|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.832
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.787
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.740
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.674
|
Human Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.662
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.658
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.602
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.554
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.508
|
Human |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.504
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.500
|
|
|
|
rhombomere formation
|
GO:0021594 |
1 |
0.486
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.460
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.430
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.430
|
Human Fly |
|
|
germ cell development
|
GO:0007281 |
185 |
0.425
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.414
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.395
|
Worm Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.379
|
Human |
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.375
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.374
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.372
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.369
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.360
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.358
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.355
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.354
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.354
|
Human Worm |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.351
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.347
|
Mouse Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.339
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.337
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.337
|
Human Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.326
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.324
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.323
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.323
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.322
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.320
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.310
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.310
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.309
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.304
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.303
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.303
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.303
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.299
|
|
|
|
memory
|
GO:0007613 |
58 |
0.295
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.288
|
Human Worm |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.288
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.287
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.284
|
Human Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.282
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.280
|
Mouse Worm |
|
|
muscle system process
|
GO:0003012 |
141 |
0.279
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.278
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.278
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.277
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.274
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.273
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.273
|
Human Fly |
|
|
t cell activation
|
GO:0042110 |
289 |
0.272
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.270
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.265
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.264
|
Fly |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.262
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.260
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.246
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.246
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.239
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.239
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.239
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.238
|
Fly |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.237
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.228
|
|
|
|
positive regulation of macroautophagy
|
GO:0016239 |
3 |
0.227
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.226
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.224
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.224
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.223
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.218
|
|
|
|
rna catabolic process
|
GO:0006401 |
29 |
0.216
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.215
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.215
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.214
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.212
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.211
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.211
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.210
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.207
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.207
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.206
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.203
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.201
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.195
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.195
|
Fly |
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.191
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.190
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.187
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.187
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.185
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.184
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.182
|
Worm |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.181
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.180
|
Fly |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.178
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.175
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.172
|
Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.172
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.172
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.168
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.168
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.166
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.165
|
Fly |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.165
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.165
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.164
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.164
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.163
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.163
|
|
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.162
|
Mouse |
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.158
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.157
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.157
|
Human Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.157
|
|
|
|
phospholipid transfer to membrane
|
GO:0006649 |
2 |
0.155
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.154
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.152
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.151
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.150
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.149
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.149
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.148
|
Fly |
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.147
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.147
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.146
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.145
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.145
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.144
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.144
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.143
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.143
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.142
|
Fly |
|
|
response to starvation
|
GO:0042594 |
65 |
0.142
|
Human Fly |
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.142
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.142
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.142
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.141
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.139
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.139
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.138
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.138
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.138
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.137
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.136
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.135
|
Fly |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.134
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.134
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.134
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.134
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.132
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.132
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.132
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.131
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.131
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.131
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.131
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.129
|
Mouse Fly |
|
|
molting cycle
|
GO:0042303 |
90 |
0.126
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.125
|
Worm |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.125
|
Human |
|
|
response to insulin
|
GO:0032868 |
100 |
0.124
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.124
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.124
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.124
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.124
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.124
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.123
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.121
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.121
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.121
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.121
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.120
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.120
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.118
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.118
|
|
|
|
aortic valve morphogenesis
|
GO:0003180 |
4 |
0.117
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.116
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.116
|
Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.116
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.116
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.115
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.115
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
2 |
0.114
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.114
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.114
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.113
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.112
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.112
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.111
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.111
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.110
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.109
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.108
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.108
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.108
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.107
|
Human Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.107
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.107
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.106
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.106
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.106
|
|
|
|
n terminal protein amino acid modification
|
GO:0031365 |
6 |
0.106
|
|
|
|
cellular response to follicle stimulating hormone stimulus
|
GO:0071372 |
1 |
0.105
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.105
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.105
|
Fly |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.105
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.104
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.102
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.102
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.101
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.101
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.101
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.100
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.100
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.100
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.100
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.100
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.097
|
|
|
|
regulation of transcription involved in cell fate commitment
|
GO:0060850 |
15 |
0.097
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.097
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.097
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
18 |
0.096
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.096
|
|
|
|
growth involved in heart morphogenesis
|
GO:0003241 |
4 |
0.095
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.094
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.094
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061418 |
2 |
0.093
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.093
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.092
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
51 |
0.091
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.091
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.091
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.090
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.090
|
|
|
|
heart trabecula morphogenesis
|
GO:0061384 |
26 |
0.090
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.090
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.089
