Mus musculus

0 known processes

Tgm3

transglutaminase 3, E polypeptide

(Aliases: MGC150256,MGC150257,AI893889)

Tgm3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intermediate filament based process GO:0045103 27 0.685
establishment of skin barrier GO:0061436 14 0.629
keratinocyte differentiation GO:0030216 48 0.558
Human
intermediate filament cytoskeleton organization GO:0045104 26 0.467
cellular amino acid metabolic process GO:0006520 103 0.423
cellular ketone metabolic process GO:0042180 84 0.413
cellular amine metabolic process GO:0044106 44 0.391
hair follicle morphogenesis GO:0031069 29 0.387
regulation of cellular amino acid metabolic process GO:0006521 5 0.255
regulation of water loss via skin GO:0033561 16 0.223
protein maturation GO:0051604 176 0.212
multicellular organismal water homeostasis GO:0050891 23 0.203
water homeostasis GO:0030104 27 0.202
hair cycle GO:0042633 90 0.196
epithelial cell development GO:0002064 159 0.179
apoptotic signaling pathway GO:0097190 306 0.172
regulation of body fluid levels GO:0050878 162 0.160
skin development GO:0043588 220 0.145
Human
epidermis development GO:0008544 187 0.144
Human
protein processing GO:0016485 163 0.142
phospholipid metabolic process GO:0006644 87 0.141
regulation of t cell activation GO:0050863 170 0.140
regulation of cellular ketone metabolic process GO:0010565 66 0.139
cytokine mediated signaling pathway GO:0019221 115 0.121
regulation of secretion GO:0051046 274 0.119
epidermis morphogenesis GO:0048730 33 0.116
regulation of keratinocyte differentiation GO:0045616 11 0.113
regulation of transferase activity GO:0051338 263 0.110
exocytosis GO:0006887 121 0.107
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.107
positive regulation of cellular amine metabolic process GO:0033240 5 0.106
regulation of system process GO:0044057 200 0.106
regulation of cell activation GO:0050865 289 0.101
transmission of nerve impulse GO:0019226 76 0.098
regulation of cellular amine metabolic process GO:0033238 20 0.097
macromolecule catabolic process GO:0009057 281 0.094
keratinization GO:0031424 9 0.093
stem cell differentiation GO:0048863 268 0.088
regulation of kinase activity GO:0043549 249 0.086
urogenital system development GO:0001655 261 0.085
gland development GO:0048732 330 0.084
negative regulation of cell proliferation GO:0008285 296 0.082
multicellular organismal signaling GO:0035637 91 0.078
glucose transport GO:0015758 56 0.076
leukocyte homeostasis GO:0001776 79 0.075
regulation of proteolysis GO:0030162 164 0.074
response to inorganic substance GO:0010035 96 0.074
extrinsic apoptotic signaling pathway GO:0097191 126 0.071
monosaccharide transport GO:0015749 58 0.071
oxidation reduction process GO:0055114 342 0.070
regulation of protein transport GO:0051223 163 0.069
hormone secretion GO:0046879 128 0.066
peptidyl tyrosine modification GO:0018212 145 0.063
regulation of leukocyte differentiation GO:1902105 159 0.063
regulation of hormone levels GO:0010817 211 0.062
positive regulation of transferase activity GO:0051347 167 0.061
peptidyl amino acid modification GO:0018193 336 0.061
regulation of t cell differentiation GO:0045580 83 0.060
cellular response to hormone stimulus GO:0032870 150 0.055
cellular modified amino acid metabolic process GO:0006575 63 0.054
inflammatory response GO:0006954 244 0.054
response to acid chemical GO:0001101 111 0.053
fertilization GO:0009566 127 0.050
epithelial cell proliferation GO:0050673 174 0.050
multicellular organism growth GO:0035264 161 0.049
positive regulation of vasoconstriction GO:0045907 4 0.049
skin morphogenesis GO:0043589 38 0.049
molting cycle GO:0042303 90 0.049
regulation of lymphocyte differentiation GO:0045619 107 0.048
homeostasis of number of cells GO:0048872 210 0.048
hexose transport GO:0008645 56 0.048
compound eye development GO:0048749 1 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.045
regulation of peptidase activity GO:0052547 96 0.044
regulation of epidermis development GO:0045682 33 0.043
regulation of hormone secretion GO:0046883 88 0.043
hormone metabolic process GO:0042445 86 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
negative regulation of cell activation GO:0050866 111 0.040
peptide transport GO:0015833 133 0.040
stem cell development GO:0048864 219 0.040
amide transport GO:0042886 138 0.040
cation homeostasis GO:0055080 212 0.039
regulation of cellular catabolic process GO:0031329 242 0.038
positive regulation of programmed cell death GO:0043068 218 0.038
cation transport GO:0006812 399 0.038
carboxylic acid transport GO:0046942 100 0.038
intermediate filament organization GO:0045109 15 0.037
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.037
response to light stimulus GO:0009416 135 0.037
carbohydrate transport GO:0008643 62 0.037
regulation of endopeptidase activity GO:0052548 89 0.037
