|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.804
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.745
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.683
|
|
|
|
histone h3 deacetylation
|
GO:0070932 |
8 |
0.683
|
|
|
|
negative regulation of fat cell proliferation
|
GO:0070345 |
2 |
0.636
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.602
|
|
|
|
l glutamate uptake involved in synaptic transmission
|
GO:0051935 |
3 |
0.569
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
5 |
0.562
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.490
|
|
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.467
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.460
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.456
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.442
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.442
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.427
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.415
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.406
|
|
|
|
fat cell proliferation
|
GO:0070341 |
4 |
0.399
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.383
|
Fly |
|
|
lactate biosynthetic process
|
GO:0019249 |
4 |
0.376
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.373
|
|
|
|
regulation of cell cycle checkpoint
|
GO:1901976 |
9 |
0.369
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.356
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.355
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.354
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.346
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.339
|
|
|
|
amino acid uptake involved in synaptic transmission
|
GO:0051933 |
3 |
0.335
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.320
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.316
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.312
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.307
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.307
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.300
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.298
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.289
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.285
|
|
|
|
circadian regulation of translation
|
GO:0097167 |
3 |
0.283
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.279
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.272
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.271
|
|
|
|
negative regulation of circadian rhythm
|
GO:0042754 |
8 |
0.255
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.242
|
|
|
|
locomotor rhythm
|
GO:0045475 |
8 |
0.234
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.233
|
Fly |
|
|
regulation of dna damage checkpoint
|
GO:2000001 |
3 |
0.230
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.230
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.229
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.228
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.228
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.226
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.226
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.223
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.219
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.218
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.215
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.214
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.211
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.211
|
|
|
|
negative regulation of dna templated transcription termination
|
GO:0060567 |
1 |
0.208
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.206
|
Yeast |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.200
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.195
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.195
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.185
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.184
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.183
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.180
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.178
|
Yeast |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.178
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.176
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.174
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.173
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.173
|
|
|
|
amino acid import into cell
|
GO:1902837 |
4 |
0.172
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.169
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.166
|
Yeast |
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.165
|
|
|
|
circadian behavior
|
GO:0048512 |
13 |
0.165
|
Fly |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.164
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.163
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.160
|
Yeast |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.160
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.159
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.159
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.157
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.155
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.155
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.152
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.152
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.148
|
|
|
|
dna templated transcription termination
|
GO:0006353 |
4 |
0.148
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.147
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
10 |
0.146
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.144
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.141
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.141
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.140
|
|
|
|
regulation of fat cell proliferation
|
GO:0070344 |
4 |
0.138
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.137
|
Yeast |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.137
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.137
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.137
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.136
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.135
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.134
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.134
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.134
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.131
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.130
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.130
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.130
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.129
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.128
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.128
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.128
|
|
|
|
cytokine production involved in inflammatory response
|
GO:0002534 |
9 |
0.126
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.125
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.124
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.123
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.123
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.123
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.123
|
Fly |
|
|
protein acylation
|
GO:0043543 |
64 |
0.122
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.117
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.116
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.116
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.115
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.114
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.113
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.112
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.112
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.111
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.111
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.110
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.109
|
|
|
|
protein deacylation
|
GO:0035601 |
36 |
0.108
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.107
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.106
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.104
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.100
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.100
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.099
|
Yeast |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.098
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.097
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.096
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.095
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.095
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.093
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.093
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.092
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.091
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.091
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.091
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.090
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.090
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.089
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.089
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.089
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.089
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.089
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.089
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.088
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.088
|
|
|
|
white fat cell differentiation
|
GO:0050872 |
15 |
0.088
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.087
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.087
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.086
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.085
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.085
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.083
|
Yeast |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.083
|
Fly |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.082
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.082
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.082
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.081
|
|
|
|
regulation of p38mapk cascade
|
GO:1900744 |
3 |
0.081
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.081
|
Fly |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.081
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.080
|
|
|
|
male meiosis i
|
GO:0007141 |
16 |
0.080
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.079
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.079
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.077
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.076
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.076
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.076
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.075
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.075
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.074
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.074
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.074
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.073
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.073
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.073
|
|
|
|
stem cell fate specification
|
GO:0048866 |
3 |
0.073
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.072
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.072
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.072
|
Fly |
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
18 |
0.072
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.072
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
4 |
0.071
|
|
|
|
cardiac cell fate specification
|
GO:0060912 |
2 |
0.071
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.071
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.071
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.071
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.071
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.071
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.071
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.071
|
Fly |
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.070
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.070
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.069
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.069
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.069
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.069
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.068
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.068
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.067
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.067
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.067
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.066
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.066
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.066
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.066
|
Yeast |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.065
|
Fly |
|
|
import into cell
|
GO:0098657 |
8 |
0.065
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.065
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.065
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.064
|
|
|
|
clara cell differentiation
|
GO:0060486 |
4 |
0.064
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.063
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.063
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.063
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.062
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.062
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.062
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.061
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.060
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.060
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.060
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.060
|
Fly |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.060
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.060
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.059
|
Fly |
|
|
stem cell development
|
GO:0048864 |
219 |
0.059
