Mus musculus

111 known processes

Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

(Aliases: Epac1,Epac,2310016P22Rik,MGC19192,9330170P05Rik)

Rapgef3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.189
cellular amino acid metabolic process GO:0006520 103 0.136
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.126
g protein coupled receptor signaling pathway GO:0007186 243 0.125
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.120
small gtpase mediated signal transduction GO:0007264 97 0.112
Human
telencephalon development GO:0021537 186 0.092
cerebral cortex development GO:0021987 86 0.090
regulation of cellular amine metabolic process GO:0033238 20 0.090
amine metabolic process GO:0009308 45 0.084
lymphocyte differentiation GO:0030098 242 0.081
multicellular organism growth GO:0035264 161 0.081
urogenital system development GO:0001655 261 0.080
negative regulation of cellular amine metabolic process GO:0033239 1 0.080
fat cell differentiation GO:0045444 160 0.079
monosaccharide metabolic process GO:0005996 106 0.079
purine nucleotide metabolic process GO:0006163 302 0.078
transmembrane transport GO:0055085 412 0.078
regulation of actin filament based process GO:0032970 99 0.077
Human
carbohydrate metabolic process GO:0005975 230 0.076
regulation of organelle organization GO:0033043 289 0.076
Human
regulation of insulin receptor signaling pathway GO:0046626 21 0.073
purine ribonucleotide metabolic process GO:0009150 290 0.072
forebrain development GO:0030900 302 0.070
Mouse
renal system development GO:0072001 225 0.069
regulation of cell projection organization GO:0031344 206 0.067
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.065
response to organonitrogen compound GO:0010243 246 0.064
Human Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.064
cellular response to growth factor stimulus GO:0071363 197 0.064
nucleoside catabolic process GO:0009164 206 0.064
regulation of nucleoside metabolic process GO:0009118 130 0.063
regulation of transmembrane transport GO:0034762 128 0.063
regulation of cell motility GO:2000145 236 0.063
Mouse
cellular response to peptide GO:1901653 92 0.062
hexose metabolic process GO:0019318 98 0.062
glucose homeostasis GO:0042593 128 0.060
inflammatory response GO:0006954 244 0.058
ribonucleotide metabolic process GO:0009259 291 0.056
layer formation in cerebral cortex GO:0021819 13 0.055
hindbrain development GO:0030902 128 0.055
cation transport GO:0006812 399 0.055
nucleoside phosphate metabolic process GO:0006753 338 0.055
tube formation GO:0035148 140 0.054
organic cyclic compound catabolic process GO:1901361 295 0.054
cellular amine metabolic process GO:0044106 44 0.054
negative regulation of phosphorylation GO:0042326 166 0.054
negative regulation of protein metabolic process GO:0051248 282 0.052
epithelial tube formation GO:0072175 130 0.052
embryonic epithelial tube formation GO:0001838 130 0.050
cell adhesion GO:0007155 329 0.050
regulation of cellular catabolic process GO:0031329 242 0.049
gland development GO:0048732 330 0.049
organophosphate catabolic process GO:0046434 232 0.049
carbohydrate homeostasis GO:0033500 128 0.049
nucleoside triphosphate metabolic process GO:0009141 230 0.048
nucleotide catabolic process GO:0009166 217 0.048
negative regulation of molecular function GO:0044092 258 0.048
peptidyl amino acid modification GO:0018193 336 0.047
gtp metabolic process GO:0046039 144 0.047
regulation of actin cytoskeleton organization GO:0032956 84 0.047
Human
positive regulation of nervous system development GO:0051962 221 0.047
Mouse
positive regulation of cell development GO:0010720 237 0.046
Mouse
cytokine production GO:0001816 319 0.046
regulation of hydrolase activity GO:0051336 246 0.046
response to growth factor GO:0070848 198 0.046
negative regulation of cellular protein metabolic process GO:0032269 247 0.045
cellular response to peptide hormone stimulus GO:0071375 92 0.044
regulation of transferase activity GO:0051338 263 0.044
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.044
Mouse
epithelial tube morphogenesis GO:0060562 303 0.044
regulation of activation of jak2 kinase activity GO:0010534 1 0.044
regulation of protein localization GO:0032880 231 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.044
cellular response to organonitrogen compound GO:0071417 145 0.043
Human Mouse
peptidyl tyrosine modification GO:0018212 145 0.043
cellular homeostasis GO:0019725 240 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
ras protein signal transduction GO:0007265 77 0.042
Human
regulation of ras gtpase activity GO:0032318 88 0.041
Human Mouse
mapk cascade GO:0000165 281 0.040
Mouse
rho protein signal transduction GO:0007266 32 0.040
morphogenesis of embryonic epithelium GO:0016331 159 0.040
aromatic compound catabolic process GO:0019439 286 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
regulation of secretion by cell GO:1903530 249 0.039
Mouse
