Mus musculus

44 known processes

Sh3yl1

Sh3 domain YSC-like 1

(Aliases: YSC84,MGC118159,Ray,AI314953)

Sh3yl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.067
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
protein catabolic process GO:0030163 221 0.044
amine metabolic process GO:0009308 45 0.043
cellular amine metabolic process GO:0044106 44 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
macromolecule catabolic process GO:0009057 281 0.041
cellular ketone metabolic process GO:0042180 84 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.038
regulation of proteolysis GO:0030162 164 0.036
organic hydroxy compound metabolic process GO:1901615 203 0.036
aromatic compound catabolic process GO:0019439 286 0.036
transmembrane transport GO:0055085 412 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.033
nitrogen compound transport GO:0071705 271 0.033
cellular lipid metabolic process GO:0044255 323 0.033
apoptotic signaling pathway GO:0097190 306 0.033
regulation of cellular catabolic process GO:0031329 242 0.032
cell adhesion GO:0007155 329 0.030
oxidation reduction process GO:0055114 342 0.030
nucleotide catabolic process GO:0009166 217 0.029
monocarboxylic acid metabolic process GO:0032787 191 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
regulation of organelle organization GO:0033043 289 0.028
lipid biosynthetic process GO:0008610 179 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
nucleoside metabolic process GO:0009116 246 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
cell type specific apoptotic process GO:0097285 268 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
organic cyclic compound catabolic process GO:1901361 295 0.025
male gamete generation GO:0048232 285 0.025
spermatogenesis GO:0007283 284 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
myeloid cell differentiation GO:0030099 233 0.024
cation transport GO:0006812 399 0.024
regulation of hydrolase activity GO:0051336 246 0.024
cytoplasmic transport GO:0016482 234 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
purine containing compound catabolic process GO:0072523 213 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
response to acid chemical GO:0001101 111 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
small molecule biosynthetic process GO:0044283 132 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
heterocycle catabolic process GO:0046700 280 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
wnt signaling pathway GO:0016055 188 0.023
response to organonitrogen compound GO:0010243 246 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
organophosphate catabolic process GO:0046434 232 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
regulation of neuron projection development GO:0010975 169 0.021
homeostasis of number of cells GO:0048872 210 0.021
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.021
protein maturation GO:0051604 176 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
multicellular organismal signaling GO:0035637 91 0.021
regulation of protein catabolic process GO:0042176 108 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
lipid transport GO:0006869 98 0.021
organelle assembly GO:0070925 177 0.021
muscle tissue development GO:0060537 308 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
negative regulation of molecular function GO:0044092 258 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
anion transport GO:0006820 177 0.021
regulation of cell activation GO:0050865 289 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
camera type eye development GO:0043010 266 0.021
sensory organ morphogenesis GO:0090596 242 0.020
regulation of hormone levels GO:0010817 211 0.020
rho protein signal transduction GO:0007266 32 0.020
regulation of neuron differentiation GO:0045664 281 0.020
leukocyte differentiation GO:0002521 342 0.020
positive regulation of protein modification process GO:0031401 299 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
immune effector process GO:0002252 321 0.020
intracellular protein transport GO:0006886 204 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
response to organic cyclic compound GO:0014070 198 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
epidermis development GO:0008544 187 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
nucleotide metabolic process GO:0009117 332 0.020
peptidyl amino acid modification GO:0018193 336 0.020
regulation of cell adhesion GO:0030155 154 0.020
organic acid biosynthetic process GO:0016053 86 0.020
positive regulation of cell death GO:0010942 224 0.019
regulation of membrane potential GO:0042391 192 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
cation transmembrane transport GO:0098655 266 0.019
skin development GO:0043588 220 0.019
sensory perception GO:0007600 245 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
purine containing compound metabolic process GO:0072521 311 0.019
asymmetric stem cell division GO:0098722 3 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
epithelial cell proliferation GO:0050673 174 0.019
innate immune response GO:0045087 157 0.019
axonogenesis GO:0007409 274 0.019
cellular response to lipid GO:0071396 145 0.019
locomotory behavior GO:0007626 195 0.019
cellular homeostasis GO:0019725 240 0.018
positive regulation of cell development GO:0010720 237 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
cytokine production GO:0001816 319 0.018
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
nucleoside catabolic process GO:0009164 206 0.018
organic anion transport GO:0015711 137 0.018
cell cell junction organization GO:0045216 72 0.018
