skeletal system morphogenesis GO:0048705 203 0.974
Mouse
endocardial cell differentiation GO:0060956 4 0.974
Human
morphogenesis of a branching structure GO:0001763 203 0.973
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.972
renal system development GO:0072001 225 0.971
Mouse
regulation of cell adhesion GO:0030155 154 0.971
Worm
endodermal cell fate commitment GO:0001711 12 0.970
endocardial cushion formation GO:0003272 13 0.970
Mouse
heart morphogenesis GO:0003007 178 0.969
Human Mouse
appendage morphogenesis GO:0035107 149 0.969
Mouse Fly
regulation of lung blood pressure GO:0014916 2 0.969
Mouse
regulation of extent of cell growth GO:0061387 52 0.969
Mouse
response to growth factor GO:0070848 198 0.969
cartilage development GO:0051216 140 0.968
Mouse
neuron projection guidance GO:0097485 141 0.968
Mouse
endocrine system development GO:0035270 98 0.968
Mouse
neural crest cell development GO:0014032 48 0.967
embryonic skeletal system development GO:0048706 120 0.966
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.966
Human Mouse Fly
regulation of smad protein import into nucleus GO:0060390 3 0.960
cell migration to the midline involved in heart development GO:0003318 1 0.960
lateral mesodermal cell fate commitment GO:0048372 2 0.959
Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.958
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.954
positive regulation of cell migration GO:0030335 109 0.953
Mouse
endothelial cell differentiation GO:0045446 41 0.953
Human Mouse
stem cell proliferation GO:0072089 117 0.950
Mouse
appendage development GO:0048736 166 0.947
Mouse Fly
commissural neuron axon guidance GO:0071679 8 0.945
regionalization GO:0003002 337 0.944
Human Mouse Fly
regulation of mapk cascade GO:0043408 248 0.944
neural crest cell differentiation GO:0014033 54 0.943
negative regulation of endothelial cell differentiation GO:0045602 2 0.942
Mouse
growth plate cartilage chondrocyte development GO:0003431 3 0.940
Mouse
regulation of cartilage development GO:0061035 44 0.940
Mouse
pituitary gland development GO:0021983 38 0.940
Mouse
chondrocyte hypertrophy GO:0003415 4 0.939
Mouse
neuron projection extension GO:1990138 64 0.937
Mouse
negative regulation of axon guidance GO:1902668 8 0.936
regulation of cell migration GO:0030334 219 0.935
Mouse
anatomical structure arrangement GO:0048532 20 0.934
Mouse
retina vasculature development in camera type eye GO:0061298 17 0.933
Mouse
growth plate cartilage development GO:0003417 14 0.932
Mouse
camera type eye development GO:0043010 266 0.931
Mouse
cardiac muscle tissue development GO:0048738 130 0.927
Human
regulation of organ morphogenesis GO:2000027 144 0.925
Mouse
clara cell differentiation GO:0060486 4 0.923
branching morphogenesis of an epithelial tube GO:0048754 159 0.921
regulation of astrocyte differentiation GO:0048710 20 0.916
mesendoderm development GO:0048382 3 0.915
Mouse
lateral mesoderm formation GO:0048370 3 0.913
Mouse
ear morphogenesis GO:0042471 118 0.910
salivary gland morphogenesis GO:0007435 33 0.907
positive regulation of protein phosphorylation GO:0001934 242 0.907
Human Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.906
regulation of cell aging GO:0090342 9 0.905
Mouse
exocrine system development GO:0035272 45 0.905
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.901
embryonic heart tube development GO:0035050 65 0.899
Human
chondrocyte development GO:0002063 24 0.898
Mouse
somitogenesis GO:0001756 69 0.897
Mouse
regulation of mesodermal cell fate specification GO:0042661 5 0.891
Mouse
paraxial mesoderm structural organization GO:0048352 1 0.889
Mouse
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.888
Mouse
negative regulation of axon extension GO:0030517 19 0.887
negative regulation of epithelial cell proliferation GO:0050680 64 0.885
Mouse
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.884
neural plate mediolateral regionalization GO:0021998 1 0.883
Mouse
neural tube formation GO:0001841 108 0.882
cellular response to growth factor stimulus GO:0071363 197 0.882
neural crest cell migration GO:0001755 32 0.882
regulation of chondrocyte differentiation GO:0032330 33 0.882
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.881
positive regulation of chemotaxis GO:0050921 38 0.881
Mouse
respiratory tube development GO:0030323 167 0.879
Mouse
single organismal cell cell adhesion GO:0016337 131 0.876
positive regulation of neuron differentiation GO:0045666 141 0.876
Mouse
liver development GO:0001889 66 0.874
response to cholesterol GO:0070723 4 0.873