amine metabolic process GO:0009308 45 0.037
neuronal action potential GO:0019228 54 0.036
glial cell development GO:0021782 54 0.036
peptidyl tyrosine phosphorylation GO:0018108 143 0.035
interleukin 13 secretion GO:0072611 2 0.035
t cell activation GO:0042110 289 0.035
ensheathment of neurons GO:0007272 76 0.035
peptide secretion GO:0002790 114 0.035
regulation of lymphocyte activation GO:0051249 240 0.035
organic hydroxy compound metabolic process GO:1901615 203 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
negative regulation of multi organism process GO:0043901 68 0.034
response to nutrient levels GO:0031667 109 0.034
positive regulation of leukocyte differentiation GO:1902107 86 0.034
hepatocyte apoptotic process GO:0097284 11 0.033
negative regulation of cellular amine metabolic process GO:0033239 1 0.033
carbohydrate metabolic process GO:0005975 230 0.033
organonitrogen compound biosynthetic process GO:1901566 192 0.033
positive regulation of epidermis development GO:0045684 13 0.033
endothelium development GO:0003158 45 0.032
sulfur compound metabolic process GO:0006790 100 0.032
regulation of protein kinase activity GO:0045859 232 0.032
sodium ion transport GO:0006814 73 0.032
epinephrine transport GO:0048241 1 0.032
small gtpase mediated signal transduction GO:0007264 97 0.032
carboxylic acid biosynthetic process GO:0046394 86 0.032
zymogen activation GO:0031638 41 0.031
adiponectin secretion GO:0070162 2 0.031
regulation of transmembrane transport GO:0034762 128 0.031
muscle tissue development GO:0060537 308 0.031
response to extracellular stimulus GO:0009991 127 0.030
protein catabolic process GO:0030163 221 0.030
inorganic cation transmembrane transport GO:0098662 207 0.029
regulation of antimicrobial peptide production GO:0002784 1 0.029
carbohydrate homeostasis GO:0033500 128 0.029
peptide hormone secretion GO:0030072 109 0.029
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.028
cation transmembrane transport GO:0098655 266 0.028
wound healing GO:0042060 157 0.028
defense response to other organism GO:0098542 197 0.028
glucose homeostasis GO:0042593 128 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
organic acid biosynthetic process GO:0016053 86 0.027
defense response to virus GO:0051607 68 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
apoptotic mitochondrial changes GO:0008637 48 0.027
regulation of intracellular transport GO:0032386 159 0.026
response to organic cyclic compound GO:0014070 198 0.026
aromatic compound catabolic process GO:0019439 286 0.026
cellular response to cytokine stimulus GO:0071345 189 0.026
nitrogen compound transport GO:0071705 271 0.025
cell type specific apoptotic process GO:0097285 268 0.025
signal transduction in absence of ligand GO:0038034 55 0.025
positive regulation of kinase activity GO:0033674 155 0.025
negative regulation of interleukin 5 production GO:0032714 4 0.025
insulin secretion GO:0030073 89 0.025
male gamete generation GO:0048232 285 0.025
adaptive immune response GO:0002250 155 0.024
phenol containing compound metabolic process GO:0018958 60 0.024
response to lipopolysaccharide GO:0032496 128 0.024
potassium ion transport GO:0006813 52 0.024
positive regulation of protein kinase activity GO:0045860 144 0.023
blastocyst development GO:0001824 80 0.023
regulation of cellular response to insulin stimulus GO:1900076 30 0.023
regulation of systemic arterial blood pressure GO:0003073 61 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
cellular potassium ion transport GO:0071804 43 0.023
retina development in camera type eye GO:0060041 119 0.023
binding of sperm to zona pellucida GO:0007339 34 0.023
negative regulation of molecular function GO:0044092 258 0.022
heart morphogenesis GO:0003007 178 0.022
positive regulation of t cell differentiation GO:0045582 52 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.022
response to insulin GO:0032868 100 0.022
release of cytochrome c from mitochondria GO:0001836 23 0.022
regulation of interleukin 13 secretion GO:2000665 2 0.022
regulation of protein localization GO:0032880 231 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
interleukin 5 secretion GO:0072603 2 0.021
glycoprotein metabolic process GO:0009100 116 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
lipid biosynthetic process GO:0008610 179 0.021
reflex GO:0060004 22 0.021
regulation of tube size GO:0035150 57 0.021
lung epithelium development GO:0060428 37 0.021
t cell differentiation GO:0030217 174 0.021
lymphocyte homeostasis GO:0002260 64 0.021
lipid localization GO:0010876 126 0.020
protein kinase b signaling GO:0043491 74 0.020
regulation of blood vessel size GO:0050880 56 0.020
regulation of androgen receptor signaling pathway GO:0060765 3 0.020
epithelial cell maturation GO:0002070 15 0.020
adult behavior GO:0030534 135 0.020