single organism cell adhesion GO:0098602 156 0.018
regulation of transferase activity GO:0051338 263 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.018
t cell activation GO:0042110 289 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
positive regulation of proteolysis GO:0045862 85 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
transmission of nerve impulse GO:0019226 76 0.017
renal system development GO:0072001 225 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
regulation of t cell activation GO:0050863 170 0.017
peptide transport GO:0015833 133 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
regulation of kinase activity GO:0043549 249 0.017
action potential GO:0001508 78 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
mapk cascade GO:0000165 281 0.017
compound eye development GO:0048749 1 0.017
regulation of ion transport GO:0043269 215 0.016
protein ubiquitination GO:0016567 171 0.016
carbohydrate metabolic process GO:0005975 230 0.016
developmental maturation GO:0021700 193 0.016
regulation of secretion GO:0051046 274 0.016
respiratory system development GO:0060541 190 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
regulation of cell cycle GO:0051726 281 0.016
response to extracellular stimulus GO:0009991 127 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
fatty acid metabolic process GO:0006631 121 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
inflammatory response GO:0006954 244 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
digestive tract development GO:0048565 190 0.016
negative regulation of immune system process GO:0002683 209 0.016
cellular protein catabolic process GO:0044257 155 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of secretion by cell GO:1903530 249 0.016
ras protein signal transduction GO:0007265 77 0.016
oocyte construction GO:0007308 2 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
ion transmembrane transport GO:0034220 361 0.015
organic acid transport GO:0015849 101 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
protein processing GO:0016485 163 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
carboxylic acid transport GO:0046942 100 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
spermatid differentiation GO:0048515 115 0.015
skeletal system development GO:0001501 356 0.015
regulation of chloride transport GO:2001225 2 0.015
negative regulation of cell activation GO:0050866 111 0.015
negative regulation of protein modification process GO:0031400 163 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
kidney development GO:0001822 213 0.015
regulation of mapk cascade GO:0043408 248 0.015
lymphocyte proliferation GO:0046651 164 0.015
alcohol metabolic process GO:0006066 116 0.015
synaptic transmission GO:0007268 329 0.015
steroid metabolic process GO:0008202 119 0.015
retrograde transport endosome to golgi GO:0042147 2 0.015
regulation of cytokine production GO:0001817 266 0.015
negative regulation of growth GO:0045926 99 0.014
carbohydrate homeostasis GO:0033500 128 0.014
cofactor metabolic process GO:0051186 80 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
regulation of protein complex assembly GO:0043254 83 0.014
leukocyte proliferation GO:0070661 172 0.014
neuronal action potential GO:0019228 54 0.014
membrane organization GO:0061024 245 0.014
fat cell differentiation GO:0045444 160 0.014
circulatory system process GO:0003013 197 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
chemotaxis GO:0006935 247 0.014
striated muscle tissue development GO:0014706 293 0.014
leukocyte mediated immunity GO:0002443 174 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
extracellular matrix organization GO:0030198 147 0.014
regulation of cell projection organization GO:0031344 206 0.014
blood circulation GO:0008015 195 0.014
regulation of actin filament based process GO:0032970 99 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
germ cell development GO:0007281 185 0.014
sulfur compound metabolic process GO:0006790 100 0.014
endomembrane system organization GO:0010256 147 0.014
spermatid development GO:0007286 108 0.014
defense response to other organism GO:0098542 197 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
regulation of response to wounding GO:1903034 189 0.014
sequestering of calcium ion GO:0051208 18 0.014
endocytosis GO:0006897 168 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
actin cytoskeleton organization GO:0030036 220 0.014
response to inorganic substance GO:0010035 96 0.014
vesicle organization GO:0016050 60 0.014
response to growth factor GO:0070848 198 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
methylation GO:0032259 134 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
oligopeptide transmembrane transport GO:0035672 4 0.013
cellularization GO:0007349 1 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of cell motility GO:2000145 236 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
cellular chemical homeostasis GO:0055082 215 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
cell maturation GO:0048469 127 0.013
urogenital system development GO:0001655 261 0.013
epithelial tube formation GO:0072175 130 0.013
regulation of protein kinase activity GO:0045859 232 0.013
microtubule based process GO:0007017 236 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
regulation of homeostatic process GO:0032844 182 0.013
cell junction maintenance GO:0034331 4 0.013
positive regulation of nervous system development GO:0051962 221 0.013
lateral inhibition GO:0046331 1 0.013
glycerolipid metabolic process GO:0046486 122 0.013
epithelial cell development GO:0002064 159 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