Mouse
regulation of neuron projection development GO:0010975 169 0.869
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.865
ovarian cumulus expansion GO:0001550 1 0.864
Mouse
germ line stem cell division GO:0042078 2 0.863
Fly
positive regulation of mapk cascade GO:0043410 170 0.861
limb development GO:0060173 166 0.860
Mouse
endodermal cell fate specification GO:0001714 4 0.859
growth plate cartilage chondrocyte growth GO:0003430 2 0.855
Mouse
endochondral bone morphogenesis GO:0060350 50 0.854
Mouse
myeloid cell differentiation GO:0030099 233 0.854
Mouse
axon extension involved in axon guidance GO:0048846 14 0.851
Mouse
bronchus morphogenesis GO:0060434 2 0.851
Mouse
embryonic heart tube left right pattern formation GO:0060971 5 0.848
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.847
striated muscle tissue development GO:0014706 293 0.846
Human Rat
respiratory system development GO:0060541 190 0.845
Mouse
lateral mesoderm morphogenesis GO:0048369 3 0.839
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.838
forebrain development GO:0030900 302 0.836
Mouse
nephron tubule morphogenesis GO:0072078 68 0.836
apoptotic signaling pathway GO:0097190 306 0.833
Human Mouse
lateral mesodermal cell differentiation GO:0048371 3 0.828
Mouse
regulation of endodermal cell fate specification GO:0042663 2 0.826
gastrulation GO:0007369 116 0.826
regulation of apoptotic signaling pathway GO:2001233 197 0.824
Human Mouse
activin receptor signaling pathway GO:0032924 18 0.824
smoothened signaling pathway GO:0007224 105 0.823
Mouse
trunk neural crest cell migration GO:0036484 4 0.823
cellular amine metabolic process GO:0044106 44 0.822
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.821
Mouse
negative regulation of cell development GO:0010721 169 0.821
Mouse
muscle tissue development GO:0060537 308 0.821
Human Rat
regulation of tube size GO:0035150 57 0.819
Mouse
kidney development GO:0001822 213 0.817
Mouse
positive regulation of odontogenesis GO:0042482 4 0.813
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.812
Mouse
cardiac septum morphogenesis GO:0060411 46 0.810
Human
wnt signaling pathway GO:0016055 188 0.809
determination of left right symmetry GO:0007368 80 0.806
epithelial tube morphogenesis GO:0060562 303 0.804
embryonic epithelial tube formation GO:0001838 130 0.804
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.803
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.801
Human
muscle fiber development GO:0048747 76 0.800
negative regulation of gastrulation GO:2000542 3 0.798
positive regulation of transferase activity GO:0051347 167 0.797
Mouse
regulation of hormone levels GO:0010817 211 0.795
Mouse
axon guidance GO:0007411 141 0.792
Mouse
cardioblast migration GO:0003260 1 0.789
hindbrain development GO:0030902 128 0.784
regulation of anti mullerian hormone signaling pathway GO:1902612 1 0.783
Mouse
cell growth GO:0016049 130 0.782
Mouse
endoderm development GO:0007492 45 0.781
Mouse
embryonic limb morphogenesis GO:0030326 126 0.779
Mouse
chondrocyte differentiation GO:0002062 72 0.778
Mouse
homeostasis of number of cells GO:0048872 210 0.778
mesenchymal cell proliferation GO:0010463 44 0.777
Mouse
positive regulation of cell death GO:0010942 224 0.776
Mouse
erythrocyte differentiation GO:0030218 88 0.776
forebrain neuron development GO:0021884 30 0.775
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.774
skeletal system development GO:0001501 356 0.772
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.769
Mouse
ventricular septum morphogenesis GO:0060412 27 0.769
cell adhesion GO:0007155 329 0.766
Worm
negative regulation of cartilage development GO:0061037 17 0.763
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.762
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.760
axonogenesis involved in innervation GO:0060385 5 0.760
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.759
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.756
cardiac epithelial to mesenchymal transition GO:0060317 18 0.751
regulation of chemotaxis GO:0050920 53 0.749
Mouse
male sex differentiation GO:0046661 109 0.749
Mouse Worm
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.745
regulation of tolerance induction to self antigen GO:0002649 1 0.745
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.741
Human
mammary gland morphogenesis GO:0060443 54 0.739
Mouse
single organism cell adhesion GO:0098602 156 0.737
erk1 and erk2 cascade GO:0070371 77 0.736
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.730
