Mus musculus

34 known processes

Gbp1

guanylate binding protein 1

(Aliases: Gbp-1,5830475C06,Mag-1,MGC124334,Mpa-1,Mpa1)

Gbp1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.951
regulation of defense response GO:0031347 233 0.591
innate immune response GO:0045087 157 0.536
immune effector process GO:0002252 321 0.424
cellular response to biotic stimulus GO:0071216 92 0.416
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.394
cytokine mediated signaling pathway GO:0019221 115 0.377
cellular response to lipopolysaccharide GO:0071222 77 0.333
Mouse
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.329
defense response to gram positive bacterium GO:0050830 50 0.292
negative regulation of immune system process GO:0002683 209 0.235
leukocyte mediated immunity GO:0002443 174 0.225
cell killing GO:0001906 67 0.223
regulation of innate immune response GO:0045088 91 0.212
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.209
adaptive immune response GO:0002250 155 0.208
cytokine production GO:0001816 319 0.189
activation of immune response GO:0002253 138 0.185
inflammatory response GO:0006954 244 0.177
activation of innate immune response GO:0002218 56 0.168
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.158
myeloid leukocyte differentiation GO:0002573 119 0.154
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.144
leukocyte mediated cytotoxicity GO:0001909 62 0.142
purine ribonucleotide metabolic process GO:0009150 290 0.140
nucleotide metabolic process GO:0009117 332 0.137
negative regulation of molecular function GO:0044092 258 0.131
cellular response to molecule of bacterial origin GO:0071219 83 0.129
Mouse
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.127
negative regulation of protein metabolic process GO:0051248 282 0.126
regulation of reactive oxygen species metabolic process GO:2000377 40 0.123
response to molecule of bacterial origin GO:0002237 143 0.123
Mouse
growth of symbiont in host GO:0044117 23 0.122
killing of cells of other organism GO:0031640 13 0.121
positive regulation of cytokine production GO:0001819 174 0.119
regulation of homeostatic process GO:0032844 182 0.118
cellular response to interferon beta GO:0035458 21 0.118
aromatic compound catabolic process GO:0019439 286 0.118
positive regulation of leukocyte mediated immunity GO:0002705 70 0.117
cellular homeostasis GO:0019725 240 0.116
defense response to bacterium GO:0042742 119 0.115
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.110
regulation of cell activation GO:0050865 289 0.108
disruption by host of symbiont cells GO:0051852 11 0.108
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.107
purine nucleotide metabolic process GO:0006163 302 0.107
positive regulation of defense response GO:0031349 124 0.106
leukocyte differentiation GO:0002521 342 0.104
pattern recognition receptor signaling pathway GO:0002221 47 0.103
lymphocyte mediated immunity GO:0002449 139 0.103
ribonucleotide metabolic process GO:0009259 291 0.102
interferon gamma production GO:0032609 67 0.102
cellular response to lipid GO:0071396 145 0.101
Mouse
killing by host of symbiont cells GO:0051873 11 0.097
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.097
regulation of protein localization GO:0032880 231 0.096
apoptotic signaling pathway GO:0097190 306 0.095
positive regulation of immune effector process GO:0002699 107 0.095
response to molecule of fungal origin GO:0002238 4 0.093
nucleoside phosphate metabolic process GO:0006753 338 0.089
regulation of interferon gamma production GO:0032649 57 0.088
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.087
regulation of cytokine production GO:0001817 266 0.086
regulation of growth of symbiont in host GO:0044126 19 0.085
carbohydrate metabolic process GO:0005975 230 0.085
organic cyclic compound catabolic process GO:1901361 295 0.084
interspecies interaction between organisms GO:0044419 83 0.084
positive regulation of interferon gamma production GO:0032729 39 0.084
myeloid leukocyte mediated immunity GO:0002444 42 0.084
regulation of hydrolase activity GO:0051336 246 0.083
regulation of cytokine biosynthetic process GO:0042035 59 0.083
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.083
regulation of leukocyte proliferation GO:0070663 121 0.082
immune response regulating signaling pathway GO:0002764 125 0.081
mapk cascade GO:0000165 281 0.080
