Mus musculus

101 known processes

Napa

N-ethylmaleimide sensitive fusion protein attachment protein alpha

(Aliases: RA81,hyh,SNAPA,1500039N14Rik,SNARE,a-SNAP,AW209189)

Napa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle assembly GO:0070925 177 0.156
pigmentation GO:0043473 71 0.114
regulation of cellular amino acid metabolic process GO:0006521 5 0.094
regulation of secretion by cell GO:1903530 249 0.088
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.086
nucleobase containing small molecule metabolic process GO:0055086 352 0.078
positive regulation of necrotic cell death GO:0010940 1 0.076
cellular amine metabolic process GO:0044106 44 0.072
protein modification by small protein conjugation GO:0032446 187 0.068
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.066
heterocycle catabolic process GO:0046700 280 0.063
regulation of cell growth GO:0001558 91 0.063
cellular amino acid metabolic process GO:0006520 103 0.062
cellular component assembly involved in morphogenesis GO:0010927 139 0.061
purine containing compound metabolic process GO:0072521 311 0.061
regulation of cellular amine metabolic process GO:0033238 20 0.059
camera type eye development GO:0043010 266 0.058
nucleoside phosphate metabolic process GO:0006753 338 0.058
cilium morphogenesis GO:0060271 102 0.057
regulation of cell cycle GO:0051726 281 0.057
protein ubiquitination GO:0016567 171 0.056
nucleotide metabolic process GO:0009117 332 0.056
nucleoside monophosphate metabolic process GO:0009123 85 0.054
cellular ketone metabolic process GO:0042180 84 0.054
cation transport GO:0006812 399 0.054
regulation of proteolysis GO:0030162 164 0.052
positive regulation of cell development GO:0010720 237 0.052
nucleotide catabolic process GO:0009166 217 0.052
nucleoside phosphate catabolic process GO:1901292 222 0.051
regulation of organelle organization GO:0033043 289 0.051
purine ribonucleotide catabolic process GO:0009154 208 0.050
modification dependent protein catabolic process GO:0019941 133 0.050
ubiquitin dependent protein catabolic process GO:0006511 129 0.049
amine metabolic process GO:0009308 45 0.049
positive regulation of cellular catabolic process GO:0031331 148 0.049
purine nucleoside catabolic process GO:0006152 205 0.049
axonogenesis GO:0007409 274 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
ribonucleoside monophosphate catabolic process GO:0009158 57 0.047
cellular macromolecule catabolic process GO:0044265 206 0.047
aromatic compound catabolic process GO:0019439 286 0.046
regulation of cellular catabolic process GO:0031329 242 0.046
synaptic transmission GO:0007268 329 0.045
cellular protein catabolic process GO:0044257 155 0.044
regulation of secretion GO:0051046 274 0.044
cilium assembly GO:0042384 81 0.043
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
organophosphate catabolic process GO:0046434 232 0.042
golgi to endosome transport GO:0006895 3 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.041
retina development in camera type eye GO:0060041 119 0.041
autophagy GO:0006914 45 0.041
histone modification GO:0016570 159 0.040
organelle localization GO:0051640 179 0.039
cytoplasmic transport GO:0016482 234 0.038
regulation of cellular component biogenesis GO:0044087 181 0.038
glycosyl compound catabolic process GO:1901658 206 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.038
positive regulation of protein phosphorylation GO:0001934 242 0.038
regulation of vesicle mediated transport GO:0060627 139 0.037
response to organonitrogen compound GO:0010243 246 0.037
endomembrane system organization GO:0010256 147 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
positive regulation of protein modification process GO:0031401 299 0.037
regulation of proteasomal protein catabolic process GO:0061136 46 0.036
developmental maturation GO:0021700 193 0.036
organonitrogen compound catabolic process GO:1901565 264 0.035
inorganic cation transmembrane transport GO:0098662 207 0.035
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.034
transmembrane transport GO:0055085 412 0.034
macroautophagy GO:0016236 21 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.033
cell maturation GO:0048469 127 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
nucleoside metabolic process GO:0009116 246 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
sensory system development GO:0048880 3 0.032
establishment of melanosome localization GO:0032401 11 0.031
nucleoside monophosphate catabolic process GO:0009125 59 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
