Mus musculus

43 known processes

Unc5a

unc-5 homolog A (C. elegans)

(Aliases: Unc5h1,mKIAA1976)

Unc5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.118
cellular amino acid metabolic process GO:0006520 103 0.113
purine containing compound metabolic process GO:0072521 311 0.091
regulation of cellular amine metabolic process GO:0033238 20 0.084
purine nucleotide metabolic process GO:0006163 302 0.075
regulation of cellular ketone metabolic process GO:0010565 66 0.074
gtp catabolic process GO:0006184 143 0.072
nucleobase containing small molecule metabolic process GO:0055086 352 0.070
transmembrane transport GO:0055085 412 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.064
cellular amine metabolic process GO:0044106 44 0.063
cation transport GO:0006812 399 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
ras protein signal transduction GO:0007265 77 0.061
organic cyclic compound catabolic process GO:1901361 295 0.057
cellular nitrogen compound catabolic process GO:0044270 280 0.055
ion transmembrane transport GO:0034220 361 0.055
aromatic compound catabolic process GO:0019439 286 0.054
cation transmembrane transport GO:0098655 266 0.054
nucleoside triphosphate metabolic process GO:0009141 230 0.052
synaptic transmission GO:0007268 329 0.052
cellular ketone metabolic process GO:0042180 84 0.052
amine metabolic process GO:0009308 45 0.051
carbohydrate derivative biosynthetic process GO:1901137 183 0.050
positive regulation of creb transcription factor activity GO:0032793 4 0.050
ribonucleotide metabolic process GO:0009259 291 0.049
nucleotide metabolic process GO:0009117 332 0.048
small gtpase mediated signal transduction GO:0007264 97 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.045
regulation of ion transport GO:0043269 215 0.044
purine ribonucleotide catabolic process GO:0009154 208 0.042
regulation of purine nucleotide metabolic process GO:1900542 169 0.042
nucleoside metabolic process GO:0009116 246 0.040
heterocycle catabolic process GO:0046700 280 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.040
positive regulation of hydrolase activity GO:0051345 148 0.040
inorganic ion transmembrane transport GO:0098660 234 0.040
regulation of hydrolase activity GO:0051336 246 0.039
purine ribonucleoside catabolic process GO:0046130 205 0.039
organophosphate catabolic process GO:0046434 232 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
organelle localization GO:0051640 179 0.038
dna metabolic process GO:0006259 303 0.038
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
membrane organization GO:0061024 245 0.037
purine nucleoside metabolic process GO:0042278 241 0.037
peptidyl amino acid modification GO:0018193 336 0.036
peptidyl tyrosine modification GO:0018212 145 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
nucleoside triphosphate catabolic process GO:0009143 205 0.035
inorganic cation transmembrane transport GO:0098662 207 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
regulation of glutamate receptor signaling pathway GO:1900449 16 0.034
divalent inorganic cation transport GO:0072511 178 0.034
carbohydrate derivative catabolic process GO:1901136 231 0.033
regulation of membrane potential GO:0042391 192 0.033
learning or memory GO:0007611 148 0.033
macromolecule catabolic process GO:0009057 281 0.032
Worm
carbohydrate metabolic process GO:0005975 230 0.031
positive regulation of nucleotide metabolic process GO:0045981 114 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
ribonucleotide catabolic process GO:0009261 208 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.031
regulation of lymphocyte activation GO:0051249 240 0.031
organonitrogen compound catabolic process GO:1901565 264 0.031
purine containing compound catabolic process GO:0072523 213 0.030
cellular homeostasis GO:0019725 240 0.030
cell type specific apoptotic process GO:0097285 268 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
response to organonitrogen compound GO:0010243 246 0.029
apoptotic signaling pathway GO:0097190 306 0.029
calcium ion transport GO:0006816 159 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
nucleoside catabolic process GO:0009164 206 0.028
divalent metal ion transport GO:0070838 172 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.028
urogenital system development GO:0001655 261 0.028
regulation of vesicle mediated transport GO:0060627 139 0.028
negative regulation of immune system process GO:0002683 209 0.028
negative regulation of cellular amine metabolic process GO:0033239 1 0.028
regulation of ion transmembrane transporter activity GO:0032412 54 0.028
positive regulation of gtp catabolic process GO:0033126 85 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
regulation of cell motility GO:2000145 236 0.027