negative regulation of growth of symbiont in host GO:0044130 19 0.079
regulation of establishment of protein localization GO:0070201 181 0.079
chemotaxis GO:0006935 247 0.079
cell activation involved in immune response GO:0002263 126 0.079
myeloid cell differentiation GO:0030099 233 0.079
extrinsic apoptotic signaling pathway GO:0097191 126 0.078
negative regulation of cytokine production GO:0001818 84 0.077
negative regulation of phosphate metabolic process GO:0045936 184 0.076
negative regulation of hydrolase activity GO:0051346 71 0.076
regulation of cytokine secretion GO:0050707 61 0.076
growth involved in symbiotic interaction GO:0044110 23 0.076
nucleobase containing small molecule metabolic process GO:0055086 352 0.076
negative regulation of phosphorus metabolic process GO:0010563 184 0.074
positive regulation of t cell activation GO:0050870 101 0.073
t cell differentiation GO:0030217 174 0.073
nucleoside phosphate catabolic process GO:1901292 222 0.073
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.072
regulation of hormone levels GO:0010817 211 0.072
acute inflammatory response GO:0002526 41 0.071
response to interferon gamma GO:0034341 34 0.071
lymphocyte differentiation GO:0030098 242 0.070
regulation of leukocyte mediated immunity GO:0002703 104 0.070
dna metabolic process GO:0006259 303 0.069
protein secretion GO:0009306 111 0.069
angiogenesis GO:0001525 201 0.069
negative regulation of cell proliferation GO:0008285 296 0.068
immune response activating signal transduction GO:0002757 116 0.067
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.066
calcium ion homeostasis GO:0055074 127 0.066
t cell proliferation GO:0042098 120 0.066
response to lipopolysaccharide GO:0032496 128 0.066
Mouse
cytokine metabolic process GO:0042107 71 0.065
detection of yeast GO:0001879 2 0.065
regulation of protein transport GO:0051223 163 0.065
cellular amino acid metabolic process GO:0006520 103 0.065
positive regulation of cell development GO:0010720 237 0.064
positive regulation of lymphocyte activation GO:0051251 140 0.064
cellular amine metabolic process GO:0044106 44 0.064
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.064
nucleotide catabolic process GO:0009166 217 0.063
purine containing compound metabolic process GO:0072521 311 0.063
disruption of cells of other organism GO:0044364 13 0.063
mature dendritic cell differentiation GO:0097029 3 0.063
divalent inorganic cation homeostasis GO:0072507 138 0.062
skeletal muscle fiber development GO:0048741 58 0.062
lymphocyte proliferation GO:0046651 164 0.061
regulation of secretion GO:0051046 274 0.061
cell recognition GO:0008037 83 0.061
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.061
heterocycle catabolic process GO:0046700 280 0.060
regulation of angiotensin levels in blood GO:0002002 4 0.060
regulation of inflammatory response GO:0050727 147 0.060
cation homeostasis GO:0055080 212 0.060
reactive oxygen species metabolic process GO:0072593 84 0.059
regulation of angiotensin metabolic process GO:0060177 4 0.058
gland development GO:0048732 330 0.058
phagocytosis GO:0006909 66 0.057
leukocyte proliferation GO:0070661 172 0.057
oxidation reduction process GO:0055114 342 0.056
regulation of multi organism process GO:0043900 111 0.056
regulation of lymphocyte proliferation GO:0050670 117 0.055
regulation of secretion by cell GO:1903530 249 0.055
regulation of angiogenesis GO:0045765 81 0.055
g protein coupled receptor signaling pathway GO:0007186 243 0.054
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.054
epithelial tube morphogenesis GO:0060562 303 0.053
positive regulation of cell activation GO:0050867 158 0.053
organic hydroxy compound metabolic process GO:1901615 203 0.053
carbohydrate derivative catabolic process GO:1901136 231 0.053
regulation of intracellular transport GO:0032386 159 0.052
morphogenesis of a branching structure GO:0001763 203 0.052
positive regulation of leukocyte differentiation GO:1902107 86 0.052
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
positive regulation of t cell costimulation GO:2000525 2 0.051
detection of fungus GO:0016046 2 0.051
cytokine biosynthetic process GO:0042089 68 0.051
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.050
negative regulation of macrophage apoptotic process GO:2000110 3 0.050
cytokine secretion GO:0050663 72 0.049
antigen processing and presentation GO:0019882 47 0.049
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.048