gene silencing by rna GO:0031047 19 0.030
modification dependent macromolecule catabolic process GO:0043632 133 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
apoptotic signaling pathway GO:0097190 306 0.030
negative regulation of cellular component organization GO:0051129 194 0.030
positive regulation of proteolysis GO:0045862 85 0.029
chromatin organization GO:0006325 206 0.029
negative regulation of cellular amine metabolic process GO:0033239 1 0.029
nitrogen compound transport GO:0071705 271 0.029
regulation of neuron projection development GO:0010975 169 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
regulation of cellular protein catabolic process GO:1903362 61 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
cellular homeostasis GO:0019725 240 0.028
positive regulation of cellular protein catabolic process GO:1903364 34 0.028
cellular response to extracellular stimulus GO:0031668 81 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
establishment of organelle localization GO:0051656 122 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
cation transmembrane transport GO:0098655 266 0.027
retrograde transport endosome to golgi GO:0042147 2 0.027
cellular response to external stimulus GO:0071496 88 0.027
small gtpase mediated signal transduction GO:0007264 97 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
attachment of spindle microtubules to kinetochore GO:0008608 4 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
protein catabolic process GO:0030163 221 0.026
ras protein signal transduction GO:0007265 77 0.026
cation homeostasis GO:0055080 212 0.026
negative regulation of protein modification process GO:0031400 163 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
cellular chemical homeostasis GO:0055082 215 0.026
rab protein signal transduction GO:0032482 1 0.026
lymphocyte differentiation GO:0030098 242 0.025
negative regulation of molecular function GO:0044092 258 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
maintenance of location GO:0051235 89 0.025
nucleoside catabolic process GO:0009164 206 0.025
vesicle localization GO:0051648 86 0.025
ion transmembrane transport GO:0034220 361 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
microtubule based process GO:0007017 236 0.024
negative regulation of nervous system development GO:0051961 156 0.024
dna metabolic process GO:0006259 303 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
peptidyl amino acid modification GO:0018193 336 0.024
intracellular protein transport GO:0006886 204 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
cellular protein complex assembly GO:0043623 116 0.023
vacuole organization GO:0007033 38 0.023
lateral line system development GO:0048925 1 0.023
interspecies interaction between organisms GO:0044419 83 0.023
regulation of binding GO:0051098 111 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
pigment granule transport GO:0051904 12 0.023
spermatogenesis GO:0007283 284 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
response to metal ion GO:0010038 47 0.023
protein localization to membrane GO:0072657 108 0.022
regulation of hormone levels GO:0010817 211 0.022
regulation of protein catabolic process GO:0042176 108 0.022
regulation of protein kinase activity GO:0045859 232 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
metal ion homeostasis GO:0055065 189 0.022
fat cell differentiation GO:0045444 160 0.022
chromatin modification GO:0016568 187 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.022
male gamete generation GO:0048232 285 0.022
vesicle organization GO:0016050 60 0.022
positive regulation of transferase activity GO:0051347 167 0.022
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
cell division GO:0051301 120 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
cell growth GO:0016049 130 0.021
determination of left right symmetry GO:0007368 80 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
substantia nigra development GO:0021762 2 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
muscle tissue development GO:0060537 308 0.020
exocytosis GO:0006887 121 0.020
protein modification by small protein removal GO:0070646 21 0.020
protein localization to plasma membrane GO:0072659 57 0.020
protein localization to organelle GO:0033365 185 0.020
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
plasma membrane organization GO:0007009 90 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
positive regulation of binding GO:0051099 49 0.019
macromolecule catabolic process GO:0009057 281 0.019
