Mus musculus

0 known processes

Tgm6

transglutaminase 6

(Aliases: A030011P16,TGM3L,TGY)

Tgm6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.117
regulation of cellular ketone metabolic process GO:0010565 66 0.068
epidermis development GO:0008544 187 0.068
cellular amino acid metabolic process GO:0006520 103 0.066
cellular amine metabolic process GO:0044106 44 0.063
wnt signaling pathway GO:0016055 188 0.060
epithelial cell development GO:0002064 159 0.054
developmental maturation GO:0021700 193 0.051
small gtpase mediated signal transduction GO:0007264 97 0.049
macromolecule catabolic process GO:0009057 281 0.046
cell type specific apoptotic process GO:0097285 268 0.046
blood vessel morphogenesis GO:0048514 285 0.045
muscle tissue development GO:0060537 308 0.045
extracellular matrix organization GO:0030198 147 0.043
striated muscle tissue development GO:0014706 293 0.042
negative regulation of neuron differentiation GO:0045665 101 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
response to molecule of bacterial origin GO:0002237 143 0.039
angiogenesis GO:0001525 201 0.038
amine metabolic process GO:0009308 45 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.037
peptidyl amino acid modification GO:0018193 336 0.036
regulation of lipid metabolic process GO:0019216 118 0.036
stem cell development GO:0048864 219 0.036
skeletal system development GO:0001501 356 0.035
placenta development GO:0001890 140 0.034
canonical wnt signaling pathway GO:0060070 130 0.034
negative regulation of growth GO:0045926 99 0.033
regulation of defense response GO:0031347 233 0.033
regulation of cell projection organization GO:0031344 206 0.032
carbohydrate metabolic process GO:0005975 230 0.030
regulation of secretion GO:0051046 274 0.030
multi multicellular organism process GO:0044706 109 0.030
negative regulation of nervous system development GO:0051961 156 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.030
regulation of protein localization GO:0032880 231 0.030
apoptotic signaling pathway GO:0097190 306 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
negative regulation of molecular function GO:0044092 258 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
axonogenesis GO:0007409 274 0.029
stem cell differentiation GO:0048863 268 0.029
negative regulation of phosphorylation GO:0042326 166 0.028
positive regulation of protein modification process GO:0031401 299 0.028
small molecule biosynthetic process GO:0044283 132 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
protein processing GO:0016485 163 0.027
gland development GO:0048732 330 0.027
protein catabolic process GO:0030163 221 0.027
cellular ketone metabolic process GO:0042180 84 0.027
regulation of anatomical structure size GO:0090066 178 0.027
urogenital system development GO:0001655 261 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.026
alcohol metabolic process GO:0006066 116 0.026
muscle cell differentiation GO:0042692 261 0.026
ossification GO:0001503 216 0.026
renal system development GO:0072001 225 0.026
developmental growth involved in morphogenesis GO:0060560 138 0.026
inflammatory response GO:0006954 244 0.026
cellular response to cytokine stimulus GO:0071345 189 0.026
regulation of neuron projection development GO:0010975 169 0.025
protein maturation GO:0051604 176 0.025
extracellular structure organization GO:0043062 148 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
morphogenesis of a branching structure GO:0001763 203 0.025
response to nutrient levels GO:0031667 109 0.025
glycerolipid metabolic process GO:0046486 122 0.025
bone development GO:0060348 120 0.025
regulation of neuron differentiation GO:0045664 281 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
ras protein signal transduction GO:0007265 77 0.024
regulation of transferase activity GO:0051338 263 0.024
camera type eye development GO:0043010 266 0.024
regulation of canonical wnt signaling pathway GO:0060828 82 0.023
organic hydroxy compound biosynthetic process GO:1901617 77 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
fat cell differentiation GO:0045444 160 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
cellular homeostasis GO:0019725 240 0.023
stem cell proliferation GO:0072089 117 0.022
embryonic placenta development GO:0001892 98 0.022
cellular response to biotic stimulus GO:0071216 92 0.022
negative regulation of cell development GO:0010721 169 0.021
lipid biosynthetic process GO:0008610 179 0.021
skeletal system morphogenesis GO:0048705 203 0.021
phospholipid metabolic process GO:0006644 87 0.021
cell maturation GO:0048469 127 0.021
