Mus musculus

0 known processes

Pif1

PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)

(Aliases: AI449441,4631410M14)

Pif1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule polymerization or depolymerization GO:0031109 26 0.176
regulation of organelle organization GO:0033043 289 0.071
Human
regulation of protein kinase activity GO:0045859 232 0.056
regulation of cell cycle GO:0051726 281 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
organelle fission GO:0048285 170 0.053
microtubule polymerization GO:0046785 12 0.053
cellular amino acid metabolic process GO:0006520 103 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.049
cell fate commitment GO:0045165 210 0.047
negative regulation of protein metabolic process GO:0051248 282 0.046
macromolecule catabolic process GO:0009057 281 0.046
negative regulation of cellular component organization GO:0051129 194 0.046
organelle assembly GO:0070925 177 0.045
regulation of transferase activity GO:0051338 263 0.044
Human
amine metabolic process GO:0009308 45 0.044
organelle localization GO:0051640 179 0.044
cellular amine metabolic process GO:0044106 44 0.043
meiotic cell cycle GO:0051321 122 0.043
cellular protein complex assembly GO:0043623 116 0.043
leukocyte mediated immunity GO:0002443 174 0.043
microtubule based process GO:0007017 236 0.042
nuclear division GO:0000280 158 0.041
regulation of cellular amine metabolic process GO:0033238 20 0.041
meiotic nuclear division GO:0007126 115 0.041
protein processing GO:0016485 163 0.039
immune effector process GO:0002252 321 0.039
cellular ketone metabolic process GO:0042180 84 0.037
regulation of cell cycle process GO:0010564 160 0.036
meiosis i GO:0007127 60 0.036
b cell activation GO:0042113 161 0.035
spindle assembly involved in meiosis GO:0090306 4 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
heterocycle catabolic process GO:0046700 280 0.034
Human
establishment or maintenance of cell polarity GO:0007163 86 0.033
protein maturation GO:0051604 176 0.033
regulation of secretion GO:0051046 274 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
protein polymerization GO:0051258 57 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
dna repair GO:0006281 107 0.032
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.032
cation transport GO:0006812 399 0.032
peptidyl amino acid modification GO:0018193 336 0.031
mitotic cell cycle GO:0000278 195 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
meiotic cell cycle process GO:1903046 77 0.031
endomembrane system organization GO:0010256 147 0.030
dna metabolic process GO:0006259 303 0.030
Human
cell division GO:0051301 120 0.030
positive regulation of nuclear division GO:0051785 27 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
Human
reactive oxygen species metabolic process GO:0072593 84 0.029
microtubule nucleation GO:0007020 2 0.028
regulation of exit from mitosis GO:0007096 1 0.027
cytokine production GO:0001816 319 0.027
regulation of cytokine production GO:0001817 266 0.026
negative regulation of cell proliferation GO:0008285 296 0.025
dna recombination GO:0006310 92 0.025
chromosome segregation GO:0007059 48 0.025
protein modification by small protein conjugation GO:0032446 187 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.024
positive regulation of organelle organization GO:0010638 128 0.024
maintenance of location GO:0051235 89 0.024
negative regulation of organelle organization GO:0010639 90 0.024
protein catabolic process GO:0030163 221 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
Human
adaptive immune response GO:0002250 155 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
Human
t cell activation GO:0042110 289 0.024
positive regulation of protein modification process GO:0031401 299 0.023
establishment of organelle localization GO:0051656 122 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
Human
energy derivation by oxidation of organic compounds GO:0015980 77 0.023
lateral inhibition GO:0046331 1 0.022
negative regulation of molecular function GO:0044092 258 0.022
Human
mapk cascade GO:0000165 281 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.021
Human
apoptotic signaling pathway GO:0097190 306 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
protein ubiquitination GO:0016567 171 0.021
male gamete generation GO:0048232 285 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
mitotic cytokinesis GO:0000281 4 0.021
regulation of protein localization GO:0032880 231 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.020
Human
lymphocyte mediated immunity GO:0002449 139 0.020
leukocyte proliferation GO:0070661 172 0.020
regulation of cellular response to stress GO:0080135 159 0.020
mitotic cell cycle process GO:1903047 159 0.020
cellular lipid metabolic process GO:0044255 323 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
negative regulation of protein modification process GO:0031400 163 0.020
lymphocyte proliferation GO:0046651 164 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
Human
stem cell differentiation GO:0048863 268 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
membrane organization GO:0061024 245 0.019
spindle assembly involved in mitosis GO:0090307 4 0.019
