Mus musculus

61 known processes

Lingo1

leucine rich repeat and Ig domain containing 1

(Aliases: LINGO-1,LERN1,UNQ201,AV148400,4930471K13Rik,Lrrn6a)

Lingo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane depolarization GO:0051899 64 0.216
membrane organization GO:0061024 245 0.208
amine metabolic process GO:0009308 45 0.153
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.118
regulation of membrane potential GO:0042391 192 0.116
Zebrafish
cellular amine metabolic process GO:0044106 44 0.105
regulation of cellular ketone metabolic process GO:0010565 66 0.096
cation transmembrane transport GO:0098655 266 0.080
synaptic vesicle localization GO:0097479 59 0.075
axonogenesis GO:0007409 274 0.075
synapse organization GO:0050808 125 0.074
exocytosis GO:0006887 121 0.067
small gtpase mediated signal transduction GO:0007264 97 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.063
cellular nitrogen compound catabolic process GO:0044270 280 0.062
positive regulation of cellular amine metabolic process GO:0033240 5 0.059
ribonucleoside metabolic process GO:0009119 245 0.059
peptidyl amino acid modification GO:0018193 336 0.059
cellular ketone metabolic process GO:0042180 84 0.057
myeloid cell differentiation GO:0030099 233 0.056
regulation of feeding behavior GO:0060259 3 0.055
purine containing compound catabolic process GO:0072523 213 0.054
carbohydrate derivative catabolic process GO:1901136 231 0.052
rac protein signal transduction GO:0016601 13 0.051
vesicle localization GO:0051648 86 0.051
purine nucleoside triphosphate catabolic process GO:0009146 203 0.051
establishment of vesicle localization GO:0051650 81 0.050
ribonucleotide catabolic process GO:0009261 208 0.048
dendrite development GO:0016358 115 0.046
transmembrane transport GO:0055085 412 0.046
regulation of ion transport GO:0043269 215 0.045
purine ribonucleotide catabolic process GO:0009154 208 0.042
regulation of synaptic plasticity GO:0048167 87 0.042
purine nucleotide catabolic process GO:0006195 211 0.042
negative regulation of phosphorylation GO:0042326 166 0.041
nucleotide metabolic process GO:0009117 332 0.041
nucleoside triphosphate metabolic process GO:0009141 230 0.041
organelle localization GO:0051640 179 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
protein localization to membrane GO:0072657 108 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.039
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
purine nucleoside metabolic process GO:0042278 241 0.037
heterocycle catabolic process GO:0046700 280 0.037
regulation of lipid metabolic process GO:0019216 118 0.037
sensory perception of touch GO:0050975 2 0.037
negative regulation of protein phosphorylation GO:0001933 126 0.036
nucleoside catabolic process GO:0009164 206 0.036
negative regulation of nervous system development GO:0051961 156 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
ribonucleoside catabolic process GO:0042454 206 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
cell adhesion GO:0007155 329 0.033
establishment of synaptic vesicle localization GO:0097480 57 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
regulation of system process GO:0044057 200 0.031
chemotaxis GO:0006935 247 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
negative regulation of molecular function GO:0044092 258 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
compound eye development GO:0048749 1 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
divalent metal ion transport GO:0070838 172 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
nucleoside metabolic process GO:0009116 246 0.029
endocytosis GO:0006897 168 0.029
cellular chemical homeostasis GO:0055082 215 0.029
endomembrane system organization GO:0010256 147 0.029
positive regulation of neuron differentiation GO:0045666 141 0.028
organelle fission GO:0048285 170 0.028
ras protein signal transduction GO:0007265 77 0.028
cellular lipid metabolic process GO:0044255 323 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
regulation of rho gtpase activity GO:0032319 58 0.027
positive regulation of neuron projection development GO:0010976 79 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
myeloid cell homeostasis GO:0002262 114 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
peptidyl tyrosine modification GO:0018212 145 0.026
male gamete generation GO:0048232 285 0.026
sodium ion transmembrane transport GO:0035725 49 0.026
gtp catabolic process GO:0006184 143 0.026