cardiac muscle cell differentiation GO:0055007 69 0.730
Human
oocyte construction GO:0007308 2 0.728
embryonic skeletal system morphogenesis GO:0048704 91 0.728
Mouse
digestive system development GO:0055123 200 0.727
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.726
secondary heart field specification GO:0003139 6 0.723
cardiocyte differentiation GO:0035051 87 0.719
Human
digestive tract morphogenesis GO:0048546 147 0.718
kidney morphogenesis GO:0060993 83 0.716
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.715
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.715
Human
cartilage condensation GO:0001502 18 0.712
Mouse
venous blood vessel development GO:0060841 13 0.712
Mouse
ureteric bud morphogenesis GO:0060675 62 0.711
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.711
telencephalon development GO:0021537 186 0.710
growth plate cartilage chondrocyte differentiation GO:0003418 5 0.707
Mouse
artery development GO:0060840 53 0.707
Mouse
oocyte axis specification GO:0007309 2 0.705
lens fiber cell apoptotic process GO:1990086 4 0.704
Mouse
regulation of cell motility GO:2000145 236 0.703
Mouse
ventricular cardiac muscle cell differentiation GO:0055012 17 0.702
response to sterol GO:0036314 4 0.701
Mouse
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.697
regulation of endodermal cell differentiation GO:1903224 2 0.696
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.692
negative regulation of astrocyte differentiation GO:0048712 10 0.690
fused antrum stage GO:0048165 1 0.689
Mouse
blood circulation GO:0008015 195 0.688
Mouse
regulation of axon extension GO:0030516 43 0.687
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.687
Fly
regulation of cellular response to growth factor stimulus GO:0090287 82 0.686
Fly
axonogenesis GO:0007409 274 0.686
Mouse
pathway restricted smad protein phosphorylation GO:0060389 10 0.685
Human
locus ceruleus development GO:0021703 1 0.685
positive regulation of epithelial cell migration GO:0010634 19 0.683
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.679
sympathetic ganglion development GO:0061549 9 0.678
formation of primary germ layer GO:0001704 77 0.676
embryonic digit morphogenesis GO:0042733 56 0.676
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.671
Fly
positive regulation of stress activated mapk cascade GO:0032874 48 0.671
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.671
positive regulation of map kinase activity GO:0043406 84 0.669
mesodermal cell migration GO:0008078 4 0.668
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.667
Mouse
mesoderm structural organization GO:0048338 1 0.665
Mouse
myelination in peripheral nervous system GO:0022011 19 0.665
positive regulation of stem cell proliferation GO:2000648 59 0.665
Mouse
positive regulation of tolerance induction to self antigen GO:0002651 1 0.664
Mouse
regulation of protein kinase activity GO:0045859 232 0.663
Mouse
lung induction GO:0060492 3 0.663
tube formation GO:0035148 140 0.658
diencephalon development GO:0021536 63 0.657
Mouse
positive regulation of kinase activity GO:0033674 155 0.657
Mouse
inner ear morphogenesis GO:0042472 101 0.657
regulation of neuron differentiation GO:0045664 281 0.656
Mouse
regulation of system process GO:0044057 200 0.656
Mouse
hormone secretion GO:0046879 128 0.653
Mouse
pyramidal neuron migration GO:0021852 1 0.652
urogenital system development GO:0001655 261 0.651
Mouse Rat
regulation of cellular senescence GO:2000772 6 0.651
Mouse
epithelial cell migration GO:0010631 63 0.646
Mouse
cell migration in hindbrain GO:0021535 16 0.646
positive regulation of cell motility GO:2000147 116 0.645
Mouse
endothelial cell proliferation GO:0001935 27 0.643
Mouse
palate development GO:0060021 76 0.640
Mouse
inflammatory response GO:0006954 244 0.637
stress activated protein kinase signaling cascade GO:0031098 81 0.633
circulatory system process GO:0003013 197 0.633
Mouse
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.633
positive regulation of smad protein import into nucleus GO:0060391 2 0.625
hepaticobiliary system development GO:0061008 67 0.621
positive regulation of cardioblast differentiation GO:0051891 3 0.621
regulation of bmp signaling pathway GO:0030510 60 0.619
Mouse Fly
positive regulation of protein modification process GO:0031401 299 0.619
Human Mouse
female sex differentiation GO:0046660 84 0.619
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.619
positive regulation of bmp signaling pathway GO:0030513 23 0.617
Mouse
endothelium development GO:0003158 45 0.616