growth of symbiont involved in interaction with host GO:0044116 23 0.048
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.048
regulation of cytoplasmic transport GO:1903649 112 0.048
carbohydrate derivative biosynthetic process GO:1901137 183 0.048
regulation of cell killing GO:0031341 40 0.046
forebrain development GO:0030900 302 0.046
regulation of protein secretion GO:0050708 82 0.046
positive regulation of innate immune response GO:0045089 80 0.046
glycoprotein biosynthetic process GO:0009101 89 0.045
regulation of proteolysis GO:0030162 164 0.045
leukocyte activation involved in immune response GO:0002366 126 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
sequestering of calcium ion GO:0051208 18 0.045
natural killer cell activation GO:0030101 44 0.045
regulation of interleukin 2 production GO:0032663 28 0.045
rho protein signal transduction GO:0007266 32 0.044
alpha beta t cell activation GO:0046631 91 0.044
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.044
regulation of stress activated mapk cascade GO:0032872 69 0.044
regulation of cell migration GO:0030334 219 0.044
positive regulation of cytokine biosynthetic process GO:0042108 40 0.043
organonitrogen compound catabolic process GO:1901565 264 0.043
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.042
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.042
innate immune response activating signal transduction GO:0002758 50 0.041
regulation of cell motility GO:2000145 236 0.041
regulation of apoptotic signaling pathway GO:2001233 197 0.041
organophosphate catabolic process GO:0046434 232 0.041
dna recombination GO:0006310 92 0.040
cellular response to molecule of fungal origin GO:0071226 2 0.040
regulation of leukocyte differentiation GO:1902105 159 0.040
regulation of protein complex assembly GO:0043254 83 0.039
endocytosis GO:0006897 168 0.039
regulation of lymphocyte mediated immunity GO:0002706 84 0.039
negative regulation of phosphorylation GO:0042326 166 0.039
amine metabolic process GO:0009308 45 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.039
metal ion homeostasis GO:0055065 189 0.039
ribonucleoside catabolic process GO:0042454 206 0.039
interaction with symbiont GO:0051702 14 0.039
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.039
regulation of lymphocyte activation GO:0051249 240 0.039
b cell mediated immunity GO:0019724 71 0.039
blood vessel morphogenesis GO:0048514 285 0.038
positive regulation of secretion GO:0051047 130 0.038
regulation of mapk cascade GO:0043408 248 0.038
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.037
glycoprotein metabolic process GO:0009100 116 0.037
myotube differentiation GO:0014902 105 0.037
positive regulation of programmed cell death GO:0043068 218 0.036
nucleoside metabolic process GO:0009116 246 0.036
leukocyte apoptotic process GO:0071887 71 0.036
skin development GO:0043588 220 0.036
i kappab kinase nf kappab signaling GO:0007249 85 0.036
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.035
striated muscle tissue development GO:0014706 293 0.035
regulation of response to biotic stimulus GO:0002831 38 0.035
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.035
placenta development GO:0001890 140 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.034
single organismal cell cell adhesion GO:0016337 131 0.034
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.034
positive regulation of camp mediated signaling GO:0043950 3 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
sequestering of metal ion GO:0051238 19 0.034
purine nucleoside catabolic process GO:0006152 205 0.033
protein import into nucleus GO:0006606 95 0.033
positive regulation of lymphocyte proliferation GO:0050671 70 0.033
positive regulation of intracellular transport GO:0032388 70 0.033
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.033
regulation of natural killer cell mediated immunity GO:0002715 19 0.033
peptidyl tyrosine modification GO:0018212 145 0.033
immunoglobulin production GO:0002377 73 0.033
negative regulation of multi organism process GO:0043901 68 0.032
purine containing compound catabolic process GO:0072523 213 0.032
regulation of myoblast differentiation GO:0045661 29 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
t cell receptor signaling pathway GO:0050852 46 0.031
regulation of monocyte chemotaxis GO:0090025 3 0.031