covalent chromatin modification GO:0016569 163 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
cellular response to nutrient levels GO:0031669 64 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.018
positive regulation of cell death GO:0010942 224 0.018
peptide transport GO:0015833 133 0.018
telencephalon development GO:0021537 186 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
negative regulation of growth GO:0045926 99 0.018
organelle fission GO:0048285 170 0.018
rna splicing GO:0008380 54 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.017
negative regulation of cell cycle GO:0045786 123 0.017
melanosome transport GO:0032402 11 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
regulation of protein maturation GO:1903317 96 0.017
virion assembly GO:0019068 1 0.017
regulation of anatomical structure size GO:0090066 178 0.017
positive regulation of protein catabolic process GO:0045732 60 0.017
mapk cascade GO:0000165 281 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
hydrogen ion transmembrane transport GO:1902600 25 0.017
regulation of protein localization GO:0032880 231 0.017
regulation of synaptic plasticity GO:0048167 87 0.017
microtubule based movement GO:0007018 84 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
dephosphorylation GO:0016311 129 0.017
embryonic heart tube morphogenesis GO:0003143 51 0.016
striated muscle tissue development GO:0014706 293 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
divalent inorganic cation transport GO:0072511 178 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
protein processing GO:0016485 163 0.016
regulation of multi organism process GO:0043900 111 0.016
sensory organ morphogenesis GO:0090596 242 0.016
blood circulation GO:0008015 195 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
negative regulation of multi organism process GO:0043901 68 0.016
mitotic cell cycle GO:0000278 195 0.016
histone deacetylation GO:0016575 26 0.016
regulation of muscle tissue development GO:1901861 97 0.016
cellular pigmentation GO:0033059 20 0.016
rho protein signal transduction GO:0007266 32 0.016
cerebellum development GO:0021549 77 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
telencephalon cell migration GO:0022029 55 0.016
proton transport GO:0015992 35 0.016
divalent metal ion transport GO:0070838 172 0.015
response to endoplasmic reticulum stress GO:0034976 53 0.015
leukocyte differentiation GO:0002521 342 0.015
purine containing compound catabolic process GO:0072523 213 0.015
forebrain development GO:0030900 302 0.015
hormone secretion GO:0046879 128 0.015
synapse organization GO:0050808 125 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
response to copper ion GO:0046688 3 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
response to starvation GO:0042594 65 0.015
regulation of hydrolase activity GO:0051336 246 0.015
macromolecule deacylation GO:0098732 37 0.015
wnt signaling pathway GO:0016055 188 0.014
multicellular organism growth GO:0035264 161 0.014
regulation of cell division GO:0051302 76 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
protein refolding GO:0042026 1 0.014
nuclear division GO:0000280 158 0.014
carbohydrate homeostasis GO:0033500 128 0.014
methylation GO:0032259 134 0.014
regulation of protein transport GO:0051223 163 0.014
regulation of intracellular transport GO:0032386 159 0.014
cell adhesion GO:0007155 329 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
glucose homeostasis GO:0042593 128 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
regulation of cell cycle process GO:0010564 160 0.014
response to nutrient levels GO:0031667 109 0.013
endocytosis GO:0006897 168 0.013
Worm
cellular response to organonitrogen compound GO:0071417 145 0.013
response to organic cyclic compound GO:0014070 198 0.013
cellular lipid metabolic process GO:0044255 323 0.013
regulation of cytokine production GO:0001817 266 0.013
response to inorganic substance GO:0010035 96 0.013
regionalization GO:0003002 337 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
calcium ion transport GO:0006816 159 0.013
neuron apoptotic process GO:0051402 142 0.013
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.013
cellular response to starvation GO:0009267 57 0.013
regulation of ion transport GO:0043269 215 0.013
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
peptidyl lysine modification GO:0018205 77 0.013
regulation of chromatin organization GO:1902275 57 0.013
protein localization to nucleus GO:0034504 121 0.013
acetate ester transport GO:1901374 2 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