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.058
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
25 |
0.058
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.058
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.057
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.057
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.057
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
31 |
0.057
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.057
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.057
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.057
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.057
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.057
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.056
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.056
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.056
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.056
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.055
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.055
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.055
|
|
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.055
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.054
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.054
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.054
|
Yeast |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.054
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.053
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.053
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.053
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.053
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.053
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.053
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.052
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.052
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.052
|
|
|
|
response to ischemia
|
GO:0002931 |
14 |
0.052
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.052
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.052
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.051
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.051
|
|
|
|
regulation of amino acid import
|
GO:0010958 |
1 |
0.051
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.051
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.051
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.051
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.051
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.051
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.050
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.050
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.050
|
|
|
|
regulation of hair cycle
|
GO:0042634 |
11 |
0.049
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.049
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.049
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.049
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.048
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.048
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.048
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.048
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.046
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
20 |
0.046
|
|
|
|
gonad morphogenesis
|
GO:0035262 |
1 |
0.046
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.046
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.046
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.046
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.046
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.046
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.046
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.045
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.045
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.045
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.045
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.045
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.045
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.045
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.045
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.045
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.045
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.045
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.045
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.044
|
Yeast |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.044
|
|
|
|
neuroblast fate commitment
|
GO:0014017 |
1 |
0.044
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.044
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.044
|
|
|
|
sleep
|
GO:0030431 |
7 |
0.044
|
|
|
|
regulation of cytokine production involved in inflammatory response
|
GO:1900015 |
7 |
0.043
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.043
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.043
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
20 |
0.043
|
|
|
|
heart field specification
|
GO:0003128 |
6 |
0.042
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.042
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.042
|
|
|
|
gluconeogenesis
|
GO:0006094 |
39 |
0.042
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.042
|
|
|
|
schwann cell proliferation
|
GO:0014010 |
2 |
0.041
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.041
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.041
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
4 |
0.041
|
Yeast |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.040
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.040
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.040
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.040
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.040
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.040
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.040
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.040
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.040
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.039
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.039
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.039
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.039
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.039
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.039
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.039
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.038
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.038
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.038
|
Fly |
|
|
connective tissue development
|
GO:0061448 |
179 |
0.038
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.038
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.038
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.038
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.038
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.038
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.038
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.038
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.038
|
|
|
|
glucan biosynthetic process
|
GO:0009250 |
14 |
0.037
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.037
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.037
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.037
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.037
|
Yeast |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.037
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.037
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.037
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.037
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.037
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.037
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.037
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.037
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.037
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.036
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.036
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.036
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.036
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.036
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.036
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
33 |
0.036
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.036
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.036
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.035
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.035
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.035
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.035
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.035
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.035
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.035
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.035
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.034
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.034
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.034
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.034
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.034
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.034
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.034
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.033
|
Yeast |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.033
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.033
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.033
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.033
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.033
|
|
|
|
lung epithelium development
|
GO:0060428 |
37 |
0.033
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.033
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.033
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.033
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.033
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.032
|
Fly |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.032
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.032
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.032
|
|
|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
0.032
|
|
|
|
regulation of dna templated transcription termination
|
GO:0031554 |
1 |
0.032
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.032
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.031
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.031
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.031
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.031
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.031
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.031
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.031
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.031
|
|
|
|
l glutamate transport
|
GO:0015813 |
16 |
0.031
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.031
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.031
|
Yeast |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.031
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.030
|
Worm |
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.030
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.030
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.030
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.030
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.030
|
|
|
|
learning
|
GO:0007612 |
98 |
0.030
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.030
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.030
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.030
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.030
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.030
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.030
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.030
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.030
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.030
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.030
|
Yeast |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.030
|
|
|
|
neurotransmitter uptake
|
GO:0001504 |
14 |
0.029
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.029
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.029
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.029
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.029
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.029
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.029
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.029
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.029
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.029
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.029
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.029
|
|
|
|
rhythmic behavior
|
GO:0007622 |
15 |
0.029
|
Fly |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.029
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.029
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.028
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.028
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.028
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.028
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.028
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.028
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.028
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.028
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.028
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.028
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.028
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.028
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.028
|
|
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
11 |
0.027
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.027
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
29 |
0.027
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.027
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.027
|
|
|
|
positive regulation of striated muscle tissue development
|
GO:0045844 |
31 |
0.027
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.027
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.027
|
Fly |
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
19 |
0.027
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.027
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.027
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.027
|
|