Human Mouse
negative regulation of anti mullerian hormone signaling pathway GO:1902613 1 0.615
Mouse
positive regulation of retinal ganglion cell axon guidance GO:1902336 2 0.614
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.613
p38mapk cascade GO:0038066 4 0.613
regulation of wnt signaling pathway GO:0030111 123 0.611
regulation of cysteine type endopeptidase activity GO:2000116 65 0.610
bmp signaling pathway GO:0030509 93 0.609
Human Mouse Fly
positive regulation of apoptotic process GO:0043065 217 0.609
Mouse
metanephric mesenchyme morphogenesis GO:0072133 4 0.608
embryonic appendage morphogenesis GO:0035113 126 0.608
Mouse
kidney mesenchyme morphogenesis GO:0072131 4 0.607
regulation of kinase activity GO:0043549 249 0.607
Mouse
gastrulation with mouth forming second GO:0001702 29 0.606
endothelial cell migration GO:0043542 44 0.604
Mouse
peptidyl threonine phosphorylation GO:0018107 31 0.603
Human Mouse
determination of heart left right asymmetry GO:0061371 48 0.600
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.600
developmental growth involved in morphogenesis GO:0060560 138 0.599
Mouse
regulation of gliogenesis GO:0014013 50 0.599
regulation of stress activated mapk cascade GO:0032872 69 0.598
embryonic camera type eye development GO:0031076 36 0.597
positive regulation of cellular amine metabolic process GO:0033240 5 0.595
negative regulation of endothelial cell proliferation GO:0001937 8 0.590
Mouse
regulation of glial cell differentiation GO:0045685 41 0.590
negative regulation of neuron projection development GO:0010977 50 0.588
muscle cell proliferation GO:0033002 52 0.587
lung alveolus development GO:0048286 45 0.585
Mouse
mullerian duct regression GO:0001880 1 0.583
Mouse
regulation of homeostatic process GO:0032844 182 0.580
regulation of protein localization GO:0032880 231 0.577
negative regulation of glial cell differentiation GO:0045686 21 0.575
gland development GO:0048732 330 0.575
Mouse
regulation of ossification GO:0030278 112 0.572
Human
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.571
chondrocyte development involved in endochondral bone morphogenesis GO:0003433 5 0.571
Mouse
regulation of axon guidance GO:1902667 13 0.570
Mouse
somite development GO:0061053 81 0.568
Mouse
mesoderm morphogenesis GO:0048332 64 0.567
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.562
developmental cell growth GO:0048588 84 0.562
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.561
positive regulation of transcription via serum response element binding GO:0010735 1 0.559
regulation of skeletal muscle fiber development GO:0048742 36 0.557
positive regulation of endothelial cell differentiation GO:0045603 7 0.553
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.550
mesoderm formation GO:0001707 62 0.546
cerebral cortex tangential migration GO:0021800 7 0.546
nephron epithelium morphogenesis GO:0072088 68 0.544
negative regulation of chondrocyte differentiation GO:0032331 13 0.542
Mouse
regulation of endothelial cell differentiation GO:0045601 10 0.533
Mouse
chemotaxis GO:0006935 247 0.530
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.529
regulation of cellular component size GO:0032535 121 0.527
Mouse
vascular process in circulatory system GO:0003018 62 0.527
Mouse
lateral mesodermal cell fate specification GO:0048377 2 0.527
Mouse
regulation of endothelial cell proliferation GO:0001936 23 0.527
Mouse
regulation of map kinase activity GO:0043405 120 0.527
neuroblast proliferation GO:0007405 49 0.526
regulation of intracellular transport GO:0032386 159 0.526
leukocyte differentiation GO:0002521 342 0.522
Mouse
artery smooth muscle contraction GO:0014824 2 0.513
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.512
Mouse
response to organic cyclic compound GO:0014070 198 0.511
Mouse Rat
epithelial tube formation GO:0072175 130 0.510
insulin secretion GO:0030073 89 0.509
Mouse
ventricular cardiac myofibril assembly GO:0055005 3 0.505
neuron migration GO:0001764 122 0.505
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.504
Fly
central nervous system vasculogenesis GO:0022009 3 0.504
mesenchymal cell proliferation involved in ureteric bud development GO:0072138 3 0.503
corticotropin hormone secreting cell differentiation GO:0060128 3 0.503
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.502
paraxial mesoderm morphogenesis GO:0048340 10 0.501
Mouse
regulation of proteolysis GO:0030162 164 0.500
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.499
rhythmic process GO:0048511 174 0.499