response to insulin GO:0032868 100 0.039
positive regulation of programmed cell death GO:0043068 218 0.039
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.038
sensory organ morphogenesis GO:0090596 242 0.038
regulation of mapk cascade GO:0043408 248 0.038
Mouse
glycosyl compound catabolic process GO:1901658 206 0.038
t cell activation GO:0042110 289 0.037
b cell activation GO:0042113 161 0.037
regulation of neuron differentiation GO:0045664 281 0.037
Mouse
leukocyte differentiation GO:0002521 342 0.037
embryonic placenta development GO:0001892 98 0.037
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.036
regulation of homeostatic process GO:0032844 182 0.036
purine ribonucleoside metabolic process GO:0046128 241 0.036
negative regulation of cell proliferation GO:0008285 296 0.036
Mouse
multicellular organismal response to stress GO:0033555 62 0.035
embryonic organ morphogenesis GO:0048562 276 0.035
respiratory system development GO:0060541 190 0.035
regulation of cytokine production GO:0001817 266 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
memory GO:0007613 58 0.035
peptidyl tyrosine phosphorylation GO:0018108 143 0.035
camera type eye development GO:0043010 266 0.035
t cell differentiation GO:0030217 174 0.034
kidney development GO:0001822 213 0.034
cellular response to insulin stimulus GO:0032869 78 0.034
nucleoside metabolic process GO:0009116 246 0.034
purine containing compound metabolic process GO:0072521 311 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
response to peptide GO:1901652 136 0.033
pallium development GO:0021543 120 0.033
oxidation reduction process GO:0055114 342 0.033
positive regulation of neuron differentiation GO:0045666 141 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
glucose metabolic process GO:0006006 92 0.032
regulation of lymphocyte differentiation GO:0045619 107 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
immune effector process GO:0002252 321 0.032
positive regulation of protein modification process GO:0031401 299 0.032
Mouse
cognition GO:0050890 149 0.031
purine nucleotide catabolic process GO:0006195 211 0.031
positive regulation of organelle organization GO:0010638 128 0.031
Human
divalent inorganic cation transport GO:0072511 178 0.030
leukocyte activation involved in immune response GO:0002366 126 0.030
positive regulation of gtpase activity GO:0043547 85 0.030
response to amino acid GO:0043200 37 0.030
morphogenesis of a branching structure GO:0001763 203 0.030
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.030
protein ubiquitination GO:0016567 171 0.030
cellular carbohydrate metabolic process GO:0044262 119 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
cytoplasmic transport GO:0016482 234 0.030
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.030
response to acid chemical GO:0001101 111 0.030
ribonucleotide catabolic process GO:0009261 208 0.029
neuropeptide signaling pathway GO:0007218 19 0.029
Mouse
regulation of lymphocyte activation GO:0051249 240 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
guanosine containing compound catabolic process GO:1901069 144 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
Mouse
insulin receptor signaling pathway GO:0008286 49 0.029
peptide transport GO:0015833 133 0.028
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
synaptic transmission GO:0007268 329 0.027
spermatid differentiation GO:0048515 115 0.027
regulation of defense response GO:0031347 233 0.027
placenta development GO:0001890 140 0.027
divalent metal ion transport GO:0070838 172 0.027
activation of janus kinase activity GO:0042976 2 0.027
cerebral cortex radially oriented cell migration GO:0021799 31 0.027
amide transport GO:0042886 138 0.026
Mouse
adult behavior GO:0030534 135 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
heterocycle catabolic process GO:0046700 280 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
positive regulation of gtp catabolic process GO:0033126 85 0.026
cellular lipid metabolic process GO:0044255 323 0.026
positive regulation of nucleoside metabolic process GO:0045979 91 0.025
regulation of t cell activation GO:0050863 170 0.025
positive regulation of leukocyte differentiation GO:1902107 86 0.025
regulation of cytoskeleton organization GO:0051493 122 0.025
Human
adaptive immune response GO:0002250 155 0.025
regulation of ion transmembrane transport GO:0034765 119 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
nephron development GO:0072006 109 0.024
muscle cell differentiation GO:0042692 261 0.024
leukocyte mediated immunity GO:0002443 174 0.024
regulation of vasculature development GO:1901342 88 0.024
Human Mouse
male gamete generation GO:0048232 285 0.024
purine containing compound catabolic process GO:0072523 213 0.024
leukocyte migration GO:0050900 124 0.024
angiogenesis GO:0001525 201 0.024
Human
regulation of cell cycle GO:0051726 281 0.024