regulation of cell motility GO:2000145 236 0.021
dna metabolic process GO:0006259 303 0.021
regulation of vasculature development GO:1901342 88 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
positive regulation of nervous system development GO:0051962 221 0.021
epithelial cell proliferation GO:0050673 174 0.021
response to organonitrogen compound GO:0010243 246 0.021
developmental cell growth GO:0048588 84 0.020
immune effector process GO:0002252 321 0.020
leukocyte differentiation GO:0002521 342 0.020
mesenchymal cell differentiation GO:0048762 107 0.020
regulation of peptidase activity GO:0052547 96 0.020
positive regulation of stem cell proliferation GO:2000648 59 0.020
leukocyte migration GO:0050900 124 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
regulation of stem cell proliferation GO:0072091 78 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
regulation of protein transport GO:0051223 163 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
neuron death GO:0070997 154 0.019
somatotropin secreting cell differentiation GO:0060126 4 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
heart morphogenesis GO:0003007 178 0.019
response to organic cyclic compound GO:0014070 198 0.019
cytoplasmic transport GO:0016482 234 0.019
nucleoside metabolic process GO:0009116 246 0.019
regulation of cell migration GO:0030334 219 0.019
single organismal cell cell adhesion GO:0016337 131 0.019
regulation of mapk cascade GO:0043408 248 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
regulation of muscle tissue development GO:1901861 97 0.019
digestive tract morphogenesis GO:0048546 147 0.019
oxidation reduction process GO:0055114 342 0.018
purine containing compound metabolic process GO:0072521 311 0.018
regulation of neural precursor cell proliferation GO:2000177 70 0.018
kidney development GO:0001822 213 0.018
innate immune response GO:0045087 157 0.018
membrane organization GO:0061024 245 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
cytokine production GO:0001816 319 0.018
spinal cord development GO:0021510 81 0.018
striated muscle cell development GO:0055002 125 0.018
chemotaxis GO:0006935 247 0.018
hair follicle development GO:0001942 85 0.018
positive regulation of cytokine production GO:0001819 174 0.018
heterocycle catabolic process GO:0046700 280 0.018
hair cycle GO:0042633 90 0.018
nucleotide metabolic process GO:0009117 332 0.018
regulation of proteolysis GO:0030162 164 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
regulation of cell growth GO:0001558 91 0.017
myeloid cell differentiation GO:0030099 233 0.017
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
regulation of cellular response to growth factor stimulus GO:0090287 82 0.017
mapk cascade GO:0000165 281 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
endocrine system development GO:0035270 98 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
regulation of cell cycle GO:0051726 281 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of neuron projection development GO:0010977 50 0.017
protein localization to organelle GO:0033365 185 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
mesodermal cell migration GO:0008078 4 0.017
regulation of interleukin 8 secretion GO:2000482 2 0.017
digestive system development GO:0055123 200 0.016
tissue remodeling GO:0048771 102 0.016
negative regulation of cell projection organization GO:0031345 56 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
neural precursor cell proliferation GO:0061351 121 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
lipid transport GO:0006869 98 0.016
chondrocyte differentiation GO:0002062 72 0.016
skin development GO:0043588 220 0.016
negative regulation of response to wounding GO:1903035 77 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
blood circulation GO:0008015 195 0.016
negative regulation of cell cycle GO:0045786 123 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
sterol metabolic process GO:0016125 58 0.016
response to extracellular stimulus GO:0009991 127 0.016
regulation of kinase activity GO:0043549 249 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of cytokine production GO:0001817 266 0.016
mitotic cell cycle GO:0000278 195 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
cell growth GO:0016049 130 0.016
female sex differentiation GO:0046660 84 0.016
cardiac chamber development GO:0003205 108 0.016
regulation of epidermis development GO:0045682 33 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
multicellular organism growth GO:0035264 161 0.015
epidermis morphogenesis GO:0048730 33 0.015
response to inorganic substance GO:0010035 96 0.015
