Mus musculus

0 known processes

Lingo3

leucine rich repeat and Ig domain containing 3

(Aliases: LERN2,AI851712)

Lingo3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.311
cation transmembrane transport GO:0098655 266 0.233
transmembrane transport GO:0055085 412 0.230
cation transport GO:0006812 399 0.226
inorganic ion transmembrane transport GO:0098660 234 0.223
inorganic cation transmembrane transport GO:0098662 207 0.209
synaptic transmission GO:0007268 329 0.162
sodium ion transport GO:0006814 73 0.140
locomotory behavior GO:0007626 195 0.136
cognition GO:0050890 149 0.098
divalent metal ion transport GO:0070838 172 0.073
regulation of ion transport GO:0043269 215 0.068
conditioned taste aversion GO:0001661 4 0.058
purine nucleotide metabolic process GO:0006163 302 0.058
regulation of ion transmembrane transport GO:0034765 119 0.056
learning or memory GO:0007611 148 0.054
memory GO:0007613 58 0.051
cellular amino acid metabolic process GO:0006520 103 0.049
regulation of transmembrane transport GO:0034762 128 0.047
regulation of synaptic plasticity GO:0048167 87 0.044
negative regulation of nervous system development GO:0051961 156 0.044
Mouse
connective tissue development GO:0061448 179 0.043
regulation of membrane potential GO:0042391 192 0.043
membrane organization GO:0061024 245 0.039
negative regulation of molecular function GO:0044092 258 0.038
cellular homeostasis GO:0019725 240 0.038
forebrain development GO:0030900 302 0.038
cytoplasmic transport GO:0016482 234 0.037
negative regulation of cell proliferation GO:0008285 296 0.037
circulatory system process GO:0003013 197 0.037
regulation of system process GO:0044057 200 0.035
skeletal system morphogenesis GO:0048705 203 0.035
regulation of secretion GO:0051046 274 0.034
cellular amine metabolic process GO:0044106 44 0.034
muscle cell differentiation GO:0042692 261 0.033
eye photoreceptor cell differentiation GO:0001754 41 0.033
neuron neuron synaptic transmission GO:0007270 69 0.033
regulation of receptor activity GO:0010469 41 0.033
renal system development GO:0072001 225 0.032
anion transport GO:0006820 177 0.032
multicellular organismal signaling GO:0035637 91 0.032
divalent inorganic cation transport GO:0072511 178 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
morphogenesis of a branching structure GO:0001763 203 0.031
cellular lipid metabolic process GO:0044255 323 0.031
regulation of metal ion transport GO:0010959 106 0.031
nitrogen compound transport GO:0071705 271 0.030
stem cell differentiation GO:0048863 268 0.030
regionalization GO:0003002 337 0.030
camera type eye development GO:0043010 266 0.030
skeletal muscle organ development GO:0060538 163 0.030
positive regulation of cell development GO:0010720 237 0.029
sensory organ morphogenesis GO:0090596 242 0.029
organic cyclic compound catabolic process GO:1901361 295 0.028
skeletal system development GO:0001501 356 0.028
cell fate commitment GO:0045165 210 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
regulation of protein localization GO:0032880 231 0.028
regulation of kinase activity GO:0043549 249 0.028
peptidyl amino acid modification GO:0018193 336 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
bone development GO:0060348 120 0.027
calcium ion transport GO:0006816 159 0.027
intracellular protein transport GO:0006886 204 0.027
muscle tissue development GO:0060537 308 0.027
chemotaxis GO:0006935 247 0.027
response to organonitrogen compound GO:0010243 246 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
negative regulation of cellular amine metabolic process GO:0033239 1 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
spermatogenesis GO:0007283 284 0.026
adult locomotory behavior GO:0008344 91 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
sodium ion transmembrane transport GO:0035725 49 0.026
ras protein signal transduction GO:0007265 77 0.026
response to organic cyclic compound GO:0014070 198 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
neuron migration GO:0001764 122 0.025
calcium ion transmembrane transport GO:0070588 85 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
oxidation reduction process GO:0055114 342 0.024
amine metabolic process GO:0009308 45 0.024
regulation of neuron differentiation GO:0045664 281 0.024
protein localization to organelle GO:0033365 185 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
striated muscle tissue development GO:0014706 293 0.024
skin development GO:0043588 220 0.024
nucleotide metabolic process GO:0009117 332 0.024
glycoprotein metabolic process GO:0009100 116 0.024
regulation of neuronal synaptic plasticity GO:0048168 30 0.024
