Mus musculus

16 known processes

Igsf8

immunoglobulin superfamily, member 8

(Aliases: KCT-4,PGRL,ESTM34,R75384,AU041109,AA033172,EWI-2)

Igsf8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.155
organic anion transport GO:0015711 137 0.140
transmembrane transport GO:0055085 412 0.127
cellular amine metabolic process GO:0044106 44 0.101
ras protein signal transduction GO:0007265 77 0.099
regulation of membrane potential GO:0042391 192 0.092
rho protein signal transduction GO:0007266 32 0.080
striated muscle contraction GO:0006941 45 0.079
cytoplasmic transport GO:0016482 234 0.074
ribonucleotide metabolic process GO:0009259 291 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.071
locomotory behavior GO:0007626 195 0.071
negative regulation of phosphorus metabolic process GO:0010563 184 0.071
nitrogen compound transport GO:0071705 271 0.068
regulation of cellular amine metabolic process GO:0033238 20 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.065
cation transmembrane transport GO:0098655 266 0.065
cellular metal ion homeostasis GO:0006875 151 0.065
carboxylic acid transport GO:0046942 100 0.064
blood circulation GO:0008015 195 0.062
regulation of secretion GO:0051046 274 0.061
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.059
inorganic cation transmembrane transport GO:0098662 207 0.059
regulation of intracellular transport GO:0032386 159 0.058
small gtpase mediated signal transduction GO:0007264 97 0.058
aromatic compound catabolic process GO:0019439 286 0.058
regulation of apoptotic signaling pathway GO:2001233 197 0.058
cellular calcium ion homeostasis GO:0006874 119 0.056
nucleotide metabolic process GO:0009117 332 0.056
amine metabolic process GO:0009308 45 0.056
regulation of cell projection organization GO:0031344 206 0.055
cellular homeostasis GO:0019725 240 0.055
regulation of neuron differentiation GO:0045664 281 0.055
regulation of purine nucleotide metabolic process GO:1900542 169 0.053
cellular amino acid metabolic process GO:0006520 103 0.053
positive regulation of protein modification process GO:0031401 299 0.052
anion transport GO:0006820 177 0.051
macromolecule glycosylation GO:0043413 55 0.050
cellular ketone metabolic process GO:0042180 84 0.049
glycoprotein biosynthetic process GO:0009101 89 0.049
immune response regulating signaling pathway GO:0002764 125 0.048
protein glycosylation GO:0006486 55 0.048
extrinsic apoptotic signaling pathway GO:0097191 126 0.047
methionine transport GO:0015821 1 0.047
sensory perception GO:0007600 245 0.047
calcium ion homeostasis GO:0055074 127 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
nucleoside phosphate metabolic process GO:0006753 338 0.044
circulatory system process GO:0003013 197 0.044
heart contraction GO:0060047 93 0.044
activation of immune response GO:0002253 138 0.044
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.043
glycosylation GO:0070085 62 0.043
response to growth factor GO:0070848 198 0.042
response to light stimulus GO:0009416 135 0.042
gland development GO:0048732 330 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
skin development GO:0043588 220 0.041
cellular divalent inorganic cation homeostasis GO:0072503 127 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.040
cellular ion homeostasis GO:0006873 165 0.040
protein processing GO:0016485 163 0.040
regulation of ion transport GO:0043269 215 0.040
negative regulation of protein metabolic process GO:0051248 282 0.039
macromolecule catabolic process GO:0009057 281 0.039
purine nucleotide metabolic process GO:0006163 302 0.038
peptidyl tyrosine modification GO:0018212 145 0.038
organic acid transport GO:0015849 101 0.038
cellular chemical homeostasis GO:0055082 215 0.038
carbohydrate metabolic process GO:0005975 230 0.037
rab protein signal transduction GO:0032482 1 0.037
amino acid transport GO:0006865 61 0.036
glycosyl compound catabolic process GO:1901658 206 0.034
response to extracellular stimulus GO:0009991 127 0.034
calcium ion transport GO:0006816 159 0.034
muscle system process GO:0003012 141 0.033
detection of abiotic stimulus GO:0009582 60 0.033
nucleoside metabolic process GO:0009116 246 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
membrane organization GO:0061024 245 0.032
cell type specific apoptotic process GO:0097285 268 0.032
visual perception GO:0007601 52 0.032
positive regulation of nervous system development GO:0051962 221 0.032
cation homeostasis GO:0055080 212 0.032
response to radiation GO:0009314 165 0.031
regulation of chromatin modification GO:1903308 57 0.030
regulation of metal ion transport GO:0010959 106 0.030
respiratory system development GO:0060541 190 0.030
alcohol metabolic process GO:0006066 116 0.029
epidermis development GO:0008544 187 0.029
protein import into nucleus GO:0006606 95 0.029