negative regulation of eosinophil degranulation GO:0043310 1 0.031
negative regulation of defense response GO:0031348 77 0.031
neutrophil mediated killing of bacterium GO:0070944 6 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
negative regulation of myoblast differentiation GO:0045662 18 0.031
epithelial cell proliferation GO:0050673 174 0.031
positive regulation of response to wounding GO:1903036 66 0.030
stress activated mapk cascade GO:0051403 80 0.030
muscle tissue development GO:0060537 308 0.030
regulation of intracellular protein transport GO:0033157 82 0.030
regulation of vasculature development GO:1901342 88 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
antigen processing and presentation of exogenous antigen GO:0019884 26 0.029
detection of stimulus GO:0051606 84 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
eosinophil activation involved in immune response GO:0002278 1 0.029
regulation of b cell activation GO:0050864 81 0.029
immunoglobulin mediated immune response GO:0016064 69 0.029
modification of morphology or physiology of other organism GO:0035821 18 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.029
detection of other organism GO:0098543 8 0.029
defense response to virus GO:0051607 68 0.029
cellular response to dna damage stimulus GO:0006974 207 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
regulation of acute inflammatory response GO:0002673 27 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
regulation of adaptive immune response GO:0002819 90 0.028
chemokine mediated signaling pathway GO:0070098 17 0.028
protein maturation GO:0051604 176 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
interleukin 2 production GO:0032623 33 0.028
positive regulation of adaptive immune response GO:0002821 61 0.027
cellular ketone metabolic process GO:0042180 84 0.027
peptide transport GO:0015833 133 0.027
regulation of map kinase activity GO:0043405 120 0.027
midgut development GO:0007494 4 0.027
myoblast differentiation GO:0045445 52 0.027
jnk cascade GO:0007254 72 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.027
regulation of vesicle mediated transport GO:0060627 139 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
negative regulation of protein modification process GO:0031400 163 0.026
neutrophil migration GO:1990266 37 0.026
regulation of protein import into nucleus GO:0042306 52 0.026
sensory perception GO:0007600 245 0.025
regulation of t cell proliferation GO:0042129 92 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
intracellular protein transport GO:0006886 204 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.025
positive regulation of immunological synapse formation GO:2000522 1 0.025
interleukin 2 biosynthetic process GO:0042094 15 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
tumor necrosis factor production GO:0032640 50 0.025
negative regulation of nervous system development GO:0051961 156 0.025
regulation of skeletal muscle fiber development GO:0048742 36 0.025
leukocyte migration GO:0050900 124 0.024
membrane organization GO:0061024 245 0.024
positive regulation of nervous system development GO:0051962 221 0.024
camp metabolic process GO:0046058 40 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
positive regulation of organelle organization GO:0010638 128 0.024
regulation of organelle organization GO:0033043 289 0.024
regulation of chemotaxis GO:0050920 53 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
regulation of t cell activation GO:0050863 170 0.024
regulation of immunoglobulin mediated immune response GO:0002889 37 0.024
tissue remodeling GO:0048771 102 0.024
positive regulation of interferon alpha production GO:0032727 4 0.024
protein localization to nucleus GO:0034504 121 0.024
regulation of cell cycle process GO:0010564 160 0.024
regulation of response to wounding GO:1903034 189 0.024
regulation of jnk cascade GO:0046328 62 0.024
ribonucleoside metabolic process GO:0009119 245 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
positive regulation of cell motility GO:2000147 116 0.023
myeloid leukocyte activation GO:0002274 83 0.023
carbohydrate transport GO:0008643 62 0.023
cell type specific apoptotic process GO:0097285 268 0.023
natural killer cell mediated cytotoxicity GO:0042267 29 0.023
regulation of immunoglobulin production GO:0002637 42 0.023
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