apoptotic signaling pathway GO:0097190 306 0.024
heterocycle catabolic process GO:0046700 280 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
adult behavior GO:0030534 135 0.023
developmental growth involved in morphogenesis GO:0060560 138 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
learning GO:0007612 98 0.023
epithelial cell proliferation GO:0050673 174 0.023
protein ubiquitination GO:0016567 171 0.022
positive regulation of neuron differentiation GO:0045666 141 0.022
male gamete generation GO:0048232 285 0.022
cartilage development GO:0051216 140 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
extracellular matrix organization GO:0030198 147 0.022
cation homeostasis GO:0055080 212 0.022
associative learning GO:0008306 61 0.022
transmission of nerve impulse GO:0019226 76 0.022
cellular ketone metabolic process GO:0042180 84 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
mapk cascade GO:0000165 281 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
Mouse
gonad development GO:0008406 141 0.021
retina development in camera type eye GO:0060041 119 0.021
gland development GO:0048732 330 0.021
macromolecule catabolic process GO:0009057 281 0.021
regulation of ion transmembrane transporter activity GO:0032412 54 0.020
negative regulation of protein modification process GO:0031400 163 0.020
protein maturation GO:0051604 176 0.020
mitotic cell cycle GO:0000278 195 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
thermosensory behavior GO:0040040 1 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
telencephalon development GO:0021537 186 0.020
positive regulation of nervous system development GO:0051962 221 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
germ cell development GO:0007281 185 0.020
regulation of voltage gated calcium channel activity GO:1901385 4 0.020
action potential GO:0001508 78 0.020
protein targeting GO:0006605 143 0.020
regulation of cell projection organization GO:0031344 206 0.020
aromatic compound catabolic process GO:0019439 286 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.019
nuclear transport GO:0051169 139 0.019
carbohydrate metabolic process GO:0005975 230 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
nucleoside catabolic process GO:0009164 206 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
metal ion homeostasis GO:0055065 189 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
positive regulation of apoptotic cell clearance GO:2000427 3 0.019
heart contraction GO:0060047 93 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
amide transport GO:0042886 138 0.019
regulation of transporter activity GO:0032409 57 0.019
negative regulation of cellular component organization GO:0051129 194 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
angiogenesis GO:0001525 201 0.018
myotube differentiation GO:0014902 105 0.018
regulation of cell cycle GO:0051726 281 0.018
rho protein signal transduction GO:0007266 32 0.018
positive regulation of protein modification process GO:0031401 299 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
long term synaptic potentiation GO:0060291 25 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
purine containing compound metabolic process GO:0072521 311 0.018
regulation of cell cycle process GO:0010564 160 0.018
lipid localization GO:0010876 126 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
synaptic transmission glutamatergic GO:0035249 36 0.018
regulation of hydrolase activity GO:0051336 246 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
axonogenesis GO:0007409 274 0.017
actin cytoskeleton organization GO:0030036 220 0.017
potassium ion transport GO:0006813 52 0.017
response to radiation GO:0009314 165 0.017
mitotic cell cycle process GO:1903047 159 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
positive regulation of secretion GO:0051047 130 0.017
organelle fission GO:0048285 170 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
eye photoreceptor cell development GO:0042462 31 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
positive regulation of protein kinase activity GO:0045860 144 0.016
photoreceptor cell differentiation GO:0046530 52 0.016
neuromuscular process controlling balance GO:0050885 59 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
sensory perception GO:0007600 245 0.016
lateral inhibition GO:0046331 1 0.016
peptide secretion GO:0002790 114 0.016
cell growth GO:0016049 130 0.016
dna metabolic process GO:0006259 303 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
neuromuscular process GO:0050905 99 0.016
gliogenesis GO:0042063 141 0.016