|
|
|
|
rhombomere morphogenesis
|
GO:0021593 |
2 |
0.089
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.088
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.088
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.087
|
Mouse |
|
|
somite development
|
GO:0061053 |
81 |
0.087
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.087
|
Fly |
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
3 |
0.087
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.087
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.086
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.086
|
Human Fly |
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.085
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
12 |
0.085
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.085
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.085
|
Mouse |
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.084
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.084
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.084
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.084
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.084
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
4 |
0.084
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.083
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.083
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.082
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.082
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.082
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.082
|
|
|
|
atrioventricular node development
|
GO:0003162 |
3 |
0.081
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.081
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
20 |
0.081
|
Human |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.081
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.081
|
|
|
|
mesangial cell development
|
GO:0072143 |
4 |
0.081
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.081
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.081
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.080
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.080
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.080
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.080
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.080
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.080
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.079
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.079
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.079
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.078
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
2 |
0.078
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.078
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.077
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.076
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.076
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.076
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.076
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.076
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.076
|
|
|
|
positive regulation of keratinocyte differentiation
|
GO:0045618 |
3 |
0.076
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.075
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.075
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.075
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.075
|
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
4 |
0.075
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.074
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.074
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.074
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.074
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
4 |
0.074
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.073
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.073
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
3 |
0.073
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.073
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.072
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.072
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.072
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.072
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.071
|
Fly |
|
|
determination of heart left right asymmetry
|
GO:0061371 |
48 |
0.071
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.071
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.070
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.070
|
Human Worm |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.070
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.070
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.068
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.068
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.068
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.067
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.067
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.066
|
|
|
|
positive regulation of mesoderm development
|
GO:2000382 |
2 |
0.066
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.066
|
|
|
|
cardiac cell fate specification
|
GO:0060912 |
2 |
0.066
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.066
|
Human |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.066
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.066
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.066
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.065
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.065
|
Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.065
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.064
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.064
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.064
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.064
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.063
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.063
|
Fly |
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.063
|
|
|
|
cardiac right atrium morphogenesis
|
GO:0003213 |
3 |
0.063
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.063
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.063
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.063
|
|
|
|
regulation of endothelial cell chemotaxis
|
GO:2001026 |
1 |
0.063
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
31 |
0.063
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.062
|
Worm |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.062
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.062
|
|
|
|
cell migration involved in endocardial cushion formation
|
GO:0003273 |
3 |
0.061
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.061
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.061
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.061
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.061
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.061
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.061
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.059
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.059
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.059
|
Fly |
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.059
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.058
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.058
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.058
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.058
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.058
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.058
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.058
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.058
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.058
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.057
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.057
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
8 |
0.057
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.057
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.057
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.057
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.057
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.057
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.057
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.056
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.056
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.056
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.056
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.056
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.055
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.055
|
|
|
|
cellular carbohydrate catabolic process
|
GO:0044275 |
15 |
0.055
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.055
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.055
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.055
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.055
|
Fly |
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.054
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.054
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.054
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.054
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.054
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.054
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.054
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.054
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.054
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.054
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.053
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.053
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.053
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.053
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.053
|
|
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.053
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.053
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.052
|
|
|
|
zygotic determination of anterior posterior axis embryo
|
GO:0007354 |
3 |
0.052
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.052
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.052
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.052
|
Fly |
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.052
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.052
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.051
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.051
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.051
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.051
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.050
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.050
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.050
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.050
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.050
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.050
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.050
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.050
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.050
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.050
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.050
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.050
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.050
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.050
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.049
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.049
|
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
4 |
0.049
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.049
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.049
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.049
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.049
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.049
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.049
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.048
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.048
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.048
|
|
|
|
clara cell differentiation
|
GO:0060486 |
4 |
0.048
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.048
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.048
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.048
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.048
|
Worm Fly |
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.048
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.048
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.048
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.047
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.047
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.047
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.047
|
Fly |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.047
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.047
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.047
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.047
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.046
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.046
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.046
|
Mouse |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.046
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.046
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.046
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.046
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.046
|
|
|
|
response to follicle stimulating hormone
|
GO:0032354 |
1 |
0.046
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.046
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.045
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.045
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.045
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.045
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.045
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.045
|
|
|
|
primitive hemopoiesis
|
GO:0060215 |
7 |
0.045
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.045
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.045
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.045
|
Fly |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.045
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.044
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.044
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.044
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.044
|
|
