Mus musculus

20 known processes

Slc24a4

solute carrier family 24 (sodium/potassium/calcium exchanger), member 4

(Aliases: AW492432,NCKX4,A930002M03Rik)

Slc24a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic cation transmembrane transport GO:0098662 207 0.210
Mouse Rat
cation transmembrane transport GO:0098655 266 0.168
Mouse Rat
ion transmembrane transport GO:0034220 361 0.157
Mouse Rat
regulation of membrane potential GO:0042391 192 0.132
transmembrane transport GO:0055085 412 0.102
Mouse Rat
inorganic ion transmembrane transport GO:0098660 234 0.101
Mouse Rat
regulation of system process GO:0044057 200 0.072
forebrain development GO:0030900 302 0.068
nucleotide metabolic process GO:0009117 332 0.066
ribose phosphate metabolic process GO:0019693 291 0.063
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
cation transport GO:0006812 399 0.054
Mouse Rat
positive regulation of cell development GO:0010720 237 0.051
transmission of nerve impulse GO:0019226 76 0.047
purine nucleotide metabolic process GO:0006163 302 0.045
ribonucleotide metabolic process GO:0009259 291 0.045
organonitrogen compound catabolic process GO:1901565 264 0.043
ribonucleoside metabolic process GO:0009119 245 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.042
axonogenesis GO:0007409 274 0.042
regulation of hydrolase activity GO:0051336 246 0.042
positive regulation of nervous system development GO:0051962 221 0.042
organic anion transport GO:0015711 137 0.042
aromatic compound catabolic process GO:0019439 286 0.041
purine containing compound metabolic process GO:0072521 311 0.040
cellular amine metabolic process GO:0044106 44 0.040
purine ribonucleotide metabolic process GO:0009150 290 0.040
regulation of neuron differentiation GO:0045664 281 0.039
mapk cascade GO:0000165 281 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
developmental maturation GO:0021700 193 0.038
germ cell development GO:0007281 185 0.038
organic cyclic compound catabolic process GO:1901361 295 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
positive regulation of mapk cascade GO:0043410 170 0.037
regulation of cell projection organization GO:0031344 206 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
regulation of cellular catabolic process GO:0031329 242 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.036
regulation of transmembrane transport GO:0034762 128 0.036
nucleoside metabolic process GO:0009116 246 0.036
negative regulation of cell proliferation GO:0008285 296 0.036
potassium ion transport GO:0006813 52 0.036
Mouse Rat
regulation of nucleotide metabolic process GO:0006140 169 0.035
ras protein signal transduction GO:0007265 77 0.034
regulation of cell cycle GO:0051726 281 0.034
regulation of ion transmembrane transport GO:0034765 119 0.034
purine nucleoside metabolic process GO:0042278 241 0.033
negative regulation of cell development GO:0010721 169 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
apoptotic signaling pathway GO:0097190 306 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
synaptic transmission GO:0007268 329 0.032
male gamete generation GO:0048232 285 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
potassium ion transmembrane transport GO:0071805 43 0.031
Mouse Rat
negative regulation of protein metabolic process GO:0051248 282 0.031
nitrogen compound transport GO:0071705 271 0.031
skeletal system development GO:0001501 356 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.030
regulation of long term synaptic depression GO:1900452 3 0.030
spermatogenesis GO:0007283 284 0.029
camera type eye development GO:0043010 266 0.029
cognition GO:0050890 149 0.029
positive regulation of protein modification process GO:0031401 299 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
ribonucleoside catabolic process GO:0042454 206 0.029
nucleoside catabolic process GO:0009164 206 0.029
synapse organization GO:0050808 125 0.028
multicellular organismal signaling GO:0035637 91 0.028
negative regulation of synapse assembly GO:0051964 3 0.028
regulation of cellular response to stress GO:0080135 159 0.028
amino acid transmembrane transport GO:0003333 37 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
negative regulation of cellular component organization GO:0051129 194 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
cation homeostasis GO:0055080 212 0.027
Rat
habituation GO:0046959 3 0.027
positive regulation of neuron differentiation GO:0045666 141 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
sensory organ morphogenesis GO:0090596 242 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
membrane organization GO:0061024 245 0.027