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.016
branching morphogenesis of an epithelial tube GO:0048754 159 0.016
regulation of transferase activity GO:0051338 263 0.016
cellular response to lipid GO:0071396 145 0.015
fat cell differentiation GO:0045444 160 0.015
cellular chemical homeostasis GO:0055082 215 0.015
organelle localization GO:0051640 179 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of proteolysis GO:0030162 164 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
vascular process in circulatory system GO:0003018 62 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
positive regulation of cell death GO:0010942 224 0.015
regulation of engulfment of apoptotic cell GO:1901074 2 0.015
negative regulation of cell development GO:0010721 169 0.015
Mouse
organophosphate biosynthetic process GO:0090407 122 0.015
gastrin induced gastric acid secretion GO:0001698 1 0.015
epithelial cell development GO:0002064 159 0.015
urogenital system development GO:0001655 261 0.015
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
nuclear division GO:0000280 158 0.015
wnt signaling pathway GO:0016055 188 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.014
chondrocyte differentiation GO:0002062 72 0.014
protein import GO:0017038 101 0.014
neural precursor cell proliferation GO:0061351 121 0.014
response to light stimulus GO:0009416 135 0.014
substantia nigra development GO:0021762 2 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
nuclear import GO:0051170 95 0.014
organophosphate catabolic process GO:0046434 232 0.014
metencephalon development GO:0022037 89 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
cellular protein catabolic process GO:0044257 155 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
extracellular structure organization GO:0043062 148 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
defecation GO:0030421 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
digestive system development GO:0055123 200 0.014
protein secretion GO:0009306 111 0.014
striated muscle cell development GO:0055002 125 0.014
regulation of peptide transport GO:0090087 91 0.014
multicellular organism growth GO:0035264 161 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
cell proliferation in hindbrain GO:0021534 10 0.014
microtubule based process GO:0007017 236 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
response to acid chemical GO:0001101 111 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
regulation of blood pressure GO:0008217 93 0.013
somite development GO:0061053 81 0.013
asymmetric stem cell division GO:0098722 3 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
regulation of feeding behavior GO:0060259 3 0.013
rhythmic process GO:0048511 174 0.013
regulation of neuron projection development GO:0010975 169 0.013
negative regulation of neuron differentiation GO:0045665 101 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
purine containing compound catabolic process GO:0072523 213 0.013
kidney development GO:0001822 213 0.013
regulation of cell adhesion GO:0030155 154 0.013
lipid transport GO:0006869 98 0.013
negative regulation of transferase activity GO:0051348 85 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of organelle organization GO:0033043 289 0.013
regulation of homeostatic process GO:0032844 182 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
regulation of mapk cascade GO:0043408 248 0.013
photoreceptor cell development GO:0042461 40 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
protein localization to nucleus GO:0034504 121 0.013
peptide transport GO:0015833 133 0.013
metanephros development GO:0001656 79 0.013
dephosphorylation GO:0016311 129 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
nucleotide catabolic process GO:0009166 217 0.013
cell adhesion GO:0007155 329 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
regulation of muscle tissue development GO:1901861 97 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
developmental maturation GO:0021700 193 0.013
negative regulation of growth GO:0045926 99 0.013
organic anion transport GO:0015711 137 0.013
response to molecule of bacterial origin GO:0002237 143 0.012
wound healing GO:0042060 157 0.012
single organism nuclear import GO:1902593 95 0.012
maintenance of location GO:0051235 89 0.012
regulation of sodium ion transport GO:0002028 29 0.012
heart process GO:0003015 94 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of ph GO:0006885 26 0.012
response to lipopolysaccharide GO:0032496 128 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