regulation of extent of cell growth GO:0061387 52 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
rna processing GO:0006396 105 0.013
neuronal action potential GO:0019228 54 0.013
smoothened signaling pathway GO:0007224 105 0.013
defense response to bacterium GO:0042742 119 0.013
chromosome segregation GO:0007059 48 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
skeletal muscle organ development GO:0060538 163 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
rna interference GO:0016246 2 0.012
locomotory behavior GO:0007626 195 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
response to lipopolysaccharide GO:0032496 128 0.012
peripheral nervous system development GO:0007422 53 0.012
negative regulation of cell development GO:0010721 169 0.012
membrane fusion GO:0061025 38 0.012
cell type specific apoptotic process GO:0097285 268 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
circulatory system process GO:0003013 197 0.012
meiotic nuclear division GO:0007126 115 0.012
skin development GO:0043588 220 0.012
positive regulation of organelle organization GO:0010638 128 0.012
melanosome localization GO:0032400 12 0.012
regulation of body fluid levels GO:0050878 162 0.012
single organism cell adhesion GO:0098602 156 0.012
antimicrobial peptide production GO:0002775 2 0.012
adult behavior GO:0030534 135 0.012
negative regulation of gene silencing GO:0060969 2 0.012
regulation of mapk cascade GO:0043408 248 0.012
protein deacetylation GO:0006476 32 0.012
metencephalon development GO:0022037 89 0.012
negative regulation of chromatin silencing GO:0031936 1 0.012
glandular epithelial cell maturation GO:0002071 2 0.012
regulation of kinase activity GO:0043549 249 0.011
action potential GO:0001508 78 0.011
response to growth factor GO:0070848 198 0.011
regulation of cellular response to stress GO:0080135 159 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
renal system development GO:0072001 225 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
dna repair GO:0006281 107 0.011
multicellular organismal signaling GO:0035637 91 0.011
myeloid cell differentiation GO:0030099 233 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
sequestering of calcium ion GO:0051208 18 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
placenta development GO:0001890 140 0.011
response to oxygen levels GO:0070482 62 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
gene silencing GO:0016458 38 0.011
regulation of chromosome organization GO:0033044 83 0.011
peptide secretion GO:0002790 114 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
innate immune response GO:0045087 157 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
regulation of membrane potential GO:0042391 192 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of cytoplasmic transport GO:1903649 112 0.010
hindbrain development GO:0030902 128 0.010
gtp catabolic process GO:0006184 143 0.010
lipoprotein metabolic process GO:0042157 43 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
amide transport GO:0042886 138 0.010
heart process GO:0003015 94 0.010
kidney development GO:0001822 213 0.010
regulation of endocytosis GO:0030100 69 0.010
phosphatidylinositol mediated signaling GO:0048015 41 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
forebrain cell migration GO:0021885 58 0.010
cerebellar cortex development GO:0021695 48 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
protein secretion GO:0009306 111 0.010
cerebellum morphogenesis GO:0021587 42 0.010
epidermis development GO:0008544 187 0.010
protein acylation GO:0043543 64 0.010
positive regulation of kinase activity GO:0033674 155 0.010
skeletal muscle cell differentiation GO:0035914 66 0.010
regulation of response to biotic stimulus GO:0002831 38 0.010
defense response to other organism GO:0098542 197 0.010
regulation of neuron differentiation GO:0045664 281 0.010
negative regulation of neuron death GO:1901215 98 0.010
mitochondrion degradation GO:0000422 3 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
pigment granule localization GO:0051875 13 0.010
atp metabolic process GO:0046034 75 0.010
response to extracellular stimulus GO:0009991 127 0.010
extracellular matrix organization GO:0030198 147 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010

Napa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
central nervous system disease DOID:331 0 0.012
immune system disease DOID:2914 0 0.011
neurodegenerative disease DOID:1289 0 0.011
disease of metabolism DOID:0014667 0 0.010
neuropathy DOID:870 0 0.010