regulation of secretion by cell GO:1903530 249 0.026
heterocycle catabolic process GO:0046700 280 0.026
divalent inorganic cation transport GO:0072511 178 0.026
Mouse Rat
purine ribonucleoside metabolic process GO:0046128 241 0.026
retina development in camera type eye GO:0060041 119 0.025
regulation of mapk cascade GO:0043408 248 0.025
lateral inhibition GO:0046331 1 0.025
regulation of ion transport GO:0043269 215 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
neuron death GO:0070997 154 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
cellular response to organic cyclic compound GO:0071407 87 0.024
positive regulation of protein kinase activity GO:0045860 144 0.024
response to organonitrogen compound GO:0010243 246 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
regulation of neuron projection development GO:0010975 169 0.024
central nervous system neuron differentiation GO:0021953 162 0.024
protein maturation GO:0051604 176 0.024
metal ion homeostasis GO:0055065 189 0.024
Rat
nucleotide catabolic process GO:0009166 217 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
amine metabolic process GO:0009308 45 0.024
macromolecule catabolic process GO:0009057 281 0.024
regulation of transferase activity GO:0051338 263 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
negative regulation of nervous system development GO:0051961 156 0.024
sensory perception GO:0007600 245 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
cellular ketone metabolic process GO:0042180 84 0.023
response to organic cyclic compound GO:0014070 198 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
cell type specific apoptotic process GO:0097285 268 0.023
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
cellular potassium ion transport GO:0071804 43 0.022
Mouse Rat
locomotory behavior GO:0007626 195 0.022
learning GO:0007612 98 0.022
heart contraction GO:0060047 93 0.021
protein catabolic process GO:0030163 221 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
organelle localization GO:0051640 179 0.021
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
calcium ion transport GO:0006816 159 0.021
Mouse Rat
negative regulation of growth GO:0045926 99 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
immune effector process GO:0002252 321 0.021
regulation of organelle organization GO:0033043 289 0.021
chemotaxis GO:0006935 247 0.020
regulation of proteolysis GO:0030162 164 0.020
negative regulation of molecular function GO:0044092 258 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
endocytosis GO:0006897 168 0.020
actin cytoskeleton organization GO:0030036 220 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
gtp catabolic process GO:0006184 143 0.020
cellular homeostasis GO:0019725 240 0.019
Rat
neuron apoptotic process GO:0051402 142 0.019
protein processing GO:0016485 163 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
negative regulation of neuron differentiation GO:0045665 101 0.019
calcium ion transmembrane transport GO:0070588 85 0.019
Mouse Rat
peptidyl amino acid modification GO:0018193 336 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.019
regulation of body fluid levels GO:0050878 162 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
muscle contraction GO:0006936 101 0.019
muscle cell differentiation GO:0042692 261 0.019
interleukin 8 production GO:0032637 4 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
purine containing compound catabolic process GO:0072523 213 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
leukocyte differentiation GO:0002521 342 0.018
sodium ion transmembrane transport GO:0035725 49 0.018
Mouse Rat
cytoplasmic transport GO:0016482 234 0.018
intracellular protein transport GO:0006886 204 0.018
neuron neuron synaptic transmission GO:0007270 69 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
t cell activation GO:0042110 289 0.018
dorsal ventral axon guidance GO:0033563 3 0.018
regionalization GO:0003002 337 0.018
regulation of secretion GO:0051046 274 0.018
memory GO:0007613 58 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
blood circulation GO:0008015 195 0.018
fat cell differentiation GO:0045444 160 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
regulation of kinase activity GO:0043549 249 0.017
negative regulation of protein modification process GO:0031400 163 0.017
spermatid development GO:0007286 108 0.017
purine nucleotide biosynthetic process GO:0006164 65 0.017
learning or memory GO:0007611 148 0.017
circulatory system process GO:0003013 197 0.017
action potential GO:0001508 78 0.017
cell recognition GO:0008037 83 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
heart process GO:0003015 94 0.017