Mouse
cytokine production GO:0001816 319 0.027
nucleotide catabolic process GO:0009166 217 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.027
peptidyl tyrosine phosphorylation GO:0018108 143 0.027
protein localization to membrane GO:0072657 108 0.027
chemotaxis GO:0006935 247 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.026
regulation of transmembrane transport GO:0034762 128 0.026
regulation of secretion GO:0051046 274 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
gtp metabolic process GO:0046039 144 0.026
regulation of transporter activity GO:0032409 57 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
renal system development GO:0072001 225 0.026
regulation of gtp catabolic process GO:0033124 113 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
mapk cascade GO:0000165 281 0.026
fat cell differentiation GO:0045444 160 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
rho protein signal transduction GO:0007266 32 0.025
leukocyte differentiation GO:0002521 342 0.025
regulation of nucleotide metabolic process GO:0006140 169 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
regulation of cell migration GO:0030334 219 0.024
Mouse
negative regulation of molecular function GO:0044092 258 0.024
regulation of ion transmembrane transport GO:0034765 119 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
sensory organ morphogenesis GO:0090596 242 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
immune effector process GO:0002252 321 0.023
regulation of cytokine production GO:0001817 266 0.023
nucleotide biosynthetic process GO:0009165 78 0.023
spermatogenesis GO:0007283 284 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
monosaccharide metabolic process GO:0005996 106 0.022
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
cognition GO:0050890 149 0.022
cellular chemical homeostasis GO:0055082 215 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
glutamate receptor signaling pathway GO:0007215 35 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
regulation of proteolysis GO:0030162 164 0.021
regulation of kinase activity GO:0043549 249 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
glycoprotein metabolic process GO:0009100 116 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
covalent chromatin modification GO:0016569 163 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of cellular component size GO:0032535 121 0.021
Worm
positive regulation of growth GO:0045927 104 0.021
Worm
synapse organization GO:0050808 125 0.020
second messenger mediated signaling GO:0019932 73 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
calcium ion transmembrane transport GO:0070588 85 0.020
regulation of transferase activity GO:0051338 263 0.020
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.020
regulation of t cell activation GO:0050863 170 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
response to radiation GO:0009314 165 0.020
regulation of ras protein signal transduction GO:0046578 114 0.019
regulation of synaptic plasticity GO:0048167 87 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.019
cell adhesion GO:0007155 329 0.019
regulation of cell activation GO:0050865 289 0.019
regulation of secretion by cell GO:1903530 249 0.019
regulation of cell size GO:0008361 72 0.019
Worm
actin cytoskeleton organization GO:0030036 220 0.019
negative regulation of growth GO:0045926 99 0.018
muscle tissue development GO:0060537 308 0.018
protein ubiquitination GO:0016567 171 0.018
hexose metabolic process GO:0019318 98 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
positive regulation of cell death GO:0010942 224 0.018
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.018
cellular response to lipid GO:0071396 145 0.018
regulation of cell adhesion GO:0030155 154 0.018
neurotransmitter transport GO:0006836 76 0.018
regulation of cell cycle GO:0051726 281 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
regulation of protein kinase activity GO:0045859 232 0.018
regulation of response to wounding GO:1903034 189 0.018
regulation of organelle organization GO:0033043 289 0.018
regulation of cell cycle process GO:0010564 160 0.018
lateral inhibition GO:0046331 1 0.018
male gamete generation GO:0048232 285 0.017
stem cell differentiation GO:0048863 268 0.017
histone modification GO:0016570 159 0.017
positive regulation of protein modification process GO:0031401 299 0.017
cation homeostasis GO:0055080 212 0.017
t cell activation GO:0042110 289 0.017
spermatid development GO:0007286 108 0.017
dephosphorylation GO:0016311 129 0.017
kidney development GO:0001822 213 0.017
endomembrane system organization GO:0010256 147 0.017
sensory perception GO:0007600 245 0.017
regulation of neuron death GO:1901214 134 0.017