Mouse
nephrogenic mesenchyme development GO:0072076 3 0.497
regulation of ketone biosynthetic process GO:0010566 2 0.496
gliogenesis GO:0042063 141 0.493
regulation of cardiac muscle tissue development GO:0055024 31 0.492
myotube differentiation GO:0014902 105 0.491
positive regulation of nervous system development GO:0051962 221 0.490
Mouse Fly
mesoderm development GO:0007498 100 0.490
sinoatrial node cell differentiation GO:0060921 3 0.489
negative regulation of prostatic bud formation GO:0060686 4 0.488
ureteric bud development GO:0001657 94 0.485
development of primary male sexual characteristics GO:0046546 88 0.484
Mouse
midgut development GO:0007494 4 0.482
ear development GO:0043583 200 0.480
pigmentation GO:0043473 71 0.479
cerebellum vasculature morphogenesis GO:0061301 1 0.477
metanephros development GO:0001656 79 0.476
positive regulation of epithelial cell proliferation GO:0050679 68 0.474
Mouse
positive regulation of wnt signaling pathway GO:0030177 45 0.471
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.470
morphogenesis of embryonic epithelium GO:0016331 159 0.470
positive regulation of protein kinase activity GO:0045860 144 0.466
Mouse
regulation of anatomical structure size GO:0090066 178 0.463
Mouse
ovulation cycle GO:0042698 59 0.460
Mouse
regulation of hydrolase activity GO:0051336 246 0.460
positive regulation of endothelial cell proliferation GO:0001938 17 0.459
Mouse
negative regulation of endodermal cell differentiation GO:1903225 1 0.458
cardiac ventricle development GO:0003231 83 0.457
positive regulation of dna templated transcription elongation GO:0032786 2 0.456
muscle cell development GO:0055001 133 0.454
hair follicle development GO:0001942 85 0.454
Mouse
positive regulation of biomineral tissue development GO:0070169 12 0.453
Human
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.452
extrinsic apoptotic signaling pathway GO:0097191 126 0.451
Human Mouse
response to dietary excess GO:0002021 18 0.450
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.450
neuropilin signaling pathway GO:0038189 2 0.449
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.448
Human Fly
cardiac chamber development GO:0003205 108 0.448
Human
epidermis development GO:0008544 187 0.446
Mouse
b cell tolerance induction GO:0002514 2 0.446
Mouse
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.442
angiogenesis GO:0001525 201 0.440
positive regulation of axon guidance GO:1902669 5 0.437
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.432
Mouse
regulation of phospholipase c activity GO:1900274 3 0.432
cerebellum development GO:0021549 77 0.431
regulation of striated muscle cell differentiation GO:0051153 81 0.431
cell proliferation in midbrain GO:0033278 2 0.429
muscle cell differentiation GO:0042692 261 0.428
neuroepithelial cell differentiation GO:0060563 37 0.425
mesenchyme morphogenesis GO:0072132 32 0.422
Mouse
pigment cell differentiation GO:0050931 27 0.422
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.422
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.421
cell proliferation involved in kidney development GO:0072111 14 0.418
endocardial cushion development GO:0003197 26 0.417
Human Mouse
positive regulation of p38mapk cascade GO:1900745 1 0.416
medulla oblongata development GO:0021550 3 0.414
cell type specific apoptotic process GO:0097285 268 0.413
Mouse
regulation of cardioblast differentiation GO:0051890 3 0.411
stem cell maintenance GO:0019827 130 0.409
Mouse Fly
hair cycle GO:0042633 90 0.409
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.409
Mouse
myeloid leukocyte activation GO:0002274 83 0.409
Mouse
nucleus accumbens development GO:0021768 1 0.405
sensory organ morphogenesis GO:0090596 242 0.405
vasoconstriction GO:0042310 27 0.401
Mouse
lens development in camera type eye GO:0002088 62 0.400
Mouse
muscle cell migration GO:0014812 19 0.398
vegf activated neuropilin signaling pathway GO:0038190 2 0.397
semaphorin plexin signaling pathway GO:0071526 21 0.397
metanephric glomerular endothelium development GO:0072264 1 0.396
paraxial mesoderm development GO:0048339 18 0.395
Mouse
semicircular canal formation GO:0060876 1 0.395
negative regulation of cell fate specification GO:0009996 4 0.395
regulation of cell substrate adhesion GO:0010810 73 0.395
maintenance of protein location in nucleus GO:0051457 2 0.394
Worm
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.391
branchiomotor neuron axon guidance GO:0021785 7 0.390
forebrain neuron differentiation GO:0021879 52 0.388