regulation of glutamate receptor signaling pathway GO:1900449 16 0.026
regulation of transferase activity GO:0051338 263 0.025
locomotory behavior GO:0007626 195 0.025
negative regulation of cell development GO:0010721 169 0.025
nucleotide catabolic process GO:0009166 217 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
regulation of ras protein signal transduction GO:0046578 114 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
regulation of hydrolase activity GO:0051336 246 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
cellular response to lipid GO:0071396 145 0.024
regulation of homeostatic process GO:0032844 182 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
negative regulation of protein metabolic process GO:0051248 282 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
intracellular protein transport GO:0006886 204 0.023
response to organonitrogen compound GO:0010243 246 0.023
response to radiation GO:0009314 165 0.023
nitrogen compound transport GO:0071705 271 0.023
membrane lipid biosynthetic process GO:0046467 32 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
purine containing compound metabolic process GO:0072521 311 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
cellular response to peptide hormone stimulus GO:0071375 92 0.022
regulation of secretion GO:0051046 274 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
apoptotic signaling pathway GO:0097190 306 0.022
regulation of neuron differentiation GO:0045664 281 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
muscle cell differentiation GO:0042692 261 0.021
regulation of multi organism process GO:0043900 111 0.021
multi multicellular organism process GO:0044706 109 0.021
wnt signaling pathway GO:0016055 188 0.021
single organism cell adhesion GO:0098602 156 0.021
circulatory system process GO:0003013 197 0.020
carbohydrate metabolic process GO:0005975 230 0.020
neuron projection guidance GO:0097485 141 0.020
rho protein signal transduction GO:0007266 32 0.020
negative regulation of protein modification process GO:0031400 163 0.020
blood circulation GO:0008015 195 0.020
organophosphate catabolic process GO:0046434 232 0.020
mitochondrion organization GO:0007005 134 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.020
golgi to endosome transport GO:0006895 3 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
neuroblast division in subventricular zone GO:0021849 2 0.019
gtp metabolic process GO:0046039 144 0.019
cell recognition GO:0008037 83 0.019
regulation of mapk cascade GO:0043408 248 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
synaptic vesicle transport GO:0048489 57 0.019
oocyte axis specification GO:0007309 2 0.019
axon guidance GO:0007411 141 0.018
regulation of postsynaptic membrane potential GO:0060078 48 0.018
calcium ion homeostasis GO:0055074 127 0.018
multi organism behavior GO:0051705 62 0.018
cell maturation GO:0048469 127 0.018
heart process GO:0003015 94 0.018
fertilization GO:0009566 127 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
maintenance of location GO:0051235 89 0.017
developmental maturation GO:0021700 193 0.017
synapse assembly GO:0007416 56 0.017
sphingolipid biosynthetic process GO:0030148 26 0.017
maintenance of presynaptic active zone structure GO:0048790 1 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
amide transport GO:0042886 138 0.017
regulation of receptor activity GO:0010469 41 0.017
spermatid development GO:0007286 108 0.017
central nervous system projection neuron axonogenesis GO:0021952 21 0.017
engulfment of apoptotic cell GO:0043652 3 0.016
protein autophosphorylation GO:0046777 61 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
aromatic compound catabolic process GO:0019439 286 0.016
spermatogenesis GO:0007283 284 0.016
regulation of cell cycle process GO:0010564 160 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
actin cytoskeleton organization GO:0030036 220 0.016
muscle tissue development GO:0060537 308 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.015
vesicle organization GO:0016050 60 0.015
regulation of organelle organization GO:0033043 289 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
visual learning GO:0008542 44 0.015
synaptic transmission GO:0007268 329 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
defecation GO:0030421 1 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
regulation of cell adhesion GO:0030155 154 0.015
negative regulation of synapse assembly GO:0051964 3 0.015
