|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.342
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.329
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.267
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.258
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.180
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.178
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.176
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.161
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.145
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.136
|
Zebrafish |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.132
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.130
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.128
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.128
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.124
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.119
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.116
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.115
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.114
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.112
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.111
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.109
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.104
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.095
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.095
|
Mouse |
|
|
sensory perception
|
GO:0007600 |
245 |
0.094
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.094
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.091
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.090
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.087
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.084
|
Mouse |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.083
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.083
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.083
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.081
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.080
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.080
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.080
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.079
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.079
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.076
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.076
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.074
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.073
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.072
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.070
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.070
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.070
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.070
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.069
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.069
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.068
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.067
|
|
|
|
positive regulation of dopamine secretion
|
GO:0033603 |
2 |
0.066
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.065
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.065
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.063
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.063
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.063
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.060
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.059
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.058
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.058
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.058
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.057
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.057
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.055
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.054
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.054
|
Mouse |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.054
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.054
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.053
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.052
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.051
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.050
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.050
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.049
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.049
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.049
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.048
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.048
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.048
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.048
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.047
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.047
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
71 |
0.046
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.046
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.046
|
Human |
|
|
ossification
|
GO:0001503 |
216 |
0.046
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.046
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.046
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.046
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.045
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.045
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.045
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.045
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.044
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.044
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.044
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.043
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.043
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.043
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.042
|
Zebrafish |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.042
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.042
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.041
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.041
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.041
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.040
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.040
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.040
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.040
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.040
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.039
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.039
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.039
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.039
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.039
|
|
|
|
response to pain
|
GO:0048265 |
26 |
0.038
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.038
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.038
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.037
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.037
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.037
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.037
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.036
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.036
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.036
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.036
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.036
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.035
|
|
|
|
somatotropin secreting cell differentiation
|
GO:0060126 |
4 |
0.035
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.035
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.035
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.035
|
|
|
|
pituitary gland development
|
GO:0021983 |
38 |
0.035
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.034
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
3 |
0.034
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.034
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.034
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.033
|
Human |
|
|
membrane organization
|
GO:0061024 |
245 |
0.033
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.033
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.033
|
Human Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.033
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.033
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.033
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.032
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.032
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.032
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.031
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.031
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.031
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.031
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.031
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.031
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.031
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.030
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
136 |
0.030
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.030
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.030
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.030
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.030
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.030
|
|
|
|
learning
|
GO:0007612 |
98 |
0.029
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.029
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.029
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.029
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.029
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.029
|
Mouse |
|
|
memory
|
GO:0007613 |
58 |
0.029
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
49 |
0.029
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.029
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.029
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.029
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.028
|
Mouse |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.028
|
|
|
|
regulation of acetylcholine secretion neurotransmission
|
GO:0014056 |
2 |
0.028
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.028
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.028
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.028
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.028
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.028
|
Mouse |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.028
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.027
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.027
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.027
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.027
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.027
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.027
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.027
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.026
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.026
|
Zebrafish |
|
|
wound healing
|
GO:0042060 |
157 |
0.026
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.026
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.026
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.026
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.026
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.026
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.026
|
Mouse |
|
|
kidney development
|
GO:0001822 |
213 |
0.026
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.026
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.026
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.026
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.025
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.025
|
Mouse |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.025
|
Zebrafish |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.025
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.025
|
|
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.025
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.025
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.025
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.025
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.025
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.025
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.025
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.025
|
Mouse |
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.025
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.025
|
|
|
|
acetylcholine secretion neurotransmission
|
GO:0014055 |
2 |
0.025
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.024
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.024
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.024
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.024
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.024
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.024
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.024
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.024
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.024
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.024
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.023
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.023
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.023
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.023
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.023
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.023
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.023
|
Human |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.023
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.023
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.023
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.023
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.023
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.023
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.023
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.023