regulation of protein localization GO:0032880 231 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
exocytosis GO:0006887 121 0.013
regionalization GO:0003002 337 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
response to lipopolysaccharide GO:0032496 128 0.013
digestive system development GO:0055123 200 0.013
gtp catabolic process GO:0006184 143 0.013
negative regulation of cell development GO:0010721 169 0.013
cation homeostasis GO:0055080 212 0.013
organelle localization GO:0051640 179 0.013
response to nutrient levels GO:0031667 109 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
regulation of cellular component size GO:0032535 121 0.013
rhythmic process GO:0048511 174 0.013
positive regulation of protein catabolic process GO:0045732 60 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
actin filament organization GO:0007015 113 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
gland development GO:0048732 330 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
response to amino acid GO:0043200 37 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
dna metabolic process GO:0006259 303 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
regulation of cellular response to stress GO:0080135 159 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
divalent inorganic cation transport GO:0072511 178 0.012
neural tube development GO:0021915 160 0.012
adaptive immune response GO:0002250 155 0.012
glucose homeostasis GO:0042593 128 0.012
negative regulation of cell cycle GO:0045786 123 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
actin filament based movement GO:0030048 23 0.012
localization within membrane GO:0051668 4 0.012
nuclear division GO:0000280 158 0.012
regulation of transmembrane transport GO:0034762 128 0.012
positive regulation of cellular ph reduction GO:0032849 2 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
regulation of system process GO:0044057 200 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
regulation of leukocyte proliferation GO:0070663 121 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
tube formation GO:0035148 140 0.011
b cell activation GO:0042113 161 0.011
maintenance of location GO:0051235 89 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
response to oxidative stress GO:0006979 123 0.011
negative regulation of nervous system development GO:0051961 156 0.011
regulation of binding GO:0051098 111 0.011
intracellular mrna localization GO:0008298 4 0.011
neuron death GO:0070997 154 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
lymphocyte differentiation GO:0030098 242 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of intracellular transport GO:0032386 159 0.011
t cell differentiation GO:0030217 174 0.011
protein targeting GO:0006605 143 0.011
erythrocyte differentiation GO:0030218 88 0.011
lung development GO:0030324 164 0.011
fat soluble vitamin biosynthetic process GO:0042362 4 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
positive regulation of secretion GO:0051047 130 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.011
glucose transport GO:0015758 56 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
skeletal muscle organ development GO:0060538 163 0.011
monosaccharide transport GO:0015749 58 0.011
forebrain development GO:0030900 302 0.011
microtubule based movement GO:0007018 84 0.011
establishment of vesicle localization GO:0051650 81 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
hormone secretion GO:0046879 128 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
cellular response to external stimulus GO:0071496 88 0.011
rhodopsin mediated signaling pathway GO:0016056 4 0.011
muscle cell differentiation GO:0042692 261 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
vesicle localization GO:0051648 86 0.011
organelle fission GO:0048285 170 0.011
response to transforming growth factor beta GO:0071559 88 0.011
cellular protein complex assembly GO:0043623 116 0.011
bmp signaling pathway GO:0030509 93 0.011
amide transport GO:0042886 138 0.010
positive regulation of gtp catabolic process GO:0033126 85 0.010
protein localization to vacuole GO:0072665 4 0.010
lipid localization GO:0010876 126 0.010
cytokinetic process GO:0032506 2 0.010
retina development in camera type eye GO:0060041 119 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
chromatin organization GO:0006325 206 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
cellular response to acid chemical GO:0071229 68 0.010
regulation of cell growth GO:0001558 91 0.010
nuclear transport GO:0051169 139 0.010
extracellular structure organization GO:0043062 148 0.010
appendage development GO:0048736 166 0.010
myeloid cell homeostasis GO:0002262 114 0.010
respiratory tube development GO:0030323 167 0.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.010
organ regeneration GO:0031100 2 0.010
microtubule based transport GO:0010970 50 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
placenta development GO:0001890 140 0.010
cellular ion homeostasis GO:0006873 165 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
interleukin 8 production GO:0032637 4 0.010
peptide hormone secretion GO:0030072 109 0.010

Sh3yl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
musculoskeletal system disease DOID:17 0 0.020
central nervous system disease DOID:331 0 0.015
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014
cardiovascular system disease DOID:1287 0 0.012
primary immunodeficiency disease DOID:612 0 0.012
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011
sensory system disease DOID:0050155 0 0.011
disease of metabolism DOID:0014667 0 0.011
muscular disease DOID:0080000 0 0.010