anion transmembrane transport GO:0098656 71 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.029
sequestering of calcium ion GO:0051208 18 0.029
protein catabolic process GO:0030163 221 0.029
regulation of secretion by cell GO:1903530 249 0.029
skeletal system development GO:0001501 356 0.029
positive regulation of neuron projection development GO:0010976 79 0.029
protein maturation GO:0051604 176 0.028
intracellular protein transport GO:0006886 204 0.028
regulation of protein transport GO:0051223 163 0.028
regulation of nucleotide metabolic process GO:0006140 169 0.028
endocytosis GO:0006897 168 0.028
purine nucleoside metabolic process GO:0042278 241 0.027
retina development in camera type eye GO:0060041 119 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
adult behavior GO:0030534 135 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
bone development GO:0060348 120 0.027
negative regulation of immune system process GO:0002683 209 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
rac protein signal transduction GO:0016601 13 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
neuron death GO:0070997 154 0.026
nucleoside catabolic process GO:0009164 206 0.026
regulation of protein localization GO:0032880 231 0.025
peptide transport GO:0015833 133 0.025
inorganic ion transmembrane transport GO:0098660 234 0.025
peptidyl tyrosine phosphorylation GO:0018108 143 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
protein ubiquitination GO:0016567 171 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
regulation of binding GO:0051098 111 0.024
positive regulation of neuron differentiation GO:0045666 141 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
immune response activating signal transduction GO:0002757 116 0.024
ribonucleoside metabolic process GO:0009119 245 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
leukocyte migration GO:0050900 124 0.023
ameboidal type cell migration GO:0001667 128 0.023
muscle contraction GO:0006936 101 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
peptide secretion GO:0002790 114 0.023
cell substrate adhesion GO:0031589 130 0.023
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.023
regulation of ion transmembrane transport GO:0034765 119 0.022
lytic vacuole organization GO:0080171 21 0.022
positive regulation of nucleoside metabolic process GO:0045979 91 0.022
regulation of cell motility GO:2000145 236 0.022
amide transport GO:0042886 138 0.022
learning or memory GO:0007611 148 0.022
regulation of hydrolase activity GO:0051336 246 0.022
axonogenesis GO:0007409 274 0.022
compound eye development GO:0048749 1 0.022
regulation of calcium ion transport GO:0051924 69 0.022
sensory perception of light stimulus GO:0050953 54 0.022
regulation of cell growth GO:0001558 91 0.021
response to organic cyclic compound GO:0014070 198 0.021
regulation of peptide transport GO:0090087 91 0.021
nuclear import GO:0051170 95 0.021
t cell activation GO:0042110 289 0.021
cell growth GO:0016049 130 0.021
regulation of organelle organization GO:0033043 289 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
glucose homeostasis GO:0042593 128 0.020
regulation of transmembrane transport GO:0034762 128 0.020
negative regulation of neuron apoptotic process GO:0043524 92 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
guanosine containing compound metabolic process GO:1901068 144 0.020
peptide hormone secretion GO:0030072 109 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
positive regulation of cell development GO:0010720 237 0.019
mapk cascade GO:0000165 281 0.019
cation transport GO:0006812 399 0.019
retrograde transport endosome to golgi GO:0042147 2 0.019
epithelial cell development GO:0002064 159 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
cognition GO:0050890 149 0.019
response to lipopolysaccharide GO:0032496 128 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
cytokine mediated signaling pathway GO:0019221 115 0.019
carbohydrate homeostasis GO:0033500 128 0.019
neural tube development GO:0021915 160 0.019
regulation of peptide secretion GO:0002791 77 0.018
hindbrain development GO:0030902 128 0.018
negative regulation of protein maturation GO:1903318 79 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.018
divalent metal ion transport GO:0070838 172 0.018
response to oxidative stress GO:0006979 123 0.018
anatomical structure homeostasis GO:0060249 145 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
multicellular organismal signaling GO:0035637 91 0.018
epithelial cell migration GO:0010631 63 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
oocyte construction GO:0007308 2 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
transmission of nerve impulse GO:0019226 76 0.018
apoptotic signaling pathway GO:0097190 306 0.018
gtp catabolic process GO:0006184 143 0.018