negative regulation of protein modification process GO:0031400 163 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
Mouse
epithelial cell development GO:0002064 159 0.023
Human
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
generation of precursor metabolites and energy GO:0006091 103 0.023
blood vessel morphogenesis GO:0048514 285 0.023
Human Mouse
regulation of secretion GO:0051046 274 0.023
Mouse
sensory perception GO:0007600 245 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
Human
response to peptide hormone GO:0043434 127 0.023
connective tissue development GO:0061448 179 0.023
neural tube formation GO:0001841 108 0.023
jak stat cascade GO:0007259 42 0.023
actin cytoskeleton organization GO:0030036 220 0.023
Human
digestive system development GO:0055123 200 0.022
cerebral cortex radial glia guided migration GO:0021801 17 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
regulation of hormone levels GO:0010817 211 0.022
Mouse
learning or memory GO:0007611 148 0.022
ion transmembrane transport GO:0034220 361 0.022
nucleotide metabolic process GO:0009117 332 0.022
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.022
negative regulation of immune system process GO:0002683 209 0.022
insulin secretion GO:0030073 89 0.022
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
muscle tissue development GO:0060537 308 0.022
nitrogen compound transport GO:0071705 271 0.021
Mouse
regulation of anatomical structure size GO:0090066 178 0.021
cell activation involved in immune response GO:0002263 126 0.021
cellular chemical homeostasis GO:0055082 215 0.021
regulation of carbohydrate metabolic process GO:0006109 75 0.021
neuron death GO:0070997 154 0.021
rhythmic process GO:0048511 174 0.021
sequestering of metal ion GO:0051238 19 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
lipid transport GO:0006869 98 0.021
regulation of activation of janus kinase activity GO:0010533 1 0.021
regulation of cell activation GO:0050865 289 0.020
carbohydrate biosynthetic process GO:0016051 74 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
positive regulation of kinase activity GO:0033674 155 0.020
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
stem cell differentiation GO:0048863 268 0.020
energy derivation by oxidation of organic compounds GO:0015980 77 0.020
cellular response to acid chemical GO:0071229 68 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
apoptotic signaling pathway GO:0097190 306 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
Mouse
organelle localization GO:0051640 179 0.020
organelle fission GO:0048285 170 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.020
digestive tract development GO:0048565 190 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.019
lipid localization GO:0010876 126 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
positive regulation of lymphocyte activation GO:0051251 140 0.019
calcium ion transport GO:0006816 159 0.019
exocytosis GO:0006887 121 0.019
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.019
Human Mouse
cellular response to hormone stimulus GO:0032870 150 0.019
leukocyte proliferation GO:0070661 172 0.019
glomerulus development GO:0032835 40 0.019
skeletal system development GO:0001501 356 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
cellular ion homeostasis GO:0006873 165 0.019
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.019
regulation of cell cycle process GO:0010564 160 0.019
eye photoreceptor cell differentiation GO:0001754 41 0.019
primary neural tube formation GO:0014020 95 0.019
inorganic cation transmembrane transport GO:0098662 207 0.018
alpha beta t cell differentiation GO:0046632 69 0.018
inner ear morphogenesis GO:0042472 101 0.018
anatomical structure homeostasis GO:0060249 145 0.018
regulation of ion transport GO:0043269 215 0.018
positive regulation of t cell activation GO:0050870 101 0.018
regulation of kinase activity GO:0043549 249 0.018
Mouse
cellular response to lipid GO:0071396 145 0.018
glycerolipid metabolic process GO:0046486 122 0.018
body fluid secretion GO:0007589 53 0.018
sequestering of calcium ion GO:0051208 18 0.018
positive regulation of cell cycle GO:0045787 92 0.018
regulation of intracellular transport GO:0032386 159 0.018
nuclear division GO:0000280 158 0.018
regionalization GO:0003002 337 0.018
kidney epithelium development GO:0072073 121 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
neural tube development GO:0021915 160 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
gtp catabolic process GO:0006184 143 0.018
respiratory tube development GO:0030323 167 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.018
regulation of carbohydrate biosynthetic process GO:0043255 40 0.018
neural tube closure GO:0001843 90 0.018
maintenance of location GO:0051235 89 0.018
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.017
tube closure GO:0060606 91 0.017
lung development GO:0030324 164 0.017
tissue homeostasis GO:0001894 115 0.017