cellular response to glucocorticoid stimulus GO:0071385 13 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
negative regulation of epithelial cell proliferation GO:0050680 64 0.020
cytokine production GO:0001816 319 0.019
heterocycle catabolic process GO:0046700 280 0.019
myelination GO:0042552 74 0.019
muscle cell differentiation GO:0042692 261 0.019
translation GO:0006412 93 0.019
regulation of metal ion transport GO:0010959 106 0.019
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.019
cellular response to lipid GO:0071396 145 0.019
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.019
protein autoprocessing GO:0016540 2 0.018
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
regulation of cytokine production GO:0001817 266 0.018
fatty acid biosynthetic process GO:0006633 41 0.018
ras protein signal transduction GO:0007265 77 0.018
anion transport GO:0006820 177 0.018
regulation of protein catabolic process GO:0042176 108 0.018
cellular lipid metabolic process GO:0044255 323 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
negative regulation of interleukin 13 secretion GO:2000666 1 0.018
cholesterol homeostasis GO:0042632 44 0.018
blastocyst growth GO:0001832 23 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
thyroid hormone metabolic process GO:0042403 16 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.017
response to metal ion GO:0010038 47 0.017
cellular ion homeostasis GO:0006873 165 0.017
positive regulation of proteolysis GO:0045862 85 0.017
lung epithelial cell differentiation GO:0060487 29 0.017
glycerolipid metabolic process GO:0046486 122 0.017
digestive system development GO:0055123 200 0.017
vascular process in circulatory system GO:0003018 62 0.017
syncytium formation GO:0006949 43 0.017
unsaturated fatty acid metabolic process GO:0033559 31 0.017
negative regulation of lymphocyte differentiation GO:0045620 32 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
regulation of hydrolase activity GO:0051336 246 0.017
positive regulation of response to wounding GO:1903036 66 0.017
cell fate commitment GO:0045165 210 0.016
regulation of interleukin 5 secretion GO:2000662 2 0.016
response to endoplasmic reticulum stress GO:0034976 53 0.016
respiratory tube development GO:0030323 167 0.016
regulation of peptide secretion GO:0002791 77 0.016
response to testosterone GO:0033574 3 0.016
organic acid transport GO:0015849 101 0.016
protein oligomerization GO:0051259 67 0.016
Human
positive regulation of apoptotic process GO:0043065 217 0.016
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.016
lung alveolus development GO:0048286 45 0.016
protein localization to membrane GO:0072657 108 0.015
glial cell differentiation GO:0010001 131 0.015
cellular response to antibiotic GO:0071236 4 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
regulation of secretion by cell GO:1903530 249 0.015
organophosphate catabolic process GO:0046434 232 0.015
regulation of protein processing GO:0070613 96 0.015
negative regulation of kinase activity GO:0033673 81 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
lung cell differentiation GO:0060479 30 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
skeletal system development GO:0001501 356 0.015
regulation of defense response GO:0031347 233 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
regulation of saliva secretion GO:0046877 2 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
response to organonitrogen compound GO:0010243 246 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
positive regulation of t cell activation GO:0050870 101 0.015
regulation of receptor activity GO:0010469 41 0.014
cellularization GO:0007349 1 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
cellular response to glucose stimulus GO:0071333 45 0.014
negative regulation of interleukin 13 production GO:0032696 2 0.014
positive regulation of cytokine production GO:0001819 174 0.014
cellular response to inorganic substance GO:0071241 37 0.014
action potential GO:0001508 78 0.014
tyrosine phosphorylation of stat protein GO:0007260 23 0.014
response to drug GO:0042493 75 0.014
respiratory system development GO:0060541 190 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
syncytium formation by plasma membrane fusion GO:0000768 42 0.014
negative regulation of leukocyte differentiation GO:1902106 51 0.014
anatomical structure homeostasis GO:0060249 145 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
negative regulation of secretion by cell GO:1903531 54 0.014
positive regulation of protein modification process GO:0031401 299 0.014
positive regulation of secretion GO:0051047 130 0.013
endocrine process GO:0050886 39 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
negative regulation of protein modification process GO:0031400 163 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