cerebellar granule cell precursor tangential migration GO:0021935 1 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
positive regulation of chromatin modification GO:1903310 28 0.018
negative regulation of molecular function GO:0044092 258 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
protein localization to membrane GO:0072657 108 0.017
regulation of erk1 and erk2 cascade GO:0070372 71 0.017
lateral inhibition GO:0046331 1 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
negative regulation of cell development GO:0010721 169 0.017
mammary gland lobule development GO:0061377 22 0.017
regulation of protein maturation GO:1903317 96 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.017
negative regulation of proteolysis GO:0045861 74 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
respiratory tube development GO:0030323 167 0.017
protein localization to plasma membrane GO:0072659 57 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
cardiac muscle contraction GO:0060048 32 0.016
heart process GO:0003015 94 0.016
cell chemotaxis GO:0060326 81 0.016
metal ion homeostasis GO:0055065 189 0.016
myeloid cell differentiation GO:0030099 233 0.016
developmental maturation GO:0021700 193 0.016
organophosphate catabolic process GO:0046434 232 0.016
cell adhesion GO:0007155 329 0.016
leukocyte chemotaxis GO:0030595 69 0.016
negative regulation of neuron death GO:1901215 98 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
regulation of defense response GO:0031347 233 0.016
cell matrix adhesion GO:0007160 68 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
insulin secretion GO:0030073 89 0.016
regulation of chromosome organization GO:0033044 83 0.016
negative regulation of protein processing GO:0010955 79 0.016
purine containing compound metabolic process GO:0072521 311 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
glycoprotein metabolic process GO:0009100 116 0.016
nucleotide catabolic process GO:0009166 217 0.016
inflammatory response GO:0006954 244 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of transporter activity GO:0032409 57 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
cellular response to cytokine stimulus GO:0071345 189 0.015
regulation of toll signaling pathway GO:0008592 1 0.015
response to nutrient levels GO:0031667 109 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
negative regulation of cell motility GO:2000146 61 0.015
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
antigen receptor mediated signaling pathway GO:0050851 64 0.015
epithelium migration GO:0090132 63 0.015
regulation of cell size GO:0008361 72 0.015
positive regulation of transferase activity GO:0051347 167 0.015
hormone secretion GO:0046879 128 0.015
regulation of neuron projection development GO:0010975 169 0.014
connective tissue development GO:0061448 179 0.014
response to reactive oxygen species GO:0000302 56 0.014
protein autophosphorylation GO:0046777 61 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
cellular response to lipid GO:0071396 145 0.014
response to transforming growth factor beta GO:0071559 88 0.014
detection of stimulus GO:0051606 84 0.014
positive regulation of secretion GO:0051047 130 0.014
lysosome organization GO:0007040 21 0.014
negative regulation of secretion by cell GO:1903531 54 0.014
tissue remodeling GO:0048771 102 0.014
leukocyte differentiation GO:0002521 342 0.014
phospholipid metabolic process GO:0006644 87 0.014
regulation of cell adhesion GO:0030155 154 0.014
tissue migration GO:0090130 68 0.014
sympathetic neuron projection guidance GO:0097491 4 0.014
regulation of mapk cascade GO:0043408 248 0.014
divalent inorganic cation transport GO:0072511 178 0.014
response to oxygen levels GO:0070482 62 0.014
positive regulation of kinase activity GO:0033674 155 0.014
stem cell differentiation GO:0048863 268 0.014
synaptic transmission GO:0007268 329 0.014
negative regulation of cell projection organization GO:0031345 56 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
adherens junction maintenance GO:0034334 1 0.014
sequestering of metal ion GO:0051238 19 0.013
regulation of proteolysis GO:0030162 164 0.013
fertilization GO:0009566 127 0.013
early endosome to late endosome transport GO:0045022 2 0.013
positive regulation of gene silencing by mirna GO:2000637 1 0.013
b cell activation GO:0042113 161 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
activation of innate immune response GO:0002218 56 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
nuclear transport GO:0051169 139 0.013
negative regulation of homeostatic process GO:0032845 71 0.013
positive regulation of intracellular transport GO:0032388 70 0.013
tissue homeostasis GO:0001894 115 0.013
synapse organization GO:0050808 125 0.013