positive regulation of map kinase activity GO:0043406 84 0.023
granulocyte chemotaxis GO:0071621 39 0.023
homeostasis of number of cells GO:0048872 210 0.023
protein ubiquitination GO:0016567 171 0.023
t cell differentiation involved in immune response GO:0002292 30 0.023
eosinophil mediated immunity GO:0002447 1 0.023
small gtpase mediated signal transduction GO:0007264 97 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
pyridine containing compound catabolic process GO:0072526 4 0.022
reactive oxygen species biosynthetic process GO:1903409 8 0.022
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.022
regulation of peptidase activity GO:0052547 96 0.022
regulation of humoral immune response GO:0002920 22 0.022
positive regulation of jun kinase activity GO:0043507 30 0.022
positive regulation of leukocyte proliferation GO:0070665 73 0.022
telencephalon development GO:0021537 186 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
neutrophil mediated cytotoxicity GO:0070942 8 0.022
guanosine containing compound catabolic process GO:1901069 144 0.022
positive regulation of cell death GO:0010942 224 0.022
regulation of nucleocytoplasmic transport GO:0046822 73 0.022
necrotic cell death GO:0070265 30 0.022
protein localization to organelle GO:0033365 185 0.022
necroptotic process GO:0070266 21 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
regulation of leukocyte apoptotic process GO:2000106 56 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.021
defense response to gram negative bacterium GO:0050829 28 0.021
muscle cell development GO:0055001 133 0.021
chemokine production GO:0032602 34 0.021
regulation of protein kinase activity GO:0045859 232 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
peptidyl amino acid modification GO:0018193 336 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
b cell activation GO:0042113 161 0.021
alpha beta t cell activation involved in immune response GO:0002287 31 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
nucleoside catabolic process GO:0009164 206 0.021
cation transport GO:0006812 399 0.020
regulation of muscle tissue development GO:1901861 97 0.020
regulation of endopeptidase activity GO:0052548 89 0.020
leukocyte chemotaxis GO:0030595 69 0.020
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.020
syncytium formation by plasma membrane fusion GO:0000768 42 0.020
muscle cell differentiation GO:0042692 261 0.020
positive regulation of chemotaxis GO:0050921 38 0.020
regulation of striated muscle cell differentiation GO:0051153 81 0.020
regulation of kinase activity GO:0043549 249 0.020
regulation of dendritic cell chemotaxis GO:2000508 1 0.020
nitrogen compound transport GO:0071705 271 0.020
positive regulation of homeostatic process GO:0032846 64 0.020
maintenance of location GO:0051235 89 0.020
positive regulation of b cell mediated immunity GO:0002714 26 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
regulation of peptide transport GO:0090087 91 0.019
developmental maturation GO:0021700 193 0.019
cell chemotaxis GO:0060326 81 0.019
actin polymerization or depolymerization GO:0008154 54 0.019
glucose homeostasis GO:0042593 128 0.019
monosaccharide transport GO:0015749 58 0.019
positive regulation of jnk cascade GO:0046330 46 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
regulation of protein localization to nucleus GO:1900180 60 0.019
regulation of cellular response to stress GO:0080135 159 0.019
isotype switching GO:0045190 36 0.019
programmed necrotic cell death GO:0097300 28 0.019
intracellular receptor signaling pathway GO:0030522 74 0.019
microglial cell activation involved in immune response GO:0002282 1 0.019
positive regulation of acute inflammatory response GO:0002675 16 0.019
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.019
positive regulation of cell killing GO:0031343 33 0.019
regulation of systemic arterial blood pressure GO:0003073 61 0.019
regulation of neuron differentiation GO:0045664 281 0.019
regulation of cell cycle GO:0051726 281 0.019
ras protein signal transduction GO:0007265 77 0.019
cytosolic calcium ion homeostasis GO:0051480 70 0.019
positive regulation of inflammatory response GO:0050729 47 0.019
regulation of phagocytosis GO:0050764 33 0.019
negative regulation of cell activation GO:0050866 111 0.019
regulation of protein processing GO:0070613 96 0.019
negative regulation of lymphocyte proliferation GO:0050672 45 0.019