macromolecule methylation GO:0043414 120 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of inflammatory response GO:0050727 147 0.013
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
fat cell differentiation GO:0045444 160 0.013
regulation of lipid transport GO:0032368 36 0.013
interspecies interaction between organisms GO:0044419 83 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.013
intracellular protein transport GO:0006886 204 0.013
lipid homeostasis GO:0055088 63 0.013
membrane organization GO:0061024 245 0.013
protein secretion GO:0009306 111 0.013
er nucleus signaling pathway GO:0006984 27 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
hair follicle development GO:0001942 85 0.013
myeloid cell homeostasis GO:0002262 114 0.013
divalent inorganic cation transport GO:0072511 178 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
regulation of glucose transport GO:0010827 32 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
cell maturation GO:0048469 127 0.013
regulation of ion transport GO:0043269 215 0.013
branching involved in prostate gland morphogenesis GO:0060442 15 0.013
negative regulation of proteolysis GO:0045861 74 0.013
histone modification GO:0016570 159 0.012
adult locomotory behavior GO:0008344 91 0.012
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.012
myeloid cell differentiation GO:0030099 233 0.012
dna metabolic process GO:0006259 303 0.012
regulated secretory pathway GO:0045055 32 0.012
lung development GO:0030324 164 0.012
lung secretory cell differentiation GO:0061140 13 0.012
regulation of feeding behavior GO:0060259 3 0.012
lymphocyte differentiation GO:0030098 242 0.012
cellular homeostasis GO:0019725 240 0.012
t helper 2 cell cytokine production GO:0035745 4 0.012
sterol homeostasis GO:0055092 45 0.012
cellular response to carbohydrate stimulus GO:0071322 50 0.012
organ growth GO:0035265 117 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
chromatin organization GO:0006325 206 0.012
regulation of epidermal cell differentiation GO:0045604 21 0.012
antimicrobial peptide production GO:0002775 2 0.012
negative regulation of response to wounding GO:1903035 77 0.012
positive regulation of transcription via serum response element binding GO:0010735 1 0.012
smoothened signaling pathway GO:0007224 105 0.012
chromatin modification GO:0016568 187 0.012
regulation of muscle tissue development GO:1901861 97 0.012
response to radiation GO:0009314 165 0.012
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.012
camera type eye development GO:0043010 266 0.012
negative regulation of growth GO:0045926 99 0.012
methylation GO:0032259 134 0.012
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.012
negative regulation of t cell activation GO:0050868 65 0.011
peptidyl serine modification GO:0018209 83 0.011
response to peptide hormone GO:0043434 127 0.011
negative regulation of interleukin 5 secretion GO:2000663 1 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
single fertilization GO:0007338 82 0.011
b cell differentiation GO:0030183 78 0.011
axon ensheathment GO:0008366 76 0.011
regulation of translation GO:0006417 71 0.011
neuroblast differentiation GO:0014016 2 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of cell migration GO:0030334 219 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.011
defense response to bacterium GO:0042742 119 0.011
heart process GO:0003015 94 0.011
protein alkylation GO:0008213 81 0.011
ion transmembrane transport GO:0034220 361 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of antibacterial peptide production GO:0002786 1 0.011
regulation of protein secretion GO:0050708 82 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
regulation of map kinase activity GO:0043405 120 0.011
negative regulation of macrophage activation GO:0043031 2 0.011
regulation of peptide hormone secretion GO:0090276 75 0.011
positive regulation of cell activation GO:0050867 158 0.011
intracellular mrna localization GO:0008298 4 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
t cell apoptotic process GO:0070231 39 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
organelle assembly GO:0070925 177 0.010
sensory perception of light stimulus GO:0050953 54 0.010
cytokine secretion GO:0050663 72 0.010
positive regulation of glycolytic process GO:0045821 4 0.010
mapk cascade GO:0000165 281 0.010
negative regulation of histone h3 k9 methylation GO:0051573 4 0.010
cytokine metabolic process GO:0042107 71 0.010
cellular glucan metabolic process GO:0006073 32 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
innate immune response GO:0045087 157 0.010

Tgm3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.028
disease of anatomical entity DOID:7 0 0.028
inherited metabolic disorder DOID:655 0 0.016
disease of metabolism DOID:0014667 0 0.016
central nervous system disease DOID:331 0 0.014