microtubule based process GO:0007017 236 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
anion transport GO:0006820 177 0.016
purine containing compound biosynthetic process GO:0072522 70 0.016
rho protein signal transduction GO:0007266 32 0.016
telencephalon development GO:0021537 186 0.016
response to inorganic substance GO:0010035 96 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
organophosphate catabolic process GO:0046434 232 0.016
cyclic nucleotide metabolic process GO:0009187 59 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
anion transmembrane transport GO:0098656 71 0.016
defecation GO:0030421 1 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
positive regulation of transferase activity GO:0051347 167 0.016
dephosphorylation GO:0016311 129 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
protein localization to organelle GO:0033365 185 0.016
regulation of cell motility GO:2000145 236 0.016
cellular ion homeostasis GO:0006873 165 0.016
Rat
regulation of blood circulation GO:1903522 93 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
regulation of neuron death GO:1901214 134 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
purine ribonucleotide biosynthetic process GO:0009152 59 0.015
positive regulation of cell death GO:0010942 224 0.015
urogenital system development GO:0001655 261 0.015
neuron migration GO:0001764 122 0.015
peptide transport GO:0015833 133 0.015
regulation of t cell activation GO:0050863 170 0.015
connective tissue development GO:0061448 179 0.015
t cell differentiation in thymus GO:0033077 77 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of cell activation GO:0050865 289 0.015
regulation of cellular component size GO:0032535 121 0.015
carboxylic acid transport GO:0046942 100 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
amino acid transport GO:0006865 61 0.014
glutamate receptor signaling pathway GO:0007215 35 0.014
sodium ion transport GO:0006814 73 0.014
Mouse Rat
lymphocyte differentiation GO:0030098 242 0.014
regulation of protein kinase activity GO:0045859 232 0.014
response to growth factor GO:0070848 198 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of protein catabolic process GO:0042176 108 0.014
single organism cell adhesion GO:0098602 156 0.014
exocytosis GO:0006887 121 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
cell growth GO:0016049 130 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
eye photoreceptor cell development GO:0042462 31 0.014
maintenance of location GO:0051235 89 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
t cell differentiation GO:0030217 174 0.013
organelle assembly GO:0070925 177 0.013
cellular protein catabolic process GO:0044257 155 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
neuromuscular process GO:0050905 99 0.013
regulation of anatomical structure size GO:0090066 178 0.013
protein ubiquitination GO:0016567 171 0.013
cyclic purine nucleotide metabolic process GO:0052652 43 0.013
positive regulation of kinase activity GO:0033674 155 0.013
body fluid secretion GO:0007589 53 0.013
neuron projection guidance GO:0097485 141 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
compound eye development GO:0048749 1 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
positive regulation of secretion GO:0051047 130 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
skeletal muscle organ development GO:0060538 163 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
cell adhesion GO:0007155 329 0.013
organic acid transport GO:0015849 101 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of cell growth GO:0001558 91 0.013
membrane depolarization GO:0051899 64 0.013
organelle fission GO:0048285 170 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
positive regulation of ras gtpase activity GO:0032320 65 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
nuclear division GO:0000280 158 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
neural retina development GO:0003407 41 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
regulation of transporter activity GO:0032409 57 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
gland development GO:0048732 330 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
regulation of muscle system process GO:0090257 80 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
mitotic cell cycle GO:0000278 195 0.012
positive regulation of phagocytosis engulfment GO:0060100 3 0.012
renal system development GO:0072001 225 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of cell migration GO:0030334 219 0.012
positive regulation of cell cycle GO:0045787 92 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