positive regulation of mitotic cell cycle GO:0045931 41 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
Human
macromolecule methylation GO:0043414 120 0.019
regulation of adaptive immune response GO:0002819 90 0.019
regulation of response to wounding GO:1903034 189 0.019
cell adhesion GO:0007155 329 0.018
regulation of anatomical structure size GO:0090066 178 0.018
regulation of membrane potential GO:0042391 192 0.018
regulation of mitotic cell cycle phase transition GO:1901990 73 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
oxidation reduction process GO:0055114 342 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
Human
positive regulation of cell cycle process GO:0090068 61 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
regulation of cellular component size GO:0032535 121 0.018
positive regulation of cell death GO:0010942 224 0.018
muscle tissue development GO:0060537 308 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
regulation of mapk cascade GO:0043408 248 0.017
negative regulation of cell cycle GO:0045786 123 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
positive regulation of proteolysis GO:0045862 85 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
regulation of cell activation GO:0050865 289 0.017
cell type specific apoptotic process GO:0097285 268 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
multicellular organismal signaling GO:0035637 91 0.017
regulation of microtubule based process GO:0032886 52 0.017
regulation of homeostatic process GO:0032844 182 0.017
Human
glycosyl compound metabolic process GO:1901657 246 0.017
Human
lymphocyte differentiation GO:0030098 242 0.017
establishment of meiotic spindle orientation GO:0051296 1 0.016
regulation of meiotic cell cycle GO:0051445 34 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
forebrain development GO:0030900 302 0.016
organophosphate catabolic process GO:0046434 232 0.016
Human
atp metabolic process GO:0046034 75 0.016
Human
regulation of asymmetric cell division GO:0009786 4 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
metaphase plate congression GO:0051310 2 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
Human
regulation of cell division GO:0051302 76 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
Human
male meiosis GO:0007140 37 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
Human
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
regulation of cellular catabolic process GO:0031329 242 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
nucleotide metabolic process GO:0009117 332 0.015
Human
transmembrane transport GO:0055085 412 0.015
response to growth factor GO:0070848 198 0.015
aromatic compound catabolic process GO:0019439 286 0.015
Human
cellular carbohydrate metabolic process GO:0044262 119 0.015
striated muscle tissue development GO:0014706 293 0.015
stem cell development GO:0048864 219 0.015
mitochondrion organization GO:0007005 134 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
ear development GO:0043583 200 0.015
extracellular structure organization GO:0043062 148 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
Human
positive regulation of apoptotic process GO:0043065 217 0.015
nucleoside metabolic process GO:0009116 246 0.015
Human
positive regulation of protein kinase activity GO:0045860 144 0.015
divalent inorganic cation transport GO:0072511 178 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
Human
inflammatory response GO:0006954 244 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
Human
germ cell development GO:0007281 185 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
regulation of defense response GO:0031347 233 0.014
negative regulation of cytoskeleton organization GO:0051494 36 0.014
gland development GO:0048732 330 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
Human
purine ribonucleotide catabolic process GO:0009154 208 0.014
Human
purine nucleoside metabolic process GO:0042278 241 0.014
Human
positive regulation of transferase activity GO:0051347 167 0.014
leukocyte differentiation GO:0002521 342 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
Human
regulation of mitotic sister chromatid segregation GO:0033047 12 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
positive regulation of kinase activity GO:0033674 155 0.014
regulation of kinase activity GO:0043549 249 0.014
fat cell differentiation GO:0045444 160 0.014
leukocyte migration GO:0050900 124 0.014
skeletal system development GO:0001501 356 0.014
synaptic transmission GO:0007268 329 0.013
regulation of system process GO:0044057 200 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
regulation of proteolysis GO:0030162 164 0.013
oogenesis GO:0048477 56 0.013
divalent metal ion transport GO:0070838 172 0.013
protein alkylation GO:0008213 81 0.013
protein depolymerization GO:0051261 34 0.013
negative regulation of cell cycle phase transition GO:1901988 48 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
chromatin organization GO:0006325 206 0.013
transmission of nerve impulse GO:0019226 76 0.013
regulation of leukocyte mediated immunity GO:0002703 104 0.013
regulation of chromosome organization GO:0033044 83 0.013