regulation of neuron projection development GO:0010975 169 0.017
Mouse
germ cell development GO:0007281 185 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.017
regulation of response to wounding GO:1903034 189 0.017
regulation of transporter activity GO:0032409 57 0.017
negative regulation of cell migration GO:0030336 59 0.017
myotube differentiation GO:0014902 105 0.017
response to organic cyclic compound GO:0014070 198 0.017
Human Mouse
single organism cell adhesion GO:0098602 156 0.017
ossification GO:0001503 216 0.017
regulation of b cell activation GO:0050864 81 0.017
mitochondrion organization GO:0007005 134 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
regulation of generation of precursor metabolites and energy GO:0043467 38 0.017
developmental maturation GO:0021700 193 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
bone development GO:0060348 120 0.016
striated muscle tissue development GO:0014706 293 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
cell type specific apoptotic process GO:0097285 268 0.016
Mouse
mitotic cell cycle GO:0000278 195 0.016
negative regulation of cell motility GO:2000146 61 0.016
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.016
negative regulation of organelle organization GO:0010639 90 0.016
cation transmembrane transport GO:0098655 266 0.016
regulation of fat cell differentiation GO:0045598 81 0.016
stem cell development GO:0048864 219 0.016
response to oxygen levels GO:0070482 62 0.016
regulation of circadian rhythm GO:0042752 58 0.016
cardiac chamber development GO:0003205 108 0.016
cd4 positive alpha beta t cell activation GO:0035710 45 0.016
axonogenesis GO:0007409 274 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
Human Mouse
protein processing GO:0016485 163 0.016
regulation of jak stat cascade GO:0046425 34 0.016
regulation of ion transmembrane transporter activity GO:0032412 54 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016
morphogenesis of a polarized epithelium GO:0001738 37 0.016
regulation of feeding behavior GO:0060259 3 0.016
mesonephric tubule development GO:0072164 94 0.016
cerebral cortex cell migration GO:0021795 44 0.015
locomotory behavior GO:0007626 195 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
asymmetric stem cell division GO:0098722 3 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
heart morphogenesis GO:0003007 178 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.015
regulation of cell migration GO:0030334 219 0.015
Mouse
regulation of establishment of protein localization GO:0070201 181 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
regulation of glucose metabolic process GO:0010906 60 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
regulation of alpha beta t cell differentiation GO:0046637 35 0.015
hormone metabolic process GO:0042445 86 0.015
epidermis development GO:0008544 187 0.015
spongiotrophoblast layer development GO:0060712 15 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
mitral valve morphogenesis GO:0003183 4 0.015
regulation of protein kinase activity GO:0045859 232 0.015
Mouse
neural precursor cell proliferation GO:0061351 121 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
blood circulation GO:0008015 195 0.015
skin development GO:0043588 220 0.015
bmp signaling pathway GO:0030509 93 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
neuron apoptotic process GO:0051402 142 0.015
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.014
regulation of synaptic plasticity GO:0048167 87 0.014
cell growth GO:0016049 130 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
positive regulation of cell activation GO:0050867 158 0.014
positive regulation of immune effector process GO:0002699 107 0.014
regulation of protein transport GO:0051223 163 0.014
calcium ion transport into cytosol GO:0060402 48 0.014
actin filament organization GO:0007015 113 0.014
Human
dendrite development GO:0016358 115 0.014
Mouse
regulation of adaptive immune response GO:0002819 90 0.014
wnt signaling pathway GO:0016055 188 0.014
negative regulation of kinase activity GO:0033673 81 0.014
homeostasis of number of cells GO:0048872 210 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
fear response GO:0042596 33 0.014
regulation of gluconeogenesis GO:0006111 30 0.014
vesicle localization GO:0051648 86 0.014
endocrine system development GO:0035270 98 0.014
metencephalon development GO:0022037 89 0.014
nuclear transport GO:0051169 139 0.014
epidermal growth factor receptor signaling pathway GO:0007173 28 0.014
cell division GO:0051301 120 0.014
gliogenesis GO:0042063 141 0.014
plasma membrane organization GO:0007009 90 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
positive regulation of growth GO:0045927 104 0.014
membrane organization GO:0061024 245 0.014
regulation of cellular response to stress GO:0080135 159 0.014
t cell activation involved in immune response GO:0002286 43 0.014