regulation of engulfment of apoptotic cell GO:1901074 2 0.012
regulation of binding GO:0051098 111 0.012
response to transforming growth factor beta GO:0071559 88 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
regulation of cytokine production GO:0001817 266 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
positive regulation of growth GO:0045927 104 0.012
cellular response to lipid GO:0071396 145 0.012
ossification GO:0001503 216 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
kidney development GO:0001822 213 0.012
regulation of protein processing GO:0070613 96 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of cell cycle process GO:0010564 160 0.012
calcium ion homeostasis GO:0055074 127 0.012
Rat
protein targeting GO:0006605 143 0.012
camp metabolic process GO:0046058 40 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
dendrite development GO:0016358 115 0.012
interleukin 8 secretion GO:0072606 3 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
mesodermal cell migration GO:0008078 4 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
positive regulation of neuron projection development GO:0010976 79 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
epithelial cell proliferation GO:0050673 174 0.011
cellular chemical homeostasis GO:0055082 215 0.011
Rat
positive regulation of cellular component biogenesis GO:0044089 94 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of interleukin 8 secretion GO:2000482 2 0.011
cardiocyte differentiation GO:0035051 87 0.011
synaptic transmission glutamatergic GO:0035249 36 0.011
regulation of ossification GO:0030278 112 0.011
divalent metal ion transport GO:0070838 172 0.011
Mouse Rat
dna metabolic process GO:0006259 303 0.011
asymmetric stem cell division GO:0098722 3 0.011
striated muscle tissue development GO:0014706 293 0.011
rap protein signal transduction GO:0032486 3 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
positive regulation of interleukin 8 secretion GO:2000484 1 0.011
cell division GO:0051301 120 0.011
macromolecule methylation GO:0043414 120 0.011
regulation of protein maturation GO:1903317 96 0.011
organic hydroxy compound transport GO:0015850 93 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
spermatid differentiation GO:0048515 115 0.011
protein secretion GO:0009306 111 0.011
regulation of map kinase activity GO:0043405 120 0.011
negative regulation of cell projection organization GO:0031345 56 0.011
cell fate commitment GO:0045165 210 0.011
regulation of feeding behavior GO:0060259 3 0.011
blood coagulation GO:0007596 76 0.011
regulation of cell adhesion GO:0030155 154 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
innate immune response GO:0045087 157 0.011
l amino acid transport GO:0015807 32 0.011
regulation of heart contraction GO:0008016 77 0.011
carbohydrate transport GO:0008643 62 0.010
myeloid cell differentiation GO:0030099 233 0.010
homeostasis of number of cells GO:0048872 210 0.010
angiogenesis GO:0001525 201 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
regulation of nucleotide biosynthetic process GO:0030808 34 0.010
wound healing GO:0042060 157 0.010
neuronal action potential GO:0019228 54 0.010
multicellular organismal response to stress GO:0033555 62 0.010
mitotic cell cycle process GO:1903047 159 0.010
gonad development GO:0008406 141 0.010
regulation of postsynaptic membrane potential GO:0060078 48 0.010
epithelial cell development GO:0002064 159 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
Rat
regulation of voltage gated calcium channel activity GO:1901385 4 0.010
negative regulation of cell cycle GO:0045786 123 0.010
stress activated mapk cascade GO:0051403 80 0.010
tube formation GO:0035148 140 0.010
amide transport GO:0042886 138 0.010
peptide secretion GO:0002790 114 0.010
protein localization to membrane GO:0072657 108 0.010
muscle tissue development GO:0060537 308 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
methylation GO:0032259 134 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
wnt signaling pathway GO:0016055 188 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
platelet activation GO:0030168 40 0.010
regulation of hormone levels GO:0010817 211 0.010
developmental cell growth GO:0048588 84 0.010

Slc24a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.016
disease of anatomical entity DOID:7 0 0.016
central nervous system disease DOID:331 0 0.014
eye and adnexa disease DOID:1492 0 0.010
retinal disease DOID:5679 0 0.010
sensory system disease DOID:0050155 0 0.010
eye disease DOID:5614 0 0.010
retinal degeneration DOID:8466 0 0.010
musculoskeletal system disease DOID:17 0 0.010