regulation of anatomical structure size GO:0090066 178 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
blood circulation GO:0008015 195 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
cellular ion homeostasis GO:0006873 165 0.012
chondrocyte hypertrophy GO:0003415 4 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
cell type specific apoptotic process GO:0097285 268 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
sulfur compound metabolic process GO:0006790 100 0.012
forebrain cell migration GO:0021885 58 0.012
glial cell differentiation GO:0010001 131 0.012
Mouse
ossification GO:0001503 216 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
cell division GO:0051301 120 0.012
stem cell proliferation GO:0072089 117 0.012
development of primary sexual characteristics GO:0045137 143 0.012
cell proliferation in external granule layer GO:0021924 10 0.012
positive regulation of epithelial cell proliferation GO:0050679 68 0.012
regulation of cell migration GO:0030334 219 0.012
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 3 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
regulation of protein maturation GO:1903317 96 0.012
bone morphogenesis GO:0060349 78 0.012
respiratory tube development GO:0030323 167 0.012
protein processing GO:0016485 163 0.011
regulation of secretion by cell GO:1903530 249 0.011
pallium development GO:0021543 120 0.011
regulation of cell motility GO:2000145 236 0.011
somatotropin secreting cell differentiation GO:0060126 4 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
anatomical structure homeostasis GO:0060249 145 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
translation GO:0006412 93 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
positive regulation of cell cycle GO:0045787 92 0.011
multi multicellular organism process GO:0044706 109 0.011
positive regulation of protein transport GO:0051222 93 0.011
interleukin 8 production GO:0032637 4 0.011
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of cellular response to stress GO:0080135 159 0.011
synapse organization GO:0050808 125 0.011
rna processing GO:0006396 105 0.011
positive regulation of phagocytosis engulfment GO:0060100 3 0.011
notch signaling pathway GO:0007219 71 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of response to wounding GO:1903034 189 0.011
hormone metabolic process GO:0042445 86 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
single organism cell adhesion GO:0098602 156 0.011
regulation of serotonin secretion GO:0014062 3 0.011
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
regulation of map kinase activity GO:0043405 120 0.011
cerebellar granule cell precursor proliferation GO:0021930 10 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
asymmetric neuroblast division GO:0055059 1 0.011
regulation of stem cell proliferation GO:0072091 78 0.011
response to growth factor GO:0070848 198 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
regulation of binding GO:0051098 111 0.011
regulation of hormone levels GO:0010817 211 0.010
glutamate receptor signaling pathway GO:0007215 35 0.010
tube formation GO:0035148 140 0.010
nucleoside metabolic process GO:0009116 246 0.010
oocyte construction GO:0007308 2 0.010
compound eye development GO:0048749 1 0.010
skeletal muscle cell differentiation GO:0035914 66 0.010
protein autophosphorylation GO:0046777 61 0.010
lymphocyte differentiation GO:0030098 242 0.010
regulation of tube size GO:0035150 57 0.010
cellular response to gamma radiation GO:0071480 4 0.010
stem cell maintenance GO:0019827 130 0.010
gonad morphogenesis GO:0035262 1 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010
hair cycle GO:0042633 90 0.010
potassium ion transmembrane transport GO:0071805 43 0.010
intracellular mrna localization GO:0008298 4 0.010
mrna metabolic process GO:0016071 84 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
positive regulation of transferase activity GO:0051347 167 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
tissue homeostasis GO:0001894 115 0.010
glycerolipid metabolic process GO:0046486 122 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
regulation of rhodopsin gene expression GO:0007468 3 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
regulation of peptide secretion GO:0002791 77 0.010
oviduct development GO:0060066 3 0.010

Lingo3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
sensory system disease DOID:0050155 0 0.027
eye and adnexa disease DOID:1492 0 0.027
eye disease DOID:5614 0 0.027
musculoskeletal system disease DOID:17 0 0.020
retinal disease DOID:5679 0 0.015
retinal degeneration DOID:8466 0 0.010