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
Human
fertilization GO:0009566 127 0.013
regulation of nuclear division GO:0051783 56 0.013
regulation of secretion by cell GO:1903530 249 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
neuronal action potential GO:0019228 54 0.013
regulation of protein catabolic process GO:0042176 108 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
Human
actin filament organization GO:0007015 113 0.012
negative regulation of protein processing GO:0010955 79 0.012
cytoplasmic transport GO:0016482 234 0.012
sequestering of metal ion GO:0051238 19 0.012
cellular homeostasis GO:0019725 240 0.012
negative regulation of nervous system development GO:0051961 156 0.012
female gamete generation GO:0007292 74 0.012
spermatogenesis GO:0007283 284 0.012
cellular chemical homeostasis GO:0055082 215 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
response to organonitrogen compound GO:0010243 246 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
Human
cellular response to cytokine stimulus GO:0071345 189 0.012
axonogenesis GO:0007409 274 0.012
urogenital system development GO:0001655 261 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
intestinal epithelial structure maintenance GO:0060729 4 0.012
regulation of neuron differentiation GO:0045664 281 0.012
renal system development GO:0072001 225 0.012
protein localization to membrane GO:0072657 108 0.012
purine containing compound metabolic process GO:0072521 311 0.012
Human
regulation of intracellular transport GO:0032386 159 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.012
double strand break repair GO:0006302 48 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
Human
purine nucleoside catabolic process GO:0006152 205 0.012
Human
stem cell maintenance GO:0019827 130 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
chromatin modification GO:0016568 187 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
ossification GO:0001503 216 0.011
primary neural tube formation GO:0014020 95 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
carbohydrate metabolic process GO:0005975 230 0.011
rhythmic process GO:0048511 174 0.011
cellularization GO:0007349 1 0.011
negative regulation of cell size GO:0045792 3 0.011
regulation of microtubule cytoskeleton organization GO:0070507 37 0.011
intracellular protein transport GO:0006886 204 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
ras protein signal transduction GO:0007265 77 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
Human
action potential GO:0001508 78 0.011
nitrogen compound transport GO:0071705 271 0.011
neuron death GO:0070997 154 0.011
calcium ion transport GO:0006816 159 0.011
circulatory system process GO:0003013 197 0.011
alcohol metabolic process GO:0006066 116 0.011
cellular protein complex disassembly GO:0043624 36 0.011
cellular protein catabolic process GO:0044257 155 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
placenta development GO:0001890 140 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
negative regulation of cell development GO:0010721 169 0.011
neuron migration GO:0001764 122 0.011
negative regulation of immune system process GO:0002683 209 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
endocytosis GO:0006897 168 0.011
sequestering of calcium ion GO:0051208 18 0.011
oocyte construction GO:0007308 2 0.011
skeletal system morphogenesis GO:0048705 203 0.011
neuron apoptotic process GO:0051402 142 0.011
macromolecular complex disassembly GO:0032984 43 0.011
single organism cell adhesion GO:0098602 156 0.010
regulation of neuron death GO:1901214 134 0.010
positive regulation of cell development GO:0010720 237 0.010
cell cycle switching GO:0060184 1 0.010
establishment of spindle orientation GO:0051294 15 0.010
cellular ion homeostasis GO:0006873 165 0.010
protein complex disassembly GO:0043241 40 0.010
tube closure GO:0060606 91 0.010
rho protein signal transduction GO:0007266 32 0.010
anatomical structure homeostasis GO:0060249 145 0.010
Human
kidney development GO:0001822 213 0.010
regulation of protein processing GO:0070613 96 0.010
innate immune response GO:0045087 157 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
Human
negative regulation of synapse assembly GO:0051964 3 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of multi organism process GO:0043900 111 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
spindle localization GO:0051653 22 0.010
positive regulation of nervous system development GO:0051962 221 0.010
mitotic chromosome condensation GO:0007076 1 0.010
mitochondrion distribution GO:0048311 4 0.010
locomotory behavior GO:0007626 195 0.010
immunoglobulin mediated immune response GO:0016064 69 0.010
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.010
b cell differentiation GO:0030183 78 0.010
response to lipopolysaccharide GO:0032496 128 0.010

Pif1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.031
disease of anatomical entity DOID:7 0 0.031
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
hematopoietic system disease DOID:74 0 0.017
nervous system disease DOID:863 0 0.015
gastrointestinal system cancer DOID:3119 0 0.011