negative regulation of wnt signaling pathway GO:0030178 73 0.015
sequestering of calcium ion GO:0051208 18 0.015
neuron apoptotic process GO:0051402 142 0.015
organ growth GO:0035265 117 0.015
blastocyst development GO:0001824 80 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
synapse organization GO:0050808 125 0.015
positive regulation of cell motility GO:2000147 116 0.015
development of primary sexual characteristics GO:0045137 143 0.015
protein secretion GO:0009306 111 0.015
respiratory tube development GO:0030323 167 0.015
negative regulation of protein modification process GO:0031400 163 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
mesenchyme development GO:0060485 152 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
homeostasis of number of cells GO:0048872 210 0.015
ameboidal type cell migration GO:0001667 128 0.015
translation GO:0006412 93 0.015
organophosphate catabolic process GO:0046434 232 0.015
forebrain development GO:0030900 302 0.015
chromatin modification GO:0016568 187 0.015
wound healing GO:0042060 157 0.015
response to peptide GO:1901652 136 0.014
cellular response to lipid GO:0071396 145 0.014
cell differentiation involved in embryonic placenta development GO:0060706 26 0.014
regulation of body fluid levels GO:0050878 162 0.014
cardiac ventricle development GO:0003231 83 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
single organism cell adhesion GO:0098602 156 0.014
nucleotide catabolic process GO:0009166 217 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
regulation of organelle organization GO:0033043 289 0.014
male gamete generation GO:0048232 285 0.014
lipid catabolic process GO:0016042 69 0.014
nitrogen compound transport GO:0071705 271 0.014
mesenchymal cell development GO:0014031 93 0.014
regulation of interleukin 10 secretion GO:2001179 4 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
gonad development GO:0008406 141 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
compound eye development GO:0048749 1 0.014
fatty acid metabolic process GO:0006631 121 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
endodermal cell fate specification GO:0001714 4 0.013
rna interference GO:0016246 2 0.013
anion transport GO:0006820 177 0.013
alcohol biosynthetic process GO:0046165 43 0.013
chromatin organization GO:0006325 206 0.013
regulation of hydrolase activity GO:0051336 246 0.013
cell adhesion GO:0007155 329 0.013
cholesterol metabolic process GO:0008203 56 0.013
positive regulation of growth GO:0045927 104 0.013
sensory perception GO:0007600 245 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
circulatory system process GO:0003013 197 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
cation homeostasis GO:0055080 212 0.013
embryonic appendage morphogenesis GO:0035113 126 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
organelle localization GO:0051640 179 0.013
microtubule based process GO:0007017 236 0.013
aromatic compound catabolic process GO:0019439 286 0.013
intermediate filament based process GO:0045103 27 0.013
lipoprotein metabolic process GO:0042157 43 0.013
nuclear transport GO:0051169 139 0.013
establishment of protein localization to organelle GO:0072594 118 0.012
telencephalon development GO:0021537 186 0.012
cellular ion homeostasis GO:0006873 165 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
regulation of angiogenesis GO:0045765 81 0.012
myotube differentiation GO:0014902 105 0.012
regulation of hormone levels GO:0010817 211 0.012
positive regulation of cell activation GO:0050867 158 0.012
regulation of extent of cell growth GO:0061387 52 0.012
steroid metabolic process GO:0008202 119 0.012
cation transport GO:0006812 399 0.012
protein ubiquitination GO:0016567 171 0.012
appendage development GO:0048736 166 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
nephron development GO:0072006 109 0.012
cardiac muscle tissue development GO:0048738 130 0.012
bone morphogenesis GO:0060349 78 0.012
adult behavior GO:0030534 135 0.012
stem cell maintenance GO:0019827 130 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
cell fate commitment GO:0045165 210 0.012
purine containing compound catabolic process GO:0072523 213 0.012
regulation of protein catabolic process GO:0042176 108 0.012
interleukin 10 secretion GO:0072608 4 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
organic acid biosynthetic process GO:0016053 86 0.012
male gonad development GO:0008584 88 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
neuron migration GO:0001764 122 0.012
defecation GO:0030421 1 0.012