regulation of homeostatic process GO:0032844 182 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
response to organonitrogen compound GO:0010243 246 0.013
regulation of cytokine production GO:0001817 266 0.013
semaphorin plexin signaling pathway GO:0071526 21 0.013
maintenance of location GO:0051235 89 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
neuronal action potential GO:0019228 54 0.013
blood vessel morphogenesis GO:0048514 285 0.013
granulocyte migration GO:0097530 43 0.012
camera type eye development GO:0043010 266 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
wound healing GO:0042060 157 0.012
germ cell development GO:0007281 185 0.012
cell maturation GO:0048469 127 0.012
positive regulation of notch signaling pathway GO:0045747 18 0.012
histone modification GO:0016570 159 0.012
protein localization to organelle GO:0033365 185 0.012
protein targeting GO:0006605 143 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
regulation of cytoplasmic translation GO:2000765 4 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
cell fate commitment GO:0045165 210 0.012
regulation of hormone secretion GO:0046883 88 0.012
neuron apoptotic process GO:0051402 142 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
chemotaxis GO:0006935 247 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
positive regulation of organelle organization GO:0010638 128 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
digestive tract development GO:0048565 190 0.011
dna metabolic process GO:0006259 303 0.011
monocarboxylic acid transport GO:0015718 44 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of blood circulation GO:1903522 93 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of innate immune response GO:0045088 91 0.011
regulation of chemotaxis GO:0050920 53 0.011
negative regulation of endopeptidase activity GO:0010951 44 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
carbohydrate catabolic process GO:0016052 32 0.011
regulation of cell activation GO:0050865 289 0.011
defecation GO:0030421 1 0.011
lipid transport GO:0006869 98 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
protein oligomerization GO:0051259 67 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.011
negative regulation of nervous system development GO:0051961 156 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
cellular response to peptide GO:1901653 92 0.011
regulation of endocytosis GO:0030100 69 0.011
regulation of angiogenesis GO:0045765 81 0.011
negative regulation of cell growth GO:0030308 44 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
regulation of transferase activity GO:0051338 263 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
cell cell adhesion GO:0098609 41 0.011
thymocyte migration GO:0072679 2 0.011
regulation of peptidase activity GO:0052547 96 0.011
axon guidance GO:0007411 141 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.011
leukocyte proliferation GO:0070661 172 0.011
striated muscle tissue development GO:0014706 293 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
regulation of striated muscle contraction GO:0006942 25 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
regulation of anatomical structure size GO:0090066 178 0.010
lipid biosynthetic process GO:0008610 179 0.010
regulation of hormone levels GO:0010817 211 0.010
cell cell junction organization GO:0045216 72 0.010
antimicrobial peptide production GO:0002775 2 0.010
membrane depolarization GO:0051899 64 0.010
learning GO:0007612 98 0.010
guanosine containing compound catabolic process GO:1901069 144 0.010
positive regulation of defense response GO:0031349 124 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
organelle localization GO:0051640 179 0.010
proton transport GO:0015992 35 0.010
lipid homeostasis GO:0055088 63 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
cholesterol metabolic process GO:0008203 56 0.010
negative regulation of defense response GO:0031348 77 0.010
pattern recognition receptor signaling pathway GO:0002221 47 0.010
sterol metabolic process GO:0016125 58 0.010
lymphocyte differentiation GO:0030098 242 0.010
positive regulation of growth GO:0045927 104 0.010
positive regulation of cell death GO:0010942 224 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
peptidyl serine modification GO:0018209 83 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.010
regulation of response to wounding GO:1903034 189 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
bone remodeling GO:0046849 53 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
synapse assembly GO:0007416 56 0.010

Igsf8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.033
disease of anatomical entity DOID:7 0 0.033
central nervous system disease DOID:331 0 0.032
neurodegenerative disease DOID:1289 0 0.032
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.011