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.015
blood vessel morphogenesis GO:0048514 285 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of cellular component size GO:0032535 121 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
response to light stimulus GO:0009416 135 0.014
single fertilization GO:0007338 82 0.014
leukocyte migration GO:0050900 124 0.014
regulation of metal ion transport GO:0010959 106 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
establishment of organelle localization GO:0051656 122 0.014
sperm motility GO:0030317 47 0.014
carbohydrate biosynthetic process GO:0016051 74 0.014
phospholipid metabolic process GO:0006644 87 0.014
lipid biosynthetic process GO:0008610 179 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
dephosphorylation GO:0016311 129 0.013
positive regulation of growth GO:0045927 104 0.013
pole plasm assembly GO:0007315 2 0.013
developmental cell growth GO:0048588 84 0.013
response to nutrient levels GO:0031667 109 0.013
positive regulation of intracellular transport GO:0032388 70 0.013
response to peptide GO:1901652 136 0.013
inflammatory response GO:0006954 244 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
positive regulation of cell death GO:0010942 224 0.013
leukocyte differentiation GO:0002521 342 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
oocyte construction GO:0007308 2 0.013
mitotic cytokinesis GO:0000281 4 0.013
directional locomotion GO:0033058 3 0.013
homeostasis of number of cells GO:0048872 210 0.013
cellular homeostasis GO:0019725 240 0.013
nuclear division GO:0000280 158 0.013
organelle assembly GO:0070925 177 0.013
response to insulin GO:0032868 100 0.013
retina development in camera type eye GO:0060041 119 0.013
cellular ion homeostasis GO:0006873 165 0.013
divalent inorganic cation transport GO:0072511 178 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
ion transmembrane transport GO:0034220 361 0.013
neurotransmitter secretion GO:0007269 62 0.013
regulation of actin filament based process GO:0032970 99 0.013
calcium ion transport GO:0006816 159 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.012
axonal fasciculation GO:0007413 15 0.012
synaptic transmission glutamatergic GO:0035249 36 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of cell projection organization GO:0031344 206 0.012
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
muscle contraction GO:0006936 101 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
dna metabolic process GO:0006259 303 0.012
germ cell development GO:0007281 185 0.012
mapk cascade GO:0000165 281 0.012
regulation of transporter activity GO:0032409 57 0.012
multicellular organism growth GO:0035264 161 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of cell size GO:0008361 72 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
plasma membrane organization GO:0007009 90 0.011
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.011
protein maturation GO:0051604 176 0.011
cation transport GO:0006812 399 0.011
histone modification GO:0016570 159 0.011
anion transport GO:0006820 177 0.011
sphingolipid metabolic process GO:0006665 45 0.011
lipid modification GO:0030258 65 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
cellular response to peptide GO:1901653 92 0.011
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.011
cardiac muscle cell contraction GO:0086003 7 0.011
meiotic nuclear division GO:0007126 115 0.011
synaptic vesicle exocytosis GO:0016079 26 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
mrna metabolic process GO:0016071 84 0.011
cell division GO:0051301 120 0.011
rap protein signal transduction GO:0032486 3 0.011
negative regulation of action potential GO:0045759 1 0.011
positive regulation of necrotic cell death GO:0010940 1 0.011
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
positive regulation of organelle organization GO:0010638 128 0.010
sodium ion transport GO:0006814 73 0.010
metencephalon development GO:0022037 89 0.010
regulation of anatomical structure size GO:0090066 178 0.010
fast calcium ion dependent exocytosis of neurotransmitter GO:0098746 1 0.010
cell growth GO:0016049 130 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
organic anion transport GO:0015711 137 0.010
regulation of transmembrane transport GO:0034762 128 0.010
actin filament based movement GO:0030048 23 0.010
protein targeting to membrane GO:0006612 20 0.010

Lingo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016