regulation of secretion by cell GO:1903530 249 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
positive regulation of protein transport GO:0051222 93 0.012
fertilization GO:0009566 127 0.012
regulation of system process GO:0044057 200 0.012
cellular response to inorganic substance GO:0071241 37 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
response to lipopolysaccharide GO:0032496 128 0.012
muscle cell development GO:0055001 133 0.012
regulation of metal ion transport GO:0010959 106 0.012
appendage morphogenesis GO:0035107 149 0.012
lung development GO:0030324 164 0.011
protein localization to membrane GO:0072657 108 0.011
detection of molecule of bacterial origin GO:0032490 2 0.011
epithelial to mesenchymal transition GO:0001837 47 0.011
maintenance of location GO:0051235 89 0.011
regulation of ossification GO:0030278 112 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
heart contraction GO:0060047 93 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
divalent inorganic cation transport GO:0072511 178 0.011
negative regulation of endothelial cell migration GO:0010596 4 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
keratinocyte differentiation GO:0030216 48 0.011
axis elongation involved in somitogenesis GO:0090245 4 0.011
regulation of cell adhesion GO:0030155 154 0.011
metanephros development GO:0001656 79 0.011
neuron projection extension GO:1990138 64 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
regulation of heart growth GO:0060420 31 0.011
regulation of protein kinase activity GO:0045859 232 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
skeletal muscle cell differentiation GO:0035914 66 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
protein localization to nucleus GO:0034504 121 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
lens development in camera type eye GO:0002088 62 0.011
biomineral tissue development GO:0031214 64 0.011
regionalization GO:0003002 337 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
cartilage development GO:0051216 140 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
cell proliferation in hindbrain GO:0021534 10 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
gastrulation GO:0007369 116 0.011
retina development in camera type eye GO:0060041 119 0.011
respiratory system development GO:0060541 190 0.011
ear development GO:0043583 200 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
regulation of transforming growth factor beta secretion GO:2001201 1 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
response to metal ion GO:0010038 47 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of membrane potential GO:0042391 192 0.011
asymmetric neuroblast division GO:0055059 1 0.011
t cell differentiation GO:0030217 174 0.010
protein targeting GO:0006605 143 0.010
heart process GO:0003015 94 0.010
amide transport GO:0042886 138 0.010
nuclear import GO:0051170 95 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
development of primary female sexual characteristics GO:0046545 73 0.010
regulation of protein secretion GO:0050708 82 0.010
regulation of protein maturation GO:1903317 96 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
t cell activation GO:0042110 289 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010
protein glycosylation GO:0006486 55 0.010
calcium ion homeostasis GO:0055074 127 0.010
regulation of cellular response to stress GO:0080135 159 0.010
defense response to other organism GO:0098542 197 0.010
palate development GO:0060021 76 0.010
regulation of protein processing GO:0070613 96 0.010
lymphocyte proliferation GO:0046651 164 0.010
tissue migration GO:0090130 68 0.010
positive regulation of secretion GO:0051047 130 0.010
regulation of fat cell differentiation GO:0045598 81 0.010
positive regulation of striated muscle tissue development GO:0045844 31 0.010
glycoprotein metabolic process GO:0009100 116 0.010
connective tissue development GO:0061448 179 0.010
cell recognition GO:0008037 83 0.010
cell activation involved in immune response GO:0002263 126 0.010
carbohydrate homeostasis GO:0033500 128 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
positive regulation of transferase activity GO:0051347 167 0.010
interleukin 8 secretion GO:0072606 3 0.010
tube formation GO:0035148 140 0.010
response to acid chemical GO:0001101 111 0.010
skin morphogenesis GO:0043589 38 0.010
negative regulation of immune system process GO:0002683 209 0.010
mammary gland epithelium development GO:0061180 65 0.010
midgut development GO:0007494 4 0.010
epithelial cell morphogenesis GO:0003382 41 0.010

Tgm6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.012