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.022
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.022
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.022
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.022
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.022
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.022
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.022
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.022
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.022
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.022
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.022
|
Human Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.022
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.022
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.022
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.021
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.021
|
Mouse |
|
|
peptide transport
|
GO:0015833 |
133 |
0.021
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.021
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.021
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.021
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.021
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.021
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.021
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.021
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.021
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.021
|
|
|
|
sperm motility
|
GO:0030317 |
47 |
0.021
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.021
|
Zebrafish |
|
|
lung development
|
GO:0030324 |
164 |
0.021
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.021
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.020
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.020
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.020
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.020
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.020
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.020
|
Human |
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.020
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.020
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
53 |
0.020
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.020
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.020
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.020
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.020
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.020
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.020
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.019
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.019
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.019
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.019
|
Mouse |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.019
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.019
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.019
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.019
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.019
|
|
|
|
urinary bladder smooth muscle contraction
|
GO:0014832 |
5 |
0.019
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.019
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.019
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.019
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.019
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.019
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.019
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.019
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.019
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.019
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.019
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.019
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.019
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.018
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.018
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.018
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.018
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.018
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.018
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.018
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.018
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.018
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.018
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.018
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.018
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.018
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.018
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.018
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.018
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.018
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.018
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.018
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.017
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.017
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.017
|
|
|
|
inner ear receptor cell development
|
GO:0060119 |
39 |
0.017
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.017
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.017
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.017
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.017
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.017
|
Mouse |
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.017
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.017
|
Mouse |
|
|
telencephalon development
|
GO:0021537 |
186 |
0.017
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.017
|
Human Mouse |
|
|
response to insulin
|
GO:0032868 |
100 |
0.017
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.017
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.017
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.017
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.017
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.017
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.017
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.017
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.017
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.017
|
|
|
|
regulation of action potential
|
GO:0098900 |
4 |
0.017
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.017
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.017
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.017
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.016
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.016
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.016
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.016
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.016
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.016
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.016
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.016
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.016
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.016
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.016
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.016
|
Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.016
|
Mouse |
|
|
nephron development
|
GO:0072006 |
109 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.016
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.016
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.016
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.016
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.016
|
|
|
|
regulation of circadian sleep wake cycle rem sleep
|
GO:0042320 |
1 |
0.016
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.016
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.015
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.015
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.015
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.015
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.015
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.015
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.015
|
|
|
|
spinal cord motor neuron differentiation
|
GO:0021522 |
35 |
0.015
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.015
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.015
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.015
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
15 |
0.015
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.015
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.015
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.015
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.015
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.015
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.015
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.015
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.015
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.015
|
|
|
|
norepinephrine transport
|
GO:0015874 |
2 |
0.014
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.014
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.014
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.014
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.014
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.014
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.014
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.014
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
33 |
0.014
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.014
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.014
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.014
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.014
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.014
|
|
|
|
transepithelial chloride transport
|
GO:0030321 |
4 |
0.014
|
|
|
|
regulation of inositol phosphate biosynthetic process
|
GO:0010919 |
3 |
0.014
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.014
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.014
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.014
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.014
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.014
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.014
|
|
|
|
norepinephrine secretion
|
GO:0048243 |
2 |
0.014
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.014
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.014
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.014
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.014
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.014
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.014
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.014
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.014
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.014
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.013
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.013
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.013
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.013
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.013
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.013
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.013
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.013
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.013
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.013
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.013
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.013
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.013
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.013
|
Mouse |
|
|
positive regulation of inositol phosphate biosynthetic process
|
GO:0060732 |
2 |
0.013
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.013
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.013
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.013
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.013
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.013
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.013
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.013
|
|
|
|
neurological system process involved in regulation of systemic arterial blood pressure
|
GO:0001976 |
18 |
0.013
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.013
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.013
|
|
|
|
excretion
|
GO:0007588 |
22 |
0.013
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.013
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.013
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.013
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.013
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.013
|
Zebrafish Mouse |
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.013
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.013
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.013
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.013
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.013
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.013
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.013
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.013
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.013
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.013
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.012
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.012
|
Mouse |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.012
|
|
|
|
smooth muscle contraction involved in micturition
|
GO:0060083 |
3 |
0.012
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.012
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.012
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.012
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.012
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.012
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.012
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.012
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.012
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.012
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.012
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.012
|
|