cell migration involved in gastrulation GO:0042074 13 0.387
neural tube development GO:0021915 160 0.387
cerebral cortex cell migration GO:0021795 44 0.385
anti mullerian hormone signaling pathway GO:1990262 1 0.382
Mouse
forebrain cell migration GO:0021885 58 0.381
cerebellar granule cell precursor tangential migration GO:0021935 1 0.380
regulation of myoblast differentiation GO:0045661 29 0.379
formation of radial glial scaffolds GO:0021943 4 0.377
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.375
Fly
autonomic nervous system development GO:0048483 43 0.375
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.374
development of primary female sexual characteristics GO:0046545 73 0.373
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.372
Mouse
positive regulation of cell development GO:0010720 237 0.372
Mouse
negative regulation of growth GO:0045926 99 0.372
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.371
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.370
regulation of protein targeting GO:1903533 61 0.369
cellular ketone metabolic process GO:0042180 84 0.368
regulation of binding GO:0051098 111 0.368
Mouse
positive regulation of programmed cell death GO:0043068 218 0.364
Mouse
filopodium assembly GO:0046847 19 0.364
Mouse
lung development GO:0030324 164 0.361
Mouse
negative regulation of cardiac muscle tissue development GO:0055026 8 0.361
peptide hormone secretion GO:0030072 109 0.360
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.358
Mouse
cardiac muscle cell development GO:0055013 39 0.354
otolith morphogenesis GO:0032474 3 0.352
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.350
Mouse
cell cell junction organization GO:0045216 72 0.349
protein import into nucleus GO:0006606 95 0.346
central nervous system neuron development GO:0021954 67 0.346
regulation of tolerance induction GO:0002643 10 0.345
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.342
olfactory lobe development GO:0021988 32 0.341
stress activated mapk cascade GO:0051403 80 0.341
muscular septum morphogenesis GO:0003150 4 0.339
regulation of embryonic development GO:0045995 71 0.338
Mouse
specification of organ identity GO:0010092 30 0.338
cell substrate adhesion GO:0031589 130 0.336
carbohydrate homeostasis GO:0033500 128 0.331
myeloid cell homeostasis GO:0002262 114 0.331
endochondral bone growth GO:0003416 19 0.331
Mouse
fat cell differentiation GO:0045444 160 0.330
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.329
establishment of protein localization to organelle GO:0072594 118 0.328
cardiac muscle fiber development GO:0048739 4 0.328
cell chemotaxis GO:0060326 81 0.327
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.326
primary neural tube formation GO:0014020 95 0.325
tissue migration GO:0090130 68 0.325
Mouse
regulation of blood vessel size GO:0050880 56 0.321
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.320
outflow tract morphogenesis GO:0003151 53 0.319
odontogenesis GO:0042476 78 0.319
Mouse
locomotory behavior GO:0007626 195 0.318
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.313
negative regulation of gliogenesis GO:0014014 23 0.312
heart induction GO:0003129 2 0.312
activation of mapk activity GO:0000187 59 0.310
regulation of pathway restricted smad protein phosphorylation GO:0060393 6 0.308
Human
mesodermal cell fate commitment GO:0001710 17 0.306
Mouse
hippocampus development GO:0021766 52 0.305
glomerular mesangial cell development GO:0072144 3 0.305
rho protein signal transduction GO:0007266 32 0.304
glial cell differentiation GO:0010001 131 0.304
protein localization to endosome GO:0036010 2 0.302
developmental pigmentation GO:0048066 40 0.302
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.300
regulation of response to wounding GO:1903034 189 0.299
response to oxygen levels GO:0070482 62 0.298
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.298
negative regulation of insulin secretion GO:0046676 14 0.297
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.296
nephron morphogenesis GO:0072028 69 0.295
positive regulation of dendrite development GO:1900006 21 0.295
telencephalon cell migration GO:0022029 55 0.295
regulation of epithelial to mesenchymal transition GO:0010717 22 0.295
regulation of epithelial cell migration GO:0010632 35 0.295
Mouse

Acvr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.610
disease of anatomical entity DOID:7 0 0.610
Human
cardiovascular system disease DOID:1287 0 0.610
cancer DOID:162 0 0.400
disease of cellular proliferation DOID:14566 0 0.400