protein palmitoylation GO:0018345 14 0.017
rhythmic process GO:0048511 174 0.016
ear development GO:0043583 200 0.016
glucose metabolic process GO:0006006 92 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
cellular protein catabolic process GO:0044257 155 0.016
regulation of hormone levels GO:0010817 211 0.016
response to peptide GO:1901652 136 0.016
compound eye development GO:0048749 1 0.016
oxidation reduction process GO:0055114 342 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
negative regulation of protein modification process GO:0031400 163 0.016
myeloid cell differentiation GO:0030099 233 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
mitotic cell cycle process GO:1903047 159 0.016
activation of immune response GO:0002253 138 0.016
mitotic cell cycle GO:0000278 195 0.016
wnt signaling pathway GO:0016055 188 0.016
cell fate commitment GO:0045165 210 0.016
glucose homeostasis GO:0042593 128 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
organelle fission GO:0048285 170 0.016
multicellular organismal signaling GO:0035637 91 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
sulfur compound metabolic process GO:0006790 100 0.015
extracellular structure organization GO:0043062 148 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
skeletal system development GO:0001501 356 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
neuron apoptotic process GO:0051402 142 0.015
cellular response to peptide GO:1901653 92 0.015
response to acid chemical GO:0001101 111 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
memory GO:0007613 58 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
regulation of cell projection organization GO:0031344 206 0.015
Worm
metal ion homeostasis GO:0055065 189 0.015
transmission of nerve impulse GO:0019226 76 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
protein catabolic process GO:0030163 221 0.015
Worm
engulfment of apoptotic cell GO:0043652 3 0.015
negative regulation of camp mediated signaling GO:0043951 3 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
Worm
establishment of synaptic vesicle localization GO:0097480 57 0.014
regulation of body fluid levels GO:0050878 162 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
Mouse
alcohol metabolic process GO:0006066 116 0.014
regulation of engulfment of apoptotic cell GO:1901074 2 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
nitrogen compound transport GO:0071705 271 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
blood circulation GO:0008015 195 0.014
ear morphogenesis GO:0042471 118 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
regionalization GO:0003002 337 0.014
Fly
regulation of mitotic cell cycle GO:0007346 126 0.014
regulation of endocytosis GO:0030100 69 0.014
single organism cell adhesion GO:0098602 156 0.014
gland development GO:0048732 330 0.014
Fly
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
lipid biosynthetic process GO:0008610 179 0.014
positive regulation of ras gtpase activity GO:0032320 65 0.014
chromatin organization GO:0006325 206 0.014
epithelial cell development GO:0002064 159 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
microtubule based process GO:0007017 236 0.014
regulation of neuron projection development GO:0010975 169 0.014
Worm
ribonucleotide biosynthetic process GO:0009260 59 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
regulation of homeostatic process GO:0032844 182 0.014
protein kinase b signaling GO:0043491 74 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
epithelial tube formation GO:0072175 130 0.013
protein autophosphorylation GO:0046777 61 0.013
regulation of long term synaptic depression GO:1900452 3 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
purine containing compound biosynthetic process GO:0072522 70 0.013
striated muscle tissue development GO:0014706 293 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
tissue homeostasis GO:0001894 115 0.013
positive regulation of cell development GO:0010720 237 0.013
Worm
respiratory system development GO:0060541 190 0.013
exocytosis GO:0006887 121 0.013
negative regulation of cell cycle GO:0045786 123 0.013
wound healing GO:0042060 157 0.013
learning GO:0007612 98 0.013
circadian rhythm GO:0007623 114 0.013
nuclear division GO:0000280 158 0.013
sterol metabolic process GO:0016125 58 0.013
intracellular protein transport GO:0006886 204 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
actin filament polymerization GO:0030041 44 0.013
fertilization GO:0009566 127 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
multicellular organism growth GO:0035264 161 0.013
ribose phosphate biosynthetic process GO:0046390 59 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
peptide transport GO:0015833 133 0.013