cardiac ventricle development GO:0003231 83 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
pancreas development GO:0031016 57 0.014
regulation of cellular response to insulin stimulus GO:1900076 30 0.014
negative regulation of tyrosine phosphorylation of stat protein GO:0042532 3 0.014
positive regulation of cell death GO:0010942 224 0.014
Mouse
positive regulation of myeloid cell differentiation GO:0045639 43 0.014
carboxylic acid catabolic process GO:0046395 51 0.014
cell differentiation in spinal cord GO:0021515 53 0.013
telencephalon cell migration GO:0022029 55 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
mammary gland lobule development GO:0061377 22 0.013
positive regulation of smooth muscle cell migration GO:0014911 4 0.013
intracellular protein transport GO:0006886 204 0.013
spermatogenesis GO:0007283 284 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
Mouse
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
positive regulation of adaptive immune response GO:0002821 61 0.013
peptide hormone secretion GO:0030072 109 0.013
Mouse
response to radiation GO:0009314 165 0.013
cyclic nucleotide metabolic process GO:0009187 59 0.013
protein catabolic process GO:0030163 221 0.013
regulation of receptor activity GO:0010469 41 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
Human
inorganic ion transmembrane transport GO:0098660 234 0.013
positive regulation of t cell differentiation GO:0045582 52 0.013
meiotic nuclear division GO:0007126 115 0.013
response to inorganic substance GO:0010035 96 0.013
protein targeting GO:0006605 143 0.013
regulation of hormone secretion GO:0046883 88 0.013
circadian rhythm GO:0007623 114 0.013
positive regulation of transferase activity GO:0051347 167 0.013
Mouse
lactation GO:0007595 25 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
macromolecule catabolic process GO:0009057 281 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
syncytium formation by plasma membrane fusion GO:0000768 42 0.013
peptide secretion GO:0002790 114 0.013
Mouse
b cell differentiation GO:0030183 78 0.012
regulation of rho gtpase activity GO:0032319 58 0.012
t cell proliferation GO:0042098 120 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
phospholipid metabolic process GO:0006644 87 0.012
dephosphorylation GO:0016311 129 0.012
metal ion homeostasis GO:0055065 189 0.012
regulation of peptide transport GO:0090087 91 0.012
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.012
cerebellum development GO:0021549 77 0.012
second messenger mediated signaling GO:0019932 73 0.012
Mouse
negative regulation of cytoskeleton organization GO:0051494 36 0.012
protein localization to organelle GO:0033365 185 0.012
negative regulation of transferase activity GO:0051348 85 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
leukocyte chemotaxis GO:0030595 69 0.012
development of primary sexual characteristics GO:0045137 143 0.012
feeding behavior GO:0007631 62 0.012
neuron migration GO:0001764 122 0.012
Mouse
polysaccharide metabolic process GO:0005976 39 0.012
regulation of angiogenesis GO:0045765 81 0.012
Human
positive regulation of rho gtpase activity GO:0032321 41 0.012
regulation of metal ion transport GO:0010959 106 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
response to nutrient levels GO:0031667 109 0.012
regulation of hippo signaling GO:0035330 1 0.012
epithelial cell proliferation GO:0050673 174 0.012
ear development GO:0043583 200 0.012
endocytosis GO:0006897 168 0.012
metanephros development GO:0001656 79 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
chromatin modification GO:0016568 187 0.012
tyrosine phosphorylation of stat protein GO:0007260 23 0.012
response to transforming growth factor beta GO:0071559 88 0.012
negative regulation of cell development GO:0010721 169 0.012
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.012
negative regulation of nervous system development GO:0051961 156 0.012
Mouse
negative regulation of ossification GO:0030279 49 0.012
myeloid cell homeostasis GO:0002262 114 0.012
defecation GO:0030421 1 0.012
retina development in camera type eye GO:0060041 119 0.012
chondrocyte differentiation GO:0002062 72 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.011
cation homeostasis GO:0055080 212 0.011
lymphocyte proliferation GO:0046651 164 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
ear morphogenesis GO:0042471 118 0.011
actin filament polymerization GO:0030041 44 0.011
cellular response to inorganic substance GO:0071241 37 0.011
diencephalon development GO:0021536 63 0.011
appendage morphogenesis GO:0035107 149 0.011
skeletal muscle organ development GO:0060538 163 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
Mouse
cellular protein complex assembly GO:0043623 116 0.011
mitotic cytokinesis GO:0000281 4 0.011

Rapgef3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.017
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.012