regulation of type i interferon production GO:0032479 22 0.019
positive regulation of alpha beta t cell activation GO:0046635 39 0.019
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.019
negative regulation of regulatory t cell differentiation GO:0045590 2 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
regulation of interleukin 12 production GO:0032655 30 0.018
regulation of protein targeting GO:1903533 61 0.018
regulation of tumor necrosis factor production GO:0032680 49 0.018
modification by host of symbiont morphology or physiology GO:0051851 12 0.018
protein processing GO:0016485 163 0.018
regulation of body fluid levels GO:0050878 162 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
granulocyte migration GO:0097530 43 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
dephosphorylation GO:0016311 129 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regulation of glial cell differentiation GO:0045685 41 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
peptide hormone secretion GO:0030072 109 0.018
negative regulation of response to wounding GO:1903035 77 0.018
positive regulation of behavior GO:0048520 40 0.018
lipid biosynthetic process GO:0008610 179 0.018
regulation of alpha beta t cell proliferation GO:0046640 18 0.018
t helper 17 cell chemotaxis GO:0035705 1 0.018
glucose transport GO:0015758 56 0.018
gtp catabolic process GO:0006184 143 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
skeletal muscle organ development GO:0060538 163 0.018
b cell activation involved in immune response GO:0002312 50 0.018
t helper 1 type immune response GO:0042088 25 0.018
t cell costimulation GO:0031295 14 0.018
protein targeting GO:0006605 143 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
regulation of ossification GO:0030278 112 0.017
t cell selection GO:0045058 34 0.017
positive regulation of endocytosis GO:0045807 42 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
amide transport GO:0042886 138 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.017
organic acid biosynthetic process GO:0016053 86 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
negative regulation of innate immune response GO:0045824 17 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
muscle fiber development GO:0048747 76 0.017
regulation of blood pressure GO:0008217 93 0.017
regulation of protein maturation GO:1903317 96 0.017
nuclear transport GO:0051169 139 0.017
cytoplasmic transport GO:0016482 234 0.017
cellular chemical homeostasis GO:0055082 215 0.017
stress activated protein kinase signaling cascade GO:0031098 81 0.017
syncytium formation GO:0006949 43 0.017
macrophage activation GO:0042116 27 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
extracellular structure organization GO:0043062 148 0.017
axonogenesis GO:0007409 274 0.016
glial cell differentiation GO:0010001 131 0.016
response to organonitrogen compound GO:0010243 246 0.016
response to extracellular stimulus GO:0009991 127 0.016
hematopoietic stem cell proliferation GO:0071425 13 0.016
gtp metabolic process GO:0046039 144 0.016
neutrophil mediated killing of symbiont cell GO:0070943 8 0.016
t cell activation GO:0042110 289 0.016
hexose transport GO:0008645 56 0.016
myeloid dendritic cell differentiation GO:0043011 16 0.016
negative regulation of kinase activity GO:0033673 81 0.016
neutrophil chemotaxis GO:0030593 36 0.016
striated muscle cell development GO:0055002 125 0.016
myotube cell development GO:0014904 60 0.016
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.016
regulation of alpha beta t cell activation GO:0046634 53 0.016
positive regulation of protein localization to nucleus GO:1900182 30 0.016
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.016
antigen receptor mediated signaling pathway GO:0050851 64 0.016
cyclic nucleotide metabolic process GO:0009187 59 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.016
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.016
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.015
positive regulation of monocyte chemotaxis GO:0090026 2 0.015
embryonic organ morphogenesis GO:0048562 276 0.015

Gbp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
musculoskeletal system disease DOID:17 0 0.028
connective tissue disease DOID:65 0 0.028
immune system disease DOID:2914 0 0.020
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.015