muscle cell differentiation GO:0042692 261 0.013
negative regulation of cell activation GO:0050866 111 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
vesicle localization GO:0051648 86 0.013
synaptic vesicle localization GO:0097479 59 0.013
leukocyte mediated immunity GO:0002443 174 0.012
leukocyte proliferation GO:0070661 172 0.012
forebrain development GO:0030900 302 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
positive regulation of kinase activity GO:0033674 155 0.012
positive regulation of cell activation GO:0050867 158 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
response to growth factor GO:0070848 198 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
innate immune response GO:0045087 157 0.012
protein acylation GO:0043543 64 0.012
cyclic nucleotide biosynthetic process GO:0009190 44 0.012
peptide secretion GO:0002790 114 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
histone acetylation GO:0016573 41 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
positive regulation of phagocytosis engulfment GO:0060100 3 0.012
immune response activating signal transduction GO:0002757 116 0.012
response to peptide hormone GO:0043434 127 0.012
establishment of vesicle localization GO:0051650 81 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
response to light stimulus GO:0009416 135 0.012
positive regulation of endocytosis GO:0045807 42 0.012
response to extracellular stimulus GO:0009991 127 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
positive regulation of apoptotic cell clearance GO:2000427 3 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
response to organic cyclic compound GO:0014070 198 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
positive regulation of proteolysis GO:0045862 85 0.011
calcium ion homeostasis GO:0055074 127 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
cytokine biosynthetic process GO:0042089 68 0.011
tissue migration GO:0090130 68 0.011
Worm
regulation of protein localization GO:0032880 231 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
cell growth GO:0016049 130 0.011
Worm
tissue remodeling GO:0048771 102 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
lateral line system development GO:0048925 1 0.011
axonogenesis GO:0007409 274 0.011
maintenance of location GO:0051235 89 0.011
protein targeting GO:0006605 143 0.011
chromatin modification GO:0016568 187 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
carbohydrate homeostasis GO:0033500 128 0.011
connective tissue development GO:0061448 179 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
methylation GO:0032259 134 0.011
nephron epithelium development GO:0072009 92 0.011
lymphocyte differentiation GO:0030098 242 0.011
cardiac muscle tissue development GO:0048738 130 0.011
response to lipopolysaccharide GO:0032496 128 0.011
inter male aggressive behavior GO:0002121 3 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
organic anion transport GO:0015711 137 0.011
negative regulation of cell development GO:0010721 169 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
anatomical structure homeostasis GO:0060249 145 0.011
positive regulation of nervous system development GO:0051962 221 0.011
Worm
membrane depolarization GO:0051899 64 0.011
hormone secretion GO:0046879 128 0.011
cellular response to cytokine stimulus GO:0071345 189 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
rac protein signal transduction GO:0016601 13 0.010
regulation of receptor activity GO:0010469 41 0.010
tube formation GO:0035148 140 0.010
regulation of anatomical structure size GO:0090066 178 0.010
Worm
cellular lipid metabolic process GO:0044255 323 0.010
mrna metabolic process GO:0016071 84 0.010
regulation of defense response GO:0031347 233 0.010
renal tubule development GO:0061326 87 0.010
lymphocyte proliferation GO:0046651 164 0.010
defense response to other organism GO:0098542 197 0.010
synaptic vesicle transport GO:0048489 57 0.010
endocytosis GO:0006897 168 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
cellular response to acid chemical GO:0071229 68 0.010
response to insulin GO:0032868 100 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
meiotic nuclear division GO:0007126 115 0.010
midgut development GO:0007494 4 0.010
sensory system development GO:0048880 3 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
macromolecule methylation GO:0043414 120 0.010
germ cell development GO:0007281 185 0.010
regulation of cellular response to stress GO:0080135 159 0.010
regulation of feeding behavior GO:0060259 3 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
purine ribonucleotide biosynthetic process GO:0009152 59 0.010
regulation of chemotaxis GO:0050920 53